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The map label for this gene is comFA [H]

Identifier: 138896709

GI number: 138896709

Start: 3166399

End: 3167775

Strand: Reverse

Name: comFA [H]

Synonym: GTNG_3072

Alternate gene names: 138896709

Gene position: 3167775-3166399 (Counterclockwise)

Preceding gene: 138896710

Following gene: 138896708

Centisome position: 89.23

GC content: 56.43

Gene sequence:

>1377_bases
TTGTCTGTTTCTTCACCGCTTATAGCATCGCTATACGGTCAGCGGATTCCGCGAGAACAACTCCCATTTTCCCATGCCGA
TATTGAGACAGCCTTGCGTGTTGGTTCGCTTCATGAACAGTCAGGTTTGATCAAAACACCCCGTGGTTGGCGCTGTGTGC
GCTGCGGAAATGATGAACGGTCATGGTTCGCTTCATTTCCGTGCGCTCGCTGCGGGACGAATTGTTGTTATTGTCGCAAA
TGTTTGATGATGGGTCGCATCAGTTCTTGCACCCGCTTGGTACATGTGACGATGTCGCTTCCGTCAGAACGATATGCAGT
GCCGCTCGCTTGGAACGGAACGCTATCCGCCGCTCAGGAGGAGGCAGCTATGGAGGTCAAACAGGCAGTTCTCAACAGGA
GGGAGCTGCTTGTTTGGGCTGTATGCGGGGCGGGAAAAACGGAGATTTTGTTTCCTGCCATCGCCGCCGCATTGGAGGAA
GGTTGGCGTGTCTGCCTCGCCACGCCAAGAATTGATGTCGTCCGCGAGCTCGCTCCCCGCTTTCGCCAAGCGTTTCCTCG
CGTTCCGCTCGCCGTTTGGTACGGAGGAAGCGAGGAGCGCGGGCAGATCGCCCCGCTCGTTCTTTCCACTACCCACCAAC
TGTTGCGTGCGTATCGTGTGTTTGATGTCATGATCATCGATGAAGTCGATGCATTTCCGTATTCGGTTGAACCGATGCTG
GAATATGCTGTCAGTCAGGCACGGAAAGAACAATCGAGCCTCATTTATTTAACCGCCACCCCATCCCGAGCTTGGCAACT
TGACGTTCAGTGTGGCAAGCGGCAAGCCGCCGTCATCCCCGCCCGCTACCACGGCCATCCACTTCCTGTCCCATCGTTCG
AATGGTGCGGAAACTGGCGCAAACGGCTCGAGCGCGGCCGTTTGCCCGAAAACGTCCTCGCTTGGGTTCTTCGTCGTTTG
GAACAAAGAAAGCAAGCGTTTTTGTTCGTCCCACACATCGATGAATTGGAAGCGGTCACTCGCCTGTTGCAGCGGGTGGA
CGCTCGCATCGTCGGTGTTCACGCTGAAGCCCCCGCCCGCGCTGAATATGTGCAGGCGTTTCGCGATGGGAGCGTACCGC
TGTTGGTCACAACGACGATCCTTGAACGAGGTGTGACCGTGCCTAACATCGATGTCGCCGTCCTTGGTGCGGAAGACCGA
ATTTTTACGGAAAGTGCCCTCGTCCAAATCGCGGGCCGCGTCGGGAGAAGCGCCGCATTTCCCGATGGGGACGTCCGCTT
TTTCCACCATGGGAAAACAACCGAGATGGTACGGGCGCACCGCCATATTGTCCGCATGAACGAGACAGCGCAGAAAAGGG
GGCTGTTGCATCGATGA

Upstream 100 bases:

>100_bases
CTTAAAAACATTGTCAATATTTCCCCGGGAATTTTGTCGAAAAAAGCTAATTGTCGCAAGAATACTACCCATATGTCGAA
TGAAAAAGGGGGGATCATGA

Downstream 100 bases:

>100_bases
ATTGTCTTCTTTGTCATTCCTCGTACAACCCGATCGCCAGCTGGCGCCAACTTCTTTTTCTCGAAGACGTTGATGTCCTT
TGCCCGCGTTGCCGCGGTTC

Product: ComF operon protein 1

Products: NA

Alternate protein names: ATP-dependent helicase ComFA [H]

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MSVSSPLIASLYGQRIPREQLPFSHADIETALRVGSLHEQSGLIKTPRGWRCVRCGNDERSWFASFPCARCGTNCCYCRK
CLMMGRISSCTRLVHVTMSLPSERYAVPLAWNGTLSAAQEEAAMEVKQAVLNRRELLVWAVCGAGKTEILFPAIAAALEE
GWRVCLATPRIDVVRELAPRFRQAFPRVPLAVWYGGSEERGQIAPLVLSTTHQLLRAYRVFDVMIIDEVDAFPYSVEPML
EYAVSQARKEQSSLIYLTATPSRAWQLDVQCGKRQAAVIPARYHGHPLPVPSFEWCGNWRKRLERGRLPENVLAWVLRRL
EQRKQAFLFVPHIDELEAVTRLLQRVDARIVGVHAEAPARAEYVQAFRDGSVPLLVTTTILERGVTVPNIDVAVLGAEDR
IFTESALVQIAGRVGRSAAFPDGDVRFFHHGKTTEMVRAHRHIVRMNETAQKRGLLHR

Sequences:

>Translated_458_residues
MSVSSPLIASLYGQRIPREQLPFSHADIETALRVGSLHEQSGLIKTPRGWRCVRCGNDERSWFASFPCARCGTNCCYCRK
CLMMGRISSCTRLVHVTMSLPSERYAVPLAWNGTLSAAQEEAAMEVKQAVLNRRELLVWAVCGAGKTEILFPAIAAALEE
GWRVCLATPRIDVVRELAPRFRQAFPRVPLAVWYGGSEERGQIAPLVLSTTHQLLRAYRVFDVMIIDEVDAFPYSVEPML
EYAVSQARKEQSSLIYLTATPSRAWQLDVQCGKRQAAVIPARYHGHPLPVPSFEWCGNWRKRLERGRLPENVLAWVLRRL
EQRKQAFLFVPHIDELEAVTRLLQRVDARIVGVHAEAPARAEYVQAFRDGSVPLLVTTTILERGVTVPNIDVAVLGAEDR
IFTESALVQIAGRVGRSAAFPDGDVRFFHHGKTTEMVRAHRHIVRMNETAQKRGLLHR
>Mature_457_residues
SVSSPLIASLYGQRIPREQLPFSHADIETALRVGSLHEQSGLIKTPRGWRCVRCGNDERSWFASFPCARCGTNCCYCRKC
LMMGRISSCTRLVHVTMSLPSERYAVPLAWNGTLSAAQEEAAMEVKQAVLNRRELLVWAVCGAGKTEILFPAIAAALEEG
WRVCLATPRIDVVRELAPRFRQAFPRVPLAVWYGGSEERGQIAPLVLSTTHQLLRAYRVFDVMIIDEVDAFPYSVEPMLE
YAVSQARKEQSSLIYLTATPSRAWQLDVQCGKRQAAVIPARYHGHPLPVPSFEWCGNWRKRLERGRLPENVLAWVLRRLE
QRKQAFLFVPHIDELEAVTRLLQRVDARIVGVHAEAPARAEYVQAFRDGSVPLLVTTTILERGVTVPNIDVAVLGAEDRI
FTESALVQIAGRVGRSAAFPDGDVRFFHHGKTTEMVRAHRHIVRMNETAQKRGLLHR

Specific function: Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel [H]

COG id: COG4098

COG function: function code L; Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 51550; Mature: 51419

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS00268 CECROPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSSPLIASLYGQRIPREQLPFSHADIETALRVGSLHEQSGLIKTPRGWRCVRCGNDER
CCCCCHHHHHHHHCCCCHHHCCCCCCHHHHHHHHCCHHHCCCCEECCCCCEEEECCCCCC
SWFASFPCARCGTNCCYCRKCLMMGRISSCTRLVHVTMSLPSERYAVPLAWNGTLSAAQE
CHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEEECCCHHHHHH
EAAMEVKQAVLNRRELLVWAVCGAGKTEILFPAIAAALEEGWRVCLATPRIDVVRELAPR
HHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHH
FRQAFPRVPLAVWYGGSEERGQIAPLVLSTTHQLLRAYRVFDVMIIDEVDAFPYSVEPML
HHHHCCCCCEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHH
EYAVSQARKEQSSLIYLTATPSRAWQLDVQCGKRQAAVIPARYHGHPLPVPSFEWCGNWR
HHHHHHHHHHCCCEEEEEECCCCCEEEECCCCCCCEEEEEHHHCCCCCCCCCHHHHHHHH
KRLERGRLPENVLAWVLRRLEQRKQAFLFVPHIDELEAVTRLLQRVDARIVGVHAEAPAR
HHHHHCCCCHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHCCEEEEEECCCCHH
AEYVQAFRDGSVPLLVTTTILERGVTVPNIDVAVLGAEDRIFTESALVQIAGRVGRSAAF
HHHHHHHHCCCCCEEEEHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCC
PDGDVRFFHHGKTTEMVRAHRHIVRMNETAQKRGLLHR
CCCCEEEEECCCHHHHHHHHHHHHHCCHHHHHCCCCCC
>Mature Secondary Structure 
SVSSPLIASLYGQRIPREQLPFSHADIETALRVGSLHEQSGLIKTPRGWRCVRCGNDER
CCCCHHHHHHHHCCCCHHHCCCCCCHHHHHHHHCCHHHCCCCEECCCCCEEEECCCCCC
SWFASFPCARCGTNCCYCRKCLMMGRISSCTRLVHVTMSLPSERYAVPLAWNGTLSAAQE
CHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEEECCCHHHHHH
EAAMEVKQAVLNRRELLVWAVCGAGKTEILFPAIAAALEEGWRVCLATPRIDVVRELAPR
HHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHH
FRQAFPRVPLAVWYGGSEERGQIAPLVLSTTHQLLRAYRVFDVMIIDEVDAFPYSVEPML
HHHHCCCCCEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHH
EYAVSQARKEQSSLIYLTATPSRAWQLDVQCGKRQAAVIPARYHGHPLPVPSFEWCGNWR
HHHHHHHHHHCCCEEEEEECCCCCEEEECCCCCCCEEEEEHHHCCCCCCCCCHHHHHHHH
KRLERGRLPENVLAWVLRRLEQRKQAFLFVPHIDELEAVTRLLQRVDARIVGVHAEAPAR
HHHHHCCCCHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHCCEEEEEECCCCHH
AEYVQAFRDGSVPLLVTTTILERGVTVPNIDVAVLGAEDRIFTESALVQIAGRVGRSAAF
HHHHHHHHCCCCCEEEEHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCC
PDGDVRFFHHGKTTEMVRAHRHIVRMNETAQKRGLLHR
CCCCEEEEECCCHHHHHHHHHHHHHCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8412657; 9384377 [H]