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The map label for this gene is dgoD1 [H]

Identifier: 138895507

GI number: 138895507

Start: 1979876

End: 1980808

Strand: Reverse

Name: dgoD1 [H]

Synonym: GTNG_1855

Alternate gene names: 138895507

Gene position: 1980808-1979876 (Counterclockwise)

Preceding gene: 138895508

Following gene: 138895506

Centisome position: 55.79

GC content: 48.66

Gene sequence:

>933_bases
GTGAAGATTACGAAGTTCGAGACTTTTCTTGTCCCACCTCGATGGTTGTTCCTAAAAATCAGTACGGATGAAGGAATTGC
TGGATGGGGTGAACCGATTGTTGAAGGGAGAGCCAATACTGTACGAGCGGCAGTAGAGGAGCTAGGCGATTATTTAATCG
GAAAGGATCCATTAGCGATTGAGGATCATTGGACCGTCCTTTACCGGGGGGGATTTTACCGTGGGGGCCCTGTTTTAATG
AGCGCCATCTCTGGGATTGACCAAGCGCTTTGGGATATCAAAGGGAAATACTTCAATGCCCCGGTTCATCAACTGCTCGG
CGGCCCGGTTCGCCATTCCATTCGGGTTTACAGCTGGATTGGCGGCGATCGCCCAAGCGACGTTGCCGAGGCAGCAAAAA
AAGCGAAAGAAGCAGGATTTACAGCGGTGAAAATGAATGCGACCGAGGAGCTTCAATATATTGATTCTTATAAAAAGATT
GACGAAACGGTTGAAAGGGTGGCTGCAGTGCGCCAAGTGGTGGGCAAAGAGTTCGGGATTGGCATCGATTTTCACGGACG
CGTTCATAAACCAATGGCAAAAATTTTGGCAAAAGAGCTTGAACCGTATCATCCGCTGTTTATCGAAGAACCTGTATTGC
CAGAACATAATGAAGCATTAAAGGAGATCGCCAAGCACACCACTATCCCCATTGCCACCGGAGAACGGATGTTTTCCCGT
TGGGATTTTAAAACGATTTTATCCGAGGGCTATGTTGATATGATTCAGCCGGACCTTTCCCATGCTGGCGGAATTACTGA
AGTGAGAAAAATTGCCGTGATGGCTGAGGCCTACGACGTCGCTTTGGCACCGCACTGCCCGTTGGGGCCGATTGCGTTAG
CAGCCTCTTTGCAGGTCGATGCCGTATCTTATAACGCGTTTATTCAAGAATAA

Upstream 100 bases:

>100_bases
CGGGTCATTGAGGAAGGGAGATTCAACCTTCTTACAGAAACGGCAAAGAGATTTGTCGAAACGGTTAGAAACGCAGCCGT
AAGAGAGGGGGAATAGGAAC

Downstream 100 bases:

>100_bases
AGCCTTGGCATTCACTACAACCAAGGAAATGATCTCCTTGATTATTTAGTGGATCCTTCCGTCTTTGAATATCAAAATGG
ATATGTCAAAATCCCGCAAG

Product: galactonate dehydratase protein

Products: NA

Alternate protein names: GalD 1 [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKITKFETFLVPPRWLFLKISTDEGIAGWGEPIVEGRANTVRAAVEELGDYLIGKDPLAIEDHWTVLYRGGFYRGGPVLM
SAISGIDQALWDIKGKYFNAPVHQLLGGPVRHSIRVYSWIGGDRPSDVAEAAKKAKEAGFTAVKMNATEELQYIDSYKKI
DETVERVAAVRQVVGKEFGIGIDFHGRVHKPMAKILAKELEPYHPLFIEEPVLPEHNEALKEIAKHTTIPIATGERMFSR
WDFKTILSEGYVDMIQPDLSHAGGITEVRKIAVMAEAYDVALAPHCPLGPIALAASLQVDAVSYNAFIQE

Sequences:

>Translated_310_residues
MKITKFETFLVPPRWLFLKISTDEGIAGWGEPIVEGRANTVRAAVEELGDYLIGKDPLAIEDHWTVLYRGGFYRGGPVLM
SAISGIDQALWDIKGKYFNAPVHQLLGGPVRHSIRVYSWIGGDRPSDVAEAAKKAKEAGFTAVKMNATEELQYIDSYKKI
DETVERVAAVRQVVGKEFGIGIDFHGRVHKPMAKILAKELEPYHPLFIEEPVLPEHNEALKEIAKHTTIPIATGERMFSR
WDFKTILSEGYVDMIQPDLSHAGGITEVRKIAVMAEAYDVALAPHCPLGPIALAASLQVDAVSYNAFIQE
>Mature_310_residues
MKITKFETFLVPPRWLFLKISTDEGIAGWGEPIVEGRANTVRAAVEELGDYLIGKDPLAIEDHWTVLYRGGFYRGGPVLM
SAISGIDQALWDIKGKYFNAPVHQLLGGPVRHSIRVYSWIGGDRPSDVAEAAKKAKEAGFTAVKMNATEELQYIDSYKKI
DETVERVAAVRQVVGKEFGIGIDFHGRVHKPMAKILAKELEPYHPLFIEEPVLPEHNEALKEIAKHTTIPIATGERMFSR
WDFKTILSEGYVDMIQPDLSHAGGITEVRKIAVMAEAYDVALAPHCPLGPIALAASLQVDAVSYNAFIQE

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994953, Length=310, Percent_Identity=64.8387096774194, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI1787864, Length=341, Percent_Identity=35.4838709677419, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI226510960, Length=217, Percent_Identity=32.7188940092166, Blast_Score=98, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 34366; Mature: 34366

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00908 MR_MLE_1 ; PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITKFETFLVPPRWLFLKISTDEGIAGWGEPIVEGRANTVRAAVEELGDYLIGKDPLAI
CCCCCEEEEECCCCEEEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCEEE
EDHWTVLYRGGFYRGGPVLMSAISGIDQALWDIKGKYFNAPVHQLLGGPVRHSIRVYSWI
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHEEEEEEC
GGDRPSDVAEAAKKAKEAGFTAVKMNATEELQYIDSYKKIDETVERVAAVRQVVGKEFGI
CCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GIDFHGRVHKPMAKILAKELEPYHPLFIEEPVLPEHNEALKEIAKHTTIPIATGERMFSR
CCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCEECCHHHHHH
WDFKTILSEGYVDMIQPDLSHAGGITEVRKIAVMAEAYDVALAPHCPLGPIALAASLQVD
HHHHHHHHCCCHHHHCCCHHHCCCHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHCEEE
AVSYNAFIQE
EEEHHHEECC
>Mature Secondary Structure
MKITKFETFLVPPRWLFLKISTDEGIAGWGEPIVEGRANTVRAAVEELGDYLIGKDPLAI
CCCCCEEEEECCCCEEEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCEEE
EDHWTVLYRGGFYRGGPVLMSAISGIDQALWDIKGKYFNAPVHQLLGGPVRHSIRVYSWI
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHEEEEEEC
GGDRPSDVAEAAKKAKEAGFTAVKMNATEELQYIDSYKKIDETVERVAAVRQVVGKEFGI
CCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GIDFHGRVHKPMAKILAKELEPYHPLFIEEPVLPEHNEALKEIAKHTTIPIATGERMFSR
CCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCEECCHHHHHH
WDFKTILSEGYVDMIQPDLSHAGGITEVRKIAVMAEAYDVALAPHCPLGPIALAASLQVD
HHHHHHHHCCCHHHHCCCHHHCCCHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHCEEE
AVSYNAFIQE
EEEHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA