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The map label for this gene is radA [H]

Identifier: 138893758

GI number: 138893758

Start: 97410

End: 98783

Strand: Direct

Name: radA [H]

Synonym: GTNG_0079

Alternate gene names: 138893758

Gene position: 97410-98783 (Clockwise)

Preceding gene: 138893757

Following gene: 138893759

Centisome position: 2.74

GC content: 53.86

Gene sequence:

>1374_bases
ATGGCGAAAAAGAAAACAAAATTTGTTTGCCAAGAATGCGGGTATGAATCAGCGAAATGGCTCGGTCGTTGCCCGGGCTG
CCAAACGTGGAACTCGTTCGTTGAAGAAATCGAGCGGACAAAACCGGCTGTGCGCGGGGCGTTTCTTCATTCGGAACCAT
CGGGGCCAGCCAAACCGATTCCGATTACGGCTGTTACGGCAGCACAAGAGCCACGCATTGAAACGAAAAGTGTGGAGCTC
AATCGGGTGCTTGGCGGAGGAATCGTCAAAGGATCGCTCGTCTTAATCGGCGGTGATCCGGGTATTGGCAAATCGACGTT
ATTGCTGCAGACATCGGCACAGCTCGCTGCGGCCGGACATACGGTATTGTATATATCCGGTGAAGAGTCGGTGAAGCAAG
TGAAGCTGCGCGCTGGGCGTCTTCACGCTGAGTCTCATCAACTGTATGTGTTAGCAGAGGCGGATTTGGAATACATTGTA
ACAGCAATTGAAACGATTCAGCCTGCTTGTGTGATTGTCGATTCCATTCAGACGGTGTACCGAACGGATATCACATCGGC
GCCGGGCAGTGTTGCCCAAGTGCGCGAGTGCACCGCTGAGCTAATGAAAATCGCCAAGACGAAAGGCATTGCCATTTTCA
TTGTTGGCCATGTGACCAAAGAAGGGGCGATCGCCGGGCCGCGCCTGCTTGAGCATATGGTTGATACCGTTCTTTATTTT
GAAGGGGAGCGGCATCATACGTACCGCATTTTGCGGGCGGTGAAAAACCGCTTCGGTTCAACGAATGAAATCGGTATTTT
TGAAATGCGTGACATCGGGCTGCGCGAAGTAGAAAATCCGTCGGAAGTGTTTTTGGAAGAACGGTCGCGCGGGGCGGCCG
GCTCGACAGTTGTCGCGGCAATGGAGGGGACGCGTCCGGTGCTTGTTGAAATTCAGGCGCTCGTTTCGCCAACGAGTTTC
GGCAACCCGCGGCGGATGGCGACCGGCCTTGATCATAATCGCGTATCGCTGTTAATGGCTGTGCTCGAAAAGCGGGTCGG
GCTCCTGTTGCAAAACCAGGATGCTTACTTGAAAGTGGCAGGTGGAGTAAAGCTTGATGAACCGGCAATCGATTTGGCGG
TCGCCGTCAGCATTGCCTCGAGCTTCCGCGACCGGCCGACAAATCCAGCCGATGTCATTATCGGCGAAGTCGGCTTGACC
GGGGAAGTGCGCCGCGTTTCCCGCATTGAACAGCGCGTGCAAGAAGCCGTCAAATTAGGCTTTTCACGGGTCATTGTACC
AAAAAACAATTTGACTGGTTGGCAGCCGCCTGCAGGCGTCAATGTGATCGGTGTTTCGCATGTGGCCGAGGCGCTTGAGC
ATACGATGTTATAA

Upstream 100 bases:

>100_bases
TGTTGTCGAAACAGGCGGTCGTGTAAAGGAAAAAGGTATGCGGCAGCTTGCTGCCCATACCTTATTTTATATGGAACATG
TTGCAGAAAGGGTTAGACGG

Downstream 100 bases:

>100_bases
ACGATGTGAAAGGATCGAACCTTTTTGTCTTGCAGACGTAAAACATATAGTGAGAACCGAAGTGAATCGGGCGCTATACC
GACACCCACCGCTTATGATT

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MAKKKTKFVCQECGYESAKWLGRCPGCQTWNSFVEEIERTKPAVRGAFLHSEPSGPAKPIPITAVTAAQEPRIETKSVEL
NRVLGGGIVKGSLVLIGGDPGIGKSTLLLQTSAQLAAAGHTVLYISGEESVKQVKLRAGRLHAESHQLYVLAEADLEYIV
TAIETIQPACVIVDSIQTVYRTDITSAPGSVAQVRECTAELMKIAKTKGIAIFIVGHVTKEGAIAGPRLLEHMVDTVLYF
EGERHHTYRILRAVKNRFGSTNEIGIFEMRDIGLREVENPSEVFLEERSRGAAGSTVVAAMEGTRPVLVEIQALVSPTSF
GNPRRMATGLDHNRVSLLMAVLEKRVGLLLQNQDAYLKVAGGVKLDEPAIDLAVAVSIASSFRDRPTNPADVIIGEVGLT
GEVRRVSRIEQRVQEAVKLGFSRVIVPKNNLTGWQPPAGVNVIGVSHVAEALEHTML

Sequences:

>Translated_457_residues
MAKKKTKFVCQECGYESAKWLGRCPGCQTWNSFVEEIERTKPAVRGAFLHSEPSGPAKPIPITAVTAAQEPRIETKSVEL
NRVLGGGIVKGSLVLIGGDPGIGKSTLLLQTSAQLAAAGHTVLYISGEESVKQVKLRAGRLHAESHQLYVLAEADLEYIV
TAIETIQPACVIVDSIQTVYRTDITSAPGSVAQVRECTAELMKIAKTKGIAIFIVGHVTKEGAIAGPRLLEHMVDTVLYF
EGERHHTYRILRAVKNRFGSTNEIGIFEMRDIGLREVENPSEVFLEERSRGAAGSTVVAAMEGTRPVLVEIQALVSPTSF
GNPRRMATGLDHNRVSLLMAVLEKRVGLLLQNQDAYLKVAGGVKLDEPAIDLAVAVSIASSFRDRPTNPADVIIGEVGLT
GEVRRVSRIEQRVQEAVKLGFSRVIVPKNNLTGWQPPAGVNVIGVSHVAEALEHTML
>Mature_456_residues
AKKKTKFVCQECGYESAKWLGRCPGCQTWNSFVEEIERTKPAVRGAFLHSEPSGPAKPIPITAVTAAQEPRIETKSVELN
RVLGGGIVKGSLVLIGGDPGIGKSTLLLQTSAQLAAAGHTVLYISGEESVKQVKLRAGRLHAESHQLYVLAEADLEYIVT
AIETIQPACVIVDSIQTVYRTDITSAPGSVAQVRECTAELMKIAKTKGIAIFIVGHVTKEGAIAGPRLLEHMVDTVLYFE
GERHHTYRILRAVKNRFGSTNEIGIFEMRDIGLREVENPSEVFLEERSRGAAGSTVVAAMEGTRPVLVEIQALVSPTSFG
NPRRMATGLDHNRVSLLMAVLEKRVGLLLQNQDAYLKVAGGVKLDEPAIDLAVAVSIASSFRDRPTNPADVIIGEVGLTG
EVRRVSRIEQRVQEAVKLGFSRVIVPKNNLTGWQPPAGVNVIGVSHVAEALEHTML

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=456, Percent_Identity=46.2719298245614, Blast_Score=407, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 49414; Mature: 49283

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKKTKFVCQECGYESAKWLGRCPGCQTWNSFVEEIERTKPAVRGAFLHSEPSGPAKPI
CCCCHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHEEEEECCCCCCCCCC
PITAVTAAQEPRIETKSVELNRVLGGGIVKGSLVLIGGDPGIGKSTLLLQTSAQLAAAGH
CEEEEECCCCCCCCCCCEEEHHHHCCCEEECEEEEEECCCCCCCCEEEEEECHHHHHCCC
TVLYISGEESVKQVKLRAGRLHAESHQLYVLAEADLEYIVTAIETIQPACVIVDSIQTVY
EEEEEECCHHHHHHHHHHCCEECCCCEEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHH
RTDITSAPGSVAQVRECTAELMKIAKTKGIAIFIVGHVTKEGAIAGPRLLEHMVDTVLYF
HHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHEE
EGERHHTYRILRAVKNRFGSTNEIGIFEMRDIGLREVENPSEVFLEERSRGAAGSTVVAA
CCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHCCCHHHHHHHHHCCCCCCCEEEEE
MEGTRPVLVEIQALVSPTSFGNPRRMATGLDHNRVSLLMAVLEKRVGLLLQNQDAYLKVA
ECCCCCEEEEEEEHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCEEEECCCCEEEEE
GGVKLDEPAIDLAVAVSIASSFRDRPTNPADVIIGEVGLTGEVRRVSRIEQRVQEAVKLG
CCCEECCCHHHHHHHHHHHHHHCCCCCCCHHEEEECCCCCHHHHHHHHHHHHHHHHHHCC
FSRVIVPKNNLTGWQPPAGVNVIGVSHVAEALEHTML
CCEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHCC
>Mature Secondary Structure 
AKKKTKFVCQECGYESAKWLGRCPGCQTWNSFVEEIERTKPAVRGAFLHSEPSGPAKPI
CCCHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHEEEEECCCCCCCCCC
PITAVTAAQEPRIETKSVELNRVLGGGIVKGSLVLIGGDPGIGKSTLLLQTSAQLAAAGH
CEEEEECCCCCCCCCCCEEEHHHHCCCEEECEEEEEECCCCCCCCEEEEEECHHHHHCCC
TVLYISGEESVKQVKLRAGRLHAESHQLYVLAEADLEYIVTAIETIQPACVIVDSIQTVY
EEEEEECCHHHHHHHHHHCCEECCCCEEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHH
RTDITSAPGSVAQVRECTAELMKIAKTKGIAIFIVGHVTKEGAIAGPRLLEHMVDTVLYF
HHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHEE
EGERHHTYRILRAVKNRFGSTNEIGIFEMRDIGLREVENPSEVFLEERSRGAAGSTVVAA
CCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHCCCHHHHHHHHHCCCCCCCEEEEE
MEGTRPVLVEIQALVSPTSFGNPRRMATGLDHNRVSLLMAVLEKRVGLLLQNQDAYLKVA
ECCCCCEEEEEEEHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCEEEECCCCEEEEE
GGVKLDEPAIDLAVAVSIASSFRDRPTNPADVIIGEVGLTGEVRRVSRIEQRVQEAVKLG
CCCEECCCHHHHHHHHHHHHHHCCCCCCCHHEEEECCCCCHHHHHHHHHHHHHHHHHHCC
FSRVIVPKNNLTGWQPPAGVNVIGVSHVAEALEHTML
CCEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 8016066 [H]