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The map label for this gene is mecA2 [H]

Identifier: 138895813

GI number: 138895813

Start: 2300379

End: 2301272

Strand: Reverse

Name: mecA2 [H]

Synonym: GTNG_2172

Alternate gene names: 138895813

Gene position: 2301272-2300379 (Counterclockwise)

Preceding gene: 138895814

Following gene: 138895812

Centisome position: 64.82

GC content: 48.66

Gene sequence:

>894_bases
ATGGTGGACAAATTCGGCTGTTTTCGTTTGGGTTGTATGAAAAAGGAGGGCTCAAATGGCACGGCAACACGGCGTTGTTC
ACGAGTAACGGCTACGGGACGACCGGGGTGCCGCTTCGCCTTGGGGCGCCGGCAGAAACCCATCTCATCAAAATTGTGCC
TGGGAAACTGGCAACCGAGAAAAAATGCTTGTCTAAAACCGGGAAAACGATGTAAACTCATTAATAATAACAAACGAACC
AATTGCGAGTTGCAACATACAATAACGGTAAGAGATGGCTCTGTAGGTAAGGAGGGGTTGCCGATGCGTCTTGAGCGCTT
GACCCACAATAAAATAAAAATCTTTTTGACGTTTGACGATTTGCTGGACCGCGGATTGACAAAAGACGATTTGTGGAGAG
ACACGTTTAAAGTGCATCAGCTGTTCCGAGATATGATTGAGGAAGCAAGCGAAGAGCTCGGCTTCGAAGTGAACGGATCG
ATCGCGGTCGAAGTTTACTCTTTACCGGCACAGGGCATGGTCGTTATCGTTACGAATGAGGGCGACTACAACGACATCGA
AGAAGAATTTGCGGACGATTACATTGAAATGCAAGTAACGCTCGATGAGAGCGATGACATATTTTACGAATTTCAAACGT
TCGAAGATGTCATTCAGCTCGCCCATCGTTTGTGTGCGGTCGGCTGCCTCGACGGCACGCTCTATTCGTACCAGGGCCGC
TTTTACTTGCATGTTGCCGAAGAACCACCGATTCCGCTCGACAATTTTGTCGCCTTGCTGGCCGAGTTCGGCAACCCGGC
TACGATAACGATACACCGTGTGCAAGAATATGGGAAACGATTAATGGAACGCCGCGCCATTGAGCAACTCGTTCATTATT
TCCGGGCTAACTAA

Upstream 100 bases:

>100_bases
CCGCCTGAATCATTTCGCATTTTAGCCTGTCATAATCCGGCAATCATTGCTCGTCTCGAAGATGAGCAACATATTTCGCT
CGTGTTGAGCGGCCATACAC

Downstream 100 bases:

>100_bases
GCACGACTAGACTCCTGTATATGGACAAGGAGTCTATTTTTTCGCAGGAAACAATGTTTGGAATGTTTGGTCCGTTTCAG
CCTTTTTTCCTTTGCATCCG

Product: adaptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MVDKFGCFRLGCMKKEGSNGTATRRCSRVTATGRPGCRFALGRRQKPISSKLCLGNWQPRKNACLKPGKRCKLINNNKRT
NCELQHTITVRDGSVGKEGLPMRLERLTHNKIKIFLTFDDLLDRGLTKDDLWRDTFKVHQLFRDMIEEASEELGFEVNGS
IAVEVYSLPAQGMVVIVTNEGDYNDIEEEFADDYIEMQVTLDESDDIFYEFQTFEDVIQLAHRLCAVGCLDGTLYSYQGR
FYLHVAEEPPIPLDNFVALLAEFGNPATITIHRVQEYGKRLMERRAIEQLVHYFRAN

Sequences:

>Translated_297_residues
MVDKFGCFRLGCMKKEGSNGTATRRCSRVTATGRPGCRFALGRRQKPISSKLCLGNWQPRKNACLKPGKRCKLINNNKRT
NCELQHTITVRDGSVGKEGLPMRLERLTHNKIKIFLTFDDLLDRGLTKDDLWRDTFKVHQLFRDMIEEASEELGFEVNGS
IAVEVYSLPAQGMVVIVTNEGDYNDIEEEFADDYIEMQVTLDESDDIFYEFQTFEDVIQLAHRLCAVGCLDGTLYSYQGR
FYLHVAEEPPIPLDNFVALLAEFGNPATITIHRVQEYGKRLMERRAIEQLVHYFRAN
>Mature_297_residues
MVDKFGCFRLGCMKKEGSNGTATRRCSRVTATGRPGCRFALGRRQKPISSKLCLGNWQPRKNACLKPGKRCKLINNNKRT
NCELQHTITVRDGSVGKEGLPMRLERLTHNKIKIFLTFDDLLDRGLTKDDLWRDTFKVHQLFRDMIEEASEELGFEVNGS
IAVEVYSLPAQGMVVIVTNEGDYNDIEEEFADDYIEMQVTLDESDDIFYEFQTFEDVIQLAHRLCAVGCLDGTLYSYQGR
FYLHVAEEPPIPLDNFVALLAEFGNPATITIHRVQEYGKRLMERRAIEQLVHYFRAN

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When ove

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008681 [H]

Pfam domain/function: PF05389 MecA [H]

EC number: NA

Molecular weight: Translated: 34045; Mature: 34045

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDKFGCFRLGCMKKEGSNGTATRRCSRVTATGRPGCRFALGRRQKPISSKLCLGNWQPR
CCCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCCEECCCCCCCCCCCCEECCCCCCC
KNACLKPGKRCKLINNNKRTNCELQHTITVRDGSVGKEGLPMRLERLTHNKIKIFLTFDD
CCCCCCCCCEEEEECCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHCCCCEEEEEEEEHH
LLDRGLTKDDLWRDTFKVHQLFRDMIEEASEELGFEVNGSIAVEVYSLPAQGMVVIVTNE
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCEEEEEEEECCCCCEEEEEECC
GDYNDIEEEFADDYIEMQVTLDESDDIFYEFQTFEDVIQLAHRLCAVGCLDGTLYSYQGR
CCCCHHHHHHCCCEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCE
FYLHVAEEPPIPLDNFVALLAEFGNPATITIHRVQEYGKRLMERRAIEQLVHYFRAN
EEEEECCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVDKFGCFRLGCMKKEGSNGTATRRCSRVTATGRPGCRFALGRRQKPISSKLCLGNWQPR
CCCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCCEECCCCCCCCCCCCEECCCCCCC
KNACLKPGKRCKLINNNKRTNCELQHTITVRDGSVGKEGLPMRLERLTHNKIKIFLTFDD
CCCCCCCCCEEEEECCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHCCCCEEEEEEEEHH
LLDRGLTKDDLWRDTFKVHQLFRDMIEEASEELGFEVNGSIAVEVYSLPAQGMVVIVTNE
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCEEEEEEEECCCCCEEEEEECC
GDYNDIEEEFADDYIEMQVTLDESDDIFYEFQTFEDVIQLAHRLCAVGCLDGTLYSYQGR
CCCCHHHHHHCCCEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCE
FYLHVAEEPPIPLDNFVALLAEFGNPATITIHRVQEYGKRLMERRAIEQLVHYFRAN
EEEEECCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]