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The map label for this gene is phoR [H]

Identifier: 138896292

GI number: 138896292

Start: 2763183

End: 2764934

Strand: Reverse

Name: phoR [H]

Synonym: GTNG_2655

Alternate gene names: 138896292

Gene position: 2764934-2763183 (Counterclockwise)

Preceding gene: 138896293

Following gene: 138896291

Centisome position: 77.88

GC content: 51.14

Gene sequence:

>1752_bases
ATGAATAGCTTCCGCAACCGGTTGCTGTTTTGGCTCGTAACACTTATTGTCACCGTCTTGATCGCCCTTGGCCTTTTGCT
CGGTCAATTGCTGAAAGACTTTTATGCTGAGACGATGAACAAACGGATGGAAAAGGAGGCAAAAGCGCTCGCCATTTTGC
TTGAAAACGAACCACTTGAGCGAATTCGCCTCGATTTGAAGGAAATGGGGGATGAGCTGTCGTCGCGCATCACTGTGCTT
GATCGACACCAGCGGTTGCAGTTTGACAGCGGGCGCATCGCGGCGATCAGCGACGAAGACCACGAGCGCATTATCCGCAC
CATTTTGCGTAAAAAGCAGTTCCCTCGCTTTTCGGTGATCGAAAAAGCGAACGATGTGTACTACTATATTGCCCCGTACG
GGCACGGCAGCGAGCGAGGCGGGTATGTCATTTTAAGCACGCCGACGAGTTCGCTGAAAAAAGTGAGTCAGCAAATTTGG
GGGGTGCTCGTGAGCAGCCTCGGCATGGCGCTCATCGTTATTGTCGCTTTGGGCTGGAAAATCGCCAACCAATATATGAG
GCCGATTGAGGCGGCCACAAAAGTGGCGTTTGAGCTCGAAAAAGGCAATTATGCTGCCAGGGTTCCCGATGGCGAGTATA
AAGAAGCCGGCATGCTTGTCCGTTCGATCAACCGGCTTGCCCGCAACTTGCAGGAAATGAGCCGGGCGCGGGAAATCCAA
ACCGACCGGCTCCATACGCTTATCGAAAATGTCGGCAGCGGCTTGTTGTTTATCGACCATCGCGGGCATATCCATTTGAT
CAACCGCGCGTTCCAAACGTATTTTCATCTTGATTCGTCCGATTGCTTGTACCGTCCATATGCCGATGTGTTGCCGCACC
GTGACATCATCAAATTGATCGACGATATTTTTATCACCGAAACGGCGATGCGCCGGCACATGCGGTTGACGATTGGCATT
GAGCGGAAGCATTTTGATGTATACGGCGCTCCGATTATCGGAACGAATGCCGAGTGGAAAGGGATCGTCGTAGTGTTCCA
TGACATTACGGAATTGAAGCGTCTGGAGCAAATTCGCAAAGACTTTGTCGCCAACGTTTCACACGAGCTGAAAACGCCGG
TCACCTCCATTAAAGGGTTTGCCGAGACGCTGCTTGACGGAGCGATGAAAGACGAAGAGGCGTTAGAGCATTTTTTGACG
ATCATTTTAAAGGAAAGCGAGCGGCTGCAAACACTCGTTGAAGAATTGCTTGATTTGTCAAAAATTGAGCAGCACGGATT
TCAATTGCAGCTCGAAGACGTGGACGTGGCCGAAGTGATTGCCGAGGCGGCAGCCGTGTTTCGTCAAAAGGCGGAGGAAA
AGCAAATTGACTTGCGCGTTGAGGCGTTGCCCGGGCTTGTCATCCGCGGCGATCGAAATCGGCTGAAGCAGATTTTGATT
AACTTGCTTGCCAACGCTCTCGCTTATACGCCAGAACATGGACAAGTCGCCGTCGAAGCGGAAGAAAAAGAGAAGGAAGT
GCTCATTCATGTGAAAGATACCGGTATTGGTATCGAGGAGAAGGAAATTCCTCGTATTTTTGAGCGCTTTTATCGCATTG
ACAAAGCGCGCAGTCGTGATTCCGGCGGAACAGGCCTAGGCCTTTCGATCGTCAAACATTTGGTGGAGGCTCATCACGGC
TATATTACAGTAGCAAGCGAAGTGGGGCGCGGCACAGTGTTTACGATCCATTTTCCAAAGCCGGAGCGGTAG

Upstream 100 bases:

>100_bases
TCAGCCATTTGCGCGAGAAAATTGAGGAAGATACGAAAAAGCCAGTATACATTAAAACGGTGCGCGGTCTCGGCTATAAA
TTGGAGGAACCGAGGCGGGT

Downstream 100 bases:

>100_bases
CCGGCTTCTTTTTTATGAGAAGCGGTTTGCATGGTACAATAGAACAAGGAGCGTTCGAGGAGGGATGAGATTGAAGAAAA
AACTCGTCTTAATTGATGGC

Product: sensory box histidine kinase PhoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MNSFRNRLLFWLVTLIVTVLIALGLLLGQLLKDFYAETMNKRMEKEAKALAILLENEPLERIRLDLKEMGDELSSRITVL
DRHQRLQFDSGRIAAISDEDHERIIRTILRKKQFPRFSVIEKANDVYYYIAPYGHGSERGGYVILSTPTSSLKKVSQQIW
GVLVSSLGMALIVIVALGWKIANQYMRPIEAATKVAFELEKGNYAARVPDGEYKEAGMLVRSINRLARNLQEMSRAREIQ
TDRLHTLIENVGSGLLFIDHRGHIHLINRAFQTYFHLDSSDCLYRPYADVLPHRDIIKLIDDIFITETAMRRHMRLTIGI
ERKHFDVYGAPIIGTNAEWKGIVVVFHDITELKRLEQIRKDFVANVSHELKTPVTSIKGFAETLLDGAMKDEEALEHFLT
IILKESERLQTLVEELLDLSKIEQHGFQLQLEDVDVAEVIAEAAAVFRQKAEEKQIDLRVEALPGLVIRGDRNRLKQILI
NLLANALAYTPEHGQVAVEAEEKEKEVLIHVKDTGIGIEEKEIPRIFERFYRIDKARSRDSGGTGLGLSIVKHLVEAHHG
YITVASEVGRGTVFTIHFPKPER

Sequences:

>Translated_583_residues
MNSFRNRLLFWLVTLIVTVLIALGLLLGQLLKDFYAETMNKRMEKEAKALAILLENEPLERIRLDLKEMGDELSSRITVL
DRHQRLQFDSGRIAAISDEDHERIIRTILRKKQFPRFSVIEKANDVYYYIAPYGHGSERGGYVILSTPTSSLKKVSQQIW
GVLVSSLGMALIVIVALGWKIANQYMRPIEAATKVAFELEKGNYAARVPDGEYKEAGMLVRSINRLARNLQEMSRAREIQ
TDRLHTLIENVGSGLLFIDHRGHIHLINRAFQTYFHLDSSDCLYRPYADVLPHRDIIKLIDDIFITETAMRRHMRLTIGI
ERKHFDVYGAPIIGTNAEWKGIVVVFHDITELKRLEQIRKDFVANVSHELKTPVTSIKGFAETLLDGAMKDEEALEHFLT
IILKESERLQTLVEELLDLSKIEQHGFQLQLEDVDVAEVIAEAAAVFRQKAEEKQIDLRVEALPGLVIRGDRNRLKQILI
NLLANALAYTPEHGQVAVEAEEKEKEVLIHVKDTGIGIEEKEIPRIFERFYRIDKARSRDSGGTGLGLSIVKHLVEAHHG
YITVASEVGRGTVFTIHFPKPER
>Mature_583_residues
MNSFRNRLLFWLVTLIVTVLIALGLLLGQLLKDFYAETMNKRMEKEAKALAILLENEPLERIRLDLKEMGDELSSRITVL
DRHQRLQFDSGRIAAISDEDHERIIRTILRKKQFPRFSVIEKANDVYYYIAPYGHGSERGGYVILSTPTSSLKKVSQQIW
GVLVSSLGMALIVIVALGWKIANQYMRPIEAATKVAFELEKGNYAARVPDGEYKEAGMLVRSINRLARNLQEMSRAREIQ
TDRLHTLIENVGSGLLFIDHRGHIHLINRAFQTYFHLDSSDCLYRPYADVLPHRDIIKLIDDIFITETAMRRHMRLTIGI
ERKHFDVYGAPIIGTNAEWKGIVVVFHDITELKRLEQIRKDFVANVSHELKTPVTSIKGFAETLLDGAMKDEEALEHFLT
IILKESERLQTLVEELLDLSKIEQHGFQLQLEDVDVAEVIAEAAAVFRQKAEEKQIDLRVEALPGLVIRGDRNRLKQILI
NLLANALAYTPEHGQVAVEAEEKEKEVLIHVKDTGIGIEEKEIPRIFERFYRIDKARSRDSGGTGLGLSIVKHLVEAHHG
YITVASEVGRGTVFTIHFPKPER

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=251, Percent_Identity=38.6454183266932, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=33.0434782608696, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI48994928, Length=329, Percent_Identity=31.306990881459, Blast_Score=132, Evalue=8e-32,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=35.7758620689655, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788549, Length=392, Percent_Identity=25.5102040816327, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1786783, Length=245, Percent_Identity=31.4285714285714, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI145693157, Length=226, Percent_Identity=31.858407079646, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1788713, Length=363, Percent_Identity=26.7217630853994, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1789149, Length=230, Percent_Identity=31.304347826087, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1790861, Length=206, Percent_Identity=35.4368932038835, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1790346, Length=232, Percent_Identity=30.6034482758621, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI87081816, Length=267, Percent_Identity=27.7153558052434, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=30.1724137931034, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=30, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1787894, Length=262, Percent_Identity=28.2442748091603, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788279, Length=235, Percent_Identity=28.5106382978723, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790300, Length=248, Percent_Identity=30.6451612903226, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1789808, Length=238, Percent_Identity=26.4705882352941, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790551, Length=264, Percent_Identity=27.6515151515151, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789403, Length=200, Percent_Identity=28, Blast_Score=62, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=141, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66513; Mature: 66513

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSFRNRLLFWLVTLIVTVLIALGLLLGQLLKDFYAETMNKRMEKEAKALAILLENEPLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHH
RIRLDLKEMGDELSSRITVLDRHQRLQFDSGRIAAISDEDHERIIRTILRKKQFPRFSVI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCHHHH
EKANDVYYYIAPYGHGSERGGYVILSTPTSSLKKVSQQIWGVLVSSLGMALIVIVALGWK
HCCCCEEEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IANQYMRPIEAATKVAFELEKGNYAARVPDGEYKEAGMLVRSINRLARNLQEMSRAREIQ
HHHHHHHHHHHHHHHHEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDRLHTLIENVGSGLLFIDHRGHIHLINRAFQTYFHLDSSDCLYRPYADVLPHRDIIKLI
HHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHH
DDIFITETAMRRHMRLTIGIERKHFDVYGAPIIGTNAEWKGIVVVFHDITELKRLEQIRK
HHHHHHHHHHHHHEEEEEEEEEEEEEEECCCEECCCCCCCEEEEEEHHHHHHHHHHHHHH
DFVANVSHELKTPVTSIKGFAETLLDGAMKDEEALEHFLTIILKESERLQTLVEELLDLS
HHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KIEQHGFQLQLEDVDVAEVIAEAAAVFRQKAEEKQIDLRVEALPGLVIRGDRNRLKQILI
HHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCEEEECCCCEEEECCHHHHHHHHH
NLLANALAYTPEHGQVAVEAEEKEKEVLIHVKDTGIGIEEKEIPRIFERFYRIDKARSRD
HHHHHHHHCCCCCCCEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCC
SGGTGLGLSIVKHLVEAHHGYITVASEVGRGTVFTIHFPKPER
CCCCCHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCCC
>Mature Secondary Structure
MNSFRNRLLFWLVTLIVTVLIALGLLLGQLLKDFYAETMNKRMEKEAKALAILLENEPLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHH
RIRLDLKEMGDELSSRITVLDRHQRLQFDSGRIAAISDEDHERIIRTILRKKQFPRFSVI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCHHHH
EKANDVYYYIAPYGHGSERGGYVILSTPTSSLKKVSQQIWGVLVSSLGMALIVIVALGWK
HCCCCEEEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IANQYMRPIEAATKVAFELEKGNYAARVPDGEYKEAGMLVRSINRLARNLQEMSRAREIQ
HHHHHHHHHHHHHHHHEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDRLHTLIENVGSGLLFIDHRGHIHLINRAFQTYFHLDSSDCLYRPYADVLPHRDIIKLI
HHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHH
DDIFITETAMRRHMRLTIGIERKHFDVYGAPIIGTNAEWKGIVVVFHDITELKRLEQIRK
HHHHHHHHHHHHHEEEEEEEEEEEEEEECCCEECCCCCCCEEEEEEHHHHHHHHHHHHHH
DFVANVSHELKTPVTSIKGFAETLLDGAMKDEEALEHFLTIILKESERLQTLVEELLDLS
HHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KIEQHGFQLQLEDVDVAEVIAEAAAVFRQKAEEKQIDLRVEALPGLVIRGDRNRLKQILI
HHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCEEEECCCCEEEECCHHHHHHHHH
NLLANALAYTPEHGQVAVEAEEKEKEVLIHVKDTGIGIEEKEIPRIFERFYRIDKARSRD
HHHHHHHHCCCCCCCEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCC
SGGTGLGLSIVKHLVEAHHGYITVASEVGRGTVFTIHFPKPER
CCCCCHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]