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The map label for this gene is bioD [H]

Identifier: 13488067

GI number: 13488067

Start: 77437

End: 78072

Strand: Reverse

Name: bioD [H]

Synonym: mll9098

Alternate gene names: 13488067

Gene position: 78072-77437 (Counterclockwise)

Preceding gene: 13488068

Following gene: 13488066

Centisome position: 22.19

GC content: 61.48

Gene sequence:

>636_bases
ATGACCAAGCGCGTTGTCGTCGCCGGAACCGATACCGGCATCGGCAAAACGGTGTTTTCGGCGGGATTGGCCGGCCTGCT
CGACGGCTTCTACTGGAAGCCGGTGCAATCGGGCCTCGACGAGGAAACCGACAGCGAGGTCGTTGCCCGGCTTTCCGGCT
TGCCCGCCGGGCGCGTGCTGCCGGAAGCCTACCGCTTGCAGAGCCCGCTTTCGCCGCATCGTTCGGCCGAGATCGACGGT
GTTGCGATCAAAGCTGCCGATCTTTCTTTTCCCCTCCTGCCAACACCACTCGTCATCGAAGGCGCGGGCGGCCTGATGGT
GCCGCTCAATCGAAAGACAAGGTTCATCGACATCTTCGCTGAGTGGCAGCTGCCGGTCATTCTGTGCGCCCGCACCACCC
TCGGCACAATCAACCACACCCTGCTGTCGATCGAGGCCCTGCGCGCTCGCTCCATCCCCCTGGCAGGAATCGCTTTCATC
GGTGATGAGATGGTCGATACGCAACGGACAATCGTGGAAATGGGTGGGGTACCGCAGCTTGGCAGGTTGCCCTATCTCGA
TCCGCTGACGGACAAAACGTTAAGAGCGGCAATGATTGCCGGATTTGCCTTCGCCTCGTGTCCGGGAGATCACTGA

Upstream 100 bases:

>100_bases
GCCTGCGCATCTCGCTGACGCTCAACGTCGACGAAGCCGCCATTTCGGCCATGATCGAGGCGCTCGTCGAAGTGTTGGCC
CAAACATGACCGGAGGCGAC

Downstream 100 bases:

>100_bases
TGTCCCCCGTCTGGCATCCCTTCACCCAGCACGCGCTCGAGCTCGCCATCCCTGAAATCGCCCGGACGGAAGGCGCCTAC
CTCCACAAGGCCGACGGCAC

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MTKRVVVAGTDTGIGKTVFSAGLAGLLDGFYWKPVQSGLDEETDSEVVARLSGLPAGRVLPEAYRLQSPLSPHRSAEIDG
VAIKAADLSFPLLPTPLVIEGAGGLMVPLNRKTRFIDIFAEWQLPVILCARTTLGTINHTLLSIEALRARSIPLAGIAFI
GDEMVDTQRTIVEMGGVPQLGRLPYLDPLTDKTLRAAMIAGFAFASCPGDH

Sequences:

>Translated_211_residues
MTKRVVVAGTDTGIGKTVFSAGLAGLLDGFYWKPVQSGLDEETDSEVVARLSGLPAGRVLPEAYRLQSPLSPHRSAEIDG
VAIKAADLSFPLLPTPLVIEGAGGLMVPLNRKTRFIDIFAEWQLPVILCARTTLGTINHTLLSIEALRARSIPLAGIAFI
GDEMVDTQRTIVEMGGVPQLGRLPYLDPLTDKTLRAAMIAGFAFASCPGDH
>Mature_210_residues
TKRVVVAGTDTGIGKTVFSAGLAGLLDGFYWKPVQSGLDEETDSEVVARLSGLPAGRVLPEAYRLQSPLSPHRSAEIDGV
AIKAADLSFPLLPTPLVIEGAGGLMVPLNRKTRFIDIFAEWQLPVILCARTTLGTINHTLLSIEALRARSIPLAGIAFIG
DEMVDTQRTIVEMGGVPQLGRLPYLDPLTDKTLRAAMIAGFAFASCPGDH

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=208, Percent_Identity=32.2115384615385, Blast_Score=84, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6324385, Length=159, Percent_Identity=38.9937106918239, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472 [H]

Pfam domain/function: NA

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 22491; Mature: 22360

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRVVVAGTDTGIGKTVFSAGLAGLLDGFYWKPVQSGLDEETDSEVVARLSGLPAGRVL
CCCEEEEEECCCCCHHHHHHHHHHHHHHCHHHCHHHHCCCCCCHHHHHHHHHCCCCCCCC
PEAYRLQSPLSPHRSAEIDGVAIKAADLSFPLLPTPLVIEGAGGLMVPLNRKTRFIDIFA
HHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCEEEEECCCEEEEEEEE
EWQLPVILCARTTLGTINHTLLSIEALRARSIPLAGIAFIGDEMVDTQRTIVEMGGVPQL
CCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCEEHHHHHCHHHHHHHHHHHHHCCCCCC
GRLPYLDPLTDKTLRAAMIAGFAFASCPGDH
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TKRVVVAGTDTGIGKTVFSAGLAGLLDGFYWKPVQSGLDEETDSEVVARLSGLPAGRVL
CCEEEEEECCCCCHHHHHHHHHHHHHHCHHHCHHHHCCCCCCHHHHHHHHHCCCCCCCC
PEAYRLQSPLSPHRSAEIDGVAIKAADLSFPLLPTPLVIEGAGGLMVPLNRKTRFIDIFA
HHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCEEEEECCCEEEEEEEE
EWQLPVILCARTTLGTINHTLLSIEALRARSIPLAGIAFIGDEMVDTQRTIVEMGGVPQL
CCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCEEHHHHHCHHHHHHHHHHHHHCCCCCC
GRLPYLDPLTDKTLRAAMIAGFAFASCPGDH
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA