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The map label for this gene is ymxG [H]

Identifier: 138894791

GI number: 138894791

Start: 1188189

End: 1189436

Strand: Direct

Name: ymxG [H]

Synonym: GTNG_1125

Alternate gene names: 138894791

Gene position: 1188189-1189436 (Clockwise)

Preceding gene: 138894790

Following gene: 138894793

Centisome position: 33.47

GC content: 50.88

Gene sequence:

>1248_bases
ATGGAGTTGATTAACAAATATACGTGCAAAAACGGTGTACGAATCGTGCTGGAGCAAATTCCGACCGTGCGCTCGGTGGC
CATTGGCGTATGGATCGGTACAGGCTCGCGCAACGAGACGGAACAAAACAACGGCATTTCCCATTTTTTGGAACACATGT
TTTTTAAAGGGACAACTACACGCACGGCTCGGGATATTGCGGAAGCGTTCGACAGCATCGGCGGACAAGTGAACGCCTTT
ACATCTAAGGAGTATACGTGCTATTACGCGAAAGTGTTGGATGAACACGCACCGCTGGCGCTGGAAATGCTCGCCGATAT
GTTTTTCCATTCAACGTTTGTTGAGGATGAGCTACAAAAAGAGCGCAACGTCGTGCTTGAAGAAATCAAAATGTATGAAG
ATACGCCAGATGACATCGTCCATGACTTGCTCGGCAAGGCATGCTATGCGAACCATCCGCTAGGCTACCCGATTTTAGGC
ACGGAAGAGACGTTGCGCACGTTTACTGGCGACACGCTGCGTCAATATATGGCTGACTATTATACACCGGACCGCGTCGT
TGTTTCGGTTGCTGGCAATGTCGATGAGCGGTTTATTGGGGAGATTGAACGCTATTTCGGTTCGTTTACGGCCGCCAATA
AGCCGGCCTCCCCCGGAAAGCCGTCGTTCGTACCGCAAAAACTTGCGCGCAAAAAAGACACCGAGCAAGCGCACGTATGC
ATCGGATTTAACGGGTTGCCGATCGGTCACCCGGACGCGTACCCGCTCCTTATTTTAAACAATATTTTAGGCGGCAGCAT
GAGCAGCCGGCTGTTCCAGGAGGTGCGCGAACAGCGCGGATTGGCCTATTCGGTCTTCTCGTACCATTCCGCCTACCAAG
ATAGCGGTTTGCTCGCTATTTATGCCGGTACGGGAAGCGGTCAGCTCGACATTTTGTTTGAAACGATCCAACGGACGCTT
TGCCATTTGAAAGAAGACGGCATTACGGAAAAAGAGCTGCATAACAGCAAAGAGCAAATGAAAGGAAGTTTAATGCTCGG
ACTTGAAAGCACAAATAGCCGCATGAGCCGCAATGGCAAAAACGAGCTTCTTCTCGGCCGCCATCGGTCGCTTGATGAAA
TTATCGAAGAGATCGAAAGTGTCACCGTCGAAAAAGTGAACGAGTTGGCGCGCACAGTTTTCGCGGAAGATTATGCCCTT
GCTCTCATCAGTCCCGACGGCGTTTTGCCGCAGCCGCTTCGTTCCTAG

Upstream 100 bases:

>100_bases
CTTGATGAGCTGATCGTTTCGATTCAGCGCCAAGGGTACGCCATCGGCAGCTTGACGGCCTTATTCGACGAGAAAAGACT
GGCAAAAAAACAGGAGGAAC

Downstream 100 bases:

>100_bases
CGAACATCGGCGCATAAAAAAAAGCTAACGACCTTCGTGAGGTTGTTAGCTTTTTCACTTTGTACGGCCGAGCCCCCCTA
TCATCCCTCTTCAGGTACGT

Product: processing peptidase-like protein

Products: NA

Alternate protein names: ORFP [H]

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MELINKYTCKNGVRIVLEQIPTVRSVAIGVWIGTGSRNETEQNNGISHFLEHMFFKGTTTRTARDIAEAFDSIGGQVNAF
TSKEYTCYYAKVLDEHAPLALEMLADMFFHSTFVEDELQKERNVVLEEIKMYEDTPDDIVHDLLGKACYANHPLGYPILG
TEETLRTFTGDTLRQYMADYYTPDRVVVSVAGNVDERFIGEIERYFGSFTAANKPASPGKPSFVPQKLARKKDTEQAHVC
IGFNGLPIGHPDAYPLLILNNILGGSMSSRLFQEVREQRGLAYSVFSYHSAYQDSGLLAIYAGTGSGQLDILFETIQRTL
CHLKEDGITEKELHNSKEQMKGSLMLGLESTNSRMSRNGKNELLLGRHRSLDEIIEEIESVTVEKVNELARTVFAEDYAL
ALISPDGVLPQPLRS

Sequences:

>Translated_415_residues
MELINKYTCKNGVRIVLEQIPTVRSVAIGVWIGTGSRNETEQNNGISHFLEHMFFKGTTTRTARDIAEAFDSIGGQVNAF
TSKEYTCYYAKVLDEHAPLALEMLADMFFHSTFVEDELQKERNVVLEEIKMYEDTPDDIVHDLLGKACYANHPLGYPILG
TEETLRTFTGDTLRQYMADYYTPDRVVVSVAGNVDERFIGEIERYFGSFTAANKPASPGKPSFVPQKLARKKDTEQAHVC
IGFNGLPIGHPDAYPLLILNNILGGSMSSRLFQEVREQRGLAYSVFSYHSAYQDSGLLAIYAGTGSGQLDILFETIQRTL
CHLKEDGITEKELHNSKEQMKGSLMLGLESTNSRMSRNGKNELLLGRHRSLDEIIEEIESVTVEKVNELARTVFAEDYAL
ALISPDGVLPQPLRS
>Mature_415_residues
MELINKYTCKNGVRIVLEQIPTVRSVAIGVWIGTGSRNETEQNNGISHFLEHMFFKGTTTRTARDIAEAFDSIGGQVNAF
TSKEYTCYYAKVLDEHAPLALEMLADMFFHSTFVEDELQKERNVVLEEIKMYEDTPDDIVHDLLGKACYANHPLGYPILG
TEETLRTFTGDTLRQYMADYYTPDRVVVSVAGNVDERFIGEIERYFGSFTAANKPASPGKPSFVPQKLARKKDTEQAHVC
IGFNGLPIGHPDAYPLLILNNILGGSMSSRLFQEVREQRGLAYSVFSYHSAYQDSGLLAIYAGTGSGQLDILFETIQRTL
CHLKEDGITEKELHNSKEQMKGSLMLGLESTNSRMSRNGKNELLLGRHRSLDEIIEEIESVTVEKVNELARTVFAEDYAL
ALISPDGVLPQPLRS

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=420, Percent_Identity=29.5238095238095, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI46593007, Length=417, Percent_Identity=27.5779376498801, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI24308013, Length=456, Percent_Identity=25.6578947368421, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI50592988, Length=382, Percent_Identity=17.8010471204188, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1787770, Length=187, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71999683, Length=408, Percent_Identity=28.1862745098039, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17553678, Length=426, Percent_Identity=26.9953051643192, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17510601, Length=419, Percent_Identity=21.2410501193317, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323192, Length=394, Percent_Identity=30.2030456852792, Blast_Score=207, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6321813, Length=405, Percent_Identity=26.9135802469136, Blast_Score=159, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6319426, Length=414, Percent_Identity=23.6714975845411, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21357875, Length=414, Percent_Identity=30.6763285024155, Blast_Score=198, Evalue=7e-51,
Organism=Drosophila melanogaster, GI24646943, Length=414, Percent_Identity=30.6763285024155, Blast_Score=198, Evalue=7e-51,
Organism=Drosophila melanogaster, GI19921772, Length=428, Percent_Identity=25.2336448598131, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24667786, Length=178, Percent_Identity=28.0898876404494, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24665395, Length=403, Percent_Identity=22.8287841191067, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 46454; Mature: 46454

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELINKYTCKNGVRIVLEQIPTVRSVAIGVWIGTGSRNETEQNNGISHFLEHMFFKGTTT
CCCCHHHHHCCCHHHHHHHCCCHHHEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCH
RTARDIAEAFDSIGGQVNAFTSKEYTCYYAKVLDEHAPLALEMLADMFFHSTFVEDELQK
HHHHHHHHHHHHCCCCEEEECCCCCEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ERNVVLEEIKMYEDTPDDIVHDLLGKACYANHPLGYPILGTEETLRTFTGDTLRQYMADY
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHH
YTPDRVVVSVAGNVDERFIGEIERYFGSFTAANKPASPGKPSFVPQKLARKKDTEQAHVC
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCEEEE
IGFNGLPIGHPDAYPLLILNNILGGSMSSRLFQEVREQRGLAYSVFSYHSAYQDSGLLAI
EECCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCEEEE
YAGTGSGQLDILFETIQRTLCHLKEDGITEKELHNSKEQMKGSLMLGLESTNSRMSRNGK
EECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHCCCEEEEECCCCHHHHCCCC
NELLLGRHRSLDEIIEEIESVTVEKVNELARTVFAEDYALALISPDGVLPQPLRS
CCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MELINKYTCKNGVRIVLEQIPTVRSVAIGVWIGTGSRNETEQNNGISHFLEHMFFKGTTT
CCCCHHHHHCCCHHHHHHHCCCHHHEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCH
RTARDIAEAFDSIGGQVNAFTSKEYTCYYAKVLDEHAPLALEMLADMFFHSTFVEDELQK
HHHHHHHHHHHHCCCCEEEECCCCCEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ERNVVLEEIKMYEDTPDDIVHDLLGKACYANHPLGYPILGTEETLRTFTGDTLRQYMADY
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHH
YTPDRVVVSVAGNVDERFIGEIERYFGSFTAANKPASPGKPSFVPQKLARKKDTEQAHVC
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCEEEE
IGFNGLPIGHPDAYPLLILNNILGGSMSSRLFQEVREQRGLAYSVFSYHSAYQDSGLLAI
EECCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCEEEE
YAGTGSGQLDILFETIQRTLCHLKEDGITEKELHNSKEQMKGSLMLGLESTNSRMSRNGK
EECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHCCCEEEEECCCCHHHHCCCC
NELLLGRHRSLDEIIEEIESVTVEKVNELARTVFAEDYALALISPDGVLPQPLRS
CCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 8098035 [H]