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The map label for this gene is yacO [H]

Identifier: 138893766

GI number: 138893766

Start: 105819

End: 106559

Strand: Direct

Name: yacO [H]

Synonym: GTNG_0087

Alternate gene names: 138893766

Gene position: 105819-106559 (Clockwise)

Preceding gene: 138893765

Following gene: 138893767

Centisome position: 2.98

GC content: 57.22

Gene sequence:

>741_bases
ATGATGGAGTACATTATCGGCAGAAATCCGGTTATTGAAGCGCTCAAATCCGGGCGCGACATCAATAAAATTTGGATCGC
CGAAGGGGCACATCGTCACGCCGTCGAGCCCGTCCTCGACTGGGCGAAGCGGCGGGGGGTGATCGTCCAATATGTCCCGA
AGCGCAAGCTCGACCAAATGGCTGAAGGGGCGCACCAAGGAGTTATCGCCCAAGTGGCGGCGTACCGCTACTATGAGGTG
GATGACTTATTCGCCCGCGCCGCTGAACGCGGCGAGGCGCCGTTTTTCCTCGTGTTGGACGAGCTTGAGGATCCACATAA
TTTAGGGGCCATCATGCGTACAGCCGATGCGGTCGGGGCTCATGGTGTCATCATCCCGAAGCGGCGTTCAGTCGGGCTGA
CGCCAACGGTCGCAAAGGCGTCAACTGGAGCGATTGAGCACATTCCGGTTGCGCGTGTGACGAACTTGGCACGGACGATC
GACGAGTTGAAGGAGCGGGGAGTTTGGGTGGCCGGAACCGACGCAGCTGCCAAAGATGATTACCGTTCACTTGACGGTAC
GATGCCGTTGGCGCTTGTGATTGGCAGTGAGGGCAAAGGCATTAGCCGTTTAGTGCTCGAAAAGTGTGATTTTTTATTCC
GGCTGCCGATGCGCGGTCATGTCACCTCGCTCAACGCTTCCGTTGCCGCCAGCCTACTTATGTATGAGGTGTACCGGAAG
CGGTATCCATTAGGGGAATAG

Upstream 100 bases:

>100_bases
CGTTAATCGGGTACCATTTTTTAAGGAATGATGAGAAGCGAGTCGATGAGCTGATCGGCCGTTCATTTGCCATTATTGAA
AGGGAAGAAAGGGCGTTGGA

Downstream 100 bases:

>100_bases
CTGATGAACATTTTGATTGTTGACGGCTATAACATCATTGGGGCATGGCCGGTGCTGCGCCAGTTAAAAGAAGAGGGCGA
TCTAGCTGCAGCAAGGGATT

Product: 23S rRNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MMEYIIGRNPVIEALKSGRDINKIWIAEGAHRHAVEPVLDWAKRRGVIVQYVPKRKLDQMAEGAHQGVIAQVAAYRYYEV
DDLFARAAERGEAPFFLVLDELEDPHNLGAIMRTADAVGAHGVIIPKRRSVGLTPTVAKASTGAIEHIPVARVTNLARTI
DELKERGVWVAGTDAAAKDDYRSLDGTMPLALVIGSEGKGISRLVLEKCDFLFRLPMRGHVTSLNASVAASLLMYEVYRK
RYPLGE

Sequences:

>Translated_246_residues
MMEYIIGRNPVIEALKSGRDINKIWIAEGAHRHAVEPVLDWAKRRGVIVQYVPKRKLDQMAEGAHQGVIAQVAAYRYYEV
DDLFARAAERGEAPFFLVLDELEDPHNLGAIMRTADAVGAHGVIIPKRRSVGLTPTVAKASTGAIEHIPVARVTNLARTI
DELKERGVWVAGTDAAAKDDYRSLDGTMPLALVIGSEGKGISRLVLEKCDFLFRLPMRGHVTSLNASVAASLLMYEVYRK
RYPLGE
>Mature_246_residues
MMEYIIGRNPVIEALKSGRDINKIWIAEGAHRHAVEPVLDWAKRRGVIVQYVPKRKLDQMAEGAHQGVIAQVAAYRYYEV
DDLFARAAERGEAPFFLVLDELEDPHNLGAIMRTADAVGAHGVIIPKRRSVGLTPTVAKASTGAIEHIPVARVTNLARTI
DELKERGVWVAGTDAAAKDDYRSLDGTMPLALVIGSEGKGISRLVLEKCDFLFRLPMRGHVTSLNASVAASLLMYEVYRK
RYPLGE

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=265, Percent_Identity=31.6981132075472, Blast_Score=101, Evalue=6e-22,
Organism=Escherichia coli, GI1790623, Length=243, Percent_Identity=41.1522633744856, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1790083, Length=173, Percent_Identity=32.3699421965318, Blast_Score=88, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17555908, Length=255, Percent_Identity=29.8039215686275, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6324775, Length=287, Percent_Identity=25.0871080139373, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27157; Mature: 27157

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEYIIGRNPVIEALKSGRDINKIWIAEGAHRHAVEPVLDWAKRRGVIVQYVPKRKLDQM
CCCCCCCCCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEEEECCHHHHHHH
AEGAHQGVIAQVAAYRYYEVDDLFARAAERGEAPFFLVLDELEDPHNLGAIMRTADAVGA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCC
HGVIIPKRRSVGLTPTVAKASTGAIEHIPVARVTNLARTIDELKERGVWVAGTDAAAKDD
CCEEEECCCCCCCCCCHHCCCCCCHHHCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCH
YRSLDGTMPLALVIGSEGKGISRLVLEKCDFLFRLPMRGHVTSLNASVAASLLMYEVYRK
HHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHEECCCCCCEEHHHHHHHHHHHHHHHHHH
RYPLGE
HCCCCC
>Mature Secondary Structure
MMEYIIGRNPVIEALKSGRDINKIWIAEGAHRHAVEPVLDWAKRRGVIVQYVPKRKLDQM
CCCCCCCCCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEEEECCHHHHHHH
AEGAHQGVIAQVAAYRYYEVDDLFARAAERGEAPFFLVLDELEDPHNLGAIMRTADAVGA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCC
HGVIIPKRRSVGLTPTVAKASTGAIEHIPVARVTNLARTIDELKERGVWVAGTDAAAKDD
CCEEEECCCCCCCCCCHHCCCCCCHHHCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCH
YRSLDGTMPLALVIGSEGKGISRLVLEKCDFLFRLPMRGHVTSLNASVAASLLMYEVYRK
HHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHEECCCCCCEEHHHHHHHHHHHHHHHHHH
RYPLGE
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]