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The map label for this gene is bglH [H]

Identifier: 138895907

GI number: 138895907

Start: 2380777

End: 2382144

Strand: Reverse

Name: bglH [H]

Synonym: GTNG_2266

Alternate gene names: 138895907

Gene position: 2382144-2380777 (Counterclockwise)

Preceding gene: 138895908

Following gene: 138895904

Centisome position: 67.1

GC content: 51.97

Gene sequence:

>1368_bases
GTGCCATCACAACGCCAATCGATCATCCCCGACAACTTTTTATGGGGCGGGGCAGTGACGTCGTTCCAAACGGAAGGGGC
ATGGAATGAAGATGGAAAAGGGCTATCGATCGTCGATGCGCGCCCAATTCCAGAAGGCCATTCCGATTGGAAAGTGGCAG
TCGACTTTTACCATCGCTATAAAGAAGATATTGCCTTGTTTAAAGAGTTGGGCTTCACCGCCTATCGAACGAGCATTGCT
TGGACGCGCATTTTTCCGGACGGGGAAGGGGAGCCGAATGAAGCGGGCTTGGCGTTTTATGACGCCGTGTTTGACGAATT
GAGAGCAAACGGCATCGAACCGGTCATTACGCTGTACCATTTTGATTTGCCGCTGGCGTTGGCGAAAAAGTATAACGGCT
TTGCCTCACGGAAGGTCGTCGATTTGTTTGAACGATACGCACGCACCGTATTCGAGCGTTACCGCGGGAAAGTGAACTAT
TGGCTGACGTTCAATGAACAAAACCTAGTGCTGGAAAACCCGCATTTATGGGGGGCGATCTGTCCAGATGATGAAGACCC
GGAAGCGTTTGCCTACCGCGTCTGCCATCATGTTTTTATCGCCCACGCCAAGGCGGTGAAGGCGCTGCGCGAGATCGCAC
CAGAGGCAAAAATTGGTGGGATGGTGACGTATTTGACGACATATCCGGCTACATGCCAGCCGGAAGATGCCTTGGCCAAT
GTGCAGGCAAAAGAGCTGCTCAGCGATTTCTTTTTTGATATGTTCGCCCGTGGCGCCTATCCGCGCTATGTGACCAACCG
GCTCGAGAAAAAGGGGATTCGCTTGCCGCTCGAAGCGGACGATGAGGAACTGCTGCGCACGCAGACAGTTGACTTTTTGT
CGTTCAGCTATTACCAAAGCCAAATCGTCCGCCATCAAGAATATGACGAGCGAATCATCAGAGGGCTTGAGCCGAACCCT
CACTTGCCGAAGACGAAATGGGGATGGGCGATCGATCCGATCGGCTTGCGCCTTGCGTTGAAAGATGTGTACGCTCGCTA
CCAGATGCCGATTTTCATCACCGAAAACGGGATCGGGTTGGAAGAGGAGCTGAATGAGAACGGCACGGTTGAAGATGACG
AGCGAATCGACTACTTGCGCCGCCATATCGAGCAAATGAAGATGGCGATGGAAGAAGGAGTCGAGGTGATCGGCTATTTA
ATGTGGGGGGCAACCGATTTGTTGAGCTCGCAAGGAGAGATGCGCAAACGGTACGGCGTCATTTTCGTCAATCGCGATGA
CCAAAACTTGCGTGATTTAAAGCGCTATAAGAAAAAAAGCTTTTACTGGTTCCAACGCGTCATTCGCACGAACGGGGAGG
AATTGTAA

Upstream 100 bases:

>100_bases
AAGAGAATTTTTAGATGAAATCATAGTGGGTGGGCGGCCAGGCGAATGGTTATGAGTTGGGAAGCAAGCATGAAAACTTA
CATAGCAGGAGGGAGATTAA

Downstream 100 bases:

>100_bases
AACAAAAACAAGCTTCAGAAGAGGCGGAGAAACCCCGCCCCTTTTTATCAGTTCTTTGGACGCCGGTGGCGAATGTCTCA
TCGTGGAAAATGGTTGTCTC

Product: beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MPSQRQSIIPDNFLWGGAVTSFQTEGAWNEDGKGLSIVDARPIPEGHSDWKVAVDFYHRYKEDIALFKELGFTAYRTSIA
WTRIFPDGEGEPNEAGLAFYDAVFDELRANGIEPVITLYHFDLPLALAKKYNGFASRKVVDLFERYARTVFERYRGKVNY
WLTFNEQNLVLENPHLWGAICPDDEDPEAFAYRVCHHVFIAHAKAVKALREIAPEAKIGGMVTYLTTYPATCQPEDALAN
VQAKELLSDFFFDMFARGAYPRYVTNRLEKKGIRLPLEADDEELLRTQTVDFLSFSYYQSQIVRHQEYDERIIRGLEPNP
HLPKTKWGWAIDPIGLRLALKDVYARYQMPIFITENGIGLEEELNENGTVEDDERIDYLRRHIEQMKMAMEEGVEVIGYL
MWGATDLLSSQGEMRKRYGVIFVNRDDQNLRDLKRYKKKSFYWFQRVIRTNGEEL

Sequences:

>Translated_455_residues
MPSQRQSIIPDNFLWGGAVTSFQTEGAWNEDGKGLSIVDARPIPEGHSDWKVAVDFYHRYKEDIALFKELGFTAYRTSIA
WTRIFPDGEGEPNEAGLAFYDAVFDELRANGIEPVITLYHFDLPLALAKKYNGFASRKVVDLFERYARTVFERYRGKVNY
WLTFNEQNLVLENPHLWGAICPDDEDPEAFAYRVCHHVFIAHAKAVKALREIAPEAKIGGMVTYLTTYPATCQPEDALAN
VQAKELLSDFFFDMFARGAYPRYVTNRLEKKGIRLPLEADDEELLRTQTVDFLSFSYYQSQIVRHQEYDERIIRGLEPNP
HLPKTKWGWAIDPIGLRLALKDVYARYQMPIFITENGIGLEEELNENGTVEDDERIDYLRRHIEQMKMAMEEGVEVIGYL
MWGATDLLSSQGEMRKRYGVIFVNRDDQNLRDLKRYKKKSFYWFQRVIRTNGEEL
>Mature_454_residues
PSQRQSIIPDNFLWGGAVTSFQTEGAWNEDGKGLSIVDARPIPEGHSDWKVAVDFYHRYKEDIALFKELGFTAYRTSIAW
TRIFPDGEGEPNEAGLAFYDAVFDELRANGIEPVITLYHFDLPLALAKKYNGFASRKVVDLFERYARTVFERYRGKVNYW
LTFNEQNLVLENPHLWGAICPDDEDPEAFAYRVCHHVFIAHAKAVKALREIAPEAKIGGMVTYLTTYPATCQPEDALANV
QAKELLSDFFFDMFARGAYPRYVTNRLEKKGIRLPLEADDEELLRTQTVDFLSFSYYQSQIVRHQEYDERIIRGLEPNPH
LPKTKWGWAIDPIGLRLALKDVYARYQMPIFITENGIGLEEELNENGTVEDDERIDYLRRHIEQMKMAMEEGVEVIGYLM
WGATDLLSSQGEMRKRYGVIFVNRDDQNLRDLKRYKKKSFYWFQRVIRTNGEEL

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=473, Percent_Identity=31.5010570824524, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI110681710, Length=472, Percent_Identity=28.8135593220339, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI13273313, Length=475, Percent_Identity=28, Blast_Score=191, Evalue=9e-49,
Organism=Homo sapiens, GI24497614, Length=477, Percent_Identity=29.3501048218029, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI28376633, Length=460, Percent_Identity=28.2608695652174, Blast_Score=161, Evalue=1e-39,
Organism=Escherichia coli, GI2367270, Length=462, Percent_Identity=47.6190476190476, Blast_Score=427, Evalue=1e-121,
Organism=Escherichia coli, GI2367174, Length=483, Percent_Identity=46.1697722567288, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI1789070, Length=477, Percent_Identity=43.8155136268344, Blast_Score=409, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17539390, Length=475, Percent_Identity=31.1578947368421, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17552856, Length=474, Percent_Identity=29.3248945147679, Blast_Score=185, Evalue=5e-47,
Organism=Drosophila melanogaster, GI21356577, Length=489, Percent_Identity=30.0613496932515, Blast_Score=185, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 52872; Mature: 52741

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSQRQSIIPDNFLWGGAVTSFQTEGAWNEDGKGLSIVDARPIPEGHSDWKVAVDFYHRY
CCCCCCCCCCCCCEECCCCCCEECCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
KEDIALFKELGFTAYRTSIAWTRIFPDGEGEPNEAGLAFYDAVFDELRANGIEPVITLYH
HHHHHHHHHHCCHHHHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEE
FDLPLALAKKYNGFASRKVVDLFERYARTVFERYRGKVNYWLTFNEQNLVLENPHLWGAI
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCEEEEE
CPDDEDPEAFAYRVCHHVFIAHAKAVKALREIAPEAKIGGMVTYLTTYPATCQPEDALAN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEEECCCCCCCCHHHHHC
VQAKELLSDFFFDMFARGAYPRYVTNRLEKKGIRLPLEADDEELLRTQTVDFLSFSYYQS
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QIVRHQEYDERIIRGLEPNPHLPKTKWGWAIDPIGLRLALKDVYARYQMPIFITENGIGL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHCCCEEEECCCCCC
EEELNENGTVEDDERIDYLRRHIEQMKMAMEEGVEVIGYLMWGATDLLSSQGEMRKRYGV
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCE
IFVNRDDQNLRDLKRYKKKSFYWFQRVIRTNGEEL
EEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PSQRQSIIPDNFLWGGAVTSFQTEGAWNEDGKGLSIVDARPIPEGHSDWKVAVDFYHRY
CCCCCCCCCCCCEECCCCCCEECCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
KEDIALFKELGFTAYRTSIAWTRIFPDGEGEPNEAGLAFYDAVFDELRANGIEPVITLYH
HHHHHHHHHHCCHHHHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEE
FDLPLALAKKYNGFASRKVVDLFERYARTVFERYRGKVNYWLTFNEQNLVLENPHLWGAI
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCEEEEE
CPDDEDPEAFAYRVCHHVFIAHAKAVKALREIAPEAKIGGMVTYLTTYPATCQPEDALAN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEEECCCCCCCCHHHHHC
VQAKELLSDFFFDMFARGAYPRYVTNRLEKKGIRLPLEADDEELLRTQTVDFLSFSYYQS
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QIVRHQEYDERIIRGLEPNPHLPKTKWGWAIDPIGLRLALKDVYARYQMPIFITENGIGL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHCCCEEEECCCCCC
EEELNENGTVEDDERIDYLRRHIEQMKMAMEEGVEVIGYLMWGATDLLSSQGEMRKRYGV
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCE
IFVNRDDQNLRDLKRYKKKSFYWFQRVIRTNGEEL
EEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883710; 7704263; 9384377 [H]