Click here to switch to the map view.

The map label for this gene is potA [H]

Identifier: 13507794

GI number: 13507794

Start: 70404

End: 72086

Strand: Direct

Name: potA [H]

Synonym: MPN055

Alternate gene names: 13507794

Gene position: 70404-72086 (Clockwise)

Preceding gene: 13507793

Following gene: 13507795

Centisome position: 8.62

GC content: 38.44

Gene sequence:

>1683_bases
TTGAACGAACGTTTTTTAATTGAAATCGAAGGTTTAAACAAAACTTTCGATGATGGTTTTGTATCAGTACGTGATATTAA
CCTCAAAATTAAGAAGGGCGAATTTATTACGATTCTCGGTCCTTCTGGTTGTGGCAAAACAACTACTCTTAGGTTGTTAG
CAGGTTTTGAAGATCCTACTTATGGCAAGATCAAAGTTAATGGTCTTGACATTAAAGACTTGCCCATTCATAAGCGTCCC
TTTGCTACTGTCTTCCAAGACTATGCCTTGTTTTCACACTTAACTGTGTACAAGAACATTGCTTATGGCTTGAAGGCAAT
GTACACAAAGCTGGATCCGATTGATAAGCTAGTGGAACAATACCACCAAAGCTTACTGGACAAGCAACACCGCTTGCACA
AGAGGATTGAACGCTTAGAAAAAAGTAATGCTAATCCACAACTGTTAGAACAACTTAAACAAACGGTTGTCGTTCAACAA
AAACAGTTTAAACAACAAACAGAGACTTTTAAACAAAAGGAAAATGCTCGACGTGATGCCATTCAACAACGCTTGGTGCA
ACTTACCAAGGAATGGGAAAGCTTATCAAAGCAGAAGTTGCAACAATTAGAAGCGGAGAAAAAGTTGTTAGATAAAAAGT
TTGAACAAACTGAGCGCAAATACCAAAAGGATGCTTGGATGGCAACCCACAGTGAAATGCGTTTAAAGCAGTTCAAACAA
GAGGTGTTAGCTTTAAAACAACTAATTAAAACTAAGTTCAAACAAAATGAACCAGTTGACAAGTTGCAGTTAAAGCTGCA
AACCTTAAAGCAAAAGTATGCTGCTAAAAGACAAATTGATAAGGAATACGATAAGTTGGTCTTAGCCTACAACAAGAAGG
ACTATTGAACTTCATACTGGGAAACCTATTCTTTACAACAACAAGAAGCCTTTGAAAAGCGTTACTTATCGCGCAAACTC
ACTAAACAAGAACAACACCAAAAGGTGTGTGCTGTAATTGAGTTAGTTGGTTTAAAGGGTAACGAGGACAAACTCCCAGA
AGAATTGTCTGGGGGAATGAAGCAACGGGTAGCTTTAGCGCGTTCCTTGGTAATTGAACCAGACATTCTCTTATTGGATG
AACCCTTGTCTGCTTTAGATGCTAAGGTACGTAAAAACTTGCAAAAGGAATTGCAAAAGATTCACCAACAAAGTGGTTTA
ACCTTTATCTTAGTTACTCACGACCAGGAAGAAGCCTTGGTCTTGTCAAACCGCATTGTGGTAATGAATGAGGGTAACAT
TCTCCAAGTTGGTAGTCCGGCTGATATTTACGATTCACCCAAAACCGAGTGGATTGCTAACTTCATTGGTCAAGCTAATA
TCTTTAAGGGTACTTACCTAGGTGACCTTAAGATTAAACTGCACAGCGGTGAAGTGATTAAAACTGATGTGGACAATAAC
TATGTGGTTGGTAAGGAATACAAAATCCTAATTCGTCCCGAAGACTTTGACATTGTGCCCAAAAACAAAGGCTTCTTTAA
TGTTCGGGTAATTGATAAAACCTACAAAGGATTACTCTGAAAGATTACTACTAAGTTAGTTGATGACACCATAGTAGATC
TAGAGAGTGTCAACGACATTGAGGTTGACAAAACCTTTGGGGTCACCTTTGATCCGATTGATGTTCACCTAATGGAGGTA
TAG

Upstream 100 bases:

>100_bases
CATTTTTTTGCAAGAAAATTTATCCCAGTTTTAGGGGGCAAGCGGGGTCAAAAATTGCTACAATAAATACCGTTTTTTCT
TTAAAAATTAAGTAGTTAAA

Downstream 100 bases:

>100_bases
GATGAAACTATCGAAAAAATACCTCTTAGCTGTACCATTCTTTGTTTTAATGGTCATCTTCTTTGTAGTACCAATGGCAT
GGATTATTGTTAGTGGACTC

Product: spermidine/putrescine transport ATP-binding prot

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MNERFLIEIEGLNKTFDDGFVSVRDINLKIKKGEFITILGPSGCGKTTTLRLLAGFEDPTYGKIKVNGLDIKDLPIHKRP
FATVFQDYALFSHLTVYKNIAYGLKAMYTKLDPIDKLVEQYHQSLLDKQHRLHKRIERLEKSNANPQLLEQLKQTVVVQQ
KQFKQQTETFKQKENARRDAIQQRLVQLTKEWESLSKQKLQQLEAEKKLLDKKFEQTERKYQKDAWMATHSEMRLKQFKQ
EVLALKQLIKTKFKQNEPVDKLQLKLQTLKQKYAAKRQIDKEYDKLVLAYNKKDYWTSYWETYSLQQQEAFEKRYLSRKL
TKQEQHQKVCAVIELVGLKGNEDKLPEELSGGMKQRVALARSLVIEPDILLLDEPLSALDAKVRKNLQKELQKIHQQSGL
TFILVTHDQEEALVLSNRIVVMNEGNILQVGSPADIYDSPKTEWIANFIGQANIFKGTYLGDLKIKLHSGEVIKTDVDNN
YVVGKEYKILIRPEDFDIVPKNKGFFNVRVIDKTYKGLLWKITTKLVDDTIVDLESVNDIEVDKTFGVTFDPIDVHLMEV

Sequences:

>Translated_560_residues
MNERFLIEIEGLNKTFDDGFVSVRDINLKIKKGEFITILGPSGCGKTTTLRLLAGFEDPTYGKIKVNGLDIKDLPIHKRP
FATVFQDYALFSHLTVYKNIAYGLKAMYTKLDPIDKLVEQYHQSLLDKQHRLHKRIERLEKSNANPQLLEQLKQTVVVQQ
KQFKQQTETFKQKENARRDAIQQRLVQLTKEWESLSKQKLQQLEAEKKLLDKKFEQTERKYQKDAWMATHSEMRLKQFKQ
EVLALKQLIKTKFKQNEPVDKLQLKLQTLKQKYAAKRQIDKEYDKLVLAYNKKDY*TSYWETYSLQQQEAFEKRYLSRKL
TKQEQHQKVCAVIELVGLKGNEDKLPEELSGGMKQRVALARSLVIEPDILLLDEPLSALDAKVRKNLQKELQKIHQQSGL
TFILVTHDQEEALVLSNRIVVMNEGNILQVGSPADIYDSPKTEWIANFIGQANIFKGTYLGDLKIKLHSGEVIKTDVDNN
YVVGKEYKILIRPEDFDIVPKNKGFFNVRVIDKTYKGLL*KITTKLVDDTIVDLESVNDIEVDKTFGVTFDPIDVHLMEV
>Mature_560_residues
MNERFLIEIEGLNKTFDDGFVSVRDINLKIKKGEFITILGPSGCGKTTTLRLLAGFEDPTYGKIKVNGLDIKDLPIHKRP
FATVFQDYALFSHLTVYKNIAYGLKAMYTKLDPIDKLVEQYHQSLLDKQHRLHKRIERLEKSNANPQLLEQLKQTVVVQQ
KQFKQQTETFKQKENARRDAIQQRLVQLTKEWESLSKQKLQQLEAEKKLLDKKFEQTERKYQKDAWMATHSEMRLKQFKQ
EVLALKQLIKTKFKQNEPVDKLQLKLQTLKQKYAAKRQIDKEYDKLVLAYNKKDY*TSYWETYSLQQQEAFEKRYLSRKL
TKQEQHQKVCAVIELVGLKGNEDKLPEELSGGMKQRVALARSLVIEPDILLLDEPLSALDAKVRKNLQKELQKIHQQSGL
TFILVTHDQEEALVLSNRIVVMNEGNILQVGSPADIYDSPKTEWIANFIGQANIFKGTYLGDLKIKLHSGEVIKTDVDNN
YVVGKEYKILIRPEDFDIVPKNKGFFNVRVIDKTYKGLL*KITTKLVDDTIVDLESVNDIEVDKTFGVTFDPIDVHLMEV

Specific function: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system [H]

COG id: COG3842

COG function: function code E; ABC-type spermidine/putrescine transport systems, ATPase components

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI116734710, Length=115, Percent_Identity=32.1739130434783, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI30795238, Length=113, Percent_Identity=32.7433628318584, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI27881501, Length=113, Percent_Identity=32.7433628318584, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1787370, Length=284, Percent_Identity=34.1549295774648, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1787712, Length=142, Percent_Identity=48.5915492957746, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI87081791, Length=216, Percent_Identity=39.3518518518519, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1788761, Length=193, Percent_Identity=39.3782383419689, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI87081709, Length=140, Percent_Identity=42.1428571428571, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI87082267, Length=192, Percent_Identity=35.9375, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1790467, Length=285, Percent_Identity=30.8771929824561, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1789032, Length=156, Percent_Identity=36.5384615384615, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788450, Length=124, Percent_Identity=40.3225806451613, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1789672, Length=134, Percent_Identity=35.8208955223881, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787164, Length=92, Percent_Identity=48.9130434782609, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1787500, Length=128, Percent_Identity=34.375, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1786872, Length=131, Percent_Identity=35.8778625954198, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789962, Length=134, Percent_Identity=30.5970149253731, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786398, Length=128, Percent_Identity=35.15625, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788506, Length=126, Percent_Identity=30.952380952381, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786253, Length=79, Percent_Identity=46.8354430379747, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787029, Length=132, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1786563, Length=90, Percent_Identity=45.5555555555556, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1788644, Length=131, Percent_Identity=32.824427480916, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787089, Length=145, Percent_Identity=33.1034482758621, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787758, Length=98, Percent_Identity=37.7551020408163, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788225, Length=128, Percent_Identity=32.03125, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787547, Length=142, Percent_Identity=29.5774647887324, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI145693107, Length=126, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789963, Length=146, Percent_Identity=28.0821917808219, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI48994997, Length=98, Percent_Identity=36.734693877551, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789891, Length=111, Percent_Identity=37.8378378378378, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789864, Length=136, Percent_Identity=29.4117647058824, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87081782, Length=148, Percent_Identity=32.4324324324324, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790190, Length=151, Percent_Identity=32.4503311258278, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI48994883, Length=150, Percent_Identity=25.3333333333333, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787759, Length=107, Percent_Identity=30.8411214953271, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786703, Length=113, Percent_Identity=36.283185840708, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790544, Length=110, Percent_Identity=32.7272727272727, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786345, Length=119, Percent_Identity=36.1344537815126, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789873, Length=130, Percent_Identity=32.3076923076923, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790162, Length=150, Percent_Identity=29.3333333333333, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789890, Length=132, Percent_Identity=31.0606060606061, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1786319, Length=92, Percent_Identity=36.9565217391304, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87081834, Length=104, Percent_Identity=36.5384615384615, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI48994943, Length=150, Percent_Identity=28, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789586, Length=107, Percent_Identity=35.5140186915888, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786803, Length=115, Percent_Identity=30.4347826086957, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1789593, Length=94, Percent_Identity=29.7872340425532, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI193211017, Length=117, Percent_Identity=39.3162393162393, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71983516, Length=105, Percent_Identity=29.5238095238095, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71983510, Length=105, Percent_Identity=29.5238095238095, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71983523, Length=105, Percent_Identity=29.5238095238095, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193211015, Length=117, Percent_Identity=39.3162393162393, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71996809, Length=117, Percent_Identity=39.3162393162393, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI25146777, Length=113, Percent_Identity=39.8230088495575, Blast_Score=69, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI193202349, Length=85, Percent_Identity=45.8823529411765, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI212646699, Length=95, Percent_Identity=44.2105263157895, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323217, Length=117, Percent_Identity=35.8974358974359, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI85726357, Length=98, Percent_Identity=41.8367346938776, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007184, Length=106, Percent_Identity=30.188679245283, Blast_Score=66, Evalue=8e-11,
Organism=Drosophila melanogaster, GI221500365, Length=106, Percent_Identity=30.188679245283, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR008995
- InterPro:   IPR017879 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.31 [H]

Molecular weight: Translated: 64724; Mature: 64724

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNERFLIEIEGLNKTFDDGFVSVRDINLKIKKGEFITILGPSGCGKTTTLRLLAGFEDPT
CCCEEEEEEECCCCCCCCCCEEEEEEEEEEECCCEEEEECCCCCCCCCEEEEEECCCCCC
YGKIKVNGLDIKDLPIHKRPFATVFQDYALFSHLTVYKNIAYGLKAMYTKLDPIDKLVEQ
CCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
YHQSLLDKQHRLHKRIERLEKSNANPQLLEQLKQTVVVQQKQFKQQTETFKQKENARRDA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQQRLVQLTKEWESLSKQKLQQLEAEKKLLDKKFEQTERKYQKDAWMATHSEMRLKQFKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVLALKQLIKTKFKQNEPVDKLQLKLQTLKQKYAAKRQIDKEYDKLVLAYNKKDYTSYWE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHH
TYSLQQQEAFEKRYLSRKLTKQEQHQKVCAVIELVGLKGNEDKLPEELSGGMKQRVALAR
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCHHHHHHHHHH
SLVIEPDILLLDEPLSALDAKVRKNLQKELQKIHQQSGLTFILVTHDQEEALVLSNRIVV
HHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECEEEE
MNEGNILQVGSPADIYDSPKTEWIANFIGQANIFKGTYLGDLKIKLHSGEVIKTDVDNNY
EECCCEEEECCCCCCCCCCHHHHHHHHHCCCCEECCEEEEEEEEEEECCCEEEEECCCCE
VVGKEYKILIRPEDFDIVPKNKGFFNVRVIDKTYKGLLKITTKLVDDTIVDLESVNDIEV
EECCCEEEEECCCCCEECCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
DKTFGVTFDPIDVHLMEV
CCCCCCEECCCCEEEEEC
>Mature Secondary Structure
MNERFLIEIEGLNKTFDDGFVSVRDINLKIKKGEFITILGPSGCGKTTTLRLLAGFEDPT
CCCEEEEEEECCCCCCCCCCEEEEEEEEEEECCCEEEEECCCCCCCCCEEEEEECCCCCC
YGKIKVNGLDIKDLPIHKRPFATVFQDYALFSHLTVYKNIAYGLKAMYTKLDPIDKLVEQ
CCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
YHQSLLDKQHRLHKRIERLEKSNANPQLLEQLKQTVVVQQKQFKQQTETFKQKENARRDA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQQRLVQLTKEWESLSKQKLQQLEAEKKLLDKKFEQTERKYQKDAWMATHSEMRLKQFKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVLALKQLIKTKFKQNEPVDKLQLKLQTLKQKYAAKRQIDKEYDKLVLAYNKKDYTSYWE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHH
TYSLQQQEAFEKRYLSRKLTKQEQHQKVCAVIELVGLKGNEDKLPEELSGGMKQRVALAR
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCHHHHHHHHHH
SLVIEPDILLLDEPLSALDAKVRKNLQKELQKIHQQSGLTFILVTHDQEEALVLSNRIVV
HHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECEEEE
MNEGNILQVGSPADIYDSPKTEWIANFIGQANIFKGTYLGDLKIKLHSGEVIKTDVDNNY
EECCCEEEECCCCCCCCCCHHHHHHHHHCCCCEECCEEEEEEEEEEECCCEEEEECCCCE
VVGKEYKILIRPEDFDIVPKNKGFFNVRVIDKTYKGLLKITTKLVDDTIVDLESVNDIEV
EECCCEEEEECCCCCEECCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
DKTFGVTFDPIDVHLMEV
CCCCCCEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]