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The map label for this gene is resA [H]

Identifier: 138895851

GI number: 138895851

Start: 2335587

End: 2336111

Strand: Reverse

Name: resA [H]

Synonym: GTNG_2210

Alternate gene names: 138895851

Gene position: 2336111-2335587 (Counterclockwise)

Preceding gene: 138895852

Following gene: 138895850

Centisome position: 65.8

GC content: 45.9

Gene sequence:

>525_bases
ATGAAAAAACAACAGCGCTTAGTGATGAGAACAGTCATTTTGCTCTTGCTGTTGGCCGCACTCGGTTATACGATTTACGC
CAACTTTTTCACTGAGAAAACGGCGGTCGCTGTCGGTTCAACAGCGCCCGATTTTGTGCTGTCTGACCTTGAAGGGCGTG
AACATCGCCTCACAGACTATCGAGGCAAAGGCGTCTTTTTAAACTTTTGGGGAACGTGGTGCAAACCGTGCGAACGGGAA
ATGCCGTACATGAACGAGTTGTACCCGATTTATCAAAAGCAAGGAGTCGAAATTTTAGCTGTCAATGTCGGTGAGCCGAA
GCTAAATGTCGAAAAGTTTGCAGAACGGTTCGGATTAACGTTTCCAATCGTCATCGACCGCCAAGATCAAGTGTTGAACG
CATATGGCGTCGGGCCGCTGCCGACGACGTTTTTGATTGACAAAAACGGTAAAGTGAAAAAAATCATTACCGGCACAATG
ACAAAAGAAGATATTAAGCAGCATCTAGAAAGCATTAAACCGTGA

Upstream 100 bases:

>100_bases
ATAGACTTTGCTATAATGGAAAATGGAAGATTATGAACTGTCACGTAAACCCCCTACGGCATCGACCGTAAGGGGGTGAG
AAACTGAAGGAGTTTGAGCG

Downstream 100 bases:

>100_bases
GGAGTTTTGCGCCATGGAACAAGTGAAATGTGAATGCGGCCACGTTAACCCGCACGGCACGGTGTTTTGCGAATCGTGCG
GTAAGCCGCTTGAGGAACAG

Product: thiol-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MKKQQRLVMRTVILLLLLAALGYTIYANFFTEKTAVAVGSTAPDFVLSDLEGREHRLTDYRGKGVFLNFWGTWCKPCERE
MPYMNELYPIYQKQGVEILAVNVGEPKLNVEKFAERFGLTFPIVIDRQDQVLNAYGVGPLPTTFLIDKNGKVKKIITGTM
TKEDIKQHLESIKP

Sequences:

>Translated_174_residues
MKKQQRLVMRTVILLLLLAALGYTIYANFFTEKTAVAVGSTAPDFVLSDLEGREHRLTDYRGKGVFLNFWGTWCKPCERE
MPYMNELYPIYQKQGVEILAVNVGEPKLNVEKFAERFGLTFPIVIDRQDQVLNAYGVGPLPTTFLIDKNGKVKKIITGTM
TKEDIKQHLESIKP
>Mature_174_residues
MKKQQRLVMRTVILLLLLAALGYTIYANFFTEKTAVAVGSTAPDFVLSDLEGREHRLTDYRGKGVFLNFWGTWCKPCERE
MPYMNELYPIYQKQGVEILAVNVGEPKLNVEKFAERFGLTFPIVIDRQDQVLNAYGVGPLPTTFLIDKNGKVKKIITGTM
TKEDIKQHLESIKP

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=182, Percent_Identity=28.021978021978, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 19831; Mature: 19831

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQQRLVMRTVILLLLLAALGYTIYANFFTEKTAVAVGSTAPDFVLSDLEGREHRLTDY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHCCCCCCCCCCCC
RGKGVFLNFWGTWCKPCEREMPYMNELYPIYQKQGVEILAVNVGEPKLNVEKFAERFGLT
CCCEEEEECCCCCCCCHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCE
FPIVIDRQDQVLNAYGVGPLPTTFLIDKNGKVKKIITGTMTKEDIKQHLESIKP
EEEEECCCCHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKKQQRLVMRTVILLLLLAALGYTIYANFFTEKTAVAVGSTAPDFVLSDLEGREHRLTDY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHCCCCCCCCCCCC
RGKGVFLNFWGTWCKPCEREMPYMNELYPIYQKQGVEILAVNVGEPKLNVEKFAERFGLT
CCCEEEEECCCCCCCCHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCE
FPIVIDRQDQVLNAYGVGPLPTTFLIDKNGKVKKIITGTMTKEDIKQHLESIKP
EEEEECCCCHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA