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The map label for this gene is yclF [H]

Identifier: 138895557

GI number: 138895557

Start: 2032326

End: 2033693

Strand: Reverse

Name: yclF [H]

Synonym: GTNG_1910

Alternate gene names: 138895557

Gene position: 2033693-2032326 (Counterclockwise)

Preceding gene: 138895558

Following gene: 138895556

Centisome position: 57.28

GC content: 50.37

Gene sequence:

>1368_bases
ATGAAGGCCATTTTAGTGTATTACATGTATTATGAAGTGTCGAAAGGTGGATTAGGACTCGACGAGCATTTGGCGCTTGC
GATTACGTCGATTTATGGTGCGCTTGTGTACATGTCGGGCATTATCGGCGGCTGGCTTGCCGACCGGGTGTTCGGAACAT
CAAAGGCAGTCTTTTATGGCGGCATTCTCATTATGGCCGGTCATATTGCGTTAGCGATCCCGGGTGGGGTGGCGGCACTG
TTTGTGTCGATGGCGCTCATCGTCCTTGGCACAGGGTTATTAAAACCGAACGTCTCCAGCATTGTTGGCGATATGTATCA
ACCGGGCGATGACCGCCGCGACGCTGGATTCAGCATTTTTTACATGGGCATTAACCTCGGGGCGTTTTTGGCTCCGCTTG
TCGTCGGCACGGCCGGCATGAAATACAACTTCCATCTTGGTTTCGGGCTCGCAGCTGTTGGAATGTTTCTTGGGCTTATT
GTATTTGTGGCGACAAGAAAGAAAAATCTCGGGTTGGCTGGGACGTATGTACCGAACCCGCTGACGCCAGCTGAAAAGAA
AAAAACGACTGTGATCGTTGCGGTTGCAGCGATTGTCATTGCTGTATTGCTTGCTATCTTGATTCCAAACGGTTGGTTTA
CCATTGAAACGTTTATTTCGCTTGTTGGTATTTTAGGTATCATCATTCCAACTATTTATTTTGTCGTGATGTACCGCAGC
CCGAAGACGACGGACGAAGAGCGGTCGCGCGTCATTGCTTACATACCGCTGTTTGTCGCTTCGGCGATGTTTTGGGCCAT
CCAAGAACAAGGTTCGACCATTTTGGCGAATTATGCCGATAAACGGACACAGTTGGATGTTGCTGGCATTCATCTTTCAC
CGGCTTGGTTCCAATCGCTGAACCCGTTGTTTATTATCACCTTAGCACCAGTATTCGCTTGGATGTGGGTGAAACTTGGT
AAACGGCAGCCGACGATTCCGCAAAAATTTGCTCTTGGTCTTTTGCTTGCTGGCCTGTCGTTTATCGTCATCCTTGTACC
AGGTTATTTCAGCGCCGGAGAACTCGTCCATCCGATTTGGCTTGTGTTGAGCTATTTCATCGTCGTGCTCGGTGAGCTTT
GTCTGTCGCCAGTCGGCCTGTCGGCAACGACGAAACTCGCCCCTGCGGCGTTTTCGGCGCAAACAATGAGCCTTTGGTTT
TTATCGAACGCTGCAGCGCAAGCGATCAACGCCCAACTCGTCCGTTTTTACACGCCGGAAAACGAAACGGCGTATTTCGG
CACGATCGGCGGGGCGGCCATCGTATTGAGTCTCATCTTATTCGCGCTAGCGCCAAGCATCCAGCGATTGATGAGAGGAG
TTCGTTAA

Upstream 100 bases:

>100_bases
AATCGCTGCCAGCGTTCCACAGCGAGGCTTTTTCGGCCATCCGAAAGGGCTGTTCACGCTCTTTTTTACAGAATTTTGGG
AGCGCTTCTCGTACTATGGC

Downstream 100 bases:

>100_bases
TCGCGATTGGATGATGGTTTGTCGTTACTTAGTGAAAAGAATGGAATTCAAAAGCAGGACGCTCTGCGTTAGCAGGGCGT
CTTTTTTTACCCTAAAAACT

Product: di-/tripeptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MKAILVYYMYYEVSKGGLGLDEHLALAITSIYGALVYMSGIIGGWLADRVFGTSKAVFYGGILIMAGHIALAIPGGVAAL
FVSMALIVLGTGLLKPNVSSIVGDMYQPGDDRRDAGFSIFYMGINLGAFLAPLVVGTAGMKYNFHLGFGLAAVGMFLGLI
VFVATRKKNLGLAGTYVPNPLTPAEKKKTTVIVAVAAIVIAVLLAILIPNGWFTIETFISLVGILGIIIPTIYFVVMYRS
PKTTDEERSRVIAYIPLFVASAMFWAIQEQGSTILANYADKRTQLDVAGIHLSPAWFQSLNPLFIITLAPVFAWMWVKLG
KRQPTIPQKFALGLLLAGLSFIVILVPGYFSAGELVHPIWLVLSYFIVVLGELCLSPVGLSATTKLAPAAFSAQTMSLWF
LSNAAAQAINAQLVRFYTPENETAYFGTIGGAAIVLSLILFALAPSIQRLMRGVR

Sequences:

>Translated_455_residues
MKAILVYYMYYEVSKGGLGLDEHLALAITSIYGALVYMSGIIGGWLADRVFGTSKAVFYGGILIMAGHIALAIPGGVAAL
FVSMALIVLGTGLLKPNVSSIVGDMYQPGDDRRDAGFSIFYMGINLGAFLAPLVVGTAGMKYNFHLGFGLAAVGMFLGLI
VFVATRKKNLGLAGTYVPNPLTPAEKKKTTVIVAVAAIVIAVLLAILIPNGWFTIETFISLVGILGIIIPTIYFVVMYRS
PKTTDEERSRVIAYIPLFVASAMFWAIQEQGSTILANYADKRTQLDVAGIHLSPAWFQSLNPLFIITLAPVFAWMWVKLG
KRQPTIPQKFALGLLLAGLSFIVILVPGYFSAGELVHPIWLVLSYFIVVLGELCLSPVGLSATTKLAPAAFSAQTMSLWF
LSNAAAQAINAQLVRFYTPENETAYFGTIGGAAIVLSLILFALAPSIQRLMRGVR
>Mature_455_residues
MKAILVYYMYYEVSKGGLGLDEHLALAITSIYGALVYMSGIIGGWLADRVFGTSKAVFYGGILIMAGHIALAIPGGVAAL
FVSMALIVLGTGLLKPNVSSIVGDMYQPGDDRRDAGFSIFYMGINLGAFLAPLVVGTAGMKYNFHLGFGLAAVGMFLGLI
VFVATRKKNLGLAGTYVPNPLTPAEKKKTTVIVAVAAIVIAVLLAILIPNGWFTIETFISLVGILGIIIPTIYFVVMYRS
PKTTDEERSRVIAYIPLFVASAMFWAIQEQGSTILANYADKRTQLDVAGIHLSPAWFQSLNPLFIITLAPVFAWMWVKLG
KRQPTIPQKFALGLLLAGLSFIVILVPGYFSAGELVHPIWLVLSYFIVVLGELCLSPVGLSATTKLAPAAFSAQTMSLWF
LSNAAAQAINAQLVRFYTPENETAYFGTIGGAAIVLSLILFALAPSIQRLMRGVR

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=397, Percent_Identity=25.6926952141058, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI226371746, Length=341, Percent_Identity=26.099706744868, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1790572, Length=398, Percent_Identity=29.3969849246231, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1786927, Length=397, Percent_Identity=32.4937027707809, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1787922, Length=450, Percent_Identity=27.7777777777778, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1789911, Length=455, Percent_Identity=25.4945054945055, Blast_Score=157, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI71987453, Length=367, Percent_Identity=26.158038147139, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24639585, Length=345, Percent_Identity=25.2173913043478, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24639583, Length=345, Percent_Identity=25.2173913043478, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24639581, Length=345, Percent_Identity=25.2173913043478, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28571098, Length=367, Percent_Identity=26.4305177111717, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 48907; Mature: 48907

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50850 MFS ; PS01022 PTR2_1 ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAILVYYMYYEVSKGGLGLDEHLALAITSIYGALVYMSGIIGGWLADRVFGTSKAVFYG
CCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
GILIMAGHIALAIPGGVAALFVSMALIVLGTGLLKPNVSSIVGDMYQPGDDRRDAGFSIF
HHHHHHCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCEEE
YMGINLGAFLAPLVVGTAGMKYNFHLGFGLAAVGMFLGLIVFVATRKKNLGLAGTYVPNP
EEHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCC
LTPAEKKKTTVIVAVAAIVIAVLLAILIPNGWFTIETFISLVGILGIIIPTIYFVVMYRS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECC
PKTTDEERSRVIAYIPLFVASAMFWAIQEQGSTILANYADKRTQLDVAGIHLSPAWFQSL
CCCCCHHHHHEEEHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEECHHHHHCC
NPLFIITLAPVFAWMWVKLGKRQPTIPQKFALGLLLAGLSFIVILVPGYFSAGELVHPIW
CCEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LVLSYFIVVLGELCLSPVGLSATTKLAPAAFSAQTMSLWFLSNAAAQAINAQLVRFYTPE
HHHHHHHHHHHHHHCCCCCCCCHHCCCCCHHCHHHHHHHHHHHHHHHHHHHEEEEEECCC
NETAYFGTIGGAAIVLSLILFALAPSIQRLMRGVR
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKAILVYYMYYEVSKGGLGLDEHLALAITSIYGALVYMSGIIGGWLADRVFGTSKAVFYG
CCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
GILIMAGHIALAIPGGVAALFVSMALIVLGTGLLKPNVSSIVGDMYQPGDDRRDAGFSIF
HHHHHHCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCEEE
YMGINLGAFLAPLVVGTAGMKYNFHLGFGLAAVGMFLGLIVFVATRKKNLGLAGTYVPNP
EEHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCC
LTPAEKKKTTVIVAVAAIVIAVLLAILIPNGWFTIETFISLVGILGIIIPTIYFVVMYRS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECC
PKTTDEERSRVIAYIPLFVASAMFWAIQEQGSTILANYADKRTQLDVAGIHLSPAWFQSL
CCCCCHHHHHEEEHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEECHHHHHCC
NPLFIITLAPVFAWMWVKLGKRQPTIPQKFALGLLLAGLSFIVILVPGYFSAGELVHPIW
CCEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LVLSYFIVVLGELCLSPVGLSATTKLAPAAFSAQTMSLWFLSNAAAQAINAQLVRFYTPE
HHHHHHHHHHHHHHCCCCCCCCHHCCCCCHHCHHHHHHHHHHHHHHHHHHHEEEEEECCC
NETAYFGTIGGAAIVLSLILFALAPSIQRLMRGVR
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]