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The map label for this gene is rpoE [H]

Identifier: 13507763

GI number: 13507763

Start: 29804

End: 30244

Strand: Direct

Name: rpoE [H]

Synonym: MPN024

Alternate gene names: 13507763

Gene position: 29804-30244 (Clockwise)

Preceding gene: 13507762

Following gene: 13507764

Centisome position: 3.65

GC content: 40.59

Gene sequence:

>441_bases
ATGACTATGCAAGTAGAATACCTCGATCTCATCTCCCAAGCGAAGGAGATTGCTGAGACCCAATTTAAGGCGGAACCGTT
TTCCTTTGATGCTATTTGAAAGGAAGTAGTGAAGCACTTTAAGATCTCCAAACAAGACGAACCTAACCTAATTTCGCGGT
TTTACCAAGACTTTTTGGAAGACCCTAACTTTGTTTATTTAGGGGAACGCAACTGGAAGTTAAGGGACTTCATGAAGTTT
GATGAATGGAACAAGATTTCCCAAGCAATGTTTGTGACCAAGGAAATCTTTGAAGAGGGTTATGAAGACCTGTCCAACAA
GAAGAAGGAAAACGAGGAAGAAGTGAATGACTTCATTATGGGCAATGATGGTGATGACAACAGTACCGGTGATGAAATTG
TGCAAGGACTCATTAACGATTTTCGCGACGATAACCAATAA

Upstream 100 bases:

>100_bases
CCCACCTAGCTGATCCACAACAACTGCAAAAAATCAGCTTAGCACCTGTAATTCAACCTTTATTTAAAAGATTGGATTAA
TTAAATTAGATTAGAATTTA

Downstream 100 bases:

>100_bases
TGCTAGTAAACATCAAACAAATGTTGCAACACGCTAAGCAACACCACTATGCTGTACCCCACATTAATATCAATAACTAT
GAATGGGCTAAGGCAGTATT

Product: DNA-directed RNA polymerase subunit delta

Products: diphosphate; RNAn+1

Alternate protein names: RNAP delta factor [H]

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MTMQVEYLDLISQAKEIAETQFKAEPFSFDAIWKEVVKHFKISKQDEPNLISRFYQDFLEDPNFVYLGERNWKLRDFMKF
DEWNKISQAMFVTKEIFEEGYEDLSNKKKENEEEVNDFIMGNDGDDNSTGDEIVQGLINDFRDDNQ

Sequences:

>Translated_146_residues
MTMQVEYLDLISQAKEIAETQFKAEPFSFDAI*KEVVKHFKISKQDEPNLISRFYQDFLEDPNFVYLGERNWKLRDFMKF
DEWNKISQAMFVTKEIFEEGYEDLSNKKKENEEEVNDFIMGNDGDDNSTGDEIVQGLINDFRDDNQ
>Mature_145_residues
TMQVEYLDLISQAKEIAETQFKAEPFSFDAI*KEVVKHFKISKQDEPNLISRFYQDFLEDPNFVYLGERNWKLRDFMKFD
EWNKISQAMFVTKEIFEEGYEDLSNKKKENEEEVNDFIMGNDGDDNSTGDEIVQGLINDFRDDNQ

Specific function: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis

COG id: COG3343

COG function: function code K; DNA-directed RNA polymerase, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rpoE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007759 [H]

Pfam domain/function: PF05066 RNA_pol_delta [H]

EC number: 2.7.7.6

Molecular weight: Translated: 17202; Mature: 17071

Theoretical pI: Translated: 4.07; Mature: 4.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMQVEYLDLISQAKEIAETQFKAEPFSFDAIKEVVKHFKISKQDEPNLISRFYQDFLED
CCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
PNFVYLGERNWKLRDFMKFDEWNKISQAMFVTKEIFEEGYEDLSNKKKENEEEVNDFIMG
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
NDGDDNSTGDEIVQGLINDFRDDNQ
CCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TMQVEYLDLISQAKEIAETQFKAEPFSFDAIKEVVKHFKISKQDEPNLISRFYQDFLED
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
PNFVYLGERNWKLRDFMKFDEWNKISQAMFVTKEIFEEGYEDLSNKKKENEEEVNDFIMG
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
NDGDDNSTGDEIVQGLINDFRDDNQ
CCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nucleoside triphosphate; RNAn

Specific reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]