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The map label for this gene is tsf [H]

Identifier: 13508370

GI number: 13508370

Start: 757870

End: 758766

Strand: Direct

Name: tsf [H]

Synonym: MPN631

Alternate gene names: 13508370

Gene position: 757870-758766 (Clockwise)

Preceding gene: 13508365

Following gene: 13508371

Centisome position: 92.83

GC content: 40.25

Gene sequence:

>897_bases
ATGGCAACAAAAATAGAGCTCATAAAAGAACTACGTAAAACAACACAAGCGAGCATGATGGACTGTAAAAAGGCTTTGGA
ACAAAATAACGATGATCTCGAAAAGGCCATTAAGTGATTGAGAGAAAACGGAATTGTTAAATCTGCTAAGAAATTAGGCA
AAGTAGCCGCTGATGGTTGCATTGTGTTACACAGCGATCACCACAAGGCAGTGATGGTGGAAATTAATTCTCAAACGGAC
TTTGTAGCGCGTAGTCAAGAGTTAACGGACTTTGCGCAATTAATGATTAGTGAAGTCTTTAAAAAGGCTACCCCTACCAC
TACTATTGAAGAAGTAACCCAGTACGAACTCCAAGGCAAAGAAAAGGTAGCAGAACGTTTGGCTTTAGTCGCTTCCAAAA
CTGATGAAAAGATTGTGTTGCGCCGCTTAATGGTGTTTGAAAGCAAAACTAACCACATCTTTAGCTACCTCCACGCTAAC
AAACGGATTGGCGTAATCTTGGAAGTGGAAGGCAAGTTTGATGAACAAGATGGTAAACACTTAGCAATGCACATTGCCGC
TAACTCACCGCAGTTCATTGATCAGGACAATGTGGATCAAACATGGTTAGCTAACGAAACCAGCATCATTAAGTCCCAAG
CCAAACTAGAAGTCCAAGACAATCCGAAGAAAGCAGCGTTCTTAGACAAAACTATTGCTGGACGCGTGAACAAACTCTTA
ATTGACATTTGTCTGGTAAACCAAAAGTACTTGGTCGATGAATCCAAAACAGTTGGTCAATTCTTAAAGGAAAAGAACAG
TAAAGTAATCCATTTTGTGCGCTTTGAAGTTGGTGAAGGCATTGTCAAAGAAGCAGTTGACTTCGCTAGTGAAGTAAGTG
CGCAAATGAAAAAATAA

Upstream 100 bases:

>100_bases
TTTTTATCTTGCATATTCCAAGTCCTCCTTTTTCATCATTTTGCCAATTGCTAACAGGCTTAAATTTAATATTTATTAGG
TACAAAAATCGATTACATTA

Downstream 100 bases:

>100_bases
GATGCGCCTAAAGATCCTAATCAAACTAAGCGGTGCTGGCATGAGCGCTGATAGTTCCGAACCGTTTTCCAACCAATTTT
TAGAAACTGTCATCGCTCAA

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MATKIELIKELRKTTQASMMDCKKALEQNNDDLEKAIKWLRENGIVKSAKKLGKVAADGCIVLHSDHHKAVMVEINSQTD
FVARSQELTDFAQLMISEVFKKATPTTTIEEVTQYELQGKEKVAERLALVASKTDEKIVLRRLMVFESKTNHIFSYLHAN
KRIGVILEVEGKFDEQDGKHLAMHIAANSPQFIDQDNVDQTWLANETSIIKSQAKLEVQDNPKKAAFLDKTIAGRVNKLL
IDICLVNQKYLVDESKTVGQFLKEKNSKVIHFVRFEVGEGIVKEAVDFASEVSAQMKK

Sequences:

>Translated_298_residues
MATKIELIKELRKTTQASMMDCKKALEQNNDDLEKAIK*LRENGIVKSAKKLGKVAADGCIVLHSDHHKAVMVEINSQTD
FVARSQELTDFAQLMISEVFKKATPTTTIEEVTQYELQGKEKVAERLALVASKTDEKIVLRRLMVFESKTNHIFSYLHAN
KRIGVILEVEGKFDEQDGKHLAMHIAANSPQFIDQDNVDQTWLANETSIIKSQAKLEVQDNPKKAAFLDKTIAGRVNKLL
IDICLVNQKYLVDESKTVGQFLKEKNSKVIHFVRFEVGEGIVKEAVDFASEVSAQMKK
>Mature_297_residues
ATKIELIKELRKTTQASMMDCKKALEQNNDDLEKAIK*LRENGIVKSAKKLGKVAADGCIVLHSDHHKAVMVEINSQTDF
VARSQELTDFAQLMISEVFKKATPTTTIEEVTQYELQGKEKVAERLALVASKTDEKIVLRRLMVFESKTNHIFSYLHANK
RIGVILEVEGKFDEQDGKHLAMHIAANSPQFIDQDNVDQTWLANETSIIKSQAKLEVQDNPKKAAFLDKTIAGRVNKLLI
DICLVNQKYLVDESKTVGQFLKEKNSKVIHFVRFEVGEGIVKEAVDFASEVSAQMKK

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome [H]

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family [H]

Homologues:

Organism=Homo sapiens, GI171846268, Length=292, Percent_Identity=26.3698630136986, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786366, Length=294, Percent_Identity=41.4965986394558, Blast_Score=190, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI17561440, Length=303, Percent_Identity=27.0627062706271, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449 [H]

Pfam domain/function: PF00889 EF_TS; PF00627 UBA [H]

EC number: NA

Molecular weight: Translated: 33441; Mature: 33310

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS01126 EF_TS_1 ; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATKIELIKELRKTTQASMMDCKKALEQNNDDLEKAIKLRENGIVKSAKKLGKVAADGCI
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCEE
VLHSDHHKAVMVEINSQTDFVARSQELTDFAQLMISEVFKKATPTTTIEEVTQYELQGKE
EEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHH
KVAERLALVASKTDEKIVLRRLMVFESKTNHIFSYLHANKRIGVILEVEGKFDEQDGKHL
HHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEE
AMHIAANSPQFIDQDNVDQTWLANETSIIKSQAKLEVQDNPKKAAFLDKTIAGRVNKLLI
EEEEECCCCCCCCCCCCCCHHCCCCHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHH
DICLVNQKYLVDESKTVGQFLKEKNSKVIHFVRFEVGEGIVKEAVDFASEVSAQMKK
HHHHCCCHHCCCCHHHHHHHHHHCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATKIELIKELRKTTQASMMDCKKALEQNNDDLEKAIKLRENGIVKSAKKLGKVAADGCI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCEE
VLHSDHHKAVMVEINSQTDFVARSQELTDFAQLMISEVFKKATPTTTIEEVTQYELQGKE
EEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHH
KVAERLALVASKTDEKIVLRRLMVFESKTNHIFSYLHANKRIGVILEVEGKFDEQDGKHL
HHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEE
AMHIAANSPQFIDQDNVDQTWLANETSIIKSQAKLEVQDNPKKAAFLDKTIAGRVNKLLI
EEEEECCCCCCCCCCCCCCHHCCCCHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHH
DICLVNQKYLVDESKTVGQFLKEKNSKVIHFVRFEVGEGIVKEAVDFASEVSAQMKK
HHHHCCCHHCCCCHHHHHHHHHHCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]