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The map label for this gene is hexR [C]

Identifier: 138895529

GI number: 138895529

Start: 2005442

End: 2006299

Strand: Reverse

Name: hexR [C]

Synonym: GTNG_1879

Alternate gene names: 138895529

Gene position: 2006299-2005442 (Counterclockwise)

Preceding gene: 138895531

Following gene: 138895528

Centisome position: 56.51

GC content: 50.7

Gene sequence:

>858_bases
ATGAACGAAATCAGTATTTTAGCGAAAATTGAGCAGCAATTGGAACGGTTTTCGCCGGCGGAAAAAAAGGTTGCCCTCTA
TGTCCTCGACTATGCTGAGCTCGTGCCGAATATGACGACAAAAGAATTGGCGCAGGCGGCTGATACAAGCGAGGCGAGCG
TCACCCGCTTTTGCAAGGCGGTCGGTATCGGCAGTTTTCCAGGACTGAAGTTGGCACTTGTCCGCGAGTTGACGATGGCG
GATATGAACATTAATGATTTTTCCATCATTGACAAACCGAATGCGCCGTATGAGCTGTTTATGAAAGTGACCTATGTGAA
TAAGGCGGCCATTGAGGCGACAACGACAACACTCGATAAGCGCGAGTTGGAAAAAGCTGCTGAGGCGATGATGAAAGCCG
AGAGGGTGGTGTTTTATGGAGTCGGCGGTTCTGCAGCTGCAGCGGTGGACGCTAGTTATAAGTTTACGAAGCTTGGCTAC
ATGGCGGCAACGTCGCCTGATTTTCATACGATGCTGCCACTGGTGGCCCATTTGAAAGAAGGAGATGTGTTCGTGGCCAT
ATCGACGTCAGGGCGGACGAAAGATGTATTGGAGATCGCCCGGTTTGCAAAAAAGCAACAGGCGACGGTCATTGCCATTA
CAAAGCTTGATCCGGCCTCGCCGTTATATAAGGAAGCGGATATTCGGCTTGCGCTGCCGGATGTCGAGCAAGACCATCGC
ATCGGCAGTATGGCATCGAGAATGGTGCAGCTCAACGTGATCGATGCGCTCTATTTAATCATGTTCCATCGTGTGGGGAG
CCGAGTCATTGAACGATTTCACCAGACAAGAGAAGAAGTGGTGCGGTTGCGAAGGTAA

Upstream 100 bases:

>100_bases
TTTTATGTTTGCGAGAAATAAGAAAAAGCCGGCACGTGGAGAACAAGAGTTATCCATGATAAGATGAGAATAAAAATGGC
TAGCGGGAAAGGAGAAAACG

Downstream 100 bases:

>100_bases
AGCGGGCTTGAGGCGAGCCCGCTTTTTTTGTAGGAATGTTTCAAATGAAAAAAGAATAGATTGATATTTTATTTCATAAA
TTTATAATATAATTATGAAA

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MNEISILAKIEQQLERFSPAEKKVALYVLDYAELVPNMTTKELAQAADTSEASVTRFCKAVGIGSFPGLKLALVRELTMA
DMNINDFSIIDKPNAPYELFMKVTYVNKAAIEATTTTLDKRELEKAAEAMMKAERVVFYGVGGSAAAAVDASYKFTKLGY
MAATSPDFHTMLPLVAHLKEGDVFVAISTSGRTKDVLEIARFAKKQQATVIAITKLDPASPLYKEADIRLALPDVEQDHR
IGSMASRMVQLNVIDALYLIMFHRVGSRVIERFHQTREEVVRLRR

Sequences:

>Translated_285_residues
MNEISILAKIEQQLERFSPAEKKVALYVLDYAELVPNMTTKELAQAADTSEASVTRFCKAVGIGSFPGLKLALVRELTMA
DMNINDFSIIDKPNAPYELFMKVTYVNKAAIEATTTTLDKRELEKAAEAMMKAERVVFYGVGGSAAAAVDASYKFTKLGY
MAATSPDFHTMLPLVAHLKEGDVFVAISTSGRTKDVLEIARFAKKQQATVIAITKLDPASPLYKEADIRLALPDVEQDHR
IGSMASRMVQLNVIDALYLIMFHRVGSRVIERFHQTREEVVRLRR
>Mature_285_residues
MNEISILAKIEQQLERFSPAEKKVALYVLDYAELVPNMTTKELAQAADTSEASVTRFCKAVGIGSFPGLKLALVRELTMA
DMNINDFSIIDKPNAPYELFMKVTYVNKAAIEATTTTLDKRELEKAAEAMMKAERVVFYGVGGSAAAAVDASYKFTKLGY
MAATSPDFHTMLPLVAHLKEGDVFVAISTSGRTKDVLEIARFAKKQQATVIAITKLDPASPLYKEADIRLALPDVEQDHR
IGSMASRMVQLNVIDALYLIMFHRVGSRVIERFHQTREEVVRLRR

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=281, Percent_Identity=32.0284697508897, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788767, Length=274, Percent_Identity=31.7518248175182, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87082369, Length=258, Percent_Identity=27.906976744186, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87082130, Length=288, Percent_Identity=25.3472222222222, Blast_Score=85, Evalue=5e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31696; Mature: 31696

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEISILAKIEQQLERFSPAEKKVALYVLDYAELVPNMTTKELAQAADTSEASVTRFCKA
CCCHHHHHHHHHHHHHCCCCHHEEEEEEEEHHHHCCCCCHHHHHHHCCCCHHHHHHHHHH
VGIGSFPGLKLALVRELTMADMNINDFSIIDKPNAPYELFMKVTYVNKAAIEATTTTLDK
HCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHEEEEEECCHHHHHHHHHHHHH
RELEKAAEAMMKAERVVFYGVGGSAAAAVDASYKFTKLGYMAATSPDFHTMLPLVAHLKE
HHHHHHHHHHHHHCEEEEEECCCCCHHHCCCCCEEHEECEEEECCCCHHHHHHHHHHCCC
GDVFVAISTSGRTKDVLEIARFAKKQQATVIAITKLDPASPLYKEADIRLALPDVEQDHR
CCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHCCCCEEECCCCCCHHH
IGSMASRMVQLNVIDALYLIMFHRVGSRVIERFHQTREEVVRLRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNEISILAKIEQQLERFSPAEKKVALYVLDYAELVPNMTTKELAQAADTSEASVTRFCKA
CCCHHHHHHHHHHHHHCCCCHHEEEEEEEEHHHHCCCCCHHHHHHHCCCCHHHHHHHHHH
VGIGSFPGLKLALVRELTMADMNINDFSIIDKPNAPYELFMKVTYVNKAAIEATTTTLDK
HCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHEEEEEECCHHHHHHHHHHHHH
RELEKAAEAMMKAERVVFYGVGGSAAAAVDASYKFTKLGYMAATSPDFHTMLPLVAHLKE
HHHHHHHHHHHHHCEEEEEECCCCCHHHCCCCCEEHEECEEEECCCCHHHHHHHHHHCCC
GDVFVAISTSGRTKDVLEIARFAKKQQATVIAITKLDPASPLYKEADIRLALPDVEQDHR
CCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHCCCCEEECCCCCCHHH
IGSMASRMVQLNVIDALYLIMFHRVGSRVIERFHQTREEVVRLRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]