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The map label for this gene is paaK [H]

Identifier: 138895577

GI number: 138895577

Start: 2052373

End: 2053704

Strand: Reverse

Name: paaK [H]

Synonym: GTNG_1930

Alternate gene names: 138895577

Gene position: 2053704-2052373 (Counterclockwise)

Preceding gene: 138895578

Following gene: 138895576

Centisome position: 57.85

GC content: 52.7

Gene sequence:

>1332_bases
ATGATTTTGCATGACATTGAGAGGGCCGAGCGCATTGAGCTGAAAGGGCTCCAGCTCAGCCGGCTCCGGGCAACGGCGGA
ACGCGTGTATGAGCGGGTGCCATTTTATCGTGAGCGATTTGACGAAACAGGAGTGAAACCTGAGGATATCCGGACATTGG
ATGATGTGCGCAGGCTGCCGTTTACGACAAAAAGCGATTTGCGCGCGCATTATCCGTTCGGTTTGCTAGCAGTTGATCTC
ACTCAATGCGTCCGTTTGCATGCGTCAAGCGGCACGAGTGGAAAACCGACCGTTGTCGCCTATACAAAGCGTGACATTGA
TCATTGGGCCGATATTGTAGCGCGGGCGTTGGCGATAGCTGGTGGAAAGCCGGGAGATGTCGTTCACAATGCGTACGGAT
ACGGGTTATTTACCGGCGGGCTCGGGCTTCATTACGGCAGTGAGCGGCTCGGAGCGGTCACTGTTCCTGTTTCTGGCGGC
AATACGGAACGGCAAATAATGATTATTGAAGATTTCCGCCCGACCATCATTTGCGGGACACCGTCCTATGTGTTGAACAT
TGCTGAGCGGATGAAAGAGTTGGGCAAAGATCCGCGGCAAACATCGCTGAAATACGGGATTTTTGGAGCGGAGCCGTGGT
CGGAAGAGATGCGGCGCACGCTTGAAGAGACATTTGACATCAAAGCGTGCGACATTTATGGGTTAAGTGAAGTGATTGGC
CCTGGGGTGGCTATGGAATGTCATGAAGCGCAAGATGGACTTCATATCGCCGAAGACCATTTCTTTGTCGAGGTCATTAA
TCCGAACACACTTGAACCGGTAGGGGAAGGGGAAGAAGGAGAGCTTGTCTTTACGAGTTTGACGAAAGAGGCGTTTCCAG
TCATCCGCTATCGGACGGGCGATATTGCTTCGGTGACAAGGGAGCGATGTGCTTGCGGGCGAACAACGGTGCGCATGTCA
CGGGTGAAGGGACGTGTTGACGATATGATTATCATTCGTGGCGTCAATGTGTTCCCATCAGAAATTGAACACCATCTGCT
TCGTGTTTCGGAACTGGCTCCGCACTATCAGCTACACCGGTTCCGCCACGGTCATTTGGAAGCGGTGGAGTTGCACGCGG
AAGTGACAGATGATTTTTACAGCCAGATCGGCGGCGATTTACAAAGTGAGCAGGCCGTTGCGCTTGCTCGGCGAGTTCAA
TCGCTGTTGAAAACACACTGTCTCGTTTCGATTGGTGTTCGTCTCCATCCTCCGAAAACCCTCCCTCGTTCAGAAGGGAA
AGCGGTGCGTGTCATCGACCGACGTAAGTTCGAAGCGAAACAATCCGTTTGA

Upstream 100 bases:

>100_bases
TTTAAAGTTAGGTGTGATATGTAATTTATATAACGTTAATATAACGTTATATATTTTTGTATCTTTGAAAACGCTTTATA
TTAAGGGGGAGTCAGGAAGG

Downstream 100 bases:

>100_bases
ATTGAAAGAAAAGTAGAAAAAAAGATTGCAAAATTATATAACATTAAAATATAATAACGTTAGATAAACGTTATATGATT
TTTAATTATATTTAATAGGG

Product: phenylacetyl-CoA ligase in the phenylacetic acidcatabolic pathway

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MILHDIERAERIELKGLQLSRLRATAERVYERVPFYRERFDETGVKPEDIRTLDDVRRLPFTTKSDLRAHYPFGLLAVDL
TQCVRLHASSGTSGKPTVVAYTKRDIDHWADIVARALAIAGGKPGDVVHNAYGYGLFTGGLGLHYGSERLGAVTVPVSGG
NTERQIMIIEDFRPTIICGTPSYVLNIAERMKELGKDPRQTSLKYGIFGAEPWSEEMRRTLEETFDIKACDIYGLSEVIG
PGVAMECHEAQDGLHIAEDHFFVEVINPNTLEPVGEGEEGELVFTSLTKEAFPVIRYRTGDIASVTRERCACGRTTVRMS
RVKGRVDDMIIIRGVNVFPSEIEHHLLRVSELAPHYQLHRFRHGHLEAVELHAEVTDDFYSQIGGDLQSEQAVALARRVQ
SLLKTHCLVSIGVRLHPPKTLPRSEGKAVRVIDRRKFEAKQSV

Sequences:

>Translated_443_residues
MILHDIERAERIELKGLQLSRLRATAERVYERVPFYRERFDETGVKPEDIRTLDDVRRLPFTTKSDLRAHYPFGLLAVDL
TQCVRLHASSGTSGKPTVVAYTKRDIDHWADIVARALAIAGGKPGDVVHNAYGYGLFTGGLGLHYGSERLGAVTVPVSGG
NTERQIMIIEDFRPTIICGTPSYVLNIAERMKELGKDPRQTSLKYGIFGAEPWSEEMRRTLEETFDIKACDIYGLSEVIG
PGVAMECHEAQDGLHIAEDHFFVEVINPNTLEPVGEGEEGELVFTSLTKEAFPVIRYRTGDIASVTRERCACGRTTVRMS
RVKGRVDDMIIIRGVNVFPSEIEHHLLRVSELAPHYQLHRFRHGHLEAVELHAEVTDDFYSQIGGDLQSEQAVALARRVQ
SLLKTHCLVSIGVRLHPPKTLPRSEGKAVRVIDRRKFEAKQSV
>Mature_443_residues
MILHDIERAERIELKGLQLSRLRATAERVYERVPFYRERFDETGVKPEDIRTLDDVRRLPFTTKSDLRAHYPFGLLAVDL
TQCVRLHASSGTSGKPTVVAYTKRDIDHWADIVARALAIAGGKPGDVVHNAYGYGLFTGGLGLHYGSERLGAVTVPVSGG
NTERQIMIIEDFRPTIICGTPSYVLNIAERMKELGKDPRQTSLKYGIFGAEPWSEEMRRTLEETFDIKACDIYGLSEVIG
PGVAMECHEAQDGLHIAEDHFFVEVINPNTLEPVGEGEEGELVFTSLTKEAFPVIRYRTGDIASVTRERCACGRTTVRMS
RVKGRVDDMIIIRGVNVFPSEIEHHLLRVSELAPHYQLHRFRHGHLEAVELHAEVTDDFYSQIGGDLQSEQAVALARRVQ
SLLKTHCLVSIGVRLHPPKTLPRSEGKAVRVIDRRKFEAKQSV

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=436, Percent_Identity=52.0642201834862, Blast_Score=456, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 49701; Mature: 49701

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILHDIERAERIELKGLQLSRLRATAERVYERVPFYRERFDETGVKPEDIRTLDDVRRLP
CCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHCC
FTTKSDLRAHYPFGLLAVDLTQCVRLHASSGTSGKPTVVAYTKRDIDHWADIVARALAIA
CCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHCHHHHHHHHHHHHHHC
GGKPGDVVHNAYGYGLFTGGLGLHYGSERLGAVTVPVSGGNTERQIMIIEDFRPTIICGT
CCCCCCHHHCCCCCEEEECCCEECCCCCCCCEEEEEECCCCCCEEEEEEECCCCEEEECC
PSYVLNIAERMKELGKDPRQTSLKYGIFGAEPWSEEMRRTLEETFDIKACDIYGLSEVIG
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHC
PGVAMECHEAQDGLHIAEDHFFVEVINPNTLEPVGEGEEGELVFTSLTKEAFPVIRYRTG
CCCEEEHHHCCCCCEEECCCEEEEEECCCCCCCCCCCCCCCEEEEEHHHHHCCEEEEECC
DIASVTRERCACGRTTVRMSRVKGRVDDMIIIRGVNVFPSEIEHHLLRVSELAPHYQLHR
CHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHH
FRHGHLEAVELHAEVTDDFYSQIGGDLQSEQAVALARRVQSLLKTHCLVSIGVRLHPPKT
HCCCCCEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEECEEECCCCC
LPRSEGKAVRVIDRRKFEAKQSV
CCCCCCCEEEEEHHHHHHHHCCC
>Mature Secondary Structure
MILHDIERAERIELKGLQLSRLRATAERVYERVPFYRERFDETGVKPEDIRTLDDVRRLP
CCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHCC
FTTKSDLRAHYPFGLLAVDLTQCVRLHASSGTSGKPTVVAYTKRDIDHWADIVARALAIA
CCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHCHHHHHHHHHHHHHHC
GGKPGDVVHNAYGYGLFTGGLGLHYGSERLGAVTVPVSGGNTERQIMIIEDFRPTIICGT
CCCCCCHHHCCCCCEEEECCCEECCCCCCCCEEEEEECCCCCCEEEEEEECCCCEEEECC
PSYVLNIAERMKELGKDPRQTSLKYGIFGAEPWSEEMRRTLEETFDIKACDIYGLSEVIG
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHC
PGVAMECHEAQDGLHIAEDHFFVEVINPNTLEPVGEGEEGELVFTSLTKEAFPVIRYRTG
CCCEEEHHHCCCCCEEECCCEEEEEECCCCCCCCCCCCCCCEEEEEHHHHHCCEEEEECC
DIASVTRERCACGRTTVRMSRVKGRVDDMIIIRGVNVFPSEIEHHLLRVSELAPHYQLHR
CHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHH
FRHGHLEAVELHAEVTDDFYSQIGGDLQSEQAVALARRVQSLLKTHCLVSIGVRLHPPKT
HCCCCCEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEECEEECCCCC
LPRSEGKAVRVIDRRKFEAKQSV
CCCCCCCEEEEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]