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The map label for this gene is pdhB [H]

Identifier: 138895558

GI number: 138895558

Start: 2034456

End: 2035454

Strand: Reverse

Name: pdhB [H]

Synonym: GTNG_1911

Alternate gene names: 138895558

Gene position: 2035454-2034456 (Counterclockwise)

Preceding gene: 138895559

Following gene: 138895557

Centisome position: 57.33

GC content: 50.75

Gene sequence:

>999_bases
ATGAGTGTAAAAGTAAGCACAAAATCGCTCACACTCGTGCAGGCGGTCAATGATGCGCTTCGCATCATGTTAAAAGAGCG
CGACGATGTCGTTTTGCTCGGAGAAGACGTAGGAAGAAACGGCGGTGTGTTTCGTGCCACCGACGGACTGCTTCAGGAGT
TTGGTGAGGAGAGGGTGATTGACACTCCGTTAAGCGAGGCGGGGTTTACAGGTGCAGCGATTGGAATGGCGCTAAATGGC
TTTCGTCCTGTTGTCGAAATTCAATTTTTAGGTTTTATTTATCCAGCCTATGAACAAATCATGACCCACGCGGCGCGTAT
GCGCTCGCGGACGAGGGGGCATTTTACGGTTCCATTGGTGATTCGTGCTCCATATGGCGCAGGCGTGCGAGCTCCGGAAA
TTCATTCAGACAGCACGGAAGCGCTGTTTACCCATATGCCAGGGGTGAAAGTCGTTTGCCCGTCGTCGCCGTATGACGCC
AAAGGGCTGTTGATCGCTGCGATTGAAGATCCAGACCCTGTGCTGTTTTTAGAGCCGATGCGCAACTATCGGGCGTTCCG
CGAAGACGTTCCTGAAGGAAAGTATACGGTTGACATCGGCAAAGGAAAAAAACTGCGCGAAGGGGAGGACGTGACGGTCA
TCGCGTGGGGAGCGATGGTGCCGGTCGCTATGAAGGCGGCAGAAGCCGCAGCGAAAAAGGGAATTGATGCTGATGTCATT
GATCTTCGTACACTTTATCCTCTTGACAAAGATATGATCGCCGAGTCAGTGCAAAAGACAGGAAGAACAGTGATTGTTCA
AGAAGCGCACGCTACAGGTGGATTGGCCAATGATATTTTGGCTGTCATCAACGATACATCGTTTTTCTATCAAAAAGCAC
CGGCCGAAAGGGTGACTGGATTTGATGTCCCCGTGCCGTTCTTCGCTCATGAAGATGACTATTTGCCAACGCCGGCGCGT
GTTTTGCATGCAATAGAAAAAGTCATGAATGACTCTTAA

Upstream 100 bases:

>100_bases
CCAACGCGTCTGACATGTTTGATTACGTATTCGCTGAACCGACGTGGACGATTGCTGAGCAGAAAGAGGCTTATCTTCAT
TGGAAACGGGTGATGGAAGG

Downstream 100 bases:

>100_bases
AGGTTGACGAATAATGAAACGTCATGACAGACAGAAAGTAATGCCCGAGCAGACTAGAGACGGCTCTCAGCAACGTGCTT
TCATCCAATCAGCTTTTGTA

Product: pyruvate decarboxylase subunit beta-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSVKVSTKSLTLVQAVNDALRIMLKERDDVVLLGEDVGRNGGVFRATDGLLQEFGEERVIDTPLSEAGFTGAAIGMALNG
FRPVVEIQFLGFIYPAYEQIMTHAARMRSRTRGHFTVPLVIRAPYGAGVRAPEIHSDSTEALFTHMPGVKVVCPSSPYDA
KGLLIAAIEDPDPVLFLEPMRNYRAFREDVPEGKYTVDIGKGKKLREGEDVTVIAWGAMVPVAMKAAEAAAKKGIDADVI
DLRTLYPLDKDMIAESVQKTGRTVIVQEAHATGGLANDILAVINDTSFFYQKAPAERVTGFDVPVPFFAHEDDYLPTPAR
VLHAIEKVMNDS

Sequences:

>Translated_332_residues
MSVKVSTKSLTLVQAVNDALRIMLKERDDVVLLGEDVGRNGGVFRATDGLLQEFGEERVIDTPLSEAGFTGAAIGMALNG
FRPVVEIQFLGFIYPAYEQIMTHAARMRSRTRGHFTVPLVIRAPYGAGVRAPEIHSDSTEALFTHMPGVKVVCPSSPYDA
KGLLIAAIEDPDPVLFLEPMRNYRAFREDVPEGKYTVDIGKGKKLREGEDVTVIAWGAMVPVAMKAAEAAAKKGIDADVI
DLRTLYPLDKDMIAESVQKTGRTVIVQEAHATGGLANDILAVINDTSFFYQKAPAERVTGFDVPVPFFAHEDDYLPTPAR
VLHAIEKVMNDS
>Mature_331_residues
SVKVSTKSLTLVQAVNDALRIMLKERDDVVLLGEDVGRNGGVFRATDGLLQEFGEERVIDTPLSEAGFTGAAIGMALNGF
RPVVEIQFLGFIYPAYEQIMTHAARMRSRTRGHFTVPLVIRAPYGAGVRAPEIHSDSTEALFTHMPGVKVVCPSSPYDAK
GLLIAAIEDPDPVLFLEPMRNYRAFREDVPEGKYTVDIGKGKKLREGEDVTVIAWGAMVPVAMKAAEAAAKKGIDADVID
LRTLYPLDKDMIAESVQKTGRTVIVQEAHATGGLANDILAVINDTSFFYQKAPAERVTGFDVPVPFFAHEDDYLPTPARV
LHAIEKVMNDS

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG0022

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557353, Length=327, Percent_Identity=42.5076452599388, Blast_Score=263, Evalue=2e-70,
Organism=Homo sapiens, GI34101272, Length=327, Percent_Identity=42.5076452599388, Blast_Score=263, Evalue=2e-70,
Organism=Homo sapiens, GI156564403, Length=327, Percent_Identity=36.085626911315, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI291084858, Length=327, Percent_Identity=34.8623853211009, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17506935, Length=323, Percent_Identity=44.5820433436532, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI17538422, Length=333, Percent_Identity=37.8378378378378, Blast_Score=218, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6319698, Length=331, Percent_Identity=37.4622356495468, Blast_Score=217, Evalue=2e-57,
Organism=Drosophila melanogaster, GI160714828, Length=325, Percent_Identity=41.8461538461538, Blast_Score=257, Evalue=8e-69,
Organism=Drosophila melanogaster, GI160714832, Length=325, Percent_Identity=41.8461538461538, Blast_Score=256, Evalue=1e-68,
Organism=Drosophila melanogaster, GI21358145, Length=330, Percent_Identity=39.0909090909091, Blast_Score=220, Evalue=9e-58,
Organism=Drosophila melanogaster, GI24650940, Length=330, Percent_Identity=39.0909090909091, Blast_Score=220, Evalue=9e-58,
Organism=Drosophila melanogaster, GI24650943, Length=88, Percent_Identity=40.9090909090909, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24650945, Length=88, Percent_Identity=40.9090909090909, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 36231; Mature: 36100

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKVSTKSLTLVQAVNDALRIMLKERDDVVLLGEDVGRNGGVFRATDGLLQEFGEERVI
CCEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECHHHHHHCCCCCEE
DTPLSEAGFTGAAIGMALNGFRPVVEIQFLGFIYPAYEQIMTHAARMRSRTRGHFTVPLV
CCCCHHCCCCHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
IRAPYGAGVRAPEIHSDSTEALFTHMPGVKVVCPSSPYDAKGLLIAAIEDPDPVLFLEPM
EECCCCCCCCCCCCCCCCHHHHHHCCCCCEEECCCCCCCCCCEEEEEECCCCCEEEECCH
RNYRAFREDVPEGKYTVDIGKGKKLREGEDVTVIAWGAMVPVAMKAAEAAAKKGIDADVI
HHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCEE
DLRTLYPLDKDMIAESVQKTGRTVIVQEAHATGGLANDILAVINDTSFFYQKAPAERVTG
HHHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHCCCHHHCCC
FDVPVPFFAHEDDYLPTPARVLHAIEKVMNDS
CCCCCCCEECCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVKVSTKSLTLVQAVNDALRIMLKERDDVVLLGEDVGRNGGVFRATDGLLQEFGEERVI
CEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECHHHHHHCCCCCEE
DTPLSEAGFTGAAIGMALNGFRPVVEIQFLGFIYPAYEQIMTHAARMRSRTRGHFTVPLV
CCCCHHCCCCHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
IRAPYGAGVRAPEIHSDSTEALFTHMPGVKVVCPSSPYDAKGLLIAAIEDPDPVLFLEPM
EECCCCCCCCCCCCCCCCHHHHHHCCCCCEEECCCCCCCCCCEEEEEECCCCCEEEECCH
RNYRAFREDVPEGKYTVDIGKGKKLREGEDVTVIAWGAMVPVAMKAAEAAAKKGIDADVI
HHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCEE
DLRTLYPLDKDMIAESVQKTGRTVIVQEAHATGGLANDILAVINDTSFFYQKAPAERVTG
HHHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHCCCHHHCCC
FDVPVPFFAHEDDYLPTPARVLHAIEKVMNDS
CCCCCCCEECCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2200674; 2253629 [H]