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The map label for this gene is secA [H]

Identifier: 13507949

GI number: 13507949

Start: 257240

End: 259666

Strand: Direct

Name: secA [H]

Synonym: MPN210

Alternate gene names: 13507949

Gene position: 257240-259666 (Clockwise)

Preceding gene: 13507948

Following gene: 13507950

Centisome position: 31.51

GC content: 46.81

Gene sequence:

>2427_bases
ATGGGTCTGTTTAACTTCTTGAAGTTAGTCTCCCCGCGTCATCGGATTTACCATAAGGCAAGTAAGATTGCCAACGAAGT
CGAGGGACACAAAAATTACTACCGCAACCTCACTGATGTACAGCTGCTGGAAGAGTCCAATAAGCTAGTGGATTTAGTGA
CAAAGCAAAACTACACCATTTTGGATGTGGCGGTGGCTGCTTTGGCCTTAATTCGCGAAGTGGTCTACCGTGAAACCGGG
GAGTTTGCTTACAGAGTGCAAATTATTGGTGCTTACATCGTCTTGATCGGTGACTTTGCTGAAATGATGACTGGGGAAGG
GAAAACCCTGACCATTGTTTTAGCAGCCTATGTCTCGGCGTTAGAAAAACGCGGTGTCCATGTGGTTACGGTCAATGAAT
ACCTAGCGCAGCGGGATGCTACTAACGCCACCAAGATCTTAAAGCGTGTTGGCATGACCGTTGGTTGTAACTTTGCTAAC
CTAGCACCACATTTAAAGCAAGCCGCGTTTGCTTGTGATGTAACTTACACCACTAACAGTGAACTCGGTTTTGATTACCT
CAGGGACAATATGGTGCACCGCTTTGAGGACAAGAAGATCCGCGAGTTGCACTTTGCGATAGTAGACGAAGGCGATTCGG
TTCTCATTGATGAAGCGCGCACCCCTTTAATTATTTCTGGTCCTGCCAAAAACGAGTTTGCAGCATACGTGGCTGTTGAT
CGCTTTGTCAAAAAGCTCAAGGAAGACGAGTACAAGATTGACCCCGAATCACGTGCCCCCGCTTTAACAGAACTTGGCAT
TAAGCACGCGGAAAAGAACTTTAAAACCGATAACCTGTTTGCGCTAGAAAACAGTGACCTGTTCCACAAGATTATTAACG
CTTTAACCGCCGTTAAAGTTTTTGAGCAGGGCAAGGAGTACATTGTGCGTGATGGTAAGGTGTTAATTGTGGACCACTTT
ACTGGCCGAATCCTGGAGGGCAGGAGCTACAGTAATGGGCTCCACCAAGCGGTTCAGGCCAAGGAAATGGTCGAAATTGA
ACCAGAAAATGTGATAGTAGCTACGATTACCTACCAATCGTTTTTCCGTCTGTACAACCGGTTGTCAGCGGTATCGGGTA
CCGCTTTTACTGAATCGGAGGAATTCCTCAAGATTTACAACATGGTGGTAGTACCCGTACCTACTAACCGACCCAATATC
CGCAAAGACCGTGCTGACAGCGTCTTTGGTACGCCCAACATTAAGTGGCTAGCAGTGGTCAAGGAAGTCAAACGGATCCA
CGAAACCGGGCGACCAATCCTAATTGGGACCGCCAACATTGATGACTCGGAACTACTTCACAACTACCTCCAAGAAGCCA
ACATTCCCCACGAAGTTCTCAACGCCAAGAACCACTCTCGGGAAGCGGAAATAGTCGCTAAGGCGGGCCAAAAAGGGGCG
GTGACCATTTCTACCAATATGGCGGGAAGAGGTACTGACATTCGTTTAGGTGAAGGGGTCGCTGAAATGGGCGGGTTGTA
TGTCCTTGGTACGGAACGCAACGAATCGCGCCGGATTGACAACCAACTGCGCGGTCGGGCGGGTCGGCAAGGCGATCGCG
GTGAGACCAAGTTCTTTATCTCCTTGGGTGATGCCCTGTTCAAACGCTTTGCCCATGACCGGATTGAACGCGCCATTACT
AAGTTAGGGAACGATACCTTTGACAGCTCCTTCTTTTCCAAGATGTTAAGCCGTACCCAAAAACGGGTCGAAGCAATTAA
CTTTGACACCAGAAAGAACTTAATTGATTATGACCATGTGTTGGCCAGTCAACGGGAATTGATCTACAAACAACGCGATA
AGTTCTTATTAGCCACTGATCTCAGTGACATGATCGACAAGATGTTGGAAAAGTTTGTCGAGCAGTTCTGTGACCAGTAC
CGCAACCCTAAGAACCAAAACCTCGTTAACCACATTGCTTTATCAGAGGCCTTAAACCTGGAATTAAACATGCACGGTGT
TATTAGTCCGAAGCTGTTTGAAAACATGACTTTTGATGCGACTGTCCATAAAACCCACAGTTTAATTGGTGAAAAGATTA
CCAATAAGGTCAAGGTCTTAACCCCCCCAATTGCCCTCATCCGTTTTCGTGAAATTATGATCACAGCAATGGACAAGCAC
TGAATCGAACACTTAGACAATGTCTTTAAGCTCAGGGAAGGGGTTACCTTGCGCTCGATGGAACAAACGAGTCCCCTCAA
CGTTTACATTCGCGAAACCGACATCTTGTTCCAAACAATGTTGCAAAAGATTGCTCGGGACGTCATTATCCAAATTGCTA
ACTTAGCGACTCCCGAAGAGTTTGATGAGGAACTAATGAAGGCTAACGCCTTGAAGAAGTTGCAAGCACTTAGAGAAGCT
CATGAAAAGTCCAACGAAGGACAGTAA

Upstream 100 bases:

>100_bases
AAAGACCTTACTGCCCACCCGGTTTTAATTGGTTATAGCTTTGGGGGCGTGCTTTTATATATGACAATTAACGAAGTTGT
TAAACTTATTAGGTTAAGTT

Downstream 100 bases:

>100_bases
ACTGTTCCACCTCAAGAGTAACTTTGCCCCCACTGGGGACCAACCAGCGGCGATTGCTAAGTTAGCTGAGTTTCAAACCA
ATGAACAGGTCTTACTCGGT

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 808; Mature: 807

Protein sequence:

>808_residues
MGLFNFLKLVSPRHRIYHKASKIANEVEGHKNYYRNLTDVQLLEESNKLVDLVTKQNYTILDVAVAALALIREVVYRETG
EFAYRVQIIGAYIVLIGDFAEMMTGEGKTLTIVLAAYVSALEKRGVHVVTVNEYLAQRDATNATKILKRVGMTVGCNFAN
LAPHLKQAAFACDVTYTTNSELGFDYLRDNMVHRFEDKKIRELHFAIVDEGDSVLIDEARTPLIISGPAKNEFAAYVAVD
RFVKKLKEDEYKIDPESRAPALTELGIKHAEKNFKTDNLFALENSDLFHKIINALTAVKVFEQGKEYIVRDGKVLIVDHF
TGRILEGRSYSNGLHQAVQAKEMVEIEPENVIVATITYQSFFRLYNRLSAVSGTAFTESEEFLKIYNMVVVPVPTNRPNI
RKDRADSVFGTPNIKWLAVVKEVKRIHETGRPILIGTANIDDSELLHNYLQEANIPHEVLNAKNHSREAEIVAKAGQKGA
VTISTNMAGRGTDIRLGEGVAEMGGLYVLGTERNESRRIDNQLRGRAGRQGDRGETKFFISLGDALFKRFAHDRIERAIT
KLGNDTFDSSFFSKMLSRTQKRVEAINFDTRKNLIDYDHVLASQRELIYKQRDKFLLATDLSDMIDKMLEKFVEQFCDQY
RNPKNQNLVNHIALSEALNLELNMHGVISPKLFENMTFDATVHKTHSLIGEKITNKVKVLTPPIALIRFREIMITAMDKH
WIEHLDNVFKLREGVTLRSMEQTSPLNVYIRETDILFQTMLQKIARDVIIQIANLATPEEFDEELMKANALKKLQALREA
HEKSNEGQ

Sequences:

>Translated_808_residues
MGLFNFLKLVSPRHRIYHKASKIANEVEGHKNYYRNLTDVQLLEESNKLVDLVTKQNYTILDVAVAALALIREVVYRETG
EFAYRVQIIGAYIVLIGDFAEMMTGEGKTLTIVLAAYVSALEKRGVHVVTVNEYLAQRDATNATKILKRVGMTVGCNFAN
LAPHLKQAAFACDVTYTTNSELGFDYLRDNMVHRFEDKKIRELHFAIVDEGDSVLIDEARTPLIISGPAKNEFAAYVAVD
RFVKKLKEDEYKIDPESRAPALTELGIKHAEKNFKTDNLFALENSDLFHKIINALTAVKVFEQGKEYIVRDGKVLIVDHF
TGRILEGRSYSNGLHQAVQAKEMVEIEPENVIVATITYQSFFRLYNRLSAVSGTAFTESEEFLKIYNMVVVPVPTNRPNI
RKDRADSVFGTPNIKWLAVVKEVKRIHETGRPILIGTANIDDSELLHNYLQEANIPHEVLNAKNHSREAEIVAKAGQKGA
VTISTNMAGRGTDIRLGEGVAEMGGLYVLGTERNESRRIDNQLRGRAGRQGDRGETKFFISLGDALFKRFAHDRIERAIT
KLGNDTFDSSFFSKMLSRTQKRVEAINFDTRKNLIDYDHVLASQRELIYKQRDKFLLATDLSDMIDKMLEKFVEQFCDQY
RNPKNQNLVNHIALSEALNLELNMHGVISPKLFENMTFDATVHKTHSLIGEKITNKVKVLTPPIALIRFREIMITAMDKH
*IEHLDNVFKLREGVTLRSMEQTSPLNVYIRETDILFQTMLQKIARDVIIQIANLATPEEFDEELMKANALKKLQALREA
HEKSNEGQ
>Mature_807_residues
GLFNFLKLVSPRHRIYHKASKIANEVEGHKNYYRNLTDVQLLEESNKLVDLVTKQNYTILDVAVAALALIREVVYRETGE
FAYRVQIIGAYIVLIGDFAEMMTGEGKTLTIVLAAYVSALEKRGVHVVTVNEYLAQRDATNATKILKRVGMTVGCNFANL
APHLKQAAFACDVTYTTNSELGFDYLRDNMVHRFEDKKIRELHFAIVDEGDSVLIDEARTPLIISGPAKNEFAAYVAVDR
FVKKLKEDEYKIDPESRAPALTELGIKHAEKNFKTDNLFALENSDLFHKIINALTAVKVFEQGKEYIVRDGKVLIVDHFT
GRILEGRSYSNGLHQAVQAKEMVEIEPENVIVATITYQSFFRLYNRLSAVSGTAFTESEEFLKIYNMVVVPVPTNRPNIR
KDRADSVFGTPNIKWLAVVKEVKRIHETGRPILIGTANIDDSELLHNYLQEANIPHEVLNAKNHSREAEIVAKAGQKGAV
TISTNMAGRGTDIRLGEGVAEMGGLYVLGTERNESRRIDNQLRGRAGRQGDRGETKFFISLGDALFKRFAHDRIERAITK
LGNDTFDSSFFSKMLSRTQKRVEAINFDTRKNLIDYDHVLASQRELIYKQRDKFLLATDLSDMIDKMLEKFVEQFCDQYR
NPKNQNLVNHIALSEALNLELNMHGVISPKLFENMTFDATVHKTHSLIGEKITNKVKVLTPPIALIRFREIMITAMDKH*
IEHLDNVFKLREGVTLRSMEQTSPLNVYIRETDILFQTMLQKIARDVIIQIANLATPEEFDEELMKANALKKLQALREAH
EKSNEGQ

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family [H]

Homologues:

Organism=Escherichia coli, GI1786287, Length=803, Percent_Identity=40.3486924034869, Blast_Score=544, Evalue=1e-156,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116 [H]

Pfam domain/function: PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]

EC number: NA

Molecular weight: Translated: 91607; Mature: 91476

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: PS01312 SECA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLFNFLKLVSPRHRIYHKASKIANEVEGHKNYYRNLTDVQLLEESNKLVDLVTKQNYTI
CCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEHHCCCCCH
LDVAVAALALIREVVYRETGEFAYRVQIIGAYIVLIGDFAEMMTGEGKTLTIVLAAYVSA
HHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHH
LEKRGVHVVTVNEYLAQRDATNATKILKRVGMTVGCNFANLAPHLKQAAFACDVTYTTNS
HHHCCCEEEEHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEEEEEEECCC
ELGFDYLRDNMVHRFEDKKIRELHFAIVDEGDSVLIDEARTPLIISGPAKNEFAAYVAVD
CCCHHHHHHHHHHHHCCCHHHHHEEEEECCCCEEEEECCCCCEEEECCCCCHHHHHHHHH
RFVKKLKEDEYKIDPESRAPALTELGIKHAEKNFKTDNLFALENSDLFHKIINALTAVKV
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHH
FEQGKEYIVRDGKVLIVDHFTGRILEGRSYSNGLHQAVQAKEMVEIEPENVIVATITYQS
HHCCCHHEEECCCEEEEECCCCCEECCCCCCHHHHHHHHHHHHHEECCCCEEEEEEEHHH
FFRLYNRLSAVSGTAFTESEEFLKIYNMVVVPVPTNRPNIRKDRADSVFGTPNIKWLAVV
HHHHHHHHHHHCCCCCCCHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHH
KEVKRIHETGRPILIGTANIDDSELLHNYLQEANIPHEVLNAKNHSREAEIVAKAGQKGA
HHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHCCCCCE
VTISTNMAGRGTDIRLGEGVAEMGGLYVLGTERNESRRIDNQLRGRAGRQGDRGETKFFI
EEEEECCCCCCCCEEECCCHHHHCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEE
SLGDALFKRFAHDRIERAITKLGNDTFDSSFFSKMLSRTQKRVEAINFDTRKNLIDYDHV
EHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHH
LASQRELIYKQRDKFLLATDLSDMIDKMLEKFVEQFCDQYRNPKNQNLVNHIALSEALNL
HHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCE
ELNMHGVISPKLFENMTFDATVHKTHSLIGEKITNKVKVLTPPIALIRFREIMITAMDKH
EEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHH
IEHLDNVFKLREGVTLRSMEQTSPLNVYIRETDILFQTMLQKIARDVIIQIANLATPEEF
HHHHHHHHHHHCCCEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
DEELMKANALKKLQALREAHEKSNEGQ
HHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GLFNFLKLVSPRHRIYHKASKIANEVEGHKNYYRNLTDVQLLEESNKLVDLVTKQNYTI
CHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEHHCCCCCH
LDVAVAALALIREVVYRETGEFAYRVQIIGAYIVLIGDFAEMMTGEGKTLTIVLAAYVSA
HHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHH
LEKRGVHVVTVNEYLAQRDATNATKILKRVGMTVGCNFANLAPHLKQAAFACDVTYTTNS
HHHCCCEEEEHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEEEEEEECCC
ELGFDYLRDNMVHRFEDKKIRELHFAIVDEGDSVLIDEARTPLIISGPAKNEFAAYVAVD
CCCHHHHHHHHHHHHCCCHHHHHEEEEECCCCEEEEECCCCCEEEECCCCCHHHHHHHHH
RFVKKLKEDEYKIDPESRAPALTELGIKHAEKNFKTDNLFALENSDLFHKIINALTAVKV
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHH
FEQGKEYIVRDGKVLIVDHFTGRILEGRSYSNGLHQAVQAKEMVEIEPENVIVATITYQS
HHCCCHHEEECCCEEEEECCCCCEECCCCCCHHHHHHHHHHHHHEECCCCEEEEEEEHHH
FFRLYNRLSAVSGTAFTESEEFLKIYNMVVVPVPTNRPNIRKDRADSVFGTPNIKWLAVV
HHHHHHHHHHHCCCCCCCHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHH
KEVKRIHETGRPILIGTANIDDSELLHNYLQEANIPHEVLNAKNHSREAEIVAKAGQKGA
HHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHCCCCCE
VTISTNMAGRGTDIRLGEGVAEMGGLYVLGTERNESRRIDNQLRGRAGRQGDRGETKFFI
EEEEECCCCCCCCEEECCCHHHHCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEE
SLGDALFKRFAHDRIERAITKLGNDTFDSSFFSKMLSRTQKRVEAINFDTRKNLIDYDHV
EHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHH
LASQRELIYKQRDKFLLATDLSDMIDKMLEKFVEQFCDQYRNPKNQNLVNHIALSEALNL
HHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCE
ELNMHGVISPKLFENMTFDATVHKTHSLIGEKITNKVKVLTPPIALIRFREIMITAMDKH
EEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHH
IEHLDNVFKLREGVTLRSMEQTSPLNVYIRETDILFQTMLQKIARDVIIQIANLATPEEF
HHHHHHHHHHHCCCEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
DEELMKANALKKLQALREAHEKSNEGQ
HHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]