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The map label for this gene is trpB [H]

Identifier: 138895778

GI number: 138895778

Start: 2265312

End: 2266526

Strand: Reverse

Name: trpB [H]

Synonym: GTNG_2134

Alternate gene names: 138895778

Gene position: 2266526-2265312 (Counterclockwise)

Preceding gene: 138895779

Following gene: 138895777

Centisome position: 63.84

GC content: 54.32

Gene sequence:

>1215_bases
ATGGAACACGTTCCGAATGAACACGGGCGATTTGGTGATTTTGGCGGCAAGTTTGTTCCAGAGACGCTCATGCTCCCCCT
TGAGGAAATTGAAACCGAGCTGGACAAAGCGCTTGCCGACGAGTCGTTCAGGCAAGAATATATCCGGATTTTGCAGCACT
ACTCGGGGCGGCCGACTCCGCTTACGTTTGCACCAAATTTGACACGACAGCTTGGTGGGGCGAAAATTTATTTAAAGCGC
GAAGATTTAAACCACACCGGCGCCCATAAAATCAACAACGCTATCGGCCAGGCGCTCTTGGCGAAACGGATGGGCAAGAA
AAAGTTGATCGCTGAGACCGGCGCTGGGCAGCACGGGGTTGCGGCAGCGACGGTGGCCGCTCACTTCGGTATGGAATGCA
TCGTCTTTATGGGCGAGGAAGACATGAAGCGGCAAGAGTTGAACGTGTTTCGGATGAAGCTGTTAGGCGCCGAAGTTGTG
CCGGTGTTAAGCGGCAACCGGACGTTAAAAGATGCGACAAATGAGGCGATTCGTTATTGGGTCGCCCATTGCGATGACCA
TTTTTACATGATCGGTTCGGTTGTCGGCCCGCATCCGTACCCGAAAATGGTGCGCGAGTTTCAGCGCGTGATCGGCGATG
AGGCGAAAGAACAGTTTCTCGCCGGCGAAGGAACGCTGCCGGATGTGATTGTTGCCTGCGTCGGCGGAGGCAGCAACGCC
ATCGGCATGTTTTATCCGTTTTTGCAAGACGATGTCCGTCTCGTCGGCGTGGAAGCGGCCGGCAAAGGAATCGATACTCC
GCACCATGCGGCGACGATTGCAAAAGGGACAAAAGGCGTTATCCATGGGGCAATGACGTACTTGTTACAAGATGAGTACG
GGCAAATTATTGAACCGTATTCAATTTCCGCCGGCCTTGATTACCCTGGCGTCGGTCCGGAACATGCGTATTTGGCCAGC
ATCGGCCGCGTTCGTTATGAGAGTGTGACCGATGAAGAAGCAGTGGCTGCGTTTCAGCTTCTGGCGCAAACTGAAGGCAT
CATTCCAGCCATTGAGTCGGCGCATGCGGTGGCCAAAGCTGTCGAGCTTGCCCGCCAAATGACGCCGGATGAGACGGTGC
TTATTTGCCTGTCCGGCCGCGGCGATAAAGATGTGCAAATGATGATGCACCATCTTGGGGTGAAAGAAGGTGAAGACGTT
GCGTCTGCCCGTTAA

Upstream 100 bases:

>100_bases
ATGCTCGGACGATGAAACAGCGCCGCTTCGGCAATCGAGAGGTGCGCTTTCACACGAAATTCGACATTTAATCTTAAGAA
AAAAGAAGGTGGCTTTGATG

Downstream 100 bases:

>100_bases
CCGATCGTTATTTATTCCGTTTATTGTTGCCGGCGACCCGTCTGCTGATTTGACTGTTGACCTCGCTTTGGCGCTGCAAG
ACGCCGGTGCTGACGTGTTG

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MEHVPNEHGRFGDFGGKFVPETLMLPLEEIETELDKALADESFRQEYIRILQHYSGRPTPLTFAPNLTRQLGGAKIYLKR
EDLNHTGAHKINNAIGQALLAKRMGKKKLIAETGAGQHGVAAATVAAHFGMECIVFMGEEDMKRQELNVFRMKLLGAEVV
PVLSGNRTLKDATNEAIRYWVAHCDDHFYMIGSVVGPHPYPKMVREFQRVIGDEAKEQFLAGEGTLPDVIVACVGGGSNA
IGMFYPFLQDDVRLVGVEAAGKGIDTPHHAATIAKGTKGVIHGAMTYLLQDEYGQIIEPYSISAGLDYPGVGPEHAYLAS
IGRVRYESVTDEEAVAAFQLLAQTEGIIPAIESAHAVAKAVELARQMTPDETVLICLSGRGDKDVQMMMHHLGVKEGEDV
ASAR

Sequences:

>Translated_404_residues
MEHVPNEHGRFGDFGGKFVPETLMLPLEEIETELDKALADESFRQEYIRILQHYSGRPTPLTFAPNLTRQLGGAKIYLKR
EDLNHTGAHKINNAIGQALLAKRMGKKKLIAETGAGQHGVAAATVAAHFGMECIVFMGEEDMKRQELNVFRMKLLGAEVV
PVLSGNRTLKDATNEAIRYWVAHCDDHFYMIGSVVGPHPYPKMVREFQRVIGDEAKEQFLAGEGTLPDVIVACVGGGSNA
IGMFYPFLQDDVRLVGVEAAGKGIDTPHHAATIAKGTKGVIHGAMTYLLQDEYGQIIEPYSISAGLDYPGVGPEHAYLAS
IGRVRYESVTDEEAVAAFQLLAQTEGIIPAIESAHAVAKAVELARQMTPDETVLICLSGRGDKDVQMMMHHLGVKEGEDV
ASAR
>Mature_404_residues
MEHVPNEHGRFGDFGGKFVPETLMLPLEEIETELDKALADESFRQEYIRILQHYSGRPTPLTFAPNLTRQLGGAKIYLKR
EDLNHTGAHKINNAIGQALLAKRMGKKKLIAETGAGQHGVAAATVAAHFGMECIVFMGEEDMKRQELNVFRMKLLGAEVV
PVLSGNRTLKDATNEAIRYWVAHCDDHFYMIGSVVGPHPYPKMVREFQRVIGDEAKEQFLAGEGTLPDVIVACVGGGSNA
IGMFYPFLQDDVRLVGVEAAGKGIDTPHHAATIAKGTKGVIHGAMTYLLQDEYGQIIEPYSISAGLDYPGVGPEHAYLAS
IGRVRYESVTDEEAVAAFQLLAQTEGIIPAIESAHAVAKAVELARQMTPDETVLICLSGRGDKDVQMMMHHLGVKEGEDV
ASAR

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=377, Percent_Identity=54.1114058355438, Blast_Score=408, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6321412, Length=396, Percent_Identity=57.5757575757576, Blast_Score=467, Evalue=1e-132,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 44031; Mature: 44031

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHVPNEHGRFGDFGGKFVPETLMLPLEEIETELDKALADESFRQEYIRILQHYSGRPTP
CCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LTFAPNLTRQLGGAKIYLKREDLNHTGAHKINNAIGQALLAKRMGKKKLIAETGAGQHGV
EEECCCHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCH
AAATVAAHFGMECIVFMGEEDMKRQELNVFRMKLLGAEVVPVLSGNRTLKDATNEAIRYW
HHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCHHEEEECCCCHHHHHHHHHHHHH
VAHCDDHFYMIGSVVGPHPYPKMVREFQRVIGDEAKEQFLAGEGTLPDVIVACVGGGSNA
HHHCCCCEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHEEECCCCCC
IGMFYPFLQDDVRLVGVEAAGKGIDTPHHAATIAKGTKGVIHGAMTYLLQDEYGQIIEPY
HHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCEECCC
SISAGLDYPGVGPEHAYLASIGRVRYESVTDEEAVAAFQLLAQTEGIIPAIESAHAVAKA
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VELARQMTPDETVLICLSGRGDKDVQMMMHHLGVKEGEDVASAR
HHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCHHHCCC
>Mature Secondary Structure
MEHVPNEHGRFGDFGGKFVPETLMLPLEEIETELDKALADESFRQEYIRILQHYSGRPTP
CCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LTFAPNLTRQLGGAKIYLKREDLNHTGAHKINNAIGQALLAKRMGKKKLIAETGAGQHGV
EEECCCHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCH
AAATVAAHFGMECIVFMGEEDMKRQELNVFRMKLLGAEVVPVLSGNRTLKDATNEAIRYW
HHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCHHEEEECCCCHHHHHHHHHHHHH
VAHCDDHFYMIGSVVGPHPYPKMVREFQRVIGDEAKEQFLAGEGTLPDVIVACVGGGSNA
HHHCCCCEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHEEECCCCCC
IGMFYPFLQDDVRLVGVEAAGKGIDTPHHAATIAKGTKGVIHGAMTYLLQDEYGQIIEPY
HHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCEECCC
SISAGLDYPGVGPEHAYLASIGRVRYESVTDEEAVAAFQLLAQTEGIIPAIESAHAVAKA
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VELARQMTPDETVLICLSGRGDKDVQMMMHHLGVKEGEDVASAR
HHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA