Click here to switch to the map view.

The map label for this gene is prsW [H]

Identifier: 138895809

GI number: 138895809

Start: 2296032

End: 2296727

Strand: Reverse

Name: prsW [H]

Synonym: GTNG_2168

Alternate gene names: 138895809

Gene position: 2296727-2296032 (Counterclockwise)

Preceding gene: 138895810

Following gene: 138895808

Centisome position: 64.69

GC content: 47.13

Gene sequence:

>696_bases
ATGTTTTCGCTCATTTCTGCCGGCGTCGCCCCTGGGGTGGCGCTGCTCAGTTATTTTTATTTAAAGGACGAGTATGAAGC
TGAACCGTTGTCTTTTGTGTTGCGCATGTTTTTCTTCGGTGTTCTCCTTGTTTTTCCCATCATGTTTATTCAATACGTGT
TGGTGGAAGAAAAAATCATTTCGTCGCCGGCGGCTGAAGCGTTTTTATCTGCGGCGTTGCTCGAAGAGTTTGTCAAATGG
TTTATTATCTATTTTTTTGTGTATGACCACGACGAATTTGATGAGCCGTACGACGGCATTGTGTATAGTGCCAGCGTCTC
ATTAGGTTTTGCGACGTTAGAGAACATTTTATACTTGCTAGCCAACGGATTGGAGACAGCCGTCACCCGGGCACTGCTGC
CGGTGTCAAGCCATGCGCTGTTTGCCGTCATTATGGGGTTTTATTTCGGCAAGGCGAAATTTGCTGGCCGAAAGCGCCGT
TATTATTTATGGGCATCGTTTTTGCTGCCGTTTTTTCTTCATGGCATCTATGATTGGATTTTGTTGGCCGAGAAACAATG
GGGTTATTACATGGGGCCGTTTATGCTTGCCTTATGGTGGGTGGCGCTGCGCAAAGTGAAGAAGGCAAAAGGGTACATCC
GCTGTCAAGTGACGTCGTCGGCGCAAGGAGTCGTTCGCAAAGTAGAACTGCCTTAA

Upstream 100 bases:

>100_bases
CTTGTTTGCCTATTAGGTGAAGTTGCCTAGTAAATTCTCTTTTTCACTCCCTAGTTTCGTGTTACGATAGAGGTAAAAAG
ACAGAGAAACGGGGATCGAT

Downstream 100 bases:

>100_bases
AAAATGAAGATGGTTGCTATAGCAAGATGTTGGAACGTGAAAAGGGGCATCCGAAAGTCGAAAACACGGCTTTCCGGACG
GCCCCTTCTTCTTTTTTCTG

Product: hypothetical protein

Products: NA

Alternate protein names: Protease responsible for activating sigma-W [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MFSLISAGVAPGVALLSYFYLKDEYEAEPLSFVLRMFFFGVLLVFPIMFIQYVLVEEKIISSPAAEAFLSAALLEEFVKW
FIIYFFVYDHDEFDEPYDGIVYSASVSLGFATLENILYLLANGLETAVTRALLPVSSHALFAVIMGFYFGKAKFAGRKRR
YYLWASFLLPFFLHGIYDWILLAEKQWGYYMGPFMLALWWVALRKVKKAKGYIRCQVTSSAQGVVRKVELP

Sequences:

>Translated_231_residues
MFSLISAGVAPGVALLSYFYLKDEYEAEPLSFVLRMFFFGVLLVFPIMFIQYVLVEEKIISSPAAEAFLSAALLEEFVKW
FIIYFFVYDHDEFDEPYDGIVYSASVSLGFATLENILYLLANGLETAVTRALLPVSSHALFAVIMGFYFGKAKFAGRKRR
YYLWASFLLPFFLHGIYDWILLAEKQWGYYMGPFMLALWWVALRKVKKAKGYIRCQVTSSAQGVVRKVELP
>Mature_231_residues
MFSLISAGVAPGVALLSYFYLKDEYEAEPLSFVLRMFFFGVLLVFPIMFIQYVLVEEKIISSPAAEAFLSAALLEEFVKW
FIIYFFVYDHDEFDEPYDGIVYSASVSLGFATLENILYLLANGLETAVTRALLPVSSHALFAVIMGFYFGKAKFAGRKRR
YYLWASFLLPFFLHGIYDWILLAEKQWGYYMGPFMLALWWVALRKVKKAKGYIRCQVTSSAQGVVRKVELP

Specific function: Is responsible for Site-1 cleavage of the RsiW anti- sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sig

COG id: COG2339

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease prsW family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 26511; Mature: 26511

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSLISAGVAPGVALLSYFYLKDEYEAEPLSFVLRMFFFGVLLVFPIMFIQYVLVEEKII
CCCHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSPAAEAFLSAALLEEFVKWFIIYFFVYDHDEFDEPYDGIVYSASVSLGFATLENILYLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHH
ANGLETAVTRALLPVSSHALFAVIMGFYFGKAKFAGRKRRYYLWASFLLPFFLHGIYDWI
HCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LLAEKQWGYYMGPFMLALWWVALRKVKKAKGYIRCQVTSSAQGVVRKVELP
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHCCCCC
>Mature Secondary Structure
MFSLISAGVAPGVALLSYFYLKDEYEAEPLSFVLRMFFFGVLLVFPIMFIQYVLVEEKII
CCCHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSPAAEAFLSAALLEEFVKWFIIYFFVYDHDEFDEPYDGIVYSASVSLGFATLENILYLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHH
ANGLETAVTRALLPVSSHALFAVIMGFYFGKAKFAGRKRRYYLWASFLLPFFLHGIYDWI
HCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LLAEKQWGYYMGPFMLALWWVALRKVKKAKGYIRCQVTSSAQGVVRKVELP
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA