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The map label for this gene is gntU [H]

Identifier: 138895487

GI number: 138895487

Start: 1954672

End: 1956015

Strand: Reverse

Name: gntU [H]

Synonym: GTNG_1835

Alternate gene names: 138895487

Gene position: 1956015-1954672 (Counterclockwise)

Preceding gene: 138895488

Following gene: 138895485

Centisome position: 55.09

GC content: 46.35

Gene sequence:

>1344_bases
ATGTCTGACTCAGCCTTGATCCTTATCGTCATTGCCGGGATTAGTTTACTATTGTTTTTGATTATTCGCTCAAAGCTTCA
TGCGTTTGTTGCCTTGTTGCTTGTTAGTTTGCTTGTCGGTGCAGCTGCTGGCATGCCGCTAGACAAAGTCATCGAGTCAA
TTCAAAATGGAATGGGTGGTACACTTGGCTTTGTGGCAGTGGTTGTTGGGTTAGGCGCTATGTTTGGGCAAATGCTAGAA
GTATCTGGGGGAGCCGAACGGCTGGCTCAGACGCTCATCAATAAGTTTGGAGAGAATAAAGCACAATGGGCGCTCGGTCT
GACAGGGTTTATTGTTGCGATTCCGGTCTTTTTTGATGTTGGTTTCATTATTCTTGTTCCCATTGTCTATGGCTTGGCGC
GGAAAACAGGGCGTTCACTTTTGTATTATGGCATCCCGCTTCTAGCTGGGTTAGCTGTCACGCATAGTTTTGTGCCACCA
ACGCCAGGTCCGATTGCTGTTGCAGATTTGATTGGTGCTGATCTTGGATGGGTCATTTTATTCGGTTTTATCGCCGGTCT
TCCAGCGATGATTGTAGCTGGCCCACTGTTTGGAAAATATATTGCCAAAAAAATTCACGCTACCGTTCCAGATTATATGG
ATATGAAAGAAAAGCAATGGGAGAAAGACCTCCCGGGGTTTGGGACGATTGCCGGCATCATTTTTATTCCGCTCGTGTTG
ATTTTGTTGAATACGGTTTCAGGAGCTGTTTTGCCAGAGGGGAACGGGATAAGGACGTTCTTAACCTTTTTAGGCCATCC
GTTTGTCGCGCTGACGATTGCGACATTGTTGGCGTTTTACTTGCTTGGGCAAAAAAGAGGGTTCACTAAGCAAGAAGTAC
AAGATATTGCCACAAAATCATTGGAACCGGCTGGCATTATTATTCTTGTCACCGGAGCCGGGGGTGTGTTCAAACAAATT
TTGATCGATTCCGGCGTCGGAAAAGTGTTAGCTGACATGATGGCAACTTCTTCCTTGCCACCGATCGTACTGGCGTTTCT
TATCGCTGCGATCGTCCGTGTGTCCCAAGGTTCGGCAACTGTGGCCATGGTAACAGCTGCTGGCCTGATAGCACCGTTAA
TTGAAACACTAGGATTAAGTGGTCCGATTTTAGGAATGATTGTTATTGCCATCGCTGCCGGGGCAACGATCCTTTCACAC
GTCAACGACTCTGGTTTTTGGCTCGTCAACCGTTATTTCGGTCTCGATGTGAAAGATACACTGAAATCGTGGACGGTCAT
GGAGACGTTGATTGCACTTGTCGGTTTTGTCGTTGTATTGATTTTGAGTTTGTTTGTGTCATAA

Upstream 100 bases:

>100_bases
ATCGGTTTATTAGCGGAAGAGAGTGAGTTTGCCAGCAACGCTTTCTCTTCCGCTCTCCTACTTGCAGTTGAGGCGACTTT
GATGAACAGGAGGAAGAAAA

Downstream 100 bases:

>100_bases
AAACGAGTAAGAAGAAAGAAGAGGATTTGGATAGAGGGTGTCTCAAAAGCAACGAGACACCCTTTCTTACTATGATATAC
ACACTGGGCGACTTTGCAGT

Product: gluconate transporter

Products: Proton [Cytoplasm]; gluconate [Cytoplasm] [C]

Alternate protein names: Gluconate permease; Gnt-I system [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MSDSALILIVIAGISLLLFLIIRSKLHAFVALLLVSLLVGAAAGMPLDKVIESIQNGMGGTLGFVAVVVGLGAMFGQMLE
VSGGAERLAQTLINKFGENKAQWALGLTGFIVAIPVFFDVGFIILVPIVYGLARKTGRSLLYYGIPLLAGLAVTHSFVPP
TPGPIAVADLIGADLGWVILFGFIAGLPAMIVAGPLFGKYIAKKIHATVPDYMDMKEKQWEKDLPGFGTIAGIIFIPLVL
ILLNTVSGAVLPEGNGIRTFLTFLGHPFVALTIATLLAFYLLGQKRGFTKQEVQDIATKSLEPAGIIILVTGAGGVFKQI
LIDSGVGKVLADMMATSSLPPIVLAFLIAAIVRVSQGSATVAMVTAAGLIAPLIETLGLSGPILGMIVIAIAAGATILSH
VNDSGFWLVNRYFGLDVKDTLKSWTVMETLIALVGFVVVLILSLFVS

Sequences:

>Translated_447_residues
MSDSALILIVIAGISLLLFLIIRSKLHAFVALLLVSLLVGAAAGMPLDKVIESIQNGMGGTLGFVAVVVGLGAMFGQMLE
VSGGAERLAQTLINKFGENKAQWALGLTGFIVAIPVFFDVGFIILVPIVYGLARKTGRSLLYYGIPLLAGLAVTHSFVPP
TPGPIAVADLIGADLGWVILFGFIAGLPAMIVAGPLFGKYIAKKIHATVPDYMDMKEKQWEKDLPGFGTIAGIIFIPLVL
ILLNTVSGAVLPEGNGIRTFLTFLGHPFVALTIATLLAFYLLGQKRGFTKQEVQDIATKSLEPAGIIILVTGAGGVFKQI
LIDSGVGKVLADMMATSSLPPIVLAFLIAAIVRVSQGSATVAMVTAAGLIAPLIETLGLSGPILGMIVIAIAAGATILSH
VNDSGFWLVNRYFGLDVKDTLKSWTVMETLIALVGFVVVLILSLFVS
>Mature_446_residues
SDSALILIVIAGISLLLFLIIRSKLHAFVALLLVSLLVGAAAGMPLDKVIESIQNGMGGTLGFVAVVVGLGAMFGQMLEV
SGGAERLAQTLINKFGENKAQWALGLTGFIVAIPVFFDVGFIILVPIVYGLARKTGRSLLYYGIPLLAGLAVTHSFVPPT
PGPIAVADLIGADLGWVILFGFIAGLPAMIVAGPLFGKYIAKKIHATVPDYMDMKEKQWEKDLPGFGTIAGIIFIPLVLI
LLNTVSGAVLPEGNGIRTFLTFLGHPFVALTIATLLAFYLLGQKRGFTKQEVQDIATKSLEPAGIIILVTGAGGVFKQIL
IDSGVGKVLADMMATSSLPPIVLAFLIAAIVRVSQGSATVAMVTAAGLIAPLIETLGLSGPILGMIVIAIAAGATILSHV
NDSGFWLVNRYFGLDVKDTLKSWTVMETLIALVGFVVVLILSLFVS

Specific function: Part of the gluconate utilization system Gnt-I; low- affinity intake of gluconate [H]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994939, Length=442, Percent_Identity=44.1176470588235, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI48994935, Length=440, Percent_Identity=43.1818181818182, Blast_Score=361, Evalue=1e-101,
Organism=Escherichia coli, GI1790716, Length=437, Percent_Identity=42.3340961098398, Blast_Score=354, Evalue=5e-99,
Organism=Escherichia coli, GI1789097, Length=449, Percent_Identity=42.7616926503341, Blast_Score=310, Evalue=9e-86,
Organism=Escherichia coli, GI2367370, Length=451, Percent_Identity=39.4678492239468, Blast_Score=301, Evalue=5e-83,
Organism=Escherichia coli, GI1790776, Length=441, Percent_Identity=34.6938775510204, Blast_Score=265, Evalue=4e-72,
Organism=Escherichia coli, GI1788707, Length=441, Percent_Identity=36.5079365079365, Blast_Score=261, Evalue=5e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 46832; Mature: 46701

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDSALILIVIAGISLLLFLIIRSKLHAFVALLLVSLLVGAAAGMPLDKVIESIQNGMGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCH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HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]