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The map label for this gene is gntK [H]

Identifier: 138895488

GI number: 138895488

Start: 1956130

End: 1957677

Strand: Reverse

Name: gntK [H]

Synonym: GTNG_1836

Alternate gene names: 138895488

Gene position: 1957677-1956130 (Counterclockwise)

Preceding gene: 138895489

Following gene: 138895487

Centisome position: 55.14

GC content: 55.17

Gene sequence:

>1548_bases
ATGGCGATTTCTGAGGATGTTGTCATTGGCATTGATATTGGAACGACAAGCACGAAAGCGGTTGTTTTCGGAGAACGTGG
GCGGGTATTAGCTTCCCACGCGGTTGATTATCCAATCATCCAGCCGCATCCGGGATTTGCGGAACAGGACCCGGAAGAGC
TGTTTGCCGCGGTCATTCAAGCGGTCGGGGCGGTGACGGTCCGCCATGGGATTCGTCCCCAGCAGGTGAAGGCGATTGGA
TTGAGTGCGGCGATGCACTCGATGATGGCGCTTGACGAATCAGGACGGCCGCTCACTCGCTTAATCATCTGGGCCGACAA
CCGGAGCGTCGTTCAGGCGGAGCGATTGTTGAAAGAGCATCATGGACTTGATATTTACCGGCGGACGGGGACGCCAATTC
ATCCGATGTCCCCATTGCCGAAATTGCTTTGGCTGAAAGAGGAGGAGCCGGATGTATTCCGACAGGCGCACCGTTTCGTG
TCGGTGAAAGATTATGTGCTGTATCGGCTGTACGGTGACTATGTCACCGACCATTCGCTCGCCTCAGCGACGGGCTTGTT
CCGCCTCGATACGCTCGATTGGGATGAGGATGTGCTTTCACTTCTTGGCATTGGCCGCGAACGCCTGCCTCGTTTGGTTC
CAGCCACGCACATTCTGCAAGGAATGAACAAAGAATGGGCCGATAAAATGGGGGTATCTCCTGATGTTCCAGTCGTCATC
GGTGCGAGCGATGGCGTGCTCGCCAACATCGGTGTCGGTGCCGTGCTCCCAGGTGAGGCGGCCATTACGATCGGGACGAG
CGGGGCGGTGCGGACGATTGCGACCACACCGACAACCGATGAAAAAGGCCGAACGTTTTGTTATGCGTTAACCCCTGGTT
ATTGGGTCGTTGGCGGGCCGACGAACAATGGCGGTATTTTGCTTCGGTGGCTGCGCGATGAGTTTGGCGCCCAAGAGCGA
GAAGTGGCGAAAAAGCTTGGCGTCGATCCATACGACTTGTTGACGAAGTATGCGGAACGCGTTTCACCCGGAGCGGAAGG
ATTGGTGTTTTTGCCATTTTTATCGGGCGAGCGGGCCCCATATTGGAACGCGAATGCACGCGGAACATTTTTTGGCCTTG
GCCTTCACCATAAGCGCGAACATTTCATTCGTGCCGTGATGGAAGGCGTCTGCTTCAGCATCGTATCGGTGGCGCTTGCC
ATTCGCGACGTGACAGGACCAATGGCGGAAATCCGCGTCTCAGGCGGTTTTGCAAAATCTCCATTTTGGCGGCAAATGCT
TTCCGATATGCTCGGTAAGCCGCTCATTGTGCCGCAAACGCACGAGGCATCGGCATTAGGAGCAGCGGCGGTGGCGCTTC
ATGCGTTAGGTGAAGTGCCGTCCTTAGAGATGGTGAAAACGTGGATTGATACGACGGCTCGCCATGAACCGAAGGAGGAA
CATACGCTTATTTACGCAGAGTTGTTTGATTTGTATGCCCGTTTGTATGAGCGGTTAAAAGCGGAGTTTGATATCATCGC
TGCGTTTCAGCGGCGGAGTGGAGAATAG

Upstream 100 bases:

>100_bases
CAGGAGCGAACGCGCAAACCGCGTGTGTTTCGTTTCTCCCCGACATTGGTGGAACGGACATCGATCAGATGAGAAAGCAG
ATAAGGAGGGAGGAGAAACG

Downstream 100 bases:

>100_bases
CATTTTTGAACTAAATCGGTTTATTAGCGGAAGAGAGTGAGTTTGCCAGCAACGCTTTCTCTTCCGCTCTCCTACTTGCA
GTTGAGGCGACTTTGATGAA

Product: gluconokinase

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MAISEDVVIGIDIGTTSTKAVVFGERGRVLASHAVDYPIIQPHPGFAEQDPEELFAAVIQAVGAVTVRHGIRPQQVKAIG
LSAAMHSMMALDESGRPLTRLIIWADNRSVVQAERLLKEHHGLDIYRRTGTPIHPMSPLPKLLWLKEEEPDVFRQAHRFV
SVKDYVLYRLYGDYVTDHSLASATGLFRLDTLDWDEDVLSLLGIGRERLPRLVPATHILQGMNKEWADKMGVSPDVPVVI
GASDGVLANIGVGAVLPGEAAITIGTSGAVRTIATTPTTDEKGRTFCYALTPGYWVVGGPTNNGGILLRWLRDEFGAQER
EVAKKLGVDPYDLLTKYAERVSPGAEGLVFLPFLSGERAPYWNANARGTFFGLGLHHKREHFIRAVMEGVCFSIVSVALA
IRDVTGPMAEIRVSGGFAKSPFWRQMLSDMLGKPLIVPQTHEASALGAAAVALHALGEVPSLEMVKTWIDTTARHEPKEE
HTLIYAELFDLYARLYERLKAEFDIIAAFQRRSGE

Sequences:

>Translated_515_residues
MAISEDVVIGIDIGTTSTKAVVFGERGRVLASHAVDYPIIQPHPGFAEQDPEELFAAVIQAVGAVTVRHGIRPQQVKAIG
LSAAMHSMMALDESGRPLTRLIIWADNRSVVQAERLLKEHHGLDIYRRTGTPIHPMSPLPKLLWLKEEEPDVFRQAHRFV
SVKDYVLYRLYGDYVTDHSLASATGLFRLDTLDWDEDVLSLLGIGRERLPRLVPATHILQGMNKEWADKMGVSPDVPVVI
GASDGVLANIGVGAVLPGEAAITIGTSGAVRTIATTPTTDEKGRTFCYALTPGYWVVGGPTNNGGILLRWLRDEFGAQER
EVAKKLGVDPYDLLTKYAERVSPGAEGLVFLPFLSGERAPYWNANARGTFFGLGLHHKREHFIRAVMEGVCFSIVSVALA
IRDVTGPMAEIRVSGGFAKSPFWRQMLSDMLGKPLIVPQTHEASALGAAAVALHALGEVPSLEMVKTWIDTTARHEPKEE
HTLIYAELFDLYARLYERLKAEFDIIAAFQRRSGE
>Mature_514_residues
AISEDVVIGIDIGTTSTKAVVFGERGRVLASHAVDYPIIQPHPGFAEQDPEELFAAVIQAVGAVTVRHGIRPQQVKAIGL
SAAMHSMMALDESGRPLTRLIIWADNRSVVQAERLLKEHHGLDIYRRTGTPIHPMSPLPKLLWLKEEEPDVFRQAHRFVS
VKDYVLYRLYGDYVTDHSLASATGLFRLDTLDWDEDVLSLLGIGRERLPRLVPATHILQGMNKEWADKMGVSPDVPVVIG
ASDGVLANIGVGAVLPGEAAITIGTSGAVRTIATTPTTDEKGRTFCYALTPGYWVVGGPTNNGGILLRWLRDEFGAQERE
VAKKLGVDPYDLLTKYAERVSPGAEGLVFLPFLSGERAPYWNANARGTFFGLGLHHKREHFIRAVMEGVCFSIVSVALAI
RDVTGPMAEIRVSGGFAKSPFWRQMLSDMLGKPLIVPQTHEASALGAAAVALHALGEVPSLEMVKTWIDTTARHEPKEEH
TLIYAELFDLYARLYERLKAEFDIIAAFQRRSGE

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=473, Percent_Identity=28.1183932346723, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI4504007, Length=473, Percent_Identity=28.1183932346723, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI189409120, Length=473, Percent_Identity=28.1183932346723, Blast_Score=159, Evalue=7e-39,
Organism=Homo sapiens, GI41393575, Length=460, Percent_Identity=27.3913043478261, Blast_Score=150, Evalue=4e-36,
Organism=Homo sapiens, GI88196792, Length=511, Percent_Identity=25.2446183953033, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI164663828, Length=558, Percent_Identity=25.2688172043011, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI164663830, Length=578, Percent_Identity=24.3944636678201, Blast_Score=109, Evalue=7e-24,
Organism=Escherichia coli, GI1789987, Length=496, Percent_Identity=31.0483870967742, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1787789, Length=513, Percent_Identity=27.4853801169591, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1790361, Length=485, Percent_Identity=29.2783505154639, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI1790005, Length=458, Percent_Identity=27.0742358078603, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789168, Length=494, Percent_Identity=23.2793522267206, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789138, Length=477, Percent_Identity=23.0607966457023, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790338, Length=458, Percent_Identity=21.3973799126638, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17535599, Length=518, Percent_Identity=27.027027027027, Blast_Score=161, Evalue=8e-40,
Organism=Saccharomyces cerevisiae, GI6321755, Length=510, Percent_Identity=25.6862745098039, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6320314, Length=520, Percent_Identity=23.8461538461538, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17864214, Length=475, Percent_Identity=27.1578947368421, Blast_Score=159, Evalue=6e-39,
Organism=Drosophila melanogaster, GI24655555, Length=448, Percent_Identity=26.5625, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24655560, Length=448, Percent_Identity=26.5625, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24655570, Length=448, Percent_Identity=26.5625, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24655574, Length=448, Percent_Identity=26.5625, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24655565, Length=448, Percent_Identity=26.5625, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24654573, Length=412, Percent_Identity=26.9417475728155, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24657106, Length=552, Percent_Identity=24.4565217391304, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24657102, Length=552, Percent_Identity=24.4565217391304, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21357867, Length=535, Percent_Identity=21.6822429906542, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24656367, Length=523, Percent_Identity=21.6061185468451, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24656372, Length=346, Percent_Identity=24.2774566473988, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356323, Length=446, Percent_Identity=23.3183856502242, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 56582; Mature: 56451

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISEDVVIGIDIGTTSTKAVVFGERGRVLASHAVDYPIIQPHPGFAEQDPEELFAAVIQ
CCCCCCEEEEEEECCCCCEEEEECCCCCEEEHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
AVGAVTVRHGIRPQQVKAIGLSAAMHSMMALDESGRPLTRLIIWADNRSVVQAERLLKEH
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHH
HGLDIYRRTGTPIHPMSPLPKLLWLKEEEPDVFRQAHRFVSVKDYVLYRLYGDYVTDHSL
CCCEEEECCCCCCCCCCCCCHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ASATGLFRLDTLDWDEDVLSLLGIGRERLPRLVPATHILQGMNKEWADKMGVSPDVPVVI
HHHCCEEEEECCCCHHHHHHHHCCCHHHHHHHCCHHHHHHCCCHHHHHHCCCCCCCCEEE
GASDGVLANIGVGAVLPGEAAITIGTSGAVRTIATTPTTDEKGRTFCYALTPGYWVVGGP
ECCCCEEEECCCCEECCCCEEEEEECCCCEEEEEECCCCCCCCCEEEEEECCCEEEECCC
TNNGGILLRWLRDEFGAQEREVAKKLGVDPYDLLTKYAERVSPGAEGLVFLPFLSGERAP
CCCCCEEEEEHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCC
YWNANARGTFFGLGLHHKREHFIRAVMEGVCFSIVSVALAIRDVTGPMAEIRVSGGFAKS
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
PFWRQMLSDMLGKPLIVPQTHEASALGAAAVALHALGEVPSLEMVKTWIDTTARHEPKEE
HHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHH
HTLIYAELFDLYARLYERLKAEFDIIAAFQRRSGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AISEDVVIGIDIGTTSTKAVVFGERGRVLASHAVDYPIIQPHPGFAEQDPEELFAAVIQ
CCCCCEEEEEEECCCCCEEEEECCCCCEEEHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
AVGAVTVRHGIRPQQVKAIGLSAAMHSMMALDESGRPLTRLIIWADNRSVVQAERLLKEH
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHH
HGLDIYRRTGTPIHPMSPLPKLLWLKEEEPDVFRQAHRFVSVKDYVLYRLYGDYVTDHSL
CCCEEEECCCCCCCCCCCCCHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ASATGLFRLDTLDWDEDVLSLLGIGRERLPRLVPATHILQGMNKEWADKMGVSPDVPVVI
HHHCCEEEEECCCCHHHHHHHHCCCHHHHHHHCCHHHHHHCCCHHHHHHCCCCCCCCEEE
GASDGVLANIGVGAVLPGEAAITIGTSGAVRTIATTPTTDEKGRTFCYALTPGYWVVGGP
ECCCCEEEECCCCEECCCCEEEEEECCCCEEEEEECCCCCCCCCEEEEEECCCEEEECCC
TNNGGILLRWLRDEFGAQEREVAKKLGVDPYDLLTKYAERVSPGAEGLVFLPFLSGERAP
CCCCCEEEEEHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCC
YWNANARGTFFGLGLHHKREHFIRAVMEGVCFSIVSVALAIRDVTGPMAEIRVSGGFAKS
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
PFWRQMLSDMLGKPLIVPQTHEASALGAAAVALHALGEVPSLEMVKTWIDTTARHEPKEE
HHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHH
HTLIYAELFDLYARLYERLKAEFDIIAAFQRRSGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8535972 [H]