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The map label for this gene is mmgC [H]

Identifier: 138895165

GI number: 138895165

Start: 1587818

End: 1589077

Strand: Direct

Name: mmgC [H]

Synonym: GTNG_1503

Alternate gene names: 138895165

Gene position: 1587818-1589077 (Clockwise)

Preceding gene: 138895164

Following gene: 138895166

Centisome position: 44.72

GC content: 51.51

Gene sequence:

>1260_bases
ATGAAGGTAACATACCAACCGGTTGGTATTTATGGGAGTGGGAAGTCGCTTCAAAGTGTAATGAAAACGGGGGGAACCAT
TATGTACTTGCGCTTAACGGATGAGCAACGCATGGTCCAAAAGGCCATTCGCAAGTTTGTTGAAAAAGAGTTGATGCCGC
TAGAAAATGAAGTATTGCGCAACGAGCGGGAAGGGAAGCCCGGGCTTACGCCGGAGAAATTAAAAGAGCTGCAATTAAAG
GCGAAAGAGGCGGGTTTTTGGGGGATTAATACGCCAGAGGAGTACGGTGGCGCGAATCTTGGCCATGTCATGCAGGCGAT
TGTGCTCATGGAAGTGGCAAAAACGCTCGTTCCCTTCCAGTTTGGCGGGTCGGCGGATAACATTTTGTATTACGCCAACG
AAGAACAAAAGAAAAAATATTTAATCCCAACGATCAACGGTGAGAAAAAATCGTGCTTTGCCATGACCGAGCCGGGGGCA
GGGTCTGATACGCGCAACATTAAAATGACAGCGGTCAAAGACGGGGACGAATGGGTGCTCAACGGGGAAAAAACGTTCAT
CACTGGGGGCAATGACGCCGATTTCGTTATGGTCATTGCCATTACCGACAAAGAGCGGCATCAAGCGACAAACGGCCGTG
AAGGGGTGACGTGCTTTATCGTCGACCGCGACATGGGCTGGCGCTCCGAGCCGATACATACAATGGGGCCGTCAACACCG
GCTAGCTTAATTTTTGAAAACGTGCGCGTGCCGGAAGAAAACATTTTAGGTGAGCTGCACTACGGCTACAAGCTCGGTCT
TGAGTGGATCGGCTATGCGCGATGGGTCGTCGGCGCACGCGCGGTCGGAACGGCCGAGCGGCTGTTGCAAATGGCGATCG
ATTATGCGAAAGAGCGTGTCACATTCGGCAAGCCGATCGCCGAACGGCAAGCGATCCAATGGATGATCGCCGATTCAGCA
GTGGAAATTGAAGCAGCGAAATGGCTCGTCTTAAACGCAGCGTTTACGCTTGATGAAGGGGAGGACAACCGTCATTTGGC
TTCGATGGCGAAACTGTTTGGTGCGAACATGGGCAACCGTGTGGTTGACCGGGTGATGCAAATTCACGGGGGCATGGGCT
ATACGAAAGAGATGCCGATTGAGCGTTGGTACCGCGAGGCGAGATTGTGGCGCATTTACGATGGCACCGATGAAATTCAA
CGTCTTATTATTGCCCGCAACTTAATTAAAGGACACGTCAAGCTTGGGCAGTTTCTCTAA

Upstream 100 bases:

>100_bases
TTGATTCGCAGCACTGGCACCAACAGGAGAACGTACTCAACGTTTTCCTGTTGGACAAAAGCATAAAAAAGTATTGTACT
TTTCAGAACATTCGAATATA

Downstream 100 bases:

>100_bases
CAAAATGAAAGCGTTACTAAAAGGGGAGGAGAAAAACATGAGTCAACGGTTTGCAGGAAGAGTGGCGTTTGTGACAGGAG
GAAGCCGCGGCATCGGAAAG

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MKVTYQPVGIYGSGKSLQSVMKTGGTIMYLRLTDEQRMVQKAIRKFVEKELMPLENEVLRNEREGKPGLTPEKLKELQLK
AKEAGFWGINTPEEYGGANLGHVMQAIVLMEVAKTLVPFQFGGSADNILYYANEEQKKKYLIPTINGEKKSCFAMTEPGA
GSDTRNIKMTAVKDGDEWVLNGEKTFITGGNDADFVMVIAITDKERHQATNGREGVTCFIVDRDMGWRSEPIHTMGPSTP
ASLIFENVRVPEENILGELHYGYKLGLEWIGYARWVVGARAVGTAERLLQMAIDYAKERVTFGKPIAERQAIQWMIADSA
VEIEAAKWLVLNAAFTLDEGEDNRHLASMAKLFGANMGNRVVDRVMQIHGGMGYTKEMPIERWYREARLWRIYDGTDEIQ
RLIIARNLIKGHVKLGQFL

Sequences:

>Translated_419_residues
MKVTYQPVGIYGSGKSLQSVMKTGGTIMYLRLTDEQRMVQKAIRKFVEKELMPLENEVLRNEREGKPGLTPEKLKELQLK
AKEAGFWGINTPEEYGGANLGHVMQAIVLMEVAKTLVPFQFGGSADNILYYANEEQKKKYLIPTINGEKKSCFAMTEPGA
GSDTRNIKMTAVKDGDEWVLNGEKTFITGGNDADFVMVIAITDKERHQATNGREGVTCFIVDRDMGWRSEPIHTMGPSTP
ASLIFENVRVPEENILGELHYGYKLGLEWIGYARWVVGARAVGTAERLLQMAIDYAKERVTFGKPIAERQAIQWMIADSA
VEIEAAKWLVLNAAFTLDEGEDNRHLASMAKLFGANMGNRVVDRVMQIHGGMGYTKEMPIERWYREARLWRIYDGTDEIQ
RLIIARNLIKGHVKLGQFL
>Mature_419_residues
MKVTYQPVGIYGSGKSLQSVMKTGGTIMYLRLTDEQRMVQKAIRKFVEKELMPLENEVLRNEREGKPGLTPEKLKELQLK
AKEAGFWGINTPEEYGGANLGHVMQAIVLMEVAKTLVPFQFGGSADNILYYANEEQKKKYLIPTINGEKKSCFAMTEPGA
GSDTRNIKMTAVKDGDEWVLNGEKTFITGGNDADFVMVIAITDKERHQATNGREGVTCFIVDRDMGWRSEPIHTMGPSTP
ASLIFENVRVPEENILGELHYGYKLGLEWIGYARWVVGARAVGTAERLLQMAIDYAKERVTFGKPIAERQAIQWMIADSA
VEIEAAKWLVLNAAFTLDEGEDNRHLASMAKLFGANMGNRVVDRVMQIHGGMGYTKEMPIERWYREARLWRIYDGTDEIQ
RLIIARNLIKGHVKLGQFL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=394, Percent_Identity=34.7715736040609, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI4557231, Length=389, Percent_Identity=34.9614395886889, Blast_Score=214, Evalue=9e-56,
Organism=Homo sapiens, GI187960098, Length=389, Percent_Identity=35.2185089974293, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI4501859, Length=390, Percent_Identity=33.5897435897436, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI226958412, Length=385, Percent_Identity=32.2077922077922, Blast_Score=195, Evalue=8e-50,
Organism=Homo sapiens, GI7656849, Length=397, Percent_Identity=28.463476070529, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI4501857, Length=387, Percent_Identity=32.0413436692506, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI226958414, Length=367, Percent_Identity=32.1525885558583, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI21361497, Length=362, Percent_Identity=34.5303867403315, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI76496475, Length=392, Percent_Identity=32.3979591836735, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI4557235, Length=338, Percent_Identity=33.7278106508876, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI211971008, Length=405, Percent_Identity=30.3703703703704, Blast_Score=165, Evalue=8e-41,
Organism=Homo sapiens, GI48976061, Length=405, Percent_Identity=30.1234567901235, Blast_Score=165, Evalue=8e-41,
Organism=Homo sapiens, GI38505218, Length=439, Percent_Identity=28.4738041002278, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI4503943, Length=395, Percent_Identity=27.8481012658228, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI7669494, Length=369, Percent_Identity=27.9132791327913, Blast_Score=102, Evalue=7e-22,
Organism=Escherichia coli, GI87081958, Length=392, Percent_Identity=30.6122448979592, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1786223, Length=393, Percent_Identity=30.5343511450382, Blast_Score=151, Evalue=9e-38,
Organism=Escherichia coli, GI87081702, Length=369, Percent_Identity=23.5772357723577, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17534899, Length=398, Percent_Identity=36.6834170854271, Blast_Score=227, Evalue=8e-60,
Organism=Caenorhabditis elegans, GI17569725, Length=410, Percent_Identity=34.1463414634146, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17508101, Length=387, Percent_Identity=34.1085271317829, Blast_Score=208, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI17570075, Length=404, Percent_Identity=32.1782178217822, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17538396, Length=389, Percent_Identity=31.8766066838046, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17506239, Length=385, Percent_Identity=33.2467532467532, Blast_Score=196, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17533517, Length=393, Percent_Identity=28.498727735369, Blast_Score=167, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI71985184, Length=398, Percent_Identity=28.391959798995, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17551932, Length=394, Percent_Identity=27.6649746192893, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71990804, Length=310, Percent_Identity=34.5161290322581, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI17505929, Length=383, Percent_Identity=28.9817232375979, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17562446, Length=389, Percent_Identity=30.0771208226221, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71982178, Length=287, Percent_Identity=32.7526132404181, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32563615, Length=235, Percent_Identity=33.1914893617021, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17531909, Length=245, Percent_Identity=33.469387755102, Blast_Score=117, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17534353, Length=388, Percent_Identity=26.2886597938144, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71985192, Length=332, Percent_Identity=27.1084337349398, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17531913, Length=172, Percent_Identity=31.9767441860465, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21356377, Length=392, Percent_Identity=36.4795918367347, Blast_Score=241, Evalue=7e-64,
Organism=Drosophila melanogaster, GI24660351, Length=386, Percent_Identity=36.0103626943005, Blast_Score=219, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24646207, Length=390, Percent_Identity=32.8205128205128, Blast_Score=208, Evalue=6e-54,
Organism=Drosophila melanogaster, GI24666513, Length=391, Percent_Identity=32.9923273657289, Blast_Score=197, Evalue=8e-51,
Organism=Drosophila melanogaster, GI281363737, Length=390, Percent_Identity=32.8205128205128, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI21355753, Length=389, Percent_Identity=31.6195372750643, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI19920834, Length=398, Percent_Identity=27.6381909547739, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 47202; Mature: 47202

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTYQPVGIYGSGKSLQSVMKTGGTIMYLRLTDEQRMVQKAIRKFVEKELMPLENEVLR
CEEEEEEEEEEECCHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHH
NEREGKPGLTPEKLKELQLKAKEAGFWGINTPEEYGGANLGHVMQAIVLMEVAKTLVPFQ
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCEE
FGGSADNILYYANEEQKKKYLIPTINGEKKSCFAMTEPGAGSDTRNIKMTAVKDGDEWVL
ECCCCCCEEEEECCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCEEEE
NGEKTFITGGNDADFVMVIAITDKERHQATNGREGVTCFIVDRDMGWRSEPIHTMGPSTP
CCCEEEEECCCCCCEEEEEEEECCHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCH
ASLIFENVRVPEENILGELHYGYKLGLEWIGYARWVVGARAVGTAERLLQMAIDYAKERV
HHHHHHHCCCCHHHHHEEECCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFGKPIAERQAIQWMIADSAVEIEAAKWLVLNAAFTLDEGEDNRHLASMAKLFGANMGNR
HCCCCHHHHHHHEEEEECCCEEEEEEEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCCHH
VVDRVMQIHGGMGYTKEMPIERWYREARLWRIYDGTDEIQRLIIARNLIKGHVKLGQFL
HHHHHHHHHCCCCCCCCCCHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVTYQPVGIYGSGKSLQSVMKTGGTIMYLRLTDEQRMVQKAIRKFVEKELMPLENEVLR
CEEEEEEEEEEECCHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHH
NEREGKPGLTPEKLKELQLKAKEAGFWGINTPEEYGGANLGHVMQAIVLMEVAKTLVPFQ
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCEE
FGGSADNILYYANEEQKKKYLIPTINGEKKSCFAMTEPGAGSDTRNIKMTAVKDGDEWVL
ECCCCCCEEEEECCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCEEEE
NGEKTFITGGNDADFVMVIAITDKERHQATNGREGVTCFIVDRDMGWRSEPIHTMGPSTP
CCCEEEEECCCCCCEEEEEEEECCHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCH
ASLIFENVRVPEENILGELHYGYKLGLEWIGYARWVVGARAVGTAERLLQMAIDYAKERV
HHHHHHHCCCCHHHHHEEECCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFGKPIAERQAIQWMIADSAVEIEAAKWLVLNAAFTLDEGEDNRHLASMAKLFGANMGNR
HCCCCHHHHHHHEEEEECCCEEEEEEEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCCHH
VVDRVMQIHGGMGYTKEMPIERWYREARLWRIYDGTDEIQRLIIARNLIKGHVKLGQFL
HHHHHHHHHCCCCCCCCCCHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]