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The map label for this gene is ilvD [H]

Identifier: 138895520

GI number: 138895520

Start: 1992442

End: 1994643

Strand: Reverse

Name: ilvD [H]

Synonym: GTNG_1868

Alternate gene names: 138895520

Gene position: 1994643-1992442 (Counterclockwise)

Preceding gene: 138895521

Following gene: 138895519

Centisome position: 56.18

GC content: 50.68

Gene sequence:

>2202_bases
ATGGCGGCGGTTGTTTATCCACGTATTGAAAGCCAGATCAACCCATACCGCGATAATGTTCAAGGGAAGGCGAATGAGCC
AATATGTGTAGCCGGATTGCTCGACCGTTCAAAACAAATTTTAGGTTCCGAGTTAAAAGGGATGCAGCCAGACTGGACGT
TAGAGGAAATCTACGATCGGCTGCACCACAACGCCCCCCGGATTGCGATCATAGGGGGATCGCCGGACCATCCCGCGCAC
ATCATGGATTTTCAAACGATTGCCCGGGCAGCCATTCGGATTTGGCAAAACGGGGGAGTGCCGTTTCAGTTTTCGACACC
GGTCATGTGCGACGGAACGGCGCAGAGCAACCAGGGAATGAGCTATTCGCTGCAAAGTCGCAATGCGGTGGCGCAAATGA
TCGTGAACCAGTTGGAAGCCCATAGCTACCACGGTGCTTTTGTCATTCAAGGATGCGACAAGCAGCCGCTCGGCGTCGTC
AGCGCTTTGGCACATCTTGACCGTGTCCGTCGGGAGCGAGGAGAGGCGCCTTTCTTCGCCACCTTTGCGCCATCCCATGT
ATTACAAGGAGGAACGATCCCACCCAAGTTGTATGCCGAACTGGAGGAAGTCGCCCGACGGGCGGAATTAGCTGGGGAAG
AAGACATCGCGTATGATTTGCGGGATGCACTGGCATATATTTTACAATGTTCTTCCAACACAGCTTTTCAAGGAGTGCTC
GAGCGGGCGAGAGGAAAAGGAATCATTACAAAAGAGCAGCACGAAGACTATGAAAAACGATTGGCTGTAGCGACATGTGA
CAGCCAGGGCGGCGTTTGCGCCTTTAACGGAACCGGCAACAGCTCTCGGCATTTAATCGCCGGATTAGGCTTGGTCCATC
CTGCTTTGGAACTGTTGACGGCCCCGCCGACACAAGAACAGATTAACGCGGCCCTCGACAGCTTTGTCGATTTAATGAAT
GATCCGGTGTATGGTGTGGCCAATCTTATGGCGGCCAATATTAAAAACGCGATTCGCATTCATAGCGCCACCGGCGGATC
AACGAACATTATGATGCATATTGTGGCAGCCATGCTGTATGGGGGATATCGGTTCGATTTGTGGGAGTACGACCGCATCC
ACCATGAAGTACCGGTTCCTGATTTGTTTGACTACAGTTTAACTGAGGGAAGAGATATTTTCGCGTTGGCGGTTCAATGC
TGCAGCGGGAAAATAAGGGGAATGGAAACCGTATTCCATGAATTAATGAGCAATGGGGTGCCGATGGATATCGATGCCCC
AACTGTCACCGGGACGACTTGGCGGGAAAGACTCGCCGTCAATCAAGCGCAGTTGTCAGCCGAGAACGTCGAAAACAACC
CGATCATTTTGTCCAAGCCGAGACGGCCGTTTAGCGGCGTCGACGTTCTATCAGGGAACTTCTTTGAAAGTGCGGTCGTG
AAAATCAGCGGTATGTCGACAAAACAAATTGATGAATTTGACAAGAAAATTGCCTTTGTCCTGTATTATGAAAACGAGGA
TGAGGCGAATGAGGGGCTGCTCGATGTTCACTTGCTTGAAAAGTTGAAACGGAGCCGTTGCTTCCGTCATCAAAGCTTGA
TCGCTGCATTGAAACATAATGCCCCGCATTGGTTTGAGGAGTGGAAACATCGTGAATATGATGATTTGTTTGATGCGATG
GTGAAAGAAGGGGCGTTAAAAATCGCAGTAGTCATCGCTGGCCAAGGACCGGAAGCGTTCGGCATGCCAGAAATGTTCAC
CCCGATGCAGCATATTAATGCGAACCGCCAGTTAAAACGGCTTGCCACTCTGATCAGTGACGGGCGTTACTCCGGTGTCA
CATATGGGGCGGCTATCGGGCACATGACTCCCGAAGCGATTCGCGGGGGAGGGATTTTGTACTTAAAGACAGGAGATCTC
CTATATATTGGCCTTCGCGAACGGAAAATCGAATTCGTCAATGAAGGGGCGTTCCAACATGGGAAACTTGTATTCGAGTT
TGAAGGGGTGAAACAGGAAAGAGAAGAAATCGCCAATCAACGCATGGCCAACATGCGTCAACGTCAACGGCGCATTGCAG
CAAGCAACCGGCTAATCGGACATACCGACGCTGCCCATGGCGTTGTTCCGCTCCACATTGCCGAAGAGGCGGTATATGAT
TACAAAAAGGATATCATTCTTCCAACAGTGAAAAAATCATAA

Upstream 100 bases:

>100_bases
TTTTAGATGAGGCATATCGAACAGAAGGAATTGAGATTTTATCAGCGCCAATGGCGATGGACTTTTCAAATTAAATCATA
TGGGGCGAGGAGGATTTGAA

Downstream 100 bases:

>100_bases
CGGGTGGACCGAAGTGATTCGAGCTTTTCACCCTCCTGTATTATAATAGAACCAAGGCAAATTCCCTGATTGCATAGTCC
GCAAAACTTCTAGAAAAGAG

Product: dihydroxy-acid dehydratase

Products: NA

Alternate protein names: DAD [H]

Number of amino acids: Translated: 733; Mature: 732

Protein sequence:

>733_residues
MAAVVYPRIESQINPYRDNVQGKANEPICVAGLLDRSKQILGSELKGMQPDWTLEEIYDRLHHNAPRIAIIGGSPDHPAH
IMDFQTIARAAIRIWQNGGVPFQFSTPVMCDGTAQSNQGMSYSLQSRNAVAQMIVNQLEAHSYHGAFVIQGCDKQPLGVV
SALAHLDRVRRERGEAPFFATFAPSHVLQGGTIPPKLYAELEEVARRAELAGEEDIAYDLRDALAYILQCSSNTAFQGVL
ERARGKGIITKEQHEDYEKRLAVATCDSQGGVCAFNGTGNSSRHLIAGLGLVHPALELLTAPPTQEQINAALDSFVDLMN
DPVYGVANLMAANIKNAIRIHSATGGSTNIMMHIVAAMLYGGYRFDLWEYDRIHHEVPVPDLFDYSLTEGRDIFALAVQC
CSGKIRGMETVFHELMSNGVPMDIDAPTVTGTTWRERLAVNQAQLSAENVENNPIILSKPRRPFSGVDVLSGNFFESAVV
KISGMSTKQIDEFDKKIAFVLYYENEDEANEGLLDVHLLEKLKRSRCFRHQSLIAALKHNAPHWFEEWKHREYDDLFDAM
VKEGALKIAVVIAGQGPEAFGMPEMFTPMQHINANRQLKRLATLISDGRYSGVTYGAAIGHMTPEAIRGGGILYLKTGDL
LYIGLRERKIEFVNEGAFQHGKLVFEFEGVKQEREEIANQRMANMRQRQRRIAASNRLIGHTDAAHGVVPLHIAEEAVYD
YKKDIILPTVKKS

Sequences:

>Translated_733_residues
MAAVVYPRIESQINPYRDNVQGKANEPICVAGLLDRSKQILGSELKGMQPDWTLEEIYDRLHHNAPRIAIIGGSPDHPAH
IMDFQTIARAAIRIWQNGGVPFQFSTPVMCDGTAQSNQGMSYSLQSRNAVAQMIVNQLEAHSYHGAFVIQGCDKQPLGVV
SALAHLDRVRRERGEAPFFATFAPSHVLQGGTIPPKLYAELEEVARRAELAGEEDIAYDLRDALAYILQCSSNTAFQGVL
ERARGKGIITKEQHEDYEKRLAVATCDSQGGVCAFNGTGNSSRHLIAGLGLVHPALELLTAPPTQEQINAALDSFVDLMN
DPVYGVANLMAANIKNAIRIHSATGGSTNIMMHIVAAMLYGGYRFDLWEYDRIHHEVPVPDLFDYSLTEGRDIFALAVQC
CSGKIRGMETVFHELMSNGVPMDIDAPTVTGTTWRERLAVNQAQLSAENVENNPIILSKPRRPFSGVDVLSGNFFESAVV
KISGMSTKQIDEFDKKIAFVLYYENEDEANEGLLDVHLLEKLKRSRCFRHQSLIAALKHNAPHWFEEWKHREYDDLFDAM
VKEGALKIAVVIAGQGPEAFGMPEMFTPMQHINANRQLKRLATLISDGRYSGVTYGAAIGHMTPEAIRGGGILYLKTGDL
LYIGLRERKIEFVNEGAFQHGKLVFEFEGVKQEREEIANQRMANMRQRQRRIAASNRLIGHTDAAHGVVPLHIAEEAVYD
YKKDIILPTVKKS
>Mature_732_residues
AAVVYPRIESQINPYRDNVQGKANEPICVAGLLDRSKQILGSELKGMQPDWTLEEIYDRLHHNAPRIAIIGGSPDHPAHI
MDFQTIARAAIRIWQNGGVPFQFSTPVMCDGTAQSNQGMSYSLQSRNAVAQMIVNQLEAHSYHGAFVIQGCDKQPLGVVS
ALAHLDRVRRERGEAPFFATFAPSHVLQGGTIPPKLYAELEEVARRAELAGEEDIAYDLRDALAYILQCSSNTAFQGVLE
RARGKGIITKEQHEDYEKRLAVATCDSQGGVCAFNGTGNSSRHLIAGLGLVHPALELLTAPPTQEQINAALDSFVDLMND
PVYGVANLMAANIKNAIRIHSATGGSTNIMMHIVAAMLYGGYRFDLWEYDRIHHEVPVPDLFDYSLTEGRDIFALAVQCC
SGKIRGMETVFHELMSNGVPMDIDAPTVTGTTWRERLAVNQAQLSAENVENNPIILSKPRRPFSGVDVLSGNFFESAVVK
ISGMSTKQIDEFDKKIAFVLYYENEDEANEGLLDVHLLEKLKRSRCFRHQSLIAALKHNAPHWFEEWKHREYDDLFDAMV
KEGALKIAVVIAGQGPEAFGMPEMFTPMQHINANRQLKRLATLISDGRYSGVTYGAAIGHMTPEAIRGGGILYLKTGDLL
YIGLRERKIEFVNEGAFQHGKLVFEFEGVKQEREEIANQRMANMRQRQRRIAASNRLIGHTDAAHGVVPLHIAEEAVYDY
KKDIILPTVKKS

Specific function: Unknown

COG id: COG0129

COG function: function code EG; Dihydroxyacid dehydratase/phosphogluconate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ilvD/edd family [H]

Homologues:

Organism=Escherichia coli, GI2367371, Length=591, Percent_Identity=26.2267343485618, Blast_Score=112, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015928
- InterPro:   IPR004404
- InterPro:   IPR000581
- InterPro:   IPR020558 [H]

Pfam domain/function: PF00920 ILVD_EDD [H]

EC number: =4.2.1.9 [H]

Molecular weight: Translated: 81428; Mature: 81297

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAVVYPRIESQINPYRDNVQGKANEPICVAGLLDRSKQILGSELKGMQPDWTLEEIYDR
CCEEECCCHHHCCCCHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
LHHNAPRIAIIGGSPDHPAHIMDFQTIARAAIRIWQNGGVPFQFSTPVMCDGTAQSNQGM
HHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCEEECCCCCCCCCC
SYSLQSRNAVAQMIVNQLEAHSYHGAFVIQGCDKQPLGVVSALAHLDRVRRERGEAPFFA
EEEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEE
TFAPSHVLQGGTIPPKLYAELEEVARRAELAGEEDIAYDLRDALAYILQCSSNTAFQGVL
ECCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
ERARGKGIITKEQHEDYEKRLAVATCDSQGGVCAFNGTGNSSRHLIAGLGLVHPALELLT
HHHCCCCCCCCHHHHHHHHHEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHC
APPTQEQINAALDSFVDLMNDPVYGVANLMAANIKNAIRIHSATGGSTNIMMHIVAAMLY
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHH
GGYRFDLWEYDRIHHEVPVPDLFDYSLTEGRDIFALAVQCCSGKIRGMETVFHELMSNGV
CCEEECCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
PMDIDAPTVTGTTWRERLAVNQAQLSAENVENNPIILSKPRRPFSGVDVLSGNFFESAVV
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHEEE
KISGMSTKQIDEFDKKIAFVLYYENEDEANEGLLDVHLLEKLKRSRCFRHQSLIAALKHN
EEECCCHHHHHHHCCCEEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCC
APHWFEEWKHREYDDLFDAMVKEGALKIAVVIAGQGPEAFGMPEMFTPMQHINANRQLKR
CCHHHHHHCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHCCHHHHCCHHHHHH
LATLISDGRYSGVTYGAAIGHMTPEAIRGGGILYLKTGDLLYIGLRERKIEFVNEGAFQH
HHHHHHCCCCCCEEEHHHHCCCCHHHHCCCCEEEEEECCEEEEECHHHHHHHHHCCCCCC
GKLVFEFEGVKQEREEIANQRMANMRQRQRRIAASNRLIGHTDAAHGVVPLHIAEEAVYD
CCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHH
YKKDIILPTVKKS
HHCCCCCCCCCCC
>Mature Secondary Structure 
AAVVYPRIESQINPYRDNVQGKANEPICVAGLLDRSKQILGSELKGMQPDWTLEEIYDR
CEEECCCHHHCCCCHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
LHHNAPRIAIIGGSPDHPAHIMDFQTIARAAIRIWQNGGVPFQFSTPVMCDGTAQSNQGM
HHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCEEECCCCCCCCCC
SYSLQSRNAVAQMIVNQLEAHSYHGAFVIQGCDKQPLGVVSALAHLDRVRRERGEAPFFA
EEEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEE
TFAPSHVLQGGTIPPKLYAELEEVARRAELAGEEDIAYDLRDALAYILQCSSNTAFQGVL
ECCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
ERARGKGIITKEQHEDYEKRLAVATCDSQGGVCAFNGTGNSSRHLIAGLGLVHPALELLT
HHHCCCCCCCCHHHHHHHHHEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHC
APPTQEQINAALDSFVDLMNDPVYGVANLMAANIKNAIRIHSATGGSTNIMMHIVAAMLY
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHH
GGYRFDLWEYDRIHHEVPVPDLFDYSLTEGRDIFALAVQCCSGKIRGMETVFHELMSNGV
CCEEECCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
PMDIDAPTVTGTTWRERLAVNQAQLSAENVENNPIILSKPRRPFSGVDVLSGNFFESAVV
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHEEE
KISGMSTKQIDEFDKKIAFVLYYENEDEANEGLLDVHLLEKLKRSRCFRHQSLIAALKHN
EEECCCHHHHHHHCCCEEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCC
APHWFEEWKHREYDDLFDAMVKEGALKIAVVIAGQGPEAFGMPEMFTPMQHINANRQLKR
CCHHHHHHCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHCCHHHHCCHHHHHH
LATLISDGRYSGVTYGAAIGHMTPEAIRGGGILYLKTGDLLYIGLRERKIEFVNEGAFQH
HHHHHHCCCCCCEEEHHHHCCCCHHHHCCCCEEEEEECCEEEEECHHHHHHHHHCCCCCC
GKLVFEFEGVKQEREEIANQRMANMRQRQRRIAASNRLIGHTDAAHGVVPLHIAEEAVYD
CCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHH
YKKDIILPTVKKS
HHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA