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The map label for this gene is mtlR [H]

Identifier: 138895498

GI number: 138895498

Start: 1967327

End: 1969276

Strand: Reverse

Name: mtlR [H]

Synonym: GTNG_1846

Alternate gene names: 138895498

Gene position: 1969276-1967327 (Counterclockwise)

Preceding gene: 138895499

Following gene: 138895497

Centisome position: 55.47

GC content: 53.23

Gene sequence:

>1950_bases
TTGCGGCACTACGGACTTGAGCTGGTGAAAAAAGCAGGGGTCGGCATTCGTCTCGTTGGGGAAGAGAAACAAAAGCAGGC
GCTGGCTGCCGAGCTGCTTCATCTTTCTCACCGTGAATATACGCCGGAAGAACGGCAGCTGATGATTTTAATCGCCTTGT
TAGAAGCCGGTGAGCCAGTGAAACTCGTCTCACTGGCGAACGACTTGAACGTCACGGTTGCCACTGTCAGTTTGGATTTG
GACAAATTGGAACAAACGCTCAAAGCGTACGGGCTTTCGCTCATTCGCAAGCGCGGGTACGGGGTGGAGCTTGCCGGTTC
CGAATCAGCGAAACGGCGTCTCATTAGCGAACTGCTATTCCGCCATGTCAATGAACACGAGTTTTTGGAGCTGATGAAAG
AGACGATTCAGAAGCGGTCAGATGATCCGCTTGATACGGTGGCGGAAAAGCTGCTCGGGCTTGTGGATCGAAAAAAGCTC
GCCATCATTGAGAAACAAATCGAGCAAGTAAAAGAAAAGCTCCCATTTACGATGGCGGACAGTTCGTACATCGCCTTCGT
CGTCCATTTGGCGCTCGCCATCGAGCGCATCAAGCGGGGGGAAGCGATTCATTTCGACCCGCACGATTTGCGGACGCTCC
AGGCAGCGAAAGAATTTGCGATCGCCGAAATGCTCGCTGAATCGTTGGAAAGAGCTTTTGGCATTAACATTCCAAAAGAA
GAAATCGGCTATATGACGATGCATTTAATGGGAGCGAAATGGCGCAGCCGTCAAGGAATGATGATGGAGGAGCCGAGTTT
GGTTGTCGGCATGAAAGCGCAACAGCTCATTCGTTTCGTCAGCCGTGAGCTTGGAGTCGATCTGTCCACCGACCGCACGC
TATACGAAGATCTCGTCGTTCACTTAAAACCGGCGTTGTACCGTTTAGAGCACGGGATGGGGGTCGCCAATCCGCTCCTG
GATCAAATTAGGAAAGACTATCCGGAGCTGTTTGCGGTTGTCGCCAATGGAACGAAGCAGCTGTTTGGCTACATTCCGGT
GCCAGAGGAGGAGATCGGTTACTTGGTGCTCCATTTTGCGGCTGCGCTCATGCGGGAGAAAAAAGGTTGGCGGGCGCTCG
TTATTTGTTCGAGCGGGCTCGGAACGGCGAAAATTTTAGCGACAAGGCTGAAAAGAGCGATTCCGGATATCACTGTCATG
GAGCAGGCGTCTGTCTTTGAATTGAAAAAGAAAGATTTGCGGGCGTACGACCTCGTCATTTCGACCGTGCCGCTTCCGGA
AGAGTACGGGCCGCATGTCATCGTCAGTCCAATGCTCACCGAAGAGGAAGCGCGGGCGATCCGCCAGCGGTTGGAACGGA
AAACAGCTGTGGAAAAGCGGAGGGAAAACGAGTCCATTGCACGTCGAAATCGGTCGATGCTCGCCACGATGAAAGCCGTT
CGACGCATCAGTGAGACGATCATCCATCTTTTGGACGGTTTTCTCCTTGAGATGGTCACTTGTCGTTCGATCCATGAATT
ATTGATGAACGCGTGCCGTCGCCTCGAGCGAAACGGGGTTCTTGTCGATGCCAAAGTCGTCATCGAGGAGCTGGAGCGCC
GCGAGTCGCTAGGCGGGCTCGGCGTTCCCGGCACGAAGCTGGCGCTTTACCACGCCCGCAGTTTCTCTGTCCTTCGTCCA
TCGCTGACGATGTACCGGCTTGATGAACCACAAACGGTGGCAGGCATGGACGGGGAGCCGATGGAAGTAAACACGGTTGT
ACTGCTTCTTGGCCCTGCCGATGCGGATGAAGAGATGCTTTCCGTATTGAGCCAAGTGAGCACTTTGCTCGTCAAGGACG
AACAAAGCACGGCCACGTTGGCTCGTGGCGGCGAAAACGAGGTATATTCGCTCGTTAGCAGCCATTTAGAACAATTTTTC
GATCATTATTGGACAACAACGAAGGAGTGA

Upstream 100 bases:

>100_bases
GTTAGTAGGAGGGCGAGAGATAACAGTCGGCGAGCTGGCCGAAGAGCTGAATGTCAGCACCCGCACGATCCACCGCGATT
TGCAAGGCCTCGAATCCGTT

Downstream 100 bases:

>100_bases
AGGTCATGTTGGCTTATTCAATTTTAAAGAAAGAAAACATTGTGCTAAATGCTCAACCAAAAACGAAAGAAGAAGCCATT
CGCCTAGCTGGCGAAGTGCT

Product: putative transcriptional regulator

Products: NA

Alternate protein names: Mannitol operon transcriptional activator; Mtl operon transcriptional activator; Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 649; Mature: 649

Protein sequence:

>649_residues
MRHYGLELVKKAGVGIRLVGEEKQKQALAAELLHLSHREYTPEERQLMILIALLEAGEPVKLVSLANDLNVTVATVSLDL
DKLEQTLKAYGLSLIRKRGYGVELAGSESAKRRLISELLFRHVNEHEFLELMKETIQKRSDDPLDTVAEKLLGLVDRKKL
AIIEKQIEQVKEKLPFTMADSSYIAFVVHLALAIERIKRGEAIHFDPHDLRTLQAAKEFAIAEMLAESLERAFGINIPKE
EIGYMTMHLMGAKWRSRQGMMMEEPSLVVGMKAQQLIRFVSRELGVDLSTDRTLYEDLVVHLKPALYRLEHGMGVANPLL
DQIRKDYPELFAVVANGTKQLFGYIPVPEEEIGYLVLHFAAALMREKKGWRALVICSSGLGTAKILATRLKRAIPDITVM
EQASVFELKKKDLRAYDLVISTVPLPEEYGPHVIVSPMLTEEEARAIRQRLERKTAVEKRRENESIARRNRSMLATMKAV
RRISETIIHLLDGFLLEMVTCRSIHELLMNACRRLERNGVLVDAKVVIEELERRESLGGLGVPGTKLALYHARSFSVLRP
SLTMYRLDEPQTVAGMDGEPMEVNTVVLLLGPADADEEMLSVLSQVSTLLVKDEQSTATLARGGENEVYSLVSSHLEQFF
DHYWTTTKE

Sequences:

>Translated_649_residues
MRHYGLELVKKAGVGIRLVGEEKQKQALAAELLHLSHREYTPEERQLMILIALLEAGEPVKLVSLANDLNVTVATVSLDL
DKLEQTLKAYGLSLIRKRGYGVELAGSESAKRRLISELLFRHVNEHEFLELMKETIQKRSDDPLDTVAEKLLGLVDRKKL
AIIEKQIEQVKEKLPFTMADSSYIAFVVHLALAIERIKRGEAIHFDPHDLRTLQAAKEFAIAEMLAESLERAFGINIPKE
EIGYMTMHLMGAKWRSRQGMMMEEPSLVVGMKAQQLIRFVSRELGVDLSTDRTLYEDLVVHLKPALYRLEHGMGVANPLL
DQIRKDYPELFAVVANGTKQLFGYIPVPEEEIGYLVLHFAAALMREKKGWRALVICSSGLGTAKILATRLKRAIPDITVM
EQASVFELKKKDLRAYDLVISTVPLPEEYGPHVIVSPMLTEEEARAIRQRLERKTAVEKRRENESIARRNRSMLATMKAV
RRISETIIHLLDGFLLEMVTCRSIHELLMNACRRLERNGVLVDAKVVIEELERRESLGGLGVPGTKLALYHARSFSVLRP
SLTMYRLDEPQTVAGMDGEPMEVNTVVLLLGPADADEEMLSVLSQVSTLLVKDEQSTATLARGGENEVYSLVSSHLEQFF
DHYWTTTKE
>Mature_649_residues
MRHYGLELVKKAGVGIRLVGEEKQKQALAAELLHLSHREYTPEERQLMILIALLEAGEPVKLVSLANDLNVTVATVSLDL
DKLEQTLKAYGLSLIRKRGYGVELAGSESAKRRLISELLFRHVNEHEFLELMKETIQKRSDDPLDTVAEKLLGLVDRKKL
AIIEKQIEQVKEKLPFTMADSSYIAFVVHLALAIERIKRGEAIHFDPHDLRTLQAAKEFAIAEMLAESLERAFGINIPKE
EIGYMTMHLMGAKWRSRQGMMMEEPSLVVGMKAQQLIRFVSRELGVDLSTDRTLYEDLVVHLKPALYRLEHGMGVANPLL
DQIRKDYPELFAVVANGTKQLFGYIPVPEEEIGYLVLHFAAALMREKKGWRALVICSSGLGTAKILATRLKRAIPDITVM
EQASVFELKKKDLRAYDLVISTVPLPEEYGPHVIVSPMLTEEEARAIRQRLERKTAVEKRRENESIARRNRSMLATMKAV
RRISETIIHLLDGFLLEMVTCRSIHELLMNACRRLERNGVLVDAKVVIEELERRESLGGLGVPGTKLALYHARSFSVLRP
SLTMYRLDEPQTVAGMDGEPMEVNTVVLLLGPADADEEMLSVLSQVSTLLVKDEQSTATLARGGENEVYSLVSSHLEQFF
DHYWTTTKE

Specific function: Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 73287; Mature: 73287

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHYGLELVKKAGVGIRLVGEEKQKQALAAELLHLSHREYTPEERQLMILIALLEAGEPV
CCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCE
KLVSLANDLNVTVATVSLDLDKLEQTLKAYGLSLIRKRGYGVELAGSESAKRRLISELLF
EEEEECCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHH
RHVNEHEFLELMKETIQKRSDDPLDTVAEKLLGLVDRKKLAIIEKQIEQVKEKLPFTMAD
HHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECC
SSYIAFVVHLALAIERIKRGEAIHFDPHDLRTLQAAKEFAIAEMLAESLERAFGINIPKE
CHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
EIGYMTMHLMGAKWRSRQGMMMEEPSLVVGMKAQQLIRFVSRELGVDLSTDRTLYEDLVV
HHHHHHHHHHCCHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
HLKPALYRLEHGMGVANPLLDQIRKDYPELFAVVANGTKQLFGYIPVPEEEIGYLVLHFA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHH
AALMREKKGWRALVICSSGLGTAKILATRLKRAIPDITVMEQASVFELKKKDLRAYDLVI
HHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHE
STVPLPEEYGPHVIVSPMLTEEEARAIRQRLERKTAVEKRRENESIARRNRSMLATMKAV
ECCCCCHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRISETIIHLLDGFLLEMVTCRSIHELLMNACRRLERNGVLVDAKVVIEELERRESLGGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCC
GVPGTKLALYHARSFSVLRPSLTMYRLDEPQTVAGMDGEPMEVNTVVLLLGPADADEEML
CCCCCCEEEEECCCHHHHCCCCEEEECCCCCEECCCCCCCEEEEEEEEEECCCCCCHHHH
SVLSQVSTLLVKDEQSTATLARGGENEVYSLVSSHLEQFFDHYWTTTKE
HHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRHYGLELVKKAGVGIRLVGEEKQKQALAAELLHLSHREYTPEERQLMILIALLEAGEPV
CCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCE
KLVSLANDLNVTVATVSLDLDKLEQTLKAYGLSLIRKRGYGVELAGSESAKRRLISELLF
EEEEECCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHH
RHVNEHEFLELMKETIQKRSDDPLDTVAEKLLGLVDRKKLAIIEKQIEQVKEKLPFTMAD
HHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECC
SSYIAFVVHLALAIERIKRGEAIHFDPHDLRTLQAAKEFAIAEMLAESLERAFGINIPKE
CHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
EIGYMTMHLMGAKWRSRQGMMMEEPSLVVGMKAQQLIRFVSRELGVDLSTDRTLYEDLVV
HHHHHHHHHHCCHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
HLKPALYRLEHGMGVANPLLDQIRKDYPELFAVVANGTKQLFGYIPVPEEEIGYLVLHFA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHH
AALMREKKGWRALVICSSGLGTAKILATRLKRAIPDITVMEQASVFELKKKDLRAYDLVI
HHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHE
STVPLPEEYGPHVIVSPMLTEEEARAIRQRLERKTAVEKRRENESIARRNRSMLATMKAV
ECCCCCHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRISETIIHLLDGFLLEMVTCRSIHELLMNACRRLERNGVLVDAKVVIEELERRESLGGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCC
GVPGTKLALYHARSFSVLRPSLTMYRLDEPQTVAGMDGEPMEVNTVVLLLGPADADEEML
CCCCCCEEEEECCCHHHHCCCCEEEECCCCCEECCCCCCCEEEEEEEEEECCCCCCHHHH
SVLSQVSTLLVKDEQSTATLARGGENEVYSLVSSHLEQFFDHYWTTTKE
HHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]