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The map label for this gene is pheS [H]

Identifier: 138896270

GI number: 138896270

Start: 2742696

End: 2743730

Strand: Reverse

Name: pheS [H]

Synonym: GTNG_2633

Alternate gene names: 138896270

Gene position: 2743730-2742696 (Counterclockwise)

Preceding gene: 138896271

Following gene: 138896269

Centisome position: 77.28

GC content: 52.46

Gene sequence:

>1035_bases
GTGAAAGAACGGTTGCATGAGCTTGAACGAGAAGCGCTTGAAAAAATTGAACAAGCTGGCGATTTAAAAGCGCTCAACGA
TGTGCGTGTCGCCTATTTAGGCAAAAAAGGGCCGATTACCGAAGTGCTGCGCGGCATGGGAGCATTGCCGCCAGAAGAGC
GTCCGAAAATTGGCGCGCTTGCCAATGAGGTAAGAGAGGCGATCCAAAAGGCGCTCGAAGCAAAACAAACGAAACTGGAA
GAAGAAGAAGTCGAGCGGAAGTTGGCGGCTGAAGCGATCGATGTGACGCTTCCGGGCCGTCCGGTGAAACTGGGGAATCC
TCATCCGCTGACGCGCGTCATCGAGGAAATTGAAGATTTGTTTATCGGCATGGGCTATACGGTCGCCGAAGGTCCGGAAG
TCGAGACCGATTATTACAATTTTGAGGCGCTCAATTTGCCGAAAGGACACCCGGCCCGCGATATGCAAGATTCGTTTTAT
ATTACGGAAGAAATTCTGCTTCGCACCCACACGTCGCCGATGCAGGCACGGACGATGGAAAAACATCGCGGGCGCGGTCC
GGTAAAAATCATTTGCCCGGGGAAAGTGTATCGCCGCGATACCGATGATGCGACCCATTCACATCAGTTTACGCAAATTG
AAGGATTGGTTGTTGACCGCAACATCCGGATGAGCGATTTAAAAGGGACGCTGCGCGAATTTGCCCGCAAGCTGTTCGGT
GAAGGGCGCGACATCCGTTTTCGTCCGAGCTTTTTCCCGTTTACCGAGCCTTCAGTCGAGGTCGATGTGTCCTGCTTCCG
CTGCGAAGGGCACGGCTGCAGCGTTTGCAAAGGTACGGGCTGGATTGAAATTTTAGGCGCTGGCATGGTGCACCCGAACG
TGCTTGAGATGGCCGGCTTTGATTCGAAAACGTATACCGGATTTGCGTTCGGCATGGGGCCGGAGCGGATCGCGATGTTG
AAATACGGCATTGATGACATCCGCCATTTCTATCAGAACGATCTTCGTTTCTTGCAACAATTTTTGCGTGTCTAA

Upstream 100 bases:

>100_bases
GTGCGTCTTCGTTTGCGCTGTTAACAAGGGTGGTACCGCGAGCAACAACTCGTCCCTTATGAGGGACGGGTTTTTTTATT
TTGTTAGAGGAGGGATTGGC

Downstream 100 bases:

>100_bases
AAGAAAAAGGAGGAGTTGGGAATGCTCGTTTCTTATCGTTGGCTAGGCGAATACGTCGATTTGACGGGCGTGACGGCGGA
ACAACTCGCTGATCGCATTA

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKERLHELEREALEKIEQAGDLKALNDVRVAYLGKKGPITEVLRGMGALPPEERPKIGALANEVREAIQKALEAKQTKLE
EEEVERKLAAEAIDVTLPGRPVKLGNPHPLTRVIEEIEDLFIGMGYTVAEGPEVETDYYNFEALNLPKGHPARDMQDSFY
ITEEILLRTHTSPMQARTMEKHRGRGPVKIICPGKVYRRDTDDATHSHQFTQIEGLVVDRNIRMSDLKGTLREFARKLFG
EGRDIRFRPSFFPFTEPSVEVDVSCFRCEGHGCSVCKGTGWIEILGAGMVHPNVLEMAGFDSKTYTGFAFGMGPERIAML
KYGIDDIRHFYQNDLRFLQQFLRV

Sequences:

>Translated_344_residues
MKERLHELEREALEKIEQAGDLKALNDVRVAYLGKKGPITEVLRGMGALPPEERPKIGALANEVREAIQKALEAKQTKLE
EEEVERKLAAEAIDVTLPGRPVKLGNPHPLTRVIEEIEDLFIGMGYTVAEGPEVETDYYNFEALNLPKGHPARDMQDSFY
ITEEILLRTHTSPMQARTMEKHRGRGPVKIICPGKVYRRDTDDATHSHQFTQIEGLVVDRNIRMSDLKGTLREFARKLFG
EGRDIRFRPSFFPFTEPSVEVDVSCFRCEGHGCSVCKGTGWIEILGAGMVHPNVLEMAGFDSKTYTGFAFGMGPERIAML
KYGIDDIRHFYQNDLRFLQQFLRV
>Mature_344_residues
MKERLHELEREALEKIEQAGDLKALNDVRVAYLGKKGPITEVLRGMGALPPEERPKIGALANEVREAIQKALEAKQTKLE
EEEVERKLAAEAIDVTLPGRPVKLGNPHPLTRVIEEIEDLFIGMGYTVAEGPEVETDYYNFEALNLPKGHPARDMQDSFY
ITEEILLRTHTSPMQARTMEKHRGRGPVKIICPGKVYRRDTDDATHSHQFTQIEGLVVDRNIRMSDLKGTLREFARKLFG
EGRDIRFRPSFFPFTEPSVEVDVSCFRCEGHGCSVCKGTGWIEILGAGMVHPNVLEMAGFDSKTYTGFAFGMGPERIAML
KYGIDDIRHFYQNDLRFLQQFLRV

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758340, Length=270, Percent_Identity=31.8518518518519, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI5729820, Length=291, Percent_Identity=29.8969072164948, Blast_Score=119, Evalue=4e-27,
Organism=Escherichia coli, GI1788007, Length=337, Percent_Identity=52.5222551928783, Blast_Score=355, Evalue=2e-99,
Organism=Caenorhabditis elegans, GI17508957, Length=270, Percent_Identity=30, Blast_Score=134, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI32563657, Length=270, Percent_Identity=30, Blast_Score=134, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI32566635, Length=258, Percent_Identity=32.9457364341085, Blast_Score=120, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6321087, Length=351, Percent_Identity=28.2051282051282, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6325304, Length=327, Percent_Identity=27.217125382263, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI18858079, Length=286, Percent_Identity=31.1188811188811, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI17137424, Length=295, Percent_Identity=27.1186440677966, Blast_Score=101, Evalue=7e-22,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 39020; Mature: 39020

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERLHELEREALEKIEQAGDLKALNDVRVAYLGKKGPITEVLRGMGALPPEERPKIGAL
CHHHHHHHHHHHHHHHHHCCCCHHHCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCHHHH
ANEVREAIQKALEAKQTKLEEEEVERKLAAEAIDVTLPGRPVKLGNPHPLTRVIEEIEDL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEECCCCCEECCCCCHHHHHHHHHHHH
FIGMGYTVAEGPEVETDYYNFEALNLPKGHPARDMQDSFYITEEILLRTHTSPMQARTME
HHCCCCEECCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
KHRGRGPVKIICPGKVYRRDTDDATHSHQFTQIEGLVVDRNIRMSDLKGTLREFARKLFG
HHCCCCCEEEEECCHHCCCCCCCCCCCCCHHEEEEEEEECCCCHHHHHHHHHHHHHHHHC
EGRDIRFRPSFFPFTEPSVEVDVSCFRCEGHGCSVCKGTGWIEILGAGMVHPNVLEMAGF
CCCCEEECCCCCCCCCCCCEEEEEEEEECCCCCCEECCCCEEEEEECCCCCCCHHHHCCC
DSKTYTGFAFGMGPERIAMLKYGIDDIRHFYQNDLRFLQQFLRV
CCCCCCEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKERLHELEREALEKIEQAGDLKALNDVRVAYLGKKGPITEVLRGMGALPPEERPKIGAL
CHHHHHHHHHHHHHHHHHCCCCHHHCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCHHHH
ANEVREAIQKALEAKQTKLEEEEVERKLAAEAIDVTLPGRPVKLGNPHPLTRVIEEIEDL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEECCCCCEECCCCCHHHHHHHHHHHH
FIGMGYTVAEGPEVETDYYNFEALNLPKGHPARDMQDSFYITEEILLRTHTSPMQARTME
HHCCCCEECCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
KHRGRGPVKIICPGKVYRRDTDDATHSHQFTQIEGLVVDRNIRMSDLKGTLREFARKLFG
HHCCCCCEEEEECCHHCCCCCCCCCCCCCHHEEEEEEEECCCCHHHHHHHHHHHHHHHHC
EGRDIRFRPSFFPFTEPSVEVDVSCFRCEGHGCSVCKGTGWIEILGAGMVHPNVLEMAGF
CCCCEEECCCCCCCCCCCCEEEEEEEEECCCCCCEECCCCEEEEEECCCCCCCHHHHCCC
DSKTYTGFAFGMGPERIAMLKYGIDDIRHFYQNDLRFLQQFLRV
CCCCCCEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA