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The map label for this gene is oppD [H]

Identifier: 13507956

GI number: 13507956

Start: 268204

End: 269475

Strand: Direct

Name: oppD [H]

Synonym: MPN217

Alternate gene names: 13507956

Gene position: 268204-269475 (Clockwise)

Preceding gene: 13507955

Following gene: 13507957

Centisome position: 32.85

GC content: 44.65

Gene sequence:

>1272_bases
ATGGCACTAAAAGCAACTAATTTTTTTACAGAACCAGAGTACAAACTGCAGGATGATTTGATCTTAGATATCCGTGATCT
TCACGTGAGTTTTAAGGTTAAAGACGGCATTATGCAAGCTGTCCGTGGTGTTGATCTCAAAGTCAAAAAGGGCTCCATTG
TCGGCATTGTGGGCGAATCTGGTAGTGGTAAATCGGTCTGTGTTAAGTCGATTATTGGCTTTAACGATGGCGCAAAAACG
ACCGCTAAGTTAATGAACTTTAAGAACATTGACATTAGCAAGATGAAAAAGCACCAGTGACAGTACTACCGTGGCACGTA
CGTGTCTTACATTTCCCAAGATCCACTGTTCTCGTTAAACCCCACCATGACCATCGGTCGCCAGGTTAAAGAAGCGATTT
ATGTGTCGTGTAAGCGCCGATATTACCAAACTAAGAGTGACCTCAAATACGATTTGCAAACAGAACGAATTGACCTGGAC
ACTTACAAGGAAAAACTAGCACAAGCCAAGGAAACTTACAAAGCTAAAACGACTAAGGCGGCGGTCCATGCAAAAACGCT
AGAAATCCTTAACTTCATTGGCATTGACCAAGCTGAAAAGCGCTTAAAGGCCTTTCCAAGTGAGTTTTCCGGGGGAATGC
GGCAACGGATTGTGATCGCGATTGCCGTAGCCACCGAACCGGATTTAATTATTGCCGATGAACCGACCACGGCGTTGGAT
GTGACCATCCAAGCGAAGGCGTTGAACCTAATTAAACAGCTGCGTGACCTGCTCAACATTACCATTATTTTTATTAGTCA
CAACATCTCGTTAATTGCTAATTTCTGTGACTTTGTATACGTAATGTACGCTGGTCGATTAGTGGAAAAGGGCTTAGTTG
AGGAAATCTTTACCAATCCGGTGCACCCCTACACTTGGGCATTAATGGCTTCTATCCCTGAAGGTACGGACAAAAACGCT
CCGCTAACCTCAATTCCTGGGTATATTCCCAATATGTTATCCCCGCCTAAGGGCGATGCCTTTGCAGCGCGGAACCAGTT
TGCACTTGCCATTGATTTCGAGCACCAACCGCCGTTCTTTGATGTAACGGAAACTCATAAGGCCGCTACCTGGCTACTCC
ATCCCCAAGCACCGAAGGTAGAGATGCCCGCCGATGTCAAGGAAAAGATTGCCATTACCCGCAAAGCACTCGCCATTAAA
ATGCCATCTCAACCTGTAAAACAACCAAAAAGCAATGGAAACAAAAAAACAAAAACAAAATCCGCTCGTTAA

Upstream 100 bases:

>100_bases
ACCAGCTCAATTGTGAGCTTTGCAATTCTCACCGTTTCGACCCGCGTGTTTGCTAACGCTTTAAATGACGCAATTGACCC
ACGGGTAATAAGGAGGTAAT

Downstream 100 bases:

>100_bases
TGTTAAAGCCTTGAGCATGTTGTTCAAGGTCCGCGGTAGCTTCTTTAAAGCCTTAGATGAAATTGACTTTACCGTCAATG
AAGGTGACTTCTTTGGGGTC

Product: peptide ABC transporter ATP-binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MALKATNFFTEPEYKLQDDLILDIRDLHVSFKVKDGIMQAVRGVDLKVKKGSIVGIVGESGSGKSVCVKSIIGFNDGAKT
TAKLMNFKNIDISKMKKHQWQYYRGTYVSYISQDPLFSLNPTMTIGRQVKEAIYVSCKRRYYQTKSDLKYDLQTERIDLD
TYKEKLAQAKETYKAKTTKAAVHAKTLEILNFIGIDQAEKRLKAFPSEFSGGMRQRIVIAIAVATEPDLIIADEPTTALD
VTIQAKALNLIKQLRDLLNITIIFISHNISLIANFCDFVYVMYAGRLVEKGLVEEIFTNPVHPYTWALMASIPEGTDKNA
PLTSIPGYIPNMLSPPKGDAFAARNQFALAIDFEHQPPFFDVTETHKAATWLLHPQAPKVEMPADVKEKIAITRKALAIK
MPSQPVKQPKSNGNKKTKTKSAR

Sequences:

>Translated_423_residues
MALKATNFFTEPEYKLQDDLILDIRDLHVSFKVKDGIMQAVRGVDLKVKKGSIVGIVGESGSGKSVCVKSIIGFNDGAKT
TAKLMNFKNIDISKMKKHQ*QYYRGTYVSYISQDPLFSLNPTMTIGRQVKEAIYVSCKRRYYQTKSDLKYDLQTERIDLD
TYKEKLAQAKETYKAKTTKAAVHAKTLEILNFIGIDQAEKRLKAFPSEFSGGMRQRIVIAIAVATEPDLIIADEPTTALD
VTIQAKALNLIKQLRDLLNITIIFISHNISLIANFCDFVYVMYAGRLVEKGLVEEIFTNPVHPYTWALMASIPEGTDKNA
PLTSIPGYIPNMLSPPKGDAFAARNQFALAIDFEHQPPFFDVTETHKAATWLLHPQAPKVEMPADVKEKIAITRKALAIK
MPSQPVKQPKSNGNKKTKTKSAR
>Mature_422_residues
ALKATNFFTEPEYKLQDDLILDIRDLHVSFKVKDGIMQAVRGVDLKVKKGSIVGIVGESGSGKSVCVKSIIGFNDGAKTT
AKLMNFKNIDISKMKKHQ*QYYRGTYVSYISQDPLFSLNPTMTIGRQVKEAIYVSCKRRYYQTKSDLKYDLQTERIDLDT
YKEKLAQAKETYKAKTTKAAVHAKTLEILNFIGIDQAEKRLKAFPSEFSGGMRQRIVIAIAVATEPDLIIADEPTTALDV
TIQAKALNLIKQLRDLLNITIIFISHNISLIANFCDFVYVMYAGRLVEKGLVEEIFTNPVHPYTWALMASIPEGTDKNAP
LTSIPGYIPNMLSPPKGDAFAARNQFALAIDFEHQPPFFDVTETHKAATWLLHPQAPKVEMPADVKEKIAITRKALAIKM
PSQPVKQPKSNGNKKTKTKSAR

Specific function: Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system [H]

COG id: COG0444

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI48994883, Length=362, Percent_Identity=33.9779005524862, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1787759, Length=359, Percent_Identity=34.5403899721448, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1789963, Length=329, Percent_Identity=35.258358662614, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1787500, Length=340, Percent_Identity=34.1176470588235, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1787548, Length=332, Percent_Identity=32.8313253012048, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI145693107, Length=319, Percent_Identity=34.7962382445141, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1789962, Length=357, Percent_Identity=31.3725490196078, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1788506, Length=297, Percent_Identity=33.3333333333333, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1787758, Length=304, Percent_Identity=31.9078947368421, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1789890, Length=271, Percent_Identity=30.6273062730627, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI48994997, Length=272, Percent_Identity=28.6764705882353, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789891, Length=270, Percent_Identity=26.6666666666667, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787547, Length=295, Percent_Identity=24.406779661017, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1788225, Length=269, Percent_Identity=28.6245353159851, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786398, Length=144, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788761, Length=303, Percent_Identity=22.1122112211221, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87081791, Length=324, Percent_Identity=24.0740740740741, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1789032, Length=279, Percent_Identity=25.4480286738351, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787712, Length=275, Percent_Identity=24.3636363636364, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787370, Length=268, Percent_Identity=23.5074626865672, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786345, Length=302, Percent_Identity=24.1721854304636, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788644, Length=126, Percent_Identity=30.952380952381, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787029, Length=264, Percent_Identity=25, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790162, Length=144, Percent_Identity=30.5555555555556, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788450, Length=271, Percent_Identity=22.8782287822878, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081834, Length=228, Percent_Identity=25.4385964912281, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081709, Length=286, Percent_Identity=21.3286713286713, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789672, Length=278, Percent_Identity=23.021582733813, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787089, Length=96, Percent_Identity=36.4583333333333, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790739, Length=92, Percent_Identity=33.695652173913, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786253, Length=255, Percent_Identity=23.921568627451, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789586, Length=296, Percent_Identity=23.3108108108108, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786872, Length=135, Percent_Identity=29.6296296296296, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28574533, Length=269, Percent_Identity=24.1635687732342, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 47203; Mature: 47072

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALKATNFFTEPEYKLQDDLILDIRDLHVSFKVKDGIMQAVRGVDLKVKKGSIVGIVGES
CCEECCCCCCCCCCCCCCCEEEEEEEEEEEEEEHHHHHHHHCCCCEEEECCCEEEEEECC
GSGKSVCVKSIIGFNDGAKTTAKLMNFKNIDISKMKKHQQYYRGTYVSYISQDPLFSLNP
CCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCEECCC
TMTIGRQVKEAIYVSCKRRYYQTKSDLKYDLQTERIDLDTYKEKLAQAKETYKAKTTKAA
CHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHH
VHAKTLEILNFIGIDQAEKRLKAFPSEFSGGMRQRIVIAIAVATEPDLIIADEPTTALDV
HHHHHHHHHHHHCCCHHHHHHHHCCHHHCCCCCEEEEEEEEEECCCCEEEECCCCCEEEE
TIQAKALNLIKQLRDLLNITIIFISHNISLIANFCDFVYVMYAGRLVEKGLVEEIFTNPV
EEHHHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HPYTWALMASIPEGTDKNAPLTSIPGYIPNMLSPPKGDAFAARNQFALAIDFEHQPPFFD
CHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCEEEEEEECCCCCCCC
VTETHKAATWLLHPQAPKVEMPADVKEKIAITRKALAIKMPSQPVKQPKSNGNKKTKTKS
CCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHEEEECCCCHHCCCCCCCCCCCCCCC
AR
CC
>Mature Secondary Structure 
ALKATNFFTEPEYKLQDDLILDIRDLHVSFKVKDGIMQAVRGVDLKVKKGSIVGIVGES
CEECCCCCCCCCCCCCCCEEEEEEEEEEEEEEHHHHHHHHCCCCEEEECCCEEEEEECC
GSGKSVCVKSIIGFNDGAKTTAKLMNFKNIDISKMKKHQQYYRGTYVSYISQDPLFSLNP
CCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCEECCC
TMTIGRQVKEAIYVSCKRRYYQTKSDLKYDLQTERIDLDTYKEKLAQAKETYKAKTTKAA
CHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHH
VHAKTLEILNFIGIDQAEKRLKAFPSEFSGGMRQRIVIAIAVATEPDLIIADEPTTALDV
HHHHHHHHHHHHCCCHHHHHHHHCCHHHCCCCCEEEEEEEEEECCCCEEEECCCCCEEEE
TIQAKALNLIKQLRDLLNITIIFISHNISLIANFCDFVYVMYAGRLVEKGLVEEIFTNPV
EEHHHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HPYTWALMASIPEGTDKNAPLTSIPGYIPNMLSPPKGDAFAARNQFALAIDFEHQPPFFD
CHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCEEEEEEECCCCCCCC
VTETHKAATWLLHPQAPKVEMPADVKEKIAITRKALAIKMPSQPVKQPKSNGNKKTKTKS
CCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHEEEECCCCHHCCCCCCCCCCCCCCC
AR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]