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The map label for this gene is ald [H]

Identifier: 138896314

GI number: 138896314

Start: 2787567

End: 2788682

Strand: Reverse

Name: ald [H]

Synonym: GTNG_2677

Alternate gene names: 138896314

Gene position: 2788682-2787567 (Counterclockwise)

Preceding gene: 138896315

Following gene: 138896312

Centisome position: 78.55

GC content: 54.93

Gene sequence:

>1116_bases
GTGAAAATTGGCGTTCCAAAAGAAATCAAAAATAATGAAAACCGTGTCGCCATTACACCGGCTGGCGTCATGACGCTTGT
GAAAGCCGGGCATGACGTCTATGTTGAAACGAATGCCGGCGCCGGATCGGGCTTTTCAGATGCCGAATATGAACAAGCCG
GAGCGGTGATCGTACCGAACGCCGAAGACGCGTGGGCGGCGGAGATGGTGTTGAAAGTGAAAGAACCGCTGCCTGAGGAA
TTCCGTTATTTTCGGCCTGGGTTGATTTTGTTTACGTATTTGCATTTGGCAGCGGCCGAAGAGCTAACAAAAGCGCTCGT
TGAACAAAAAGTTGTCGGCATCGCCTATGAGACGGTGCAGTTGGAGAATGGCTCCCTGCCGCTATTAACCCCGATGAGTG
AAGTCGCAGGTCGCATGTCGGTGCAAGTCGGTGCCCAGTTTTTGGAGAAACCGCACGGCGGCAAAGGGATTTTGCTTGGC
GGTGTACCCGGAGTGCGACGCGGCAAAGTGACAATCATCGGTGGCGGAACGGCTGGGACGAACGCAGCAAAAATCGCCGT
CGGCCTCGGGGCGGACGTGACGATTTTGGACATCAACGCCGATCGGCTGCGTGAGTTGGATGATTTGTTTGGCGACCATG
TGACGACGTTAATGTCCAACCCATACCATATCGCGGAATGTGTGCGCGAATCAGATTTGGTCGTCGGCGCGGTCTTGATC
CCGGGGGCGAAAGCGCCAAAGCTCGTTACCGAAGAGATGGTTCGCTCGATGGCCCCGGGCTCGGTACTTGTCGATATTGC
GATCGACCAAGGGGGCATTTTTGAAACAACCGACCGAGTGACGACGCATGACAACCCGACATACGTCAAGCACGGCATCG
TCCATTACGCCGTCGCCAACATGCCGGGCGCTGTCCCGCGCACCTCGACGTTTGCGCTTACGAACGTCACGATCCCATAC
GCCTTGCAGATCGCCAACAAAGGCTACCGCGCTGCGAGTCTTGACAATCCGGCATTGTTAAAAGGAATCAACACGCTAGA
CGGGCACATCGTGTACGAAGCGGTAGCGGCGGCTCACAATATGCCGTATATGGATGTTCATCAGGTATTAGGGTAA

Upstream 100 bases:

>100_bases
TTCCGGTGATCGCAATGCCGTCTTCTTTTGCTGTTTGCTTTCCGGTTGAACAGGGAACAATAAAAGAGGAAGTGGCAAGG
AAAAAGGAGGAAAATGAACG

Downstream 100 bases:

>100_bases
TGAAATGGTGGCGGGGCGCCCAGTGATTCCCGAAGGAGAAGGTGCAAGAAACAAAGCCAATAAACCGCAAAGCTGCCCAA
CTCGGCCTTGCAGCAGGCCG

Product: alanine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MKIGVPKEIKNNENRVAITPAGVMTLVKAGHDVYVETNAGAGSGFSDAEYEQAGAVIVPNAEDAWAAEMVLKVKEPLPEE
FRYFRPGLILFTYLHLAAAEELTKALVEQKVVGIAYETVQLENGSLPLLTPMSEVAGRMSVQVGAQFLEKPHGGKGILLG
GVPGVRRGKVTIIGGGTAGTNAAKIAVGLGADVTILDINADRLRELDDLFGDHVTTLMSNPYHIAECVRESDLVVGAVLI
PGAKAPKLVTEEMVRSMAPGSVLVDIAIDQGGIFETTDRVTTHDNPTYVKHGIVHYAVANMPGAVPRTSTFALTNVTIPY
ALQIANKGYRAASLDNPALLKGINTLDGHIVYEAVAAAHNMPYMDVHQVLG

Sequences:

>Translated_371_residues
MKIGVPKEIKNNENRVAITPAGVMTLVKAGHDVYVETNAGAGSGFSDAEYEQAGAVIVPNAEDAWAAEMVLKVKEPLPEE
FRYFRPGLILFTYLHLAAAEELTKALVEQKVVGIAYETVQLENGSLPLLTPMSEVAGRMSVQVGAQFLEKPHGGKGILLG
GVPGVRRGKVTIIGGGTAGTNAAKIAVGLGADVTILDINADRLRELDDLFGDHVTTLMSNPYHIAECVRESDLVVGAVLI
PGAKAPKLVTEEMVRSMAPGSVLVDIAIDQGGIFETTDRVTTHDNPTYVKHGIVHYAVANMPGAVPRTSTFALTNVTIPY
ALQIANKGYRAASLDNPALLKGINTLDGHIVYEAVAAAHNMPYMDVHQVLG
>Mature_371_residues
MKIGVPKEIKNNENRVAITPAGVMTLVKAGHDVYVETNAGAGSGFSDAEYEQAGAVIVPNAEDAWAAEMVLKVKEPLPEE
FRYFRPGLILFTYLHLAAAEELTKALVEQKVVGIAYETVQLENGSLPLLTPMSEVAGRMSVQVGAQFLEKPHGGKGILLG
GVPGVRRGKVTIIGGGTAGTNAAKIAVGLGADVTILDINADRLRELDDLFGDHVTTLMSNPYHIAECVRESDLVVGAVLI
PGAKAPKLVTEEMVRSMAPGSVLVDIAIDQGGIFETTDRVTTHDNPTYVKHGIVHYAVANMPGAVPRTSTFALTNVTIPY
ALQIANKGYRAASLDNPALLKGINTLDGHIVYEAVAAAHNMPYMDVHQVLG

Specific function: This enzyme is a key factor in the assimilation of L- alanine as an energy source through the tricarboxylic acid cycle during sporulation [H]

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=347, Percent_Identity=32.5648414985591, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI122939153, Length=347, Percent_Identity=32.5648414985591, Blast_Score=145, Evalue=8e-35,
Organism=Escherichia coli, GI1787887, Length=334, Percent_Identity=33.8323353293413, Blast_Score=147, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI17550456, Length=346, Percent_Identity=30.9248554913295, Blast_Score=148, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR008141 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.4.1.1 [H]

Molecular weight: Translated: 39364; Mature: 39364

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00836 ALADH_PNT_1 ; PS00837 ALADH_PNT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGVPKEIKNNENRVAITPAGVMTLVKAGHDVYVETNAGAGSGFSDAEYEQAGAVIVPN
CCCCCCCHHCCCCCEEEECCHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHCCEEEECC
AEDAWAAEMVLKVKEPLPEEFRYFRPGLILFTYLHLAAAEELTKALVEQKVVGIAYETVQ
CCCHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEE
LENGSLPLLTPMSEVAGRMSVQVGAQFLEKPHGGKGILLGGVPGVRRGKVTIIGGGTAGT
ECCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCCCCC
NAAKIAVGLGADVTILDINADRLRELDDLFGDHVTTLMSNPYHIAECVRESDLVVGAVLI
CCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEEEE
PGAKAPKLVTEEMVRSMAPGSVLVDIAIDQGGIFETTDRVTTHDNPTYVKHGIVHYAVAN
CCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCEECCCCEECCCCCCHHHHHHHHHHHHC
MPGAVPRTSTFALTNVTIPYALQIANKGYRAASLDNPALLKGINTLDGHIVYEAVAAAHN
CCCCCCCCCEEEEEEECEEEEEEECCCCCEECCCCCHHHHHCCCCCCCHHHHHHHHHHCC
MPYMDVHQVLG
CCCHHHHHHCC
>Mature Secondary Structure
MKIGVPKEIKNNENRVAITPAGVMTLVKAGHDVYVETNAGAGSGFSDAEYEQAGAVIVPN
CCCCCCCHHCCCCCEEEECCHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHCCEEEECC
AEDAWAAEMVLKVKEPLPEEFRYFRPGLILFTYLHLAAAEELTKALVEQKVVGIAYETVQ
CCCHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEE
LENGSLPLLTPMSEVAGRMSVQVGAQFLEKPHGGKGILLGGVPGVRRGKVTIIGGGTAGT
ECCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCCCCC
NAAKIAVGLGADVTILDINADRLRELDDLFGDHVTTLMSNPYHIAECVRESDLVVGAVLI
CCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEEEE
PGAKAPKLVTEEMVRSMAPGSVLVDIAIDQGGIFETTDRVTTHDNPTYVKHGIVHYAVAN
CCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCEECCCCEECCCCCCHHHHHHHHHHHHC
MPGAVPRTSTFALTNVTIPYALQIANKGYRAASLDNPALLKGINTLDGHIVYEAVAAAHN
CCCCCCCCCEEEEEEECEEEEEEECCCCCEECCCCCHHHHHCCCCCCCHHHHHHHHHHCC
MPYMDVHQVLG
CCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2340274 [H]