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The map label for this gene is hisK [H]

Identifier: 138895826

GI number: 138895826

Start: 2310852

End: 2311706

Strand: Reverse

Name: hisK [H]

Synonym: GTNG_2185

Alternate gene names: 138895826

Gene position: 2311706-2310852 (Counterclockwise)

Preceding gene: 138895827

Following gene: 138895823

Centisome position: 65.11

GC content: 47.72

Gene sequence:

>855_bases
ATGCGTTATAATGAGAAAAACATCAGGAGAGGAGAAAGACAGATGTTGACCGACTACCATAACCATCTTGAACGGGGGAC
ATTGACGCTTGATTATTTGCGTCAATTTACGGATGAGGCGGCGAAAAAAGGGATTGAGCATTTCGGCATTTCCGAACACG
CGTATCATTTTTATCAAACAAAAAACATTTTGTCCAATCCGTGGGTGGAAGCGCGCCGCTGCTACGATATGGCTGATTAT
GTCCAGCTGTTCCATGAAGCGTGGGATGCCGGCATCGATGTGAAAATGTCCATCGAAATGGACTATACGCCAGGCAAGCA
TGAAGAGATGGCGGCGTTCATCCGCTCGTACGATTTTGACTATGTCATCGGCTCCATCCATTGGGTCGACGACTTTGGCA
TTGACTTAGTCGAATATCGCCGCGAGTGGGAACGTCGTGATTTGTACGATACATACCGCAAATATTTTGATCAAGTCGTG
ACGCTTGCTGAATCGAACTTATTTGATATTATCGGTCACCTCGATTTGGTGAAAATTTTTAAATATGTTCCGGAAGATGA
AGAATTTTTGCTCGAGCAATATGACCGGGCGACAACGGCGCTCGCTAATTCAAAAACATGCGTTGAGATCAGCACGGCCG
GGCTGCGTAAGCCGGTCGGTGAGCTGTACCCGGATCCACGCTTGCTAAAAATGTGCTATGAAAAAGGCATTCCAATCGTC
TTCTCCTCTGACGCGCACGTGCCGGAACATGTCGGTGCCGACTTTGATAAGGCAATTGAACTTGCCCGCAGCGTTGGTTA
TACTGAGTTGATGACGTTCTCGAAAGGAGAACGGAAGGCAGTGCCGCTCGGTTGA

Upstream 100 bases:

>100_bases
CGGTTGCGGGTGTGGCAGTATGCGTCGGTCTGTTGTTTCTCGTCGGTGCCAACGGATGATTGGATGAATATTCGAAAAAC
GGTTGTCCTCTTTCGCGGTG

Downstream 100 bases:

>100_bases
ACGGAATGATACGATGAAAAAACATGCAGGTTTCCAATCCTGGGAGCCTGCATGTTTTATGGCCGGACGGGATGGATTGT
GGCGTGATGCAAGAGAAATT

Product: PHP family histidinol phosphatase/hydrolase

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MRYNEKNIRRGERQMLTDYHNHLERGTLTLDYLRQFTDEAAKKGIEHFGISEHAYHFYQTKNILSNPWVEARRCYDMADY
VQLFHEAWDAGIDVKMSIEMDYTPGKHEEMAAFIRSYDFDYVIGSIHWVDDFGIDLVEYRREWERRDLYDTYRKYFDQVV
TLAESNLFDIIGHLDLVKIFKYVPEDEEFLLEQYDRATTALANSKTCVEISTAGLRKPVGELYPDPRLLKMCYEKGIPIV
FSSDAHVPEHVGADFDKAIELARSVGYTELMTFSKGERKAVPLG

Sequences:

>Translated_284_residues
MRYNEKNIRRGERQMLTDYHNHLERGTLTLDYLRQFTDEAAKKGIEHFGISEHAYHFYQTKNILSNPWVEARRCYDMADY
VQLFHEAWDAGIDVKMSIEMDYTPGKHEEMAAFIRSYDFDYVIGSIHWVDDFGIDLVEYRREWERRDLYDTYRKYFDQVV
TLAESNLFDIIGHLDLVKIFKYVPEDEEFLLEQYDRATTALANSKTCVEISTAGLRKPVGELYPDPRLLKMCYEKGIPIV
FSSDAHVPEHVGADFDKAIELARSVGYTELMTFSKGERKAVPLG
>Mature_284_residues
MRYNEKNIRRGERQMLTDYHNHLERGTLTLDYLRQFTDEAAKKGIEHFGISEHAYHFYQTKNILSNPWVEARRCYDMADY
VQLFHEAWDAGIDVKMSIEMDYTPGKHEEMAAFIRSYDFDYVIGSIHWVDDFGIDLVEYRREWERRDLYDTYRKYFDQVV
TLAESNLFDIIGHLDLVKIFKYVPEDEEFLLEQYDRATTALANSKTCVEISTAGLRKPVGELYPDPRLLKMCYEKGIPIV
FSSDAHVPEHVGADFDKAIELARSVGYTELMTFSKGERKAVPLG

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 33306; Mature: 33306

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYNEKNIRRGERQMLTDYHNHLERGTLTLDYLRQFTDEAAKKGIEHFGISEHAYHFYQT
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KNILSNPWVEARRCYDMADYVQLFHEAWDAGIDVKMSIEMDYTPGKHEEMAAFIRSYDFD
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCC
YVIGSIHWVDDFGIDLVEYRREWERRDLYDTYRKYFDQVVTLAESNLFDIIGHLDLVKIF
EEEEEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYVPEDEEFLLEQYDRATTALANSKTCVEISTAGLRKPVGELYPDPRLLKMCYEKGIPIV
HHCCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHCCHHHHCCCHHHHHHHHHCCCCEE
FSSDAHVPEHVGADFDKAIELARSVGYTELMTFSKGERKAVPLG
ECCCCCCHHHHCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRYNEKNIRRGERQMLTDYHNHLERGTLTLDYLRQFTDEAAKKGIEHFGISEHAYHFYQT
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KNILSNPWVEARRCYDMADYVQLFHEAWDAGIDVKMSIEMDYTPGKHEEMAAFIRSYDFD
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCC
YVIGSIHWVDDFGIDLVEYRREWERRDLYDTYRKYFDQVVTLAESNLFDIIGHLDLVKIF
EEEEEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYVPEDEEFLLEQYDRATTALANSKTCVEISTAGLRKPVGELYPDPRLLKMCYEKGIPIV
HHCCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHCCHHHHCCCHHHHHHHHHCCCCEE
FSSDAHVPEHVGADFDKAIELARSVGYTELMTFSKGERKAVPLG
ECCCCCCHHHHCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]