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The map label for this gene is phoR [H]

Identifier: 138894461

GI number: 138894461

Start: 865015

End: 866079

Strand: Reverse

Name: phoR [H]

Synonym: GTNG_0791

Alternate gene names: 138894461

Gene position: 866079-865015 (Counterclockwise)

Preceding gene: 138894462

Following gene: 138894448

Centisome position: 24.39

GC content: 48.83

Gene sequence:

>1065_bases
ATGAAACGATTATGGTTTGTGTTTAAATCCATCTTGACCGTGATCGCTGTGATGTCAATCATCTGCCTCTTTTGGTCTGC
GGCATATTTCATCACAGAAGCGATCTACACCCGATTCGCTTGGCAGCCGCATCCGCTCGTTCGGCAAATCATTTCATCGA
TCTTCGGCTTTTTGCTATTCGGGATGACCATGAGCGCGATCGGTCCTTTTTTGCGAAAGCGCGAAAGAGTATTTTGGCAC
CACTTAATAGACGCCATTAATCGAATCGCCAAAGGCGATTTTCGAGTGAATCTTCAGGTTGACTGGGGCGGACGGCATCA
TCCGTTTGCCGAACTCGTGACACGCATTAACGACATGGCCGCAAATTTGCAGGCCATGGAAGACATGCGTCAAGAATTTA
TTTCCAACGTTTCTCATGAGATTGGCTCTCCGCTAACATCGATTCGTGGATTTGCCCGCGCACTCAAAAACGAGAACTTA
AGCCAAGAGCAGCGGATGCATTATCTTGATATTATTGAAACTGAATGCGTAAGACTGTCAAAGCTAAGCGAGAATTTGCT
GCGGTTGGCGATGTTAGATTCTGAGCGCTACCCGCTTCATCCGACATCCTATCGTTTGGACACGCAATTACAAACGCTCA
TTCTTCACTGCGAGCCGCAGTGGGCGGAAAAAGACGTGGACATGTGTGCCGTGATGGAAAAAGTATCGATTACAGCTGAT
GAAGATTTGCTCAGTCAAGTGTGGCTGAACTTGATCCATAATGCCATCAAATTTACACCGAAAGGAGGAACAATCACCGT
CCAGGTTCAACGCCGTGGCGAACAAGCCATCGTCACGATTTCTGATACAGGGCCGGGAATTCCAAAGCATGACCAACCCC
GCATTTTTGAGCGGTTTTATAAAGTCGATAAATCCCGCCATCGCGCCGCAGGCGGCAGCGGGCTCGGCTTGGCGATCGCG
AAACAAATTGTGGATATGCACCATGGAACTATCTCCGTTCAGAGCGAGCCGGGAGAAGGAGCGACCTTTACAGTGGAACT
TCCCATTCGCGGTCCCTTTTCTTGA

Upstream 100 bases:

>100_bases
ATGTTCATATCAAGCGGCTGCGTGAACGGTTCGCTCAGCCGAACGTTCCCTTTTTCATCCGCACGATTCGTGGACTCGGC
TATCGGCTGGAGGCACGCCA

Downstream 100 bases:

>100_bases
CCTGTTTCTTACGGAGAAACAGGTCAAGAAGGGGGTTTTTTGTTCCGTGAACACATACGTTTCCAACCGTTGCTCATTTG
AGGGAAAACGTTGTGGAATC

Product: two component system histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MKRLWFVFKSILTVIAVMSIICLFWSAAYFITEAIYTRFAWQPHPLVRQIISSIFGFLLFGMTMSAIGPFLRKRERVFWH
HLIDAINRIAKGDFRVNLQVDWGGRHHPFAELVTRINDMAANLQAMEDMRQEFISNVSHEIGSPLTSIRGFARALKNENL
SQEQRMHYLDIIETECVRLSKLSENLLRLAMLDSERYPLHPTSYRLDTQLQTLILHCEPQWAEKDVDMCAVMEKVSITAD
EDLLSQVWLNLIHNAIKFTPKGGTITVQVQRRGEQAIVTISDTGPGIPKHDQPRIFERFYKVDKSRHRAAGGSGLGLAIA
KQIVDMHHGTISVQSEPGEGATFTVELPIRGPFS

Sequences:

>Translated_354_residues
MKRLWFVFKSILTVIAVMSIICLFWSAAYFITEAIYTRFAWQPHPLVRQIISSIFGFLLFGMTMSAIGPFLRKRERVFWH
HLIDAINRIAKGDFRVNLQVDWGGRHHPFAELVTRINDMAANLQAMEDMRQEFISNVSHEIGSPLTSIRGFARALKNENL
SQEQRMHYLDIIETECVRLSKLSENLLRLAMLDSERYPLHPTSYRLDTQLQTLILHCEPQWAEKDVDMCAVMEKVSITAD
EDLLSQVWLNLIHNAIKFTPKGGTITVQVQRRGEQAIVTISDTGPGIPKHDQPRIFERFYKVDKSRHRAAGGSGLGLAIA
KQIVDMHHGTISVQSEPGEGATFTVELPIRGPFS
>Mature_354_residues
MKRLWFVFKSILTVIAVMSIICLFWSAAYFITEAIYTRFAWQPHPLVRQIISSIFGFLLFGMTMSAIGPFLRKRERVFWH
HLIDAINRIAKGDFRVNLQVDWGGRHHPFAELVTRINDMAANLQAMEDMRQEFISNVSHEIGSPLTSIRGFARALKNENL
SQEQRMHYLDIIETECVRLSKLSENLLRLAMLDSERYPLHPTSYRLDTQLQTLILHCEPQWAEKDVDMCAVMEKVSITAD
EDLLSQVWLNLIHNAIKFTPKGGTITVQVQRRGEQAIVTISDTGPGIPKHDQPRIFERFYKVDKSRHRAAGGSGLGLAIA
KQIVDMHHGTISVQSEPGEGATFTVELPIRGPFS

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=33.0434782608696, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1788393, Length=269, Percent_Identity=28.6245353159851, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786783, Length=238, Percent_Identity=29.8319327731092, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1789149, Length=223, Percent_Identity=32.7354260089686, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI145693157, Length=239, Percent_Identity=30.1255230125523, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1790861, Length=308, Percent_Identity=29.2207792207792, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1788549, Length=326, Percent_Identity=28.5276073619632, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788713, Length=228, Percent_Identity=30.7017543859649, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787894, Length=265, Percent_Identity=28.3018867924528, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=31.981981981982, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI48994928, Length=228, Percent_Identity=32.4561403508772, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790346, Length=274, Percent_Identity=25.9124087591241, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786912, Length=224, Percent_Identity=29.9107142857143, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87082128, Length=319, Percent_Identity=28.2131661442006, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1790300, Length=231, Percent_Identity=30.7359307359307, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790551, Length=237, Percent_Identity=24.4725738396624, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI87081816, Length=353, Percent_Identity=26.628895184136, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788279, Length=223, Percent_Identity=27.3542600896861, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789403, Length=218, Percent_Identity=28.4403669724771, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789808, Length=238, Percent_Identity=25.2100840336134, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787374, Length=236, Percent_Identity=22.8813559322034, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=72, Percent_Identity=41.6666666666667, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40368; Mature: 40368

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLWFVFKSILTVIAVMSIICLFWSAAYFITEAIYTRFAWQPHPLVRQIISSIFGFLLF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GMTMSAIGPFLRKRERVFWHHLIDAINRIAKGDFRVNLQVDWGGRHHPFAELVTRINDMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHH
ANLQAMEDMRQEFISNVSHEIGSPLTSIRGFARALKNENLSQEQRMHYLDIIETECVRLS
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
KLSENLLRLAMLDSERYPLHPTSYRLDTQLQTLILHCEPQWAEKDVDMCAVMEKVSITAD
HHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCC
EDLLSQVWLNLIHNAIKFTPKGGTITVQVQRRGEQAIVTISDTGPGIPKHDQPRIFERFY
HHHHHHHHHHHHHHHHEECCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCCHHHHHHH
KVDKSRHRAAGGSGLGLAIAKQIVDMHHGTISVQSEPGEGATFTVELPIRGPFS
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKRLWFVFKSILTVIAVMSIICLFWSAAYFITEAIYTRFAWQPHPLVRQIISSIFGFLLF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GMTMSAIGPFLRKRERVFWHHLIDAINRIAKGDFRVNLQVDWGGRHHPFAELVTRINDMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHH
ANLQAMEDMRQEFISNVSHEIGSPLTSIRGFARALKNENLSQEQRMHYLDIIETECVRLS
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
KLSENLLRLAMLDSERYPLHPTSYRLDTQLQTLILHCEPQWAEKDVDMCAVMEKVSITAD
HHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCC
EDLLSQVWLNLIHNAIKFTPKGGTITVQVQRRGEQAIVTISDTGPGIPKHDQPRIFERFY
HHHHHHHHHHHHHHHHEECCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCCHHHHHHH
KVDKSRHRAAGGSGLGLAIAKQIVDMHHGTISVQSEPGEGATFTVELPIRGPFS
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]