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The map label for this gene is dgoD [H]

Identifier: 13488170

GI number: 13488170

Start: 328245

End: 329393

Strand: Reverse

Name: dgoD [H]

Synonym: mll9372

Alternate gene names: 13488170

Gene position: 329393-328245 (Counterclockwise)

Preceding gene: 13488171

Following gene: 13488169

Centisome position: 93.6

GC content: 52.31

Gene sequence:

>1149_bases
ATGAAAATTACTGGTGTAAATATCTATTTGCTCAAATCTGGCCGCCTCCATCCTGTCTTGGTTGAAATCTCGACGGACGA
AGGCATAACGGGGGCTGGCGAGGCGGGAATAGCCTATGGCGTTGGCGGGACCGCAGCGGCAGGGATGATCAAGGATCTCT
CGGAAAGATTCTTAATCGGCAAAGACCCATCTCGGATCGAAGAGCTGTGGTCAACAATGTATGATCATTCATTTTGGGCA
AAGAATGGTGGTGCGATTATCTTTGCCGGCATCAGCGCGATAGAGCAGGCTCTGTGGGACATCAAAGGCAAATGTCTCGG
GGTCCCCGTTTATGAGCTTTTCGGCGGAAAAATCCGGGACCGTGTGCGCGCCTACGCGAACGGTTGGTACGGTGCGGCTG
ACACGCCGGACGAATTTGCCCGGGCGGTAGAACGCCCTCTGAAGGAGGGGTATGGGGCGCTCAAATTCTACCCTTTGGCA
CAGCGGGTCGGCTCGGCTTTACAGCACGTGACACGACGATCGATGTCCGCCGAAGCAATTGAGCTTGCATACCGCCGGGT
CAAGGCTGTCCGTGATGCGGCCGGGCCCGAAATTGAGCTCATGGTCGATCTCAGTGGGGGCTTGACTACCGATGAGACGA
TTCGGTTTTGCCGAAAAATCGGTGAGCTCGATATTTGCTTTGTAGAAGAGCCATGCGATCCATTCGACAACGGGGCGCTG
AAAGTAATTTCGGAACAAATTCCCTTGCCGATAGCGGTTGGAGAACGTGTCTATACCAGATTTGGGTTCCGTAAGATCTT
CGAGTTGCAGGCTTGCGGGATTATCCAGCCTGATATTGGAACGGCGGGAGGCTTGATGGAGACGAAGAAGATTTGCGCAA
TGGCAGAAGCATACAATATGCGTGTAGCTCCACATGTGTGCGGAAGCAGCCTAATTGAAACTGCAACGCTCCAGCTTGAG
GCTAATATCACGAATTTTATGATCCACGAGCATTATCCTGCTTTTAAGGCGGATGACGGATATGTTGAGGTTCTTGAGAA
TCCGCCGTCGATCAGTTCTGGATACTTTGAAATGCCCAACGGGCCCGGACTTGGAGCAGTTCTTATAAAACGAAACATCG
AACCGTACCTCTGGGCTTCATGCACATAG

Upstream 100 bases:

>100_bases
TGCCGGAACAGAACCTTGTTTCTGGTTCGAGGAATGCCCTCAGCGACCGAGTATCAGCGCATCAGCCTTTAAGCTCACAC
CATCGGATTGCGAGGCGACT

Downstream 100 bases:

>100_bases
GCATCCACTACCGATAGACTTCCGCGAGTACGGCTTTCGAGATGCGACCCGTGGCCTCATCGATGAGGACTGTCGAGGAG
GCCCAATCGCTCACCTGGGG

Product: putative dehydratase

Products: NA

Alternate protein names: GalD [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MKITGVNIYLLKSGRLHPVLVEISTDEGITGAGEAGIAYGVGGTAAAGMIKDLSERFLIGKDPSRIEELWSTMYDHSFWA
KNGGAIIFAGISAIEQALWDIKGKCLGVPVYELFGGKIRDRVRAYANGWYGAADTPDEFARAVERPLKEGYGALKFYPLA
QRVGSALQHVTRRSMSAEAIELAYRRVKAVRDAAGPEIELMVDLSGGLTTDETIRFCRKIGELDICFVEEPCDPFDNGAL
KVISEQIPLPIAVGERVYTRFGFRKIFELQACGIIQPDIGTAGGLMETKKICAMAEAYNMRVAPHVCGSSLIETATLQLE
ANITNFMIHEHYPAFKADDGYVEVLENPPSISSGYFEMPNGPGLGAVLIKRNIEPYLWASCT

Sequences:

>Translated_382_residues
MKITGVNIYLLKSGRLHPVLVEISTDEGITGAGEAGIAYGVGGTAAAGMIKDLSERFLIGKDPSRIEELWSTMYDHSFWA
KNGGAIIFAGISAIEQALWDIKGKCLGVPVYELFGGKIRDRVRAYANGWYGAADTPDEFARAVERPLKEGYGALKFYPLA
QRVGSALQHVTRRSMSAEAIELAYRRVKAVRDAAGPEIELMVDLSGGLTTDETIRFCRKIGELDICFVEEPCDPFDNGAL
KVISEQIPLPIAVGERVYTRFGFRKIFELQACGIIQPDIGTAGGLMETKKICAMAEAYNMRVAPHVCGSSLIETATLQLE
ANITNFMIHEHYPAFKADDGYVEVLENPPSISSGYFEMPNGPGLGAVLIKRNIEPYLWASCT
>Mature_382_residues
MKITGVNIYLLKSGRLHPVLVEISTDEGITGAGEAGIAYGVGGTAAAGMIKDLSERFLIGKDPSRIEELWSTMYDHSFWA
KNGGAIIFAGISAIEQALWDIKGKCLGVPVYELFGGKIRDRVRAYANGWYGAADTPDEFARAVERPLKEGYGALKFYPLA
QRVGSALQHVTRRSMSAEAIELAYRRVKAVRDAAGPEIELMVDLSGGLTTDETIRFCRKIGELDICFVEEPCDPFDNGAL
KVISEQIPLPIAVGERVYTRFGFRKIFELQACGIIQPDIGTAGGLMETKKICAMAEAYNMRVAPHVCGSSLIETATLQLE
ANITNFMIHEHYPAFKADDGYVEVLENPPSISSGYFEMPNGPGLGAVLIKRNIEPYLWASCT

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Homo sapiens, GI42544119, Length=422, Percent_Identity=21.563981042654, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI186972148, Length=348, Percent_Identity=21.8390804597701, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI48994953, Length=371, Percent_Identity=32.3450134770889, Blast_Score=177, Evalue=7e-46,
Organism=Escherichia coli, GI1787864, Length=381, Percent_Identity=27.5590551181102, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI226510960, Length=281, Percent_Identity=26.3345195729537, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 41715; Mature: 41715

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITGVNIYLLKSGRLHPVLVEISTDEGITGAGEAGIAYGVGGTAAAGMIKDLSERFLIG
CEEEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHEECC
KDPSRIEELWSTMYDHSFWAKNGGAIIFAGISAIEQALWDIKGKCLGVPVYELFGGKIRD
CCHHHHHHHHHHHHCCCCEECCCCEEEEECHHHHHHHHHHCCCCEECCCHHHHHCCHHHH
RVRAYANGWYGAADTPDEFARAVERPLKEGYGALKFYPLAQRVGSALQHVTRRSMSAEAI
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHH
ELAYRRVKAVRDAAGPEIELMVDLSGGLTTDETIRFCRKIGELDICFVEEPCDPFDNGAL
HHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCHH
KVISEQIPLPIAVGERVYTRFGFRKIFELQACGIIQPDIGTAGGLMETKKICAMAEAYNM
HHHHHCCCCCEECCHHHHHHHHHHHHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHHHCC
RVAPHVCGSSLIETATLQLEANITNFMIHEHYPAFKADDGYVEVLENPPSISSGYFEMPN
EECHHHHHHHHHHEEEEEEEECCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCEEECCC
GPGLGAVLIKRNIEPYLWASCT
CCCCEEEEEECCCCCCEEECCC
>Mature Secondary Structure
MKITGVNIYLLKSGRLHPVLVEISTDEGITGAGEAGIAYGVGGTAAAGMIKDLSERFLIG
CEEEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHEECC
KDPSRIEELWSTMYDHSFWAKNGGAIIFAGISAIEQALWDIKGKCLGVPVYELFGGKIRD
CCHHHHHHHHHHHHCCCCEECCCCEEEEECHHHHHHHHHHCCCCEECCCHHHHHCCHHHH
RVRAYANGWYGAADTPDEFARAVERPLKEGYGALKFYPLAQRVGSALQHVTRRSMSAEAI
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHH
ELAYRRVKAVRDAAGPEIELMVDLSGGLTTDETIRFCRKIGELDICFVEEPCDPFDNGAL
HHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCHH
KVISEQIPLPIAVGERVYTRFGFRKIFELQACGIIQPDIGTAGGLMETKKICAMAEAYNM
HHHHHCCCCCEECCHHHHHHHHHHHHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHHHCC
RVAPHVCGSSLIETATLQLEANITNFMIHEHYPAFKADDGYVEVLENPPSISSGYFEMPN
EECHHHHHHHHHHEEEEEEEECCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCEEECCC
GPGLGAVLIKRNIEPYLWASCT
CCCCEEEEEECCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA