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The map label for this gene is yyxA [H]

Identifier: 138897039

GI number: 138897039

Start: 3516395

End: 3517642

Strand: Reverse

Name: yyxA [H]

Synonym: GTNG_3410

Alternate gene names: 138897039

Gene position: 3517642-3516395 (Counterclockwise)

Preceding gene: 138897040

Following gene: 138897037

Centisome position: 99.08

GC content: 51.68

Gene sequence:

>1248_bases
ATGGAGATGAATGAGAAAGGGGTGGTGAGCATGGGATATTACGATGACCATTATGAACCGAATGGACAGACGAGACGAAA
ACGGCGCAGCGGTTCGTTCGTTTCTGCGCTTGTCGGTGCTATACTAGGAGGGCTGCTCGTCCTCATGTCCATCCCGACAC
TTTCCCGTTGGGACGTCCTCCCATATGAGGTTGTGCCGCCGCAGGGCGGAGAGGAAGAACGTGAAGGGGAAAACGGGGCT
CCCCCCATCCAGCAAAGTGTTTCTGTTGATGTGACAACAGCGGTAACGAAAGCGATCGATCAAGCGTCCGATGCGGTTGT
CGGCGTCGTCAATATTCAGGCAGCGGGTTTTTGGTCGCAAGGAGGCGAAGCCGGTGTTGGGTCGGGCGTTATTTATAAAA
AGGCTGGTGGCCGAGCGTTTGTTGTCACGAACCACCATGTCGTTGAAAACGCTAGCCAGTTGGAAGTGAGTTTAAAAGAT
GGAACGAGAGTGCCGGCCAAGCTGCTCGGCAGCGATGTGCTCATGGATTTAGCTGTGTTGGAAATTGACGCGAAACACGT
AAAAAAAGTCGCCCAATTCGGCAATTCTGATACAGTGAAGCTGGGTGAGCCGGTCATCGCTATCGGCAATCCGCTTGGTT
TACAGTTTGCTGGATCGGTGACGCAAGGAATTATTTCTGGGACGAACCGGACGGTGGAAGTCGACTTGGATCAAGACGGC
ACACCGGACTGGAACGCGGAAGTATTGCAGACAGACGCGGCGATTAACCCTGGCAACAGTGGCGGTGCTCTCGTGAACAT
GAAAGGACAAGTGATCGGAATTAATTCGATGAAAATTGCTCAAGAAGCGGTAGAAGGGATCGGATTTTCCATTCCGATCA
ATGCAGCCATCCCGATTATTTCCGACTTGGAAAAATACGGACAAGTACGTCGGCCATACATGGGGGTAGAGCTCCGCTCA
CTCAGCGACATCCCATCGTACCATTTGAAGGCGACGCTTCATTTACCGTCGAACGTGACAGAAGGAGTAGCAGTCATCCA
AGTTGTGCCGATGTCGCCGGCTGCGCAAGCAGGTTTGCAGCAGTTTGACGTCATCGTGGCACTAGACGGCGAAAAAGTCC
GTAACGTGCTTGATTTACGCAAGTATTTGTATACGAAAAAATCAGTTGGAGAGCAAATGGAAGTCACGTTTTATCGTGAT
GGGAAAAAGCGGACGATCACGATGAAACTGGCGCCCGAGTCGTACTAA

Upstream 100 bases:

>100_bases
GTCAAGCGACAGCGTTGGCGTATGTGTGATGCCTCTTTTGTCTAAACTGAAGAAAATGCATTTGTTGGATTTTTTGTCCT
GCTCATGATTATAATGAGGG

Downstream 100 bases:

>100_bases
ACAAAAAAAACAGCGAAGGGAGCGGGAACGCTCCTTCTTTTTTCCACAAGGAAAGGGGCGAGAAAGATGATATTCACATG
TGAAGAACATATTGATATCG

Product: Serine protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MEMNEKGVVSMGYYDDHYEPNGQTRRKRRSGSFVSALVGAILGGLLVLMSIPTLSRWDVLPYEVVPPQGGEEEREGENGA
PPIQQSVSVDVTTAVTKAIDQASDAVVGVVNIQAAGFWSQGGEAGVGSGVIYKKAGGRAFVVTNHHVVENASQLEVSLKD
GTRVPAKLLGSDVLMDLAVLEIDAKHVKKVAQFGNSDTVKLGEPVIAIGNPLGLQFAGSVTQGIISGTNRTVEVDLDQDG
TPDWNAEVLQTDAAINPGNSGGALVNMKGQVIGINSMKIAQEAVEGIGFSIPINAAIPIISDLEKYGQVRRPYMGVELRS
LSDIPSYHLKATLHLPSNVTEGVAVIQVVPMSPAAQAGLQQFDVIVALDGEKVRNVLDLRKYLYTKKSVGEQMEVTFYRD
GKKRTITMKLAPESY

Sequences:

>Translated_415_residues
MEMNEKGVVSMGYYDDHYEPNGQTRRKRRSGSFVSALVGAILGGLLVLMSIPTLSRWDVLPYEVVPPQGGEEEREGENGA
PPIQQSVSVDVTTAVTKAIDQASDAVVGVVNIQAAGFWSQGGEAGVGSGVIYKKAGGRAFVVTNHHVVENASQLEVSLKD
GTRVPAKLLGSDVLMDLAVLEIDAKHVKKVAQFGNSDTVKLGEPVIAIGNPLGLQFAGSVTQGIISGTNRTVEVDLDQDG
TPDWNAEVLQTDAAINPGNSGGALVNMKGQVIGINSMKIAQEAVEGIGFSIPINAAIPIISDLEKYGQVRRPYMGVELRS
LSDIPSYHLKATLHLPSNVTEGVAVIQVVPMSPAAQAGLQQFDVIVALDGEKVRNVLDLRKYLYTKKSVGEQMEVTFYRD
GKKRTITMKLAPESY
>Mature_415_residues
MEMNEKGVVSMGYYDDHYEPNGQTRRKRRSGSFVSALVGAILGGLLVLMSIPTLSRWDVLPYEVVPPQGGEEEREGENGA
PPIQQSVSVDVTTAVTKAIDQASDAVVGVVNIQAAGFWSQGGEAGVGSGVIYKKAGGRAFVVTNHHVVENASQLEVSLKD
GTRVPAKLLGSDVLMDLAVLEIDAKHVKKVAQFGNSDTVKLGEPVIAIGNPLGLQFAGSVTQGIISGTNRTVEVDLDQDG
TPDWNAEVLQTDAAINPGNSGGALVNMKGQVIGINSMKIAQEAVEGIGFSIPINAAIPIISDLEKYGQVRRPYMGVELRS
LSDIPSYHLKATLHLPSNVTEGVAVIQVVPMSPAAQAGLQQFDVIVALDGEKVRNVLDLRKYLYTKKSVGEQMEVTFYRD
GKKRTITMKLAPESY

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=290, Percent_Identity=33.1034482758621, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI24308541, Length=330, Percent_Identity=32.1212121212121, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI7019477, Length=328, Percent_Identity=34.1463414634146, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI22129776, Length=328, Percent_Identity=30.1829268292683, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1786356, Length=294, Percent_Identity=37.0748299319728, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1789629, Length=291, Percent_Identity=34.7079037800687, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1789630, Length=292, Percent_Identity=36.6438356164384, Blast_Score=147, Evalue=9e-37,
Organism=Drosophila melanogaster, GI24646839, Length=312, Percent_Identity=33.974358974359, Blast_Score=139, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 44323; Mature: 44323

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMNEKGVVSMGYYDDHYEPNGQTRRKRRSGSFVSALVGAILGGLLVLMSIPTLSRWDVL
CCCCCCCCEEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PYEVVPPQGGEEEREGENGAPPIQQSVSVDVTTAVTKAIDQASDAVVGVVNIQAAGFWSQ
CEEEECCCCCCHHHCCCCCCCCCHHCCEEEHHHHHHHHHHHCCCCEEEEEEEEEECCCCC
GGEAGVGSGVIYKKAGGRAFVVTNHHVVENASQLEVSLKDGTRVPAKLLGSDVLMDLAVL
CCCCCCCCCEEEEECCCEEEEEECCHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHE
EIDAKHVKKVAQFGNSDTVKLGEPVIAIGNPLGLQFAGSVTQGIISGTNRTVEVDLDQDG
EECHHHHHHHHHCCCCCEEEECCCEEEECCCCCEEECCHHHHHHHCCCCEEEEEEECCCC
TPDWNAEVLQTDAAINPGNSGGALVNMKGQVIGINSMKIAQEAVEGIGFSIPINAAIPII
CCCCCCEEEEECCCCCCCCCCCEEEEECCCEEECCHHHHHHHHHHHCCEEEECCCCCHHH
SDLEKYGQVRRPYMGVELRSLSDIPSYHLKATLHLPSNVTEGVAVIQVVPMSPAAQAGLQ
HHHHHHHHHCCCCCCEEEHHHCCCCCEEEEEEEECCCCCCCCEEEEEEECCCCHHHHCHH
QFDVIVALDGEKVRNVLDLRKYLYTKKSVGEQMEVTFYRDGKKRTITMKLAPESY
HEEEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEEEECCCCC
>Mature Secondary Structure
MEMNEKGVVSMGYYDDHYEPNGQTRRKRRSGSFVSALVGAILGGLLVLMSIPTLSRWDVL
CCCCCCCCEEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PYEVVPPQGGEEEREGENGAPPIQQSVSVDVTTAVTKAIDQASDAVVGVVNIQAAGFWSQ
CEEEECCCCCCHHHCCCCCCCCCHHCCEEEHHHHHHHHHHHCCCCEEEEEEEEEECCCCC
GGEAGVGSGVIYKKAGGRAFVVTNHHVVENASQLEVSLKDGTRVPAKLLGSDVLMDLAVL
CCCCCCCCCEEEEECCCEEEEEECCHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHE
EIDAKHVKKVAQFGNSDTVKLGEPVIAIGNPLGLQFAGSVTQGIISGTNRTVEVDLDQDG
EECHHHHHHHHHCCCCCEEEECCCEEEECCCCCEEECCHHHHHHHCCCCEEEEEEECCCC
TPDWNAEVLQTDAAINPGNSGGALVNMKGQVIGINSMKIAQEAVEGIGFSIPINAAIPII
CCCCCCEEEEECCCCCCCCCCCEEEEECCCEEECCHHHHHHHHHHHCCEEEECCCCCHHH
SDLEKYGQVRRPYMGVELRSLSDIPSYHLKATLHLPSNVTEGVAVIQVVPMSPAAQAGLQ
HHHHHHHHHCCCCCCEEEHHHCCCCCEEEEEEEECCCCCCCCEEEEEEECCCCHHHHCHH
QFDVIVALDGEKVRNVLDLRKYLYTKKSVGEQMEVTFYRDGKKRTITMKLAPESY
HEEEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8113162 [H]