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The map label for this gene is folB [H]

Identifier: 138893749

GI number: 138893749

Start: 82396

End: 82785

Strand: Direct

Name: folB [H]

Synonym: GTNG_0070

Alternate gene names: 138893749

Gene position: 82396-82785 (Clockwise)

Preceding gene: 138893748

Following gene: 138893750

Centisome position: 2.32

GC content: 51.54

Gene sequence:

>390_bases
ATGCGATGCTTGGGAAAGGGGAGAGCGGCCATCGATAAAATCTATGTGCGAGAGATGGAGTTTTATGGCTATCATGGAGT
GCTTCCCGAAGAAAATGTCCTCGGTCAGAAGTTCGTGATTGATGTGACGATGGAGCTTGATTTGCGGCCAGCTGGGCGGA
GTGATTGTCTTGAGCATACGATCAACTATGCGGATGTGTACGAGCGTTGTCGGACGATTGTTGAGGAGCGGACATTTGCT
TTGATCGAGGCAGTGGCTGAGGCGATCGCCGATGATCTGCTTGCCGCTTTTCCTGCCATTCAGCGTTGTACCGTGAGGGT
GACGAAGCCAAATCCACCAATCCGCGGACATTACAAGCATGTCGCCGTTGAAATTGTTAGGGGGCGTTAA

Upstream 100 bases:

>100_bases
GAAGGAACGGGAGCTACTGTTTGTCTTGGTATCGTGAAAGGGGCGAATATCGTCCGCGTTCACGATGTATTGCCGATCGC
CCGCATGGCGAAAATGATGG

Downstream 100 bases:

>100_bases
ATGGAAAACATTGTATATATTTCCTTAGGTTCTAACTTAGGGGATCGTGTCTATTATTTACGTTCGGCCATTGAAGCACT
TGATCGCTACGAGGGAATTT

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MRCLGKGRAAIDKIYVREMEFYGYHGVLPEENVLGQKFVIDVTMELDLRPAGRSDCLEHTINYADVYERCRTIVEERTFA
LIEAVAEAIADDLLAAFPAIQRCTVRVTKPNPPIRGHYKHVAVEIVRGR

Sequences:

>Translated_129_residues
MRCLGKGRAAIDKIYVREMEFYGYHGVLPEENVLGQKFVIDVTMELDLRPAGRSDCLEHTINYADVYERCRTIVEERTFA
LIEAVAEAIADDLLAAFPAIQRCTVRVTKPNPPIRGHYKHVAVEIVRGR
>Mature_129_residues
MRCLGKGRAAIDKIYVREMEFYGYHGVLPEENVLGQKFVIDVTMELDLRPAGRSDCLEHTINYADVYERCRTIVEERTFA
LIEAVAEAIADDLLAAFPAIQRCTVRVTKPNPPIRGHYKHVAVEIVRGR

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

Organism=Escherichia coli, GI87082204, Length=119, Percent_Identity=33.6134453781513, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 14661; Mature: 14661

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCLGKGRAAIDKIYVREMEFYGYHGVLPEENVLGQKFVIDVTMELDLRPAGRSDCLEHT
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHH
INYADVYERCRTIVEERTFALIEAVAEAIADDLLAAFPAIQRCTVRVTKPNPPIRGHYKH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHH
VAVEIVRGR
EEEEEECCC
>Mature Secondary Structure
MRCLGKGRAAIDKIYVREMEFYGYHGVLPEENVLGQKFVIDVTMELDLRPAGRSDCLEHT
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHH
INYADVYERCRTIVEERTFALIEAVAEAIADDLLAAFPAIQRCTVRVTKPNPPIRGHYKH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHH
VAVEIVRGR
EEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]