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The map label for this gene is fabH [H]

Identifier: 13488065

GI number: 13488065

Start: 75198

End: 76181

Strand: Reverse

Name: fabH [H]

Synonym: mll9094

Alternate gene names: 13488065

Gene position: 76181-75198 (Counterclockwise)

Preceding gene: 13488066

Following gene: 13488064

Centisome position: 21.65

GC content: 64.43

Gene sequence:

>984_bases
ATGAGCAAGTCGTCGCGCATTCTCGGGTTCGGCCATCATGCGCCCGGGCGCAAAGTGGAGAATGCCGAGATCGAGAACAA
TCTCGGCCTCGAGCCGGGCTGGATCGAGCGGCGTACCGGAATTCGTTCGCGCTTCTGGGCAACGGACGAAGACACGCTGT
CGGGCCTTGCCGCGCAAGCCGGCGACATGGCGCTGGCGAACGCCGGTATTGACCAAAGCGACATCGGTCTGCTGTTGCTT
GCCACCTCGACACCCGACCACCTTCTGCCGCCCAGTGCACCCCTGGTCGCGCACAATCTCGGCGTTGGTCGCGCAGGGGC
GGTCGATCTGACCGCCGCCTGCGCTGGCTTCATCTATGCGCTGATGTTTGCCGACGGGTTCACCCGCCTGCACGGCAAAC
CAGCGTTGGTCATTGCCGCCAACATCCTCAGCCGCCGCATCAACCCGGCCGAGCGAGCCAGCGCGGTTCTGTTTGCCGAC
GCTGCCGGCGCCCTGGTGATTGGTCCTTGCGAGGATCCCGAGCGGGGCATCCTCGGCGCATCGGTGGATTCCGACGGCTC
GCGCTACGGGCTTATCCAGATACCCGCTGGAGGAAGCAACACGCCGTTTCATAGCGACCTCGACCTCGCGCAGACCAGGA
TGACGATCACTGACGGCCGCGAAGTGTTCAGCAAGGCTGTTGAGATGATGACCGCCTGCTCGCAGGACGCGCTCGCCGCA
GCGCGAATGCGGCCGCAAGACATCGATCGGTTCGTGCCGCATCAGGCGAATAGCCGCATTTTCGATGCGGTCGGCAGGAG
CCTGGGCATAGCGGATCAGGCAATCGTCAAGACGATCGCCAACTATGGCAACTCTTCCGCCGCGACGATCCCGCTGTCGC
TCTCGCTGGCCAACCAGACGGAACCGTTCCGGTCTGGCGAGAAGATTCTTCTGGCAGCCGCGGGTGCCGGTCTCAGCGGC
GGCGCTCTCGTCGTCGGAATCTAG

Upstream 100 bases:

>100_bases
ACGTGCTCGATCTCATGCCGCCCTATTGCATCACCGGCGACGAACTCGACGGACTCTATGACGCCATCGAGGAGGCCGCC
GAACGCTTCGGGTCTAGGCC

Downstream 100 bases:

>100_bases
CGGGGGCGACCCGCTGCCAAGATTAACCTTGCATGATGAATAGGGACAACAAAACCAATGCGCAAAATAGTCGCCGGCAA
GCTGCACGGCATCCACGTCA

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MSKSSRILGFGHHAPGRKVENAEIENNLGLEPGWIERRTGIRSRFWATDEDTLSGLAAQAGDMALANAGIDQSDIGLLLL
ATSTPDHLLPPSAPLVAHNLGVGRAGAVDLTAACAGFIYALMFADGFTRLHGKPALVIAANILSRRINPAERASAVLFAD
AAGALVIGPCEDPERGILGASVDSDGSRYGLIQIPAGGSNTPFHSDLDLAQTRMTITDGREVFSKAVEMMTACSQDALAA
ARMRPQDIDRFVPHQANSRIFDAVGRSLGIADQAIVKTIANYGNSSAATIPLSLSLANQTEPFRSGEKILLAAAGAGLSG
GALVVGI

Sequences:

>Translated_327_residues
MSKSSRILGFGHHAPGRKVENAEIENNLGLEPGWIERRTGIRSRFWATDEDTLSGLAAQAGDMALANAGIDQSDIGLLLL
ATSTPDHLLPPSAPLVAHNLGVGRAGAVDLTAACAGFIYALMFADGFTRLHGKPALVIAANILSRRINPAERASAVLFAD
AAGALVIGPCEDPERGILGASVDSDGSRYGLIQIPAGGSNTPFHSDLDLAQTRMTITDGREVFSKAVEMMTACSQDALAA
ARMRPQDIDRFVPHQANSRIFDAVGRSLGIADQAIVKTIANYGNSSAATIPLSLSLANQTEPFRSGEKILLAAAGAGLSG
GALVVGI
>Mature_326_residues
SKSSRILGFGHHAPGRKVENAEIENNLGLEPGWIERRTGIRSRFWATDEDTLSGLAAQAGDMALANAGIDQSDIGLLLLA
TSTPDHLLPPSAPLVAHNLGVGRAGAVDLTAACAGFIYALMFADGFTRLHGKPALVIAANILSRRINPAERASAVLFADA
AGALVIGPCEDPERGILGASVDSDGSRYGLIQIPAGGSNTPFHSDLDLAQTRMTITDGREVFSKAVEMMTACSQDALAAA
RMRPQDIDRFVPHQANSRIFDAVGRSLGIADQAIVKTIANYGNSSAATIPLSLSLANQTEPFRSGEKILLAAAGAGLSGG
ALVVGI

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=322, Percent_Identity=34.472049689441, Blast_Score=186, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 33988; Mature: 33857

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSSRILGFGHHAPGRKVENAEIENNLGLEPGWIERRTGIRSRFWATDEDTLSGLAAQA
CCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHCCCCCHHHHHHHHHHC
GDMALANAGIDQSDIGLLLLATSTPDHLLPPSAPLVAHNLGVGRAGAVDLTAACAGFIYA
CCEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHH
LMFADGFTRLHGKPALVIAANILSRRINPAERASAVLFADAAGALVIGPCEDPERGILGA
HHHHCCHHHHCCCCEEEEEEHHHHHCCCHHHHHCEEEEECCCCEEEEECCCCCCCCEEEC
SVDSDGSRYGLIQIPAGGSNTPFHSDLDLAQTRMTITDGREVFSKAVEMMTACSQDALAA
CCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHEEEECCCHHHHHHHHHHHHHCCHHHHHH
ARMRPQDIDRFVPHQANSRIFDAVGRSLGIADQAIVKTIANYGNSSAATIPLSLSLANQT
HHCCHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCC
EPFRSGEKILLAAAGAGLSGGALVVGI
CCCCCCCEEEEEEECCCCCCCEEEEEC
>Mature Secondary Structure 
SKSSRILGFGHHAPGRKVENAEIENNLGLEPGWIERRTGIRSRFWATDEDTLSGLAAQA
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHCCCCCHHHHHHHHHHC
GDMALANAGIDQSDIGLLLLATSTPDHLLPPSAPLVAHNLGVGRAGAVDLTAACAGFIYA
CCEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHH
LMFADGFTRLHGKPALVIAANILSRRINPAERASAVLFADAAGALVIGPCEDPERGILGA
HHHHCCHHHHCCCCEEEEEEHHHHHCCCHHHHHCEEEEECCCCEEEEECCCCCCCCEEEC
SVDSDGSRYGLIQIPAGGSNTPFHSDLDLAQTRMTITDGREVFSKAVEMMTACSQDALAA
CCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHEEEECCCHHHHHHHHHHHHHCCHHHHHH
ARMRPQDIDRFVPHQANSRIFDAVGRSLGIADQAIVKTIANYGNSSAATIPLSLSLANQT
HHCCHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCC
EPFRSGEKILLAAAGAGLSGGALVVGI
CCCCCCCEEEEEEECCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA