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The map label for this gene is murB [H]

Identifier: 138894478

GI number: 138894478

Start: 881166

End: 882143

Strand: Direct

Name: murB [H]

Synonym: GTNG_0808

Alternate gene names: 138894478

Gene position: 881166-882143 (Clockwise)

Preceding gene: 138894477

Following gene: 138894479

Centisome position: 24.82

GC content: 49.8

Gene sequence:

>978_bases
ATGGAAACAGTGCGTGATGAATGCGCTTGTCAGCATGGAATGAACGAAGAAGGTGACAGAAAGATGGAACGTGCGGAACA
CATTTATCAAAAACTTGTAGCTATTTGTGGAGAAGAGAATGTTTTGCGCGATGAGCCGATGAAACATCATACATTAGTGC
GGATCGGCGGCAAGGCTGATTTTCTCGTTTGGCCGGAAACGTACGAACAAGTCGTTGACGTGCTGCGGCTGAAAGAGGAG
TACGAGCTGCCGTTTACGCTTCTTGGCAACGGCTCCAATGTCATTATCCGCGATGGCGGGCTGCGCGGTATTGTTATGCA
GCTGAAGCATCTCAATCGCATTTGGCGCGAAGGGAACAACATCATCGCTCAAAGCGGAGCAGATATTAAGGCAGTGTCTC
GGTTTGCGCTGGAACAACATCTCACTGGTTTGGAGTTTGCCTGCGGCATCCCGGGATCGGTCGGCGGGGCGATTATGATG
AATGCCGGGGCTTACGGTGGAGAAGTGAAAGATGTGCTCGACCATGTGAAAGTGGCGACGCTTACTGGCGAGTTGAAGAC
GTTGACAAATGAGGAGCTCGAACTCGGATATCGAACGAGCTTGATTAGCCGGACACACGATATTGTGCTTGAAGTCGTGT
TTGCACTCCAGCCGGGTGATTATGGACAAATTAAAGCCAAAATGGATGATTTGACGTTTCAACGTGAATCAAAGCAGCCG
CTTGAATACCCGTCAGTCGGCAGCGTATTCAAGCGCCCGCCGGGCTATTTTGCCGGCAAGCTTATTCAAGACAGCGGCCT
GCAAGGGAAAGGGTTTGGCGGTGCGGAAGTGTCGACCAAGCACGCCGGGTTTATTATTAATAAAAACAATGCAACGGCTG
CCGATTACATTGCGACGATTGAAATGGTGCGCAAAACAGTGAAAGAAAAATTCGGCGTTGAACTTGAATTGGAAGTGAAA
ATTCTCGGCGAAGAGTGA

Upstream 100 bases:

>100_bases
TTTTTGGGCCGTTTCCATCCGCGTCACCTTTGGGCCTAGTCCGGAATAAAACAGAATAAGGAACATTGCCCACTTGATAT
GAGGCGCGTTTCCGGCGATA

Downstream 100 bases:

>100_bases
CACCTATCCGAACCCGATTGGCGGGTTCGGATTTTTTTATCATGTCGAACTGAGAAGATTCTCTTTTTCATGCGCAGGCA
TAACTTGCATCATCGAATCG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
METVRDECACQHGMNEEGDRKMERAEHIYQKLVAICGEENVLRDEPMKHHTLVRIGGKADFLVWPETYEQVVDVLRLKEE
YELPFTLLGNGSNVIIRDGGLRGIVMQLKHLNRIWREGNNIIAQSGADIKAVSRFALEQHLTGLEFACGIPGSVGGAIMM
NAGAYGGEVKDVLDHVKVATLTGELKTLTNEELELGYRTSLISRTHDIVLEVVFALQPGDYGQIKAKMDDLTFQRESKQP
LEYPSVGSVFKRPPGYFAGKLIQDSGLQGKGFGGAEVSTKHAGFIINKNNATAADYIATIEMVRKTVKEKFGVELELEVK
ILGEE

Sequences:

>Translated_325_residues
METVRDECACQHGMNEEGDRKMERAEHIYQKLVAICGEENVLRDEPMKHHTLVRIGGKADFLVWPETYEQVVDVLRLKEE
YELPFTLLGNGSNVIIRDGGLRGIVMQLKHLNRIWREGNNIIAQSGADIKAVSRFALEQHLTGLEFACGIPGSVGGAIMM
NAGAYGGEVKDVLDHVKVATLTGELKTLTNEELELGYRTSLISRTHDIVLEVVFALQPGDYGQIKAKMDDLTFQRESKQP
LEYPSVGSVFKRPPGYFAGKLIQDSGLQGKGFGGAEVSTKHAGFIINKNNATAADYIATIEMVRKTVKEKFGVELELEVK
ILGEE
>Mature_325_residues
METVRDECACQHGMNEEGDRKMERAEHIYQKLVAICGEENVLRDEPMKHHTLVRIGGKADFLVWPETYEQVVDVLRLKEE
YELPFTLLGNGSNVIIRDGGLRGIVMQLKHLNRIWREGNNIIAQSGADIKAVSRFALEQHLTGLEFACGIPGSVGGAIMM
NAGAYGGEVKDVLDHVKVATLTGELKTLTNEELELGYRTSLISRTHDIVLEVVFALQPGDYGQIKAKMDDLTFQRESKQP
LEYPSVGSVFKRPPGYFAGKLIQDSGLQGKGFGGAEVSTKHAGFIINKNNATAADYIATIEMVRKTVKEKFGVELELEVK
ILGEE

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 35991; Mature: 35991

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METVRDECACQHGMNEEGDRKMERAEHIYQKLVAICGEENVLRDEPMKHHTLVRIGGKAD
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEE
FLVWPETYEQVVDVLRLKEEYELPFTLLGNGSNVIIRDGGLRGIVMQLKHLNRIWREGNN
EEECCHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHCCCC
IIAQSGADIKAVSRFALEQHLTGLEFACGIPGSVGGAIMMNAGAYGGEVKDVLDHVKVAT
EEEECCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHE
LTGELKTLTNEELELGYRTSLISRTHDIVLEVVFALQPGDYGQIKAKMDDLTFQRESKQP
ECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHCCCCCCCC
LEYPSVGSVFKRPPGYFAGKLIQDSGLQGKGFGGAEVSTKHAGFIINKNNATAADYIATI
CCCCCCCHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHH
EMVRKTVKEKFGVELELEVKILGEE
HHHHHHHHHHHCCEEEEEEEEECCC
>Mature Secondary Structure
METVRDECACQHGMNEEGDRKMERAEHIYQKLVAICGEENVLRDEPMKHHTLVRIGGKAD
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEE
FLVWPETYEQVVDVLRLKEEYELPFTLLGNGSNVIIRDGGLRGIVMQLKHLNRIWREGNN
EEECCHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHCCCC
IIAQSGADIKAVSRFALEQHLTGLEFACGIPGSVGGAIMMNAGAYGGEVKDVLDHVKVAT
EEEECCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHE
LTGELKTLTNEELELGYRTSLISRTHDIVLEVVFALQPGDYGQIKAKMDDLTFQRESKQP
ECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHCCCCCCCC
LEYPSVGSVFKRPPGYFAGKLIQDSGLQGKGFGGAEVSTKHAGFIINKNNATAADYIATI
CCCCCCCHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHH
EMVRKTVKEKFGVELELEVKILGEE
HHHHHHHHHHHCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA