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The map label for this gene is galE [H]

Identifier: 138895729

GI number: 138895729

Start: 2219231

End: 2220217

Strand: Reverse

Name: galE [H]

Synonym: GTNG_2085

Alternate gene names: 138895729

Gene position: 2220217-2219231 (Counterclockwise)

Preceding gene: 138895730

Following gene: 138895728

Centisome position: 62.54

GC content: 51.87

Gene sequence:

>987_bases
ATGATTTTGATTTGTGGCGGGGCAGGGTATATCGGCAGTCATGCGGTGTACCGTCTGCTCGAAAAAGGGGAAGAGGTCAT
TGTTGTTGATAACTTGCAGACCGGGCACAGAGAAGCGGTGCATCCGGATGCGCGGTTTTGCCAAGGGGATATTCGCGACC
GCGACTTTTTGCGCACGGTGTTTCAGCAGTATGATATTGAGGCGGTGATCCATTTTGCGGCCAACTCATTGGTTGGTGAA
AGCATGGAAGAGCCGCTGAAATATTACGACAACAATGTGTACGGCACACAAGTGTTGCTTGAAGTGATGAAGGAATTTGA
TGTTAGACAAATTGTTTTTTCTTCAACCGCAGCGGTGTATGGGGAACCGAAACAAATCCCGATCGTCGAAACTGATCCGA
CAGAGCCAACGAACGCATATGGAGAAACGAAGCTGGCGATGGAAAAAATGATGAAATGGGCAGATCGCGCCTACGGTATC
CGCTCGATTTCGCTCCGCTATTTCAATGTCGCTGGGGCGTATGGCACGACGATCGGCGAAGATCACAATCCGGAGACGCA
TCTGATTCCGTTGATTTTAAAAGTGCCGCTCGGCCAGCGCGAGGAAATTTTCATTTTCGGCGATGACTATGATACGCCGG
ACGGTACGTGCATTCGTGATTACATTCATGTGCTCGATCTTGTTGATGCCCACGTTTTGGCGCTTAACAAACTGCGGAAC
GGGGCGGATAGTGATGTATACAATTTAGGCAACGGCAACGGGTTTAGCGTTAAAGAAGTGATTGAAGCGGCGCGGCAAGT
GACCGGGCATCCGATTCCGGCTCGTGTCATGGCACGGCGGCCAGGCGACCCAGCGAAACTCGTCGCCTCGTCCGACAAAG
CGAAGCGCGAACTCGGCTGGGAGCCAAACTACCCGTCCATTACAGATATCGTCGCTTCGGCATGGGAATGGCATCAAGCA
CGGCCAAACGGTTATCGGGGTGTATGA

Upstream 100 bases:

>100_bases
GAAGGACATATGCCGAAAAAATCGGCTATGAAGCGAGCTTTTATGTCGTTGACGTTGGCAATGGGGCGCGTGAACTGATA
GAAATGGAGGAGATGTGCCG

Downstream 100 bases:

>100_bases
CAATGGAAACGATCTTTGCGGCGATTGAACAACTGATTCATTATGCTCAACATCGTGGTCTGTTAGCGCCGGAAGATGTG
GTGTACGCGCGCAACCGCCT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MILICGGAGYIGSHAVYRLLEKGEEVIVVDNLQTGHREAVHPDARFCQGDIRDRDFLRTVFQQYDIEAVIHFAANSLVGE
SMEEPLKYYDNNVYGTQVLLEVMKEFDVRQIVFSSTAAVYGEPKQIPIVETDPTEPTNAYGETKLAMEKMMKWADRAYGI
RSISLRYFNVAGAYGTTIGEDHNPETHLIPLILKVPLGQREEIFIFGDDYDTPDGTCIRDYIHVLDLVDAHVLALNKLRN
GADSDVYNLGNGNGFSVKEVIEAARQVTGHPIPARVMARRPGDPAKLVASSDKAKRELGWEPNYPSITDIVASAWEWHQA
RPNGYRGV

Sequences:

>Translated_328_residues
MILICGGAGYIGSHAVYRLLEKGEEVIVVDNLQTGHREAVHPDARFCQGDIRDRDFLRTVFQQYDIEAVIHFAANSLVGE
SMEEPLKYYDNNVYGTQVLLEVMKEFDVRQIVFSSTAAVYGEPKQIPIVETDPTEPTNAYGETKLAMEKMMKWADRAYGI
RSISLRYFNVAGAYGTTIGEDHNPETHLIPLILKVPLGQREEIFIFGDDYDTPDGTCIRDYIHVLDLVDAHVLALNKLRN
GADSDVYNLGNGNGFSVKEVIEAARQVTGHPIPARVMARRPGDPAKLVASSDKAKRELGWEPNYPSITDIVASAWEWHQA
RPNGYRGV
>Mature_328_residues
MILICGGAGYIGSHAVYRLLEKGEEVIVVDNLQTGHREAVHPDARFCQGDIRDRDFLRTVFQQYDIEAVIHFAANSLVGE
SMEEPLKYYDNNVYGTQVLLEVMKEFDVRQIVFSSTAAVYGEPKQIPIVETDPTEPTNAYGETKLAMEKMMKWADRAYGI
RSISLRYFNVAGAYGTTIGEDHNPETHLIPLILKVPLGQREEIFIFGDDYDTPDGTCIRDYIHVLDLVDAHVLALNKLRN
GADSDVYNLGNGNGFSVKEVIEAARQVTGHPIPARVMARRPGDPAKLVASSDKAKRELGWEPNYPSITDIVASAWEWHQA
RPNGYRGV

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=343, Percent_Identity=40.8163265306122, Blast_Score=258, Evalue=5e-69,
Organism=Homo sapiens, GI56118217, Length=343, Percent_Identity=40.8163265306122, Blast_Score=258, Evalue=5e-69,
Organism=Homo sapiens, GI189083684, Length=343, Percent_Identity=40.8163265306122, Blast_Score=258, Evalue=5e-69,
Organism=Homo sapiens, GI7657641, Length=345, Percent_Identity=26.6666666666667, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI42516563, Length=315, Percent_Identity=27.9365079365079, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI116268111, Length=249, Percent_Identity=28.9156626506024, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI239745448, Length=289, Percent_Identity=23.8754325259516, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI310132178, Length=289, Percent_Identity=23.8754325259516, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI310113012, Length=289, Percent_Identity=23.8754325259516, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1786974, Length=337, Percent_Identity=40.9495548961424, Blast_Score=252, Evalue=2e-68,
Organism=Escherichia coli, GI48994969, Length=364, Percent_Identity=28.2967032967033, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788353, Length=336, Percent_Identity=28.2738095238095, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790049, Length=329, Percent_Identity=26.1398176291793, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71982035, Length=344, Percent_Identity=36.046511627907, Blast_Score=224, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI71982038, Length=346, Percent_Identity=35.8381502890173, Blast_Score=224, Evalue=6e-59,
Organism=Caenorhabditis elegans, GI17539532, Length=316, Percent_Identity=26.8987341772152, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI115532424, Length=345, Percent_Identity=24.0579710144928, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17568069, Length=334, Percent_Identity=24.5508982035928, Blast_Score=71, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=352, Percent_Identity=42.8977272727273, Blast_Score=255, Evalue=5e-69,
Organism=Drosophila melanogaster, GI19923002, Length=345, Percent_Identity=41.7391304347826, Blast_Score=254, Evalue=4e-68,
Organism=Drosophila melanogaster, GI21356223, Length=314, Percent_Identity=27.7070063694268, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36671; Mature: 36671

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILICGGAGYIGSHAVYRLLEKGEEVIVVDNLQTGHREAVHPDARFCQGDIRDRDFLRTV
CEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHCCCCCCHHHHHHH
FQQYDIEAVIHFAANSLVGESMEEPLKYYDNNVYGTQVLLEVMKEFDVRQIVFSSTAAVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHCCHHHC
GEPKQIPIVETDPTEPTNAYGETKLAMEKMMKWADRAYGIRSISLRYFNVAGAYGTTIGE
CCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCC
DHNPETHLIPLILKVPLGQREEIFIFGDDYDTPDGTCIRDYIHVLDLVDAHVLALNKLRN
CCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GADSDVYNLGNGNGFSVKEVIEAARQVTGHPIPARVMARRPGDPAKLVASSDKAKRELGW
CCCCCCEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHEECCCHHHHHCCC
EPNYPSITDIVASAWEWHQARPNGYRGV
CCCCCHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MILICGGAGYIGSHAVYRLLEKGEEVIVVDNLQTGHREAVHPDARFCQGDIRDRDFLRTV
CEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHCCCCCCHHHHHHH
FQQYDIEAVIHFAANSLVGESMEEPLKYYDNNVYGTQVLLEVMKEFDVRQIVFSSTAAVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHCCHHHC
GEPKQIPIVETDPTEPTNAYGETKLAMEKMMKWADRAYGIRSISLRYFNVAGAYGTTIGE
CCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCC
DHNPETHLIPLILKVPLGQREEIFIFGDDYDTPDGTCIRDYIHVLDLVDAHVLALNKLRN
CCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GADSDVYNLGNGNGFSVKEVIEAARQVTGHPIPARVMARRPGDPAKLVASSDKAKRELGW
CCCCCCEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHEECCCHHHHHCCC
EPNYPSITDIVASAWEWHQARPNGYRGV
CCCCCHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]