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The map label for this gene is paaX [H]

Identifier: 138895566

GI number: 138895566

Start: 2042637

End: 2043503

Strand: Reverse

Name: paaX [H]

Synonym: GTNG_1919

Alternate gene names: 138895566

Gene position: 2043503-2042637 (Counterclockwise)

Preceding gene: 138895567

Following gene: 138895564

Centisome position: 57.56

GC content: 48.21

Gene sequence:

>867_bases
ATGAATACACGCTCGATGATTTTCACGATTTACGGCGACTACATCCGCCATTACGGCGGTGAAATTTGGATCGGGAGCTT
AATCCGCCTCCTTCGCGAGTTTGGCCACAATGACCAAGCGGTGCGGGCAGCGGTGTCGCGCATGAGTAAACAAGGTTGGA
TTCGGGCTGAAAAACGCGGCAATAAAAGCTATTACTCACTCACTGAGCGCGGTGTGAAGCGGATGGAAGAGGCGGCGCGC
CGCATTTATAAAACGCGGCCCGAGCATTGGGACGGCAAATGGCGCATTCTCATTTATACGATTCCTGAAGACAAGCGGCA
TTTGCGCGACGAATTGCGGAAGGAGCTTGTTTGGAGCGGGTTTGGCACGATTTCGAACAGCTGTTGGATCTCGCCGAATA
ATTTGGAGCAGCAAGTGTATGACTTAATTGACAAGTATCATATTCACCCGTACGTTGACTTTTTCCTTGCTGAGTATGAT
GGGCCGCACATGAACAAACAGCTCGTCGAAAAGTGTTGGAACTTAGAAGAAATCAATCAAAAATATGAGCAGTTTATCGT
CACTTATAGTCAAAAATACGTGATTGATAAACATAAAATCGAACGTGGCGAAATGTCAGATGCGGAATGTTTCGTTGAAC
GGACGAAGCTCGTTCATGAATATCGGAAGTTTTTATTTATCGATCCGGGGTTACCTGAGGAATTGCTGCCAGACGAGTGG
ATGGGAAGCCATGCCGCTGCCTTGTTCAATGACTACTACCAACAGCTTGCCGCGCCAGCCAGCCGCTTTTTTGAGGCGGT
ATTTCGAGAAGGAGCGGAGCTTGGCAAAAAGGGAGAACAGGAGAAAGAAAAGGTGTCGTTTGAGTGA

Upstream 100 bases:

>100_bases
GCGGCTCTTTTTATTCCGCTTTTTTCTCGCCCGACTTGCCACCGTTATAAAAGTTTGTTACGATTATATTTCGAAAACAA
GGTAAAGGGAGTCCGTCCAG

Downstream 100 bases:

>100_bases
ATTCGTGGTGCATGGCTCAAGCCAAGCTATGCATCACGTTTTGTGTAATGATGAACATTTTGCCAATGCCCACGATGCTC
GAGACAGAAAACGGAATAGA

Product: putative regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MNTRSMIFTIYGDYIRHYGGEIWIGSLIRLLREFGHNDQAVRAAVSRMSKQGWIRAEKRGNKSYYSLTERGVKRMEEAAR
RIYKTRPEHWDGKWRILIYTIPEDKRHLRDELRKELVWSGFGTISNSCWISPNNLEQQVYDLIDKYHIHPYVDFFLAEYD
GPHMNKQLVEKCWNLEEINQKYEQFIVTYSQKYVIDKHKIERGEMSDAECFVERTKLVHEYRKFLFIDPGLPEELLPDEW
MGSHAAALFNDYYQQLAAPASRFFEAVFREGAELGKKGEQEKEKVSFE

Sequences:

>Translated_288_residues
MNTRSMIFTIYGDYIRHYGGEIWIGSLIRLLREFGHNDQAVRAAVSRMSKQGWIRAEKRGNKSYYSLTERGVKRMEEAAR
RIYKTRPEHWDGKWRILIYTIPEDKRHLRDELRKELVWSGFGTISNSCWISPNNLEQQVYDLIDKYHIHPYVDFFLAEYD
GPHMNKQLVEKCWNLEEINQKYEQFIVTYSQKYVIDKHKIERGEMSDAECFVERTKLVHEYRKFLFIDPGLPEELLPDEW
MGSHAAALFNDYYQQLAAPASRFFEAVFREGAELGKKGEQEKEKVSFE
>Mature_288_residues
MNTRSMIFTIYGDYIRHYGGEIWIGSLIRLLREFGHNDQAVRAAVSRMSKQGWIRAEKRGNKSYYSLTERGVKRMEEAAR
RIYKTRPEHWDGKWRILIYTIPEDKRHLRDELRKELVWSGFGTISNSCWISPNNLEQQVYDLIDKYHIHPYVDFFLAEYD
GPHMNKQLVEKCWNLEEINQKYEQFIVTYSQKYVIDKHKIERGEMSDAECFVERTKLVHEYRKFLFIDPGLPEELLPDEW
MGSHAAALFNDYYQQLAAPASRFFEAVFREGAELGKKGEQEKEKVSFE

Specific function: Negative regulator of the paaZ and paaABCDEFGHIJK catabolic operons. Binds the consensus sequence 5'- WWTRTGATTCGYGWT-3'. Binding of paaX is specifically inhibited by phenylacetyl-coenzyme A [H]

COG id: COG3327

COG function: function code K; Phenylacetic acid-responsive transcriptional repressor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787666, Length=266, Percent_Identity=35.3383458646617, Blast_Score=167, Evalue=5e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012906
- InterPro:   IPR013225
- InterPro:   IPR011965 [H]

Pfam domain/function: PF07848 PaaX; PF08223 PaaX_C [H]

EC number: NA

Molecular weight: Translated: 34315; Mature: 34315

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRSMIFTIYGDYIRHYGGEIWIGSLIRLLREFGHNDQAVRAAVSRMSKQGWIRAEKRG
CCCHHEEHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEHHHCC
NKSYYSLTERGVKRMEEAARRIYKTRPEHWDGKWRILIYTIPEDKRHLRDELRKELVWSG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHC
FGTISNSCWISPNNLEQQVYDLIDKYHIHPYVDFFLAEYDGPHMNKQLVEKCWNLEEINQ
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHH
KYEQFIVTYSQKYVIDKHKIERGEMSDAECFVERTKLVHEYRKFLFIDPGLPEELLPDEW
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHCCHHH
MGSHAAALFNDYYQQLAAPASRFFEAVFREGAELGKKGEQEKEKVSFE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCC
>Mature Secondary Structure
MNTRSMIFTIYGDYIRHYGGEIWIGSLIRLLREFGHNDQAVRAAVSRMSKQGWIRAEKRG
CCCHHEEHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEHHHCC
NKSYYSLTERGVKRMEEAARRIYKTRPEHWDGKWRILIYTIPEDKRHLRDELRKELVWSG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHC
FGTISNSCWISPNNLEQQVYDLIDKYHIHPYVDFFLAEYDGPHMNKQLVEKCWNLEEINQ
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHH
KYEQFIVTYSQKYVIDKHKIERGEMSDAECFVERTKLVHEYRKFLFIDPGLPEELLPDEW
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHCCHHH
MGSHAAALFNDYYQQLAAPASRFFEAVFREGAELGKKGEQEKEKVSFE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]