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The map label for this gene is phoP [H]

Identifier: 138896293

GI number: 138896293

Start: 2764931

End: 2765635

Strand: Reverse

Name: phoP [H]

Synonym: GTNG_2656

Alternate gene names: 138896293

Gene position: 2765635-2764931 (Counterclockwise)

Preceding gene: 138896294

Following gene: 138896292

Centisome position: 77.9

GC content: 52.48

Gene sequence:

>705_bases
ATGGGCAAAAAAATTTTAGTTGTCGATGACGAGCAGCCGATTGTGACTCTTTTGTCTTACAATTTGGAGAAAGCCGGTTT
TCAAGTCGTAGCCGCCTATGACGGCGAAGAGGCGCTGGAGAAAGTGGCGTTTGAGCAGCCGGCGCTGATCATTTTGGACT
TGATGCTGCCAAAGCTTGACGGTGTCGAAGTATGCAAACGGCTTCGCCAGCAGCAAATCATGACGCCGATTTTAATGTTG
ACGGCACGGGACGATGAATTTGACAAGGTGCTCGGCCTTGAGCTTGGCGCAGATGATTACATGACGAAACCGTTCAGCCC
TCGCGAAGTCGTTGCGCGTGTGAAGGCGATTTTGCGCCGCACGGATCTTGCTCAACCGGCCGCTGAACCGAGCGAACGAC
TTGTCATCGGCGATCTGGAGATTTTCCCAGAGCGTTACGAAGCGGCAGTCGGCGACAAGCCGCTTGAGCTGACGCCGAAA
GAATTTGAGTTGCTCCTTCACTTAGCGCGGCATAAAGGGCGGGTGTTGACGCGCGATCAACTCCTCAGCGCGGTATGGAA
CTACGATTTTGCCGGCGATACACGCATTGTCGATGTCCATATCAGCCATTTGCGCGAGAAAATTGAGGAAGATACGAAAA
AGCCAGTATACATTAAAACGGTGCGCGGTCTCGGCTATAAATTGGAGGAACCGAGGCGGGTATGA

Upstream 100 bases:

>100_bases
CCGACCGTTGGAAGAACAGCCTCTTTCATTTTTTGCCGAGTAAAAGCGTGAGTTATGGTATGATAAAAATGAGAAACATT
GGACGAGATGGAGGCGTGGC

Downstream 100 bases:

>100_bases
ATAGCTTCCGCAACCGGTTGCTGTTTTGGCTCGTAACACTTATTGTCACCGTCTTGATCGCCCTTGGCCTTTTGCTCGGT
CAATTGCTGAAAGACTTTTA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MGKKILVVDDEQPIVTLLSYNLEKAGFQVVAAYDGEEALEKVAFEQPALIILDLMLPKLDGVEVCKRLRQQQIMTPILML
TARDDEFDKVLGLELGADDYMTKPFSPREVVARVKAILRRTDLAQPAAEPSERLVIGDLEIFPERYEAAVGDKPLELTPK
EFELLLHLARHKGRVLTRDQLLSAVWNYDFAGDTRIVDVHISHLREKIEEDTKKPVYIKTVRGLGYKLEEPRRV

Sequences:

>Translated_234_residues
MGKKILVVDDEQPIVTLLSYNLEKAGFQVVAAYDGEEALEKVAFEQPALIILDLMLPKLDGVEVCKRLRQQQIMTPILML
TARDDEFDKVLGLELGADDYMTKPFSPREVVARVKAILRRTDLAQPAAEPSERLVIGDLEIFPERYEAAVGDKPLELTPK
EFELLLHLARHKGRVLTRDQLLSAVWNYDFAGDTRIVDVHISHLREKIEEDTKKPVYIKTVRGLGYKLEEPRRV
>Mature_233_residues
GKKILVVDDEQPIVTLLSYNLEKAGFQVVAAYDGEEALEKVAFEQPALIILDLMLPKLDGVEVCKRLRQQQIMTPILMLT
ARDDEFDKVLGLELGADDYMTKPFSPREVVARVKAILRRTDLAQPAAEPSERLVIGDLEIFPERYEAAVGDKPLELTPKE
FELLLHLARHKGRVLTRDQLLSAVWNYDFAGDTRIVDVHISHLREKIEEDTKKPVYIKTVRGLGYKLEEPRRV

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=42.6086956521739, Blast_Score=176, Evalue=9e-46,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=42.6666666666667, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=43.6123348017621, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=42.1052631578947, Blast_Score=157, Evalue=5e-40,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=41.8502202643172, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=39.4736842105263, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=37.8260869565217, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=36.8888888888889, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=37.3333333333333, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=36.4035087719298, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=34.6320346320346, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=34.5132743362832, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=33.6244541484716, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=32.7586206896552, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=34.1463414634146, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788550, Length=103, Percent_Identity=33.9805825242718, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787487, Length=104, Percent_Identity=34.6153846153846, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=136, Percent_Identity=30.8823529411765, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26660; Mature: 26529

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKKILVVDDEQPIVTLLSYNLEKAGFQVVAAYDGEEALEKVAFEQPALIILDLMLPKLD
CCCEEEEEECCCCEEHHHHHCCCCCCEEEEEEECCHHHHHHHHHCCCHHHHHHHHHCCCC
GVEVCKRLRQQQIMTPILMLTARDDEFDKVLGLELGADDYMTKPFSPREVVARVKAILRR
HHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHCEECCCHHCCCCCCHHHHHHHHHHHHHH
TDLAQPAAEPSERLVIGDLEIFPERYEAAVGDKPLELTPKEFELLLHLARHKGRVLTRDQ
HHCCCCCCCCCCEEEEEHHHHCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEECHHH
LLSAVWNYDFAGDTRIVDVHISHLREKIEEDTKKPVYIKTVRGLGYKLEEPRRV
HHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
GKKILVVDDEQPIVTLLSYNLEKAGFQVVAAYDGEEALEKVAFEQPALIILDLMLPKLD
CCEEEEEECCCCEEHHHHHCCCCCCEEEEEEECCHHHHHHHHHCCCHHHHHHHHHCCCC
GVEVCKRLRQQQIMTPILMLTARDDEFDKVLGLELGADDYMTKPFSPREVVARVKAILRR
HHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHCEECCCHHCCCCCCHHHHHHHHHHHHHH
TDLAQPAAEPSERLVIGDLEIFPERYEAAVGDKPLELTPKEFELLLHLARHKGRVLTRDQ
HHCCCCCCCCCCEEEEEHHHHCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEECHHH
LLSAVWNYDFAGDTRIVDVHISHLREKIEEDTKKPVYIKTVRGLGYKLEEPRRV
HHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]