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The map label for this gene is rasP [H]

Identifier: 138894776

GI number: 138894776

Start: 1169741

End: 1170994

Strand: Direct

Name: rasP [H]

Synonym: GTNG_1110

Alternate gene names: 138894776

Gene position: 1169741-1170994 (Clockwise)

Preceding gene: 138894775

Following gene: 138894777

Centisome position: 32.95

GC content: 51.12

Gene sequence:

>1254_bases
TTGGAAACGATCATTTCGTTTATTGTCGTCTTTGGCGCCCTCGTCTTTTTTCACGAACTCGGTCACTTGCTGTTAGCGAA
GCGGGCCGGCATTCTTTGCCGCGAATTTGCCATCGGTTTCGGACCGAAAATGTTTTCGTTTAAGAAAAACGAAACGGTAT
ATACGGTCCGGCTTCTCCCGCTTGGCGGCTTCGTACGCATGGCGGGTGAAGACCCGGAAATGATTGAACTGAAGCGCGGG
CAAGTCGTCGGCCTGTTGCTTGATGACGAAGGGCAAGTAGAAAAAATCGTCATCAATCATAAGGACGATTACCCGAACAT
CCGGGTAATCGAGGTGGAAGACGCCGATTTGGAGCATGGCATGTATGTGACGGGCTATACTGACGGGGAGCGGCTTGAGC
GATTTGCTGTCAAAGAGCCGGCGTTTTTTGTCGCCGATCGCCAAGAAATTCAGATTGCTCCATACCACCGTCAGTTTGCT
GCGAAAACGCTCGGACAACGGACGATGGCGATTTTGGCTGGACCGCTCGCCAATTTTGTCTTGGCCCTTGTCGTCTTTAT
TTTGATCGGTCTCTTGCAAGGATACCCGGTCGACAAGCCGATCATCGGCGAGCTGACGCCGGAAGGGGCGGCGCGTGCGG
CTGGCTTGAAGCAAGGGGACGAAGTGATCGCGATCAACGGCGAACGTATGGAAACATGGACAGAAATTGTCAATACGATT
CGCGCTCATCCGAACGAACCGCTCCAATTTCAAATTGAACGGGGCGGAAACGAAATGAATGTGACCGTCACCCCAGAAGA
GAAAACGATTCAGGGGGAGACGATCGGCTTAATCGGCGTCTATCAGCCCATGGAAAAATCGGTGTTCGGTTCAGTGAAAC
AAGGGCTTATGGAGACGTACTATTGGACACGGCAAATTTTAGTCGGGCTCGGTCAATTGATCACCGGCCAGTTCCAACTT
GACATGTTGTCCGGTCCGGTCGGCATTGCCGTATCGACCGGTAAAGTTGCTGAGTCTGGCATTTATTACTTGATGAAATG
GGGAGCGATTTTGAGCATTAACCTCGGGATTGTCAACTTGTTGCCATTGCCGGCATTAGACGGTGGACGGCTCCTCTTTT
TCGCCATTGAGGCGGTGCGTGGCAAGCCGGTCGACCGCCAAAAAGAAGGAATGGTCCATTTTATCGGCTTCGCCTTGCTT
ATGTTACTTATGCTTGTCGTGACATGGAATGACATTCAAAAATTCTTCCTATAA

Upstream 100 bases:

>100_bases
ATCGCCTAGTGAGCGATCCGCAGCTTGAGGAGATTCGCGAAATCGACGCAGATACGCGCGCTTATGTTCGCTCACTACTA
TCGTAAAGGTGGTTGAAACT

Downstream 100 bases:

>100_bases
TGAAAGAGAGAAAACGAGGTGGCTATTGATGAGACAAAGTCAAGGGTTTATTCCGACATTGCGCGAAGTGCCGGCGGACG
CGGAAGTGAAAAGCCATCAG

Product: hypothetical protein

Products: NA

Alternate protein names: Regulating alternative sigma factor protease; Regulating anti-sigma-W factor activity protease [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
METIISFIVVFGALVFFHELGHLLLAKRAGILCREFAIGFGPKMFSFKKNETVYTVRLLPLGGFVRMAGEDPEMIELKRG
QVVGLLLDDEGQVEKIVINHKDDYPNIRVIEVEDADLEHGMYVTGYTDGERLERFAVKEPAFFVADRQEIQIAPYHRQFA
AKTLGQRTMAILAGPLANFVLALVVFILIGLLQGYPVDKPIIGELTPEGAARAAGLKQGDEVIAINGERMETWTEIVNTI
RAHPNEPLQFQIERGGNEMNVTVTPEEKTIQGETIGLIGVYQPMEKSVFGSVKQGLMETYYWTRQILVGLGQLITGQFQL
DMLSGPVGIAVSTGKVAESGIYYLMKWGAILSINLGIVNLLPLPALDGGRLLFFAIEAVRGKPVDRQKEGMVHFIGFALL
MLLMLVVTWNDIQKFFL

Sequences:

>Translated_417_residues
METIISFIVVFGALVFFHELGHLLLAKRAGILCREFAIGFGPKMFSFKKNETVYTVRLLPLGGFVRMAGEDPEMIELKRG
QVVGLLLDDEGQVEKIVINHKDDYPNIRVIEVEDADLEHGMYVTGYTDGERLERFAVKEPAFFVADRQEIQIAPYHRQFA
AKTLGQRTMAILAGPLANFVLALVVFILIGLLQGYPVDKPIIGELTPEGAARAAGLKQGDEVIAINGERMETWTEIVNTI
RAHPNEPLQFQIERGGNEMNVTVTPEEKTIQGETIGLIGVYQPMEKSVFGSVKQGLMETYYWTRQILVGLGQLITGQFQL
DMLSGPVGIAVSTGKVAESGIYYLMKWGAILSINLGIVNLLPLPALDGGRLLFFAIEAVRGKPVDRQKEGMVHFIGFALL
MLLMLVVTWNDIQKFFL
>Mature_417_residues
METIISFIVVFGALVFFHELGHLLLAKRAGILCREFAIGFGPKMFSFKKNETVYTVRLLPLGGFVRMAGEDPEMIELKRG
QVVGLLLDDEGQVEKIVINHKDDYPNIRVIEVEDADLEHGMYVTGYTDGERLERFAVKEPAFFVADRQEIQIAPYHRQFA
AKTLGQRTMAILAGPLANFVLALVVFILIGLLQGYPVDKPIIGELTPEGAARAAGLKQGDEVIAINGERMETWTEIVNTI
RAHPNEPLQFQIERGGNEMNVTVTPEEKTIQGETIGLIGVYQPMEKSVFGSVKQGLMETYYWTRQILVGLGQLITGQFQL
DMLSGPVGIAVSTGKVAESGIYYLMKWGAILSINLGIVNLLPLPALDGGRLLFFAIEAVRGKPVDRQKEGMVHFIGFALL
MLLMLVVTWNDIQKFFL

Specific function: Is responsible for Site-2 cleavage of the RsiW anti- sigma factor. This results, after a third proteolytic step catalyzed by the ClpXP protease, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor [

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=231, Percent_Identity=36.3636363636364, Blast_Score=148, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 46315; Mature: 46315

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METIISFIVVFGALVFFHELGHLLLAKRAGILCREFAIGFGPKMFSFKKNETVYTVRLLP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEECCCCEEEEEEEEE
LGGFVRMAGEDPEMIELKRGQVVGLLLDDEGQVEKIVINHKDDYPNIRVIEVEDADLEHG
CCCEEEECCCCCCEEEECCCCEEEEEECCCCCEEEEEEECCCCCCCEEEEEEECCCCCCC
MYVTGYTDGERLERFAVKEPAFFVADRQEIQIAPYHRQFAAKTLGQRTMAILAGPLANFV
EEEEECCCHHHHHHHHHCCCCEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
LALVVFILIGLLQGYPVDKPIIGELTPEGAARAAGLKQGDEVIAINGERMETWTEIVNTI
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEECCCHHHHHHHHHHHH
RAHPNEPLQFQIERGGNEMNVTVTPEEKTIQGETIGLIGVYQPMEKSVFGSVKQGLMETY
HCCCCCCEEEEEECCCCEEEEEECCCCCEECCCEEEEEECCCHHHHHHHHHHHHHHHHHH
YWTRQILVGLGQLITGQFQLDMLSGPVGIAVSTGKVAESGIYYLMKWGAILSINLGIVNL
HHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCHHHCCHHEEEECCCEEEEECCEEEE
LPLPALDGGRLLFFAIEAVRGKPVDRQKEGMVHFIGFALLMLLMLVVTWNDIQKFFL
ECCCCCCCCEEEEEEEEHHCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
METIISFIVVFGALVFFHELGHLLLAKRAGILCREFAIGFGPKMFSFKKNETVYTVRLLP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEECCCCEEEEEEEEE
LGGFVRMAGEDPEMIELKRGQVVGLLLDDEGQVEKIVINHKDDYPNIRVIEVEDADLEHG
CCCEEEECCCCCCEEEECCCCEEEEEECCCCCEEEEEEECCCCCCCEEEEEEECCCCCCC
MYVTGYTDGERLERFAVKEPAFFVADRQEIQIAPYHRQFAAKTLGQRTMAILAGPLANFV
EEEEECCCHHHHHHHHHCCCCEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
LALVVFILIGLLQGYPVDKPIIGELTPEGAARAAGLKQGDEVIAINGERMETWTEIVNTI
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEECCCHHHHHHHHHHHH
RAHPNEPLQFQIERGGNEMNVTVTPEEKTIQGETIGLIGVYQPMEKSVFGSVKQGLMETY
HCCCCCCEEEEEECCCCEEEEEECCCCCEECCCEEEEEECCCHHHHHHHHHHHHHHHHHH
YWTRQILVGLGQLITGQFQLDMLSGPVGIAVSTGKVAESGIYYLMKWGAILSINLGIVNL
HHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCHHHCCHHEEEECCCEEEEECCEEEE
LPLPALDGGRLLFFAIEAVRGKPVDRQKEGMVHFIGFALLMLLMLVVTWNDIQKFFL
ECCCCCCCCEEEEEEEEHHCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA