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The map label for this gene is yesM [H]

Identifier: 138896765

GI number: 138896765

Start: 3228345

End: 3229790

Strand: Reverse

Name: yesM [H]

Synonym: GTNG_3128

Alternate gene names: 138896765

Gene position: 3229790-3228345 (Counterclockwise)

Preceding gene: 138896766

Following gene: 138896764

Centisome position: 90.97

GC content: 50.07

Gene sequence:

>1446_bases
ATGAACATCCGCACAAAGATGTTGCTTTGTTTTACCGTTTTTTTGCTTTTGTTAAATGGAGCGGTGTTTCTTTTATATCA
AACTAGTGAAGAGATGATGAGTGATTATGATCGCCGGATGCGCCGATTGTTGTTGCTGAATGAAGTGTCGCAACGGACAA
ACCGGTTGATGGAGCAGCTGAATGCGTATGTATCGGAAAAAGAGGGGCGATACGCGCGCGCCTATGAGCAGGAGGTACAC
TGGCTGCAACAACACCGCCGCCAAGTTGGTGCTATCTTGCCGATATTGTCTGACCGGTTGGCAGCAGAAAACTATGAACA
TATGATCGAAAGTTTGTTAGAGGAAGCAGCGCTCACGGTCTACCATTTTCAGGCCGGAAATATTAGCTTGTACTCATCCC
ATCTGCATGAAACGATGAATATTGCCCTTTTTTTGCAGGAAGAAACGTTAAACTTAATTGATGATGAGTTAACGGCTTAT
CAACGACGGTACGATGAAGTCGAACAGCGTAACCACTATTTCCGGTATATGGGAATGGGGTTGTTTGCGACAACGCTTTG
CTTCGGTGTGCTTCTTGCTGTGTTTTTCTCCGGCAGTTTGACGAGGCCGATCATCCAGCTTGCACATGTAGCCCGAGAGA
TCGGCGCCGGACGGCTCGATGGGCCAGATGTAAATCCGACAACGAATGATGAACTGCGGCTGCTCACGATCACCTTTAAT
GACATGCGCCGCAATTTAAAACAGCTGATTGCAGAAATGAAACAAAAAGCCGAGCTCGACCGGCTTGTGAAGGAGCTGGA
GCTTAAAAGTTTGCAAAGCCAAATCAATCCGCACTTTTTGTTCAATACGTTGAATACGGTCGCGAAGATGGCGTATTTGG
AGGACGCCCCACAAACATCGAGGCTGATTGAGGCAGTGGCAGCGATTTTACGCTACAATCTGGGCGATTTGCAGCGGACG
GTGACGCTTGCCGATGAGGTGCGCGTTGCTCGCGAATATTTTTTCATTCAGCAAACGCGCTTTTTTGACCGGATCAAGTT
TTCTCTTGAGGCAGAGCCGTCTTGTCTTGGCCAGCGGCTTCCGCCTTTGACGTTGCAACCGCTGATTGAAAATGCGTTCA
TTCATGGCATCGAATCATATGAACAAGGGGCGGAACTGACGGTGTCGATTGCCGAAGGAGAGAGCCGGGTGATCGTGGAA
GTGCGCGACAATGGAGTCGGAATGGACGAGCAAGTGAAAACGGAATTTGAGGCGTTCATTCGCGGGGAAGAGAGGGAATC
GCGCCGCGAGGAAGGGCGCGGCCATTCGACCGGCATCGGTTTGCGCAATGTCATTCGCCGCTTGCAATTGTTTTATGGCG
TCACCGATGTGGTAGATATCGAGTCGGCGCCGGGGAGAGGAACGACTATCCGGCTGCGGTTGCCCAAATGGACGAAGGAG
GGATGA

Upstream 100 bases:

>100_bases
TCATTGGTTGGATCAACTTGATGTCCGAGAAAGTTTGACTTGAAGCGGTACAAAGATGATGTAGACAACAAAGCGCTGGT
GACAGCGGGGGGAAGCTAGG

Downstream 100 bases:

>100_bases
GCGATGAATGTGGTGATCGTCGATGATGAAGCATTGGAGCGCAAGGCGCTTTGCAAAATGATTCGCGACCATCTACCCGA
GATGGAAGTGGTGGCGGAGG

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MNIRTKMLLCFTVFLLLLNGAVFLLYQTSEEMMSDYDRRMRRLLLLNEVSQRTNRLMEQLNAYVSEKEGRYARAYEQEVH
WLQQHRRQVGAILPILSDRLAAENYEHMIESLLEEAALTVYHFQAGNISLYSSHLHETMNIALFLQEETLNLIDDELTAY
QRRYDEVEQRNHYFRYMGMGLFATTLCFGVLLAVFFSGSLTRPIIQLAHVAREIGAGRLDGPDVNPTTNDELRLLTITFN
DMRRNLKQLIAEMKQKAELDRLVKELELKSLQSQINPHFLFNTLNTVAKMAYLEDAPQTSRLIEAVAAILRYNLGDLQRT
VTLADEVRVAREYFFIQQTRFFDRIKFSLEAEPSCLGQRLPPLTLQPLIENAFIHGIESYEQGAELTVSIAEGESRVIVE
VRDNGVGMDEQVKTEFEAFIRGEERESRREEGRGHSTGIGLRNVIRRLQLFYGVTDVVDIESAPGRGTTIRLRLPKWTKE
G

Sequences:

>Translated_481_residues
MNIRTKMLLCFTVFLLLLNGAVFLLYQTSEEMMSDYDRRMRRLLLLNEVSQRTNRLMEQLNAYVSEKEGRYARAYEQEVH
WLQQHRRQVGAILPILSDRLAAENYEHMIESLLEEAALTVYHFQAGNISLYSSHLHETMNIALFLQEETLNLIDDELTAY
QRRYDEVEQRNHYFRYMGMGLFATTLCFGVLLAVFFSGSLTRPIIQLAHVAREIGAGRLDGPDVNPTTNDELRLLTITFN
DMRRNLKQLIAEMKQKAELDRLVKELELKSLQSQINPHFLFNTLNTVAKMAYLEDAPQTSRLIEAVAAILRYNLGDLQRT
VTLADEVRVAREYFFIQQTRFFDRIKFSLEAEPSCLGQRLPPLTLQPLIENAFIHGIESYEQGAELTVSIAEGESRVIVE
VRDNGVGMDEQVKTEFEAFIRGEERESRREEGRGHSTGIGLRNVIRRLQLFYGVTDVVDIESAPGRGTTIRLRLPKWTKE
G
>Mature_481_residues
MNIRTKMLLCFTVFLLLLNGAVFLLYQTSEEMMSDYDRRMRRLLLLNEVSQRTNRLMEQLNAYVSEKEGRYARAYEQEVH
WLQQHRRQVGAILPILSDRLAAENYEHMIESLLEEAALTVYHFQAGNISLYSSHLHETMNIALFLQEETLNLIDDELTAY
QRRYDEVEQRNHYFRYMGMGLFATTLCFGVLLAVFFSGSLTRPIIQLAHVAREIGAGRLDGPDVNPTTNDELRLLTITFN
DMRRNLKQLIAEMKQKAELDRLVKELELKSLQSQINPHFLFNTLNTVAKMAYLEDAPQTSRLIEAVAAILRYNLGDLQRT
VTLADEVRVAREYFFIQQTRFFDRIKFSLEAEPSCLGQRLPPLTLQPLIENAFIHGIESYEQGAELTVSIAEGESRVIVE
VRDNGVGMDEQVKTEFEAFIRGEERESRREEGRGHSTGIGLRNVIRRLQLFYGVTDVVDIESAPGRGTTIRLRLPKWTKE
G

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=227, Percent_Identity=35.2422907488987, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788446, Length=254, Percent_Identity=29.1338582677165, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55538; Mature: 55538

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRTKMLLCFTVFLLLLNGAVFLLYQTSEEMMSDYDRRMRRLLLLNEVSQRTNRLMEQL
CCCHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAYVSEKEGRYARAYEQEVHWLQQHRRQVGAILPILSDRLAAENYEHMIESLLEEAALTV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
YHFQAGNISLYSSHLHETMNIALFLQEETLNLIDDELTAYQRRYDEVEQRNHYFRYMGMG
EEEECCCEEHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LFATTLCFGVLLAVFFSGSLTRPIIQLAHVAREIGAGRLDGPDVNPTTNDELRLLTITFN
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEHH
DMRRNLKQLIAEMKQKAELDRLVKELELKSLQSQINPHFLFNTLNTVAKMAYLEDAPQTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHH
RLIEAVAAILRYNLGDLQRTVTLADEVRVAREYFFIQQTRFFDRIKFSLEAEPSCLGQRL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC
PPLTLQPLIENAFIHGIESYEQGAELTVSIAEGESRVIVEVRDNGVGMDEQVKTEFEAFI
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHH
RGEERESRREEGRGHSTGIGLRNVIRRLQLFYGVTDVVDIESAPGRGTTIRLRLPKWTKE
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHEECCCCCCCCCEEEEECCCCCCC
G
C
>Mature Secondary Structure
MNIRTKMLLCFTVFLLLLNGAVFLLYQTSEEMMSDYDRRMRRLLLLNEVSQRTNRLMEQL
CCCHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAYVSEKEGRYARAYEQEVHWLQQHRRQVGAILPILSDRLAAENYEHMIESLLEEAALTV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
YHFQAGNISLYSSHLHETMNIALFLQEETLNLIDDELTAYQRRYDEVEQRNHYFRYMGMG
EEEECCCEEHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LFATTLCFGVLLAVFFSGSLTRPIIQLAHVAREIGAGRLDGPDVNPTTNDELRLLTITFN
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEHH
DMRRNLKQLIAEMKQKAELDRLVKELELKSLQSQINPHFLFNTLNTVAKMAYLEDAPQTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHH
RLIEAVAAILRYNLGDLQRTVTLADEVRVAREYFFIQQTRFFDRIKFSLEAEPSCLGQRL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC
PPLTLQPLIENAFIHGIESYEQGAELTVSIAEGESRVIVEVRDNGVGMDEQVKTEFEAFI
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHH
RGEERESRREEGRGHSTGIGLRNVIRRLQLFYGVTDVVDIESAPGRGTTIRLRLPKWTKE
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHEECCCCCCCCCEEEEECCCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]