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The map label for this gene is ytnA [H]

Identifier: 138897022

GI number: 138897022

Start: 3500402

End: 3501790

Strand: Direct

Name: ytnA [H]

Synonym: GTNG_3393

Alternate gene names: 138897022

Gene position: 3500402-3501790 (Clockwise)

Preceding gene: 138897016

Following gene: 138897026

Centisome position: 98.59

GC content: 48.24

Gene sequence:

>1389_bases
ATGGAGCAAAAGCAGCCGCAATTGCATCGAGGATTGGAAGAACGCCACATTTCGCTCATGTCGCTCGGCGCAGCGATTGG
CGTTGGCTTGTTCCTTGGTTCGGCATCCGCAATTGAAATGGCTGGGCCGGCGATTTTGCTTGGCTATGCGATCAGCGGTG
CCATTATGTTTTTTATCATGCGAGCATTAGGTGAAATGGCGGTCGAACATCCGGTTGCCGGTTCGTTCAGCCGTTATGCG
CATAACTATTTAGGGCCGCTCGCCGGTTATTTGACCGGTTGGAACTATTGGTTTTTATGGGTTGTCACATGTATCGCTGA
GATTACAGCCGTTGGTATTTATATGCAGTTTTGGTTCCCTGATACACCACGTTGGGCATGGGCGCTCGCTGCCCTTGTAC
TCATGACGTCCATTAACTTCCTTGCCGTAAAAGCGTATGGGGAGTTTGAGTTTTGGTTTGCTTTGATCAAGATTGTCACG
ATCATCGCCATGATTGTCGTTGGCTTAGGAATGATTATATTCGGCATCGGCAACGGCGGTATCGCCACCGGTATTAGTAA
TCTTTGGAAACACGGCGGCTTTTTCCCGAACGGGATTAGCGGTGTGCTCATGTCGCTGCAAATGGTCGTGTTCGCCTATT
TAGGCATCGAAATGATCGGTGTCACAGCAGGAGAAGTGAAAAATCCGCAAAAATCGTTGACAAAAGCCATTAATACTGTG
TTTTGGCGTATTTTAATTTTCTACGTCGGTGCATTGTTCGTCATTATGTCCATTTACCCTTGGAATGAAATTGGTCAAAA
AGGGAGCCCGTTTGTGTTGACATTTGAAAAAGTCGGCATTCATGCCGCCGCGGGTATCATTAACTTTGTCGTCTTGACGG
CTGCCCTGTCGTCGTGCAACAGTGGTATTTTCAGCACGAGCCGGATGCTGTTTAACCTGTCCGAACAAAAAGAGGCGCCA
CAAGCATTTAGCCGTTTAACTAACCGCGGCATCCCTGGCACCGCTTTGATCGTCACCGCCCTTGCCATGCTGGTCGGCGT
CTATTTGAACTACGTATCGGAAAAAGTGTTCCAATGGGTGACAAGTATCGCAACGTTCGGCGCTATTTGGACGTGGTCCA
TTATTTTGCTTTCCCAACTGAAGTTCCGTAAGCAGCTTAGCGCAGAACAAGTGAAACGACTAGCATTCAAAATGCCATTT
TATCCGTACAGCTCTTATGTATCGCTTGCCTTCTTAATTGGTGTCATCATCTTAATGGCGTATTTCCCGGATACGCGCAT
CGCATTGATCGTCGGCCCAACGTGGTTGCTGTTGCTGACAGCGATCTACTTCATTAAAGGAATGCACCGCCGCGAACACC
GCGAGCAAGAGAAAAAGCAAGCTGTATAA

Upstream 100 bases:

>100_bases
TACAAATCGTTGTCATATCGATTACTATTATATTGTAAGCGCTTTATGAAAACTTTTTCGCAAAATATTATTTATTATCA
ATTGCTAGGAGGAAAAATAG

Downstream 100 bases:

>100_bases
TAAATGCAGTGACCCCTGTCAAGTAGACAGGAAGAAAAAAGCCCATTTAAACACCCTCAGTTCTGTATTCATACGGACTC
AGGGTGTTTTATTTTTTGGA

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MEQKQPQLHRGLEERHISLMSLGAAIGVGLFLGSASAIEMAGPAILLGYAISGAIMFFIMRALGEMAVEHPVAGSFSRYA
HNYLGPLAGYLTGWNYWFLWVVTCIAEITAVGIYMQFWFPDTPRWAWALAALVLMTSINFLAVKAYGEFEFWFALIKIVT
IIAMIVVGLGMIIFGIGNGGIATGISNLWKHGGFFPNGISGVLMSLQMVVFAYLGIEMIGVTAGEVKNPQKSLTKAINTV
FWRILIFYVGALFVIMSIYPWNEIGQKGSPFVLTFEKVGIHAAAGIINFVVLTAALSSCNSGIFSTSRMLFNLSEQKEAP
QAFSRLTNRGIPGTALIVTALAMLVGVYLNYVSEKVFQWVTSIATFGAIWTWSIILLSQLKFRKQLSAEQVKRLAFKMPF
YPYSSYVSLAFLIGVIILMAYFPDTRIALIVGPTWLLLLTAIYFIKGMHRREHREQEKKQAV

Sequences:

>Translated_462_residues
MEQKQPQLHRGLEERHISLMSLGAAIGVGLFLGSASAIEMAGPAILLGYAISGAIMFFIMRALGEMAVEHPVAGSFSRYA
HNYLGPLAGYLTGWNYWFLWVVTCIAEITAVGIYMQFWFPDTPRWAWALAALVLMTSINFLAVKAYGEFEFWFALIKIVT
IIAMIVVGLGMIIFGIGNGGIATGISNLWKHGGFFPNGISGVLMSLQMVVFAYLGIEMIGVTAGEVKNPQKSLTKAINTV
FWRILIFYVGALFVIMSIYPWNEIGQKGSPFVLTFEKVGIHAAAGIINFVVLTAALSSCNSGIFSTSRMLFNLSEQKEAP
QAFSRLTNRGIPGTALIVTALAMLVGVYLNYVSEKVFQWVTSIATFGAIWTWSIILLSQLKFRKQLSAEQVKRLAFKMPF
YPYSSYVSLAFLIGVIILMAYFPDTRIALIVGPTWLLLLTAIYFIKGMHRREHREQEKKQAV
>Mature_462_residues
MEQKQPQLHRGLEERHISLMSLGAAIGVGLFLGSASAIEMAGPAILLGYAISGAIMFFIMRALGEMAVEHPVAGSFSRYA
HNYLGPLAGYLTGWNYWFLWVVTCIAEITAVGIYMQFWFPDTPRWAWALAALVLMTSINFLAVKAYGEFEFWFALIKIVT
IIAMIVVGLGMIIFGIGNGGIATGISNLWKHGGFFPNGISGVLMSLQMVVFAYLGIEMIGVTAGEVKNPQKSLTKAINTV
FWRILIFYVGALFVIMSIYPWNEIGQKGSPFVLTFEKVGIHAAAGIINFVVLTAALSSCNSGIFSTSRMLFNLSEQKEAP
QAFSRLTNRGIPGTALIVTALAMLVGVYLNYVSEKVFQWVTSIATFGAIWTWSIILLSQLKFRKQLSAEQVKRLAFKMPF
YPYSSYVSLAFLIGVIILMAYFPDTRIALIVGPTWLLLLTAIYFIKGMHRREHREQEKKQAV

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258645169, Length=427, Percent_Identity=21.0772833723653, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI258614005, Length=427, Percent_Identity=20.6088992974239, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI181337167, Length=320, Percent_Identity=23.4375, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI258614003, Length=427, Percent_Identity=20.6088992974239, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI110347453, Length=345, Percent_Identity=23.1884057971014, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI48994972, Length=462, Percent_Identity=51.7316017316017, Blast_Score=473, Evalue=1e-134,
Organism=Escherichia coli, GI1786602, Length=458, Percent_Identity=54.8034934497817, Blast_Score=464, Evalue=1e-132,
Organism=Escherichia coli, GI1786789, Length=439, Percent_Identity=45.5580865603645, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1786302, Length=448, Percent_Identity=45.0892857142857, Blast_Score=405, Evalue=1e-114,
Organism=Escherichia coli, GI1790653, Length=456, Percent_Identity=45.6140350877193, Blast_Score=401, Evalue=1e-113,
Organism=Escherichia coli, GI87081915, Length=475, Percent_Identity=38.7368421052632, Blast_Score=331, Evalue=6e-92,
Organism=Escherichia coli, GI87081708, Length=463, Percent_Identity=37.5809935205184, Blast_Score=318, Evalue=7e-88,
Organism=Escherichia coli, GI1789017, Length=432, Percent_Identity=36.1111111111111, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1788480, Length=484, Percent_Identity=35.1239669421488, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI87081869, Length=339, Percent_Identity=20.0589970501475, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87082023, Length=193, Percent_Identity=23.3160621761658, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17532491, Length=422, Percent_Identity=20.1421800947867, Blast_Score=68, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6324061, Length=440, Percent_Identity=33.4090909090909, Blast_Score=250, Evalue=3e-67,
Organism=Saccharomyces cerevisiae, GI6320772, Length=441, Percent_Identity=34.4671201814059, Blast_Score=243, Evalue=4e-65,
Organism=Saccharomyces cerevisiae, GI6324924, Length=446, Percent_Identity=32.2869955156951, Blast_Score=221, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6322892, Length=437, Percent_Identity=32.4942791762014, Blast_Score=218, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6324059, Length=440, Percent_Identity=32.5, Blast_Score=208, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6319824, Length=439, Percent_Identity=30.2961275626424, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6324990, Length=440, Percent_Identity=30.6818181818182, Blast_Score=201, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6320717, Length=405, Percent_Identity=28.1481481481481, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6324553, Length=426, Percent_Identity=31.924882629108, Blast_Score=181, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6321629, Length=415, Percent_Identity=28.1927710843373, Blast_Score=181, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6320251, Length=438, Percent_Identity=28.5388127853881, Blast_Score=179, Evalue=8e-46,
Organism=Saccharomyces cerevisiae, GI6319542, Length=411, Percent_Identity=29.4403892944039, Blast_Score=176, Evalue=8e-45,
Organism=Saccharomyces cerevisiae, GI6321053, Length=469, Percent_Identity=26.865671641791, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6322967, Length=401, Percent_Identity=25.1870324189526, Blast_Score=164, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6319543, Length=435, Percent_Identity=26.6666666666667, Blast_Score=163, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6319608, Length=444, Percent_Identity=27.2522522522523, Blast_Score=159, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6324981, Length=400, Percent_Identity=25, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320364, Length=503, Percent_Identity=23.8568588469185, Blast_Score=126, Evalue=7e-30,
Organism=Drosophila melanogaster, GI221512776, Length=342, Percent_Identity=22.5146198830409, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24666159, Length=342, Percent_Identity=22.5146198830409, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24667468, Length=363, Percent_Identity=22.8650137741047, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161077963, Length=364, Percent_Identity=23.3516483516484, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281366235, Length=409, Percent_Identity=22.2493887530562, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI116007820, Length=409, Percent_Identity=22.2493887530562, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51161; Mature: 51161

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQKQPQLHRGLEERHISLMSLGAAIGVGLFLGSASAIEMAGPAILLGYAISGAIMFFIM
CCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHH
RALGEMAVEHPVAGSFSRYAHNYLGPLAGYLTGWNYWFLWVVTCIAEITAVGIYMQFWFP
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHEEECC
DTPRWAWALAALVLMTSINFLAVKAYGEFEFWFALIKIVTIIAMIVVGLGMIIFGIGNGG
CCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
IATGISNLWKHGGFFPNGISGVLMSLQMVVFAYLGIEMIGVTAGEVKNPQKSLTKAINTV
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHH
FWRILIFYVGALFVIMSIYPWNEIGQKGSPFVLTFEKVGIHAAAGIINFVVLTAALSSCN
HHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
SGIFSTSRMLFNLSEQKEAPQAFSRLTNRGIPGTALIVTALAMLVGVYLNYVSEKVFQWV
CCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSIATFGAIWTWSIILLSQLKFRKQLSAEQVKRLAFKMPFYPYSSYVSLAFLIGVIILMA
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
YFPDTRIALIVGPTWLLLLTAIYFIKGMHRREHREQEKKQAV
HCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEQKQPQLHRGLEERHISLMSLGAAIGVGLFLGSASAIEMAGPAILLGYAISGAIMFFIM
CCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHH
RALGEMAVEHPVAGSFSRYAHNYLGPLAGYLTGWNYWFLWVVTCIAEITAVGIYMQFWFP
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHEEECC
DTPRWAWALAALVLMTSINFLAVKAYGEFEFWFALIKIVTIIAMIVVGLGMIIFGIGNGG
CCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
IATGISNLWKHGGFFPNGISGVLMSLQMVVFAYLGIEMIGVTAGEVKNPQKSLTKAINTV
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHH
FWRILIFYVGALFVIMSIYPWNEIGQKGSPFVLTFEKVGIHAAAGIINFVVLTAALSSCN
HHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
SGIFSTSRMLFNLSEQKEAPQAFSRLTNRGIPGTALIVTALAMLVGVYLNYVSEKVFQWV
CCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSIATFGAIWTWSIILLSQLKFRKQLSAEQVKRLAFKMPFYPYSSYVSLAFLIGVIILMA
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
YFPDTRIALIVGPTWLLLLTAIYFIKGMHRREHREQEKKQAV
HCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]