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The map label for this gene is slt [H]

Identifier: 13476427

GI number: 13476427

Start: 6414579

End: 6416609

Strand: Reverse

Name: slt [H]

Synonym: mll7744

Alternate gene names: 13476427

Gene position: 6416609-6414579 (Counterclockwise)

Preceding gene: 13476431

Following gene: 13476426

Centisome position: 91.2

GC content: 65.19

Gene sequence:

>2031_bases
ATGCCGACCCGTCGGCCTCACCTCTTCGCGCTGCTTGGCGCGATCGCCGCGCTGATGCCCGGTGTGGCGATCAGCGGCAG
CGTGGATGCGCGGGCCACCTCGGCGATCCCGATGCCGAGCCCGCAGGACAGCGCGCAGCAGGCCCCCTCACCCAGCGTCG
CGCTGTTGAAAACTGGGCTCGACGCACTGGCCGCCGGCGACATTGCCGGCGCTCGGGGTGTGCGCGATGCGCTTCCCGCT
CAATCGCTCGACCAGCACATACTGGCCTGGGCGATCGCACTTTACGGAGGCGACAAGGTTCCAAGCGGCGACATCGCCGC
CGCCGCGAAAATGCTGCCCAACTGGCCGGGCACCATTGCCTTGCGCAAGAACAGCGAGCGGGCGCTCTATCGAGAAAACC
CGGCTCCCGACATCGTCATTGCGGCATTCGATGGCAGCCAGCCGCAAACATTCGAAGGCGTCATGGTTCTCGCCCGCGCC
TATGTGGCGACGGGCAATGTCAAGGCGGCGCGTTCGGTGCTGTCGCCGTTCTGGCGCACCACGATCCTGGAAGCCAAGGA
CGAGACGGCGCTGATCAAGGAATTCGGCAGTCTGATCCCTGCCGCCGACCACCGTTTTCGCATGGACCGCATGTTCTATG
CCGACCGGGTGAATTCCGCGCTGCGCATTGCCGGCCTTGCCGGCGCCCAGCAGTTTGCCGAGGCCTGGGCCGCGGCCGAC
AGAGGCGACAAGAATGCGCTGAAACTGCTGAAGGCCGTCCCGGCGTCCCAGCGTTCTGCCGGCTATTTCTTCGCGCAGGC
CGAGTATCTGCGCAAGCAGGAGGATTTTGCCGGCGCCGCCGCCATCGTGATGAAGGCGCCGACGGACCGTGAGGCTCTGG
TCGATCCGGACGCCTGGTGGGTCGAGCGCCGGGTGCTGTCGCGCGAACTGGTCGACCAGGGCGACATGAAGACGGCGTAC
AAGATTGTCGCCACGCATGCCGCCGAAAGCGCTGCCAATGCGGCCGAGGCCGAGTTCCATGCCGGCTGGTATGCGCTGCG
GGGCCTGAACGACCCCAAGCTTGCCGCGACGCATTTTTCGCGCATCGCCGACCTTGCCCAAGGGCCGATGACCCTGTCGC
GCGCCTATTACTGGCTCGGCCGCGCCGCGGAAGTCGGCGGCCCCGGCAATGCCAAGGACTATTTTGGGCGCGCCGCCACT
TACGGCACGACCTTTTACGGCCAGCTTGCCGCCGAACGCGTCGGTCGCCAGGCGCTCAACATCGTCTATCCCACGCCAAG
TGCCGCCGACCGGCAGAATTTTGCCGGCCGCGAAGCTGTCAGCGCGATCAAGCGGCTGCAGGAGGCAGGCTATGATCGCT
ATGCCGAAACGCTCTATCGCGACCTTGCCGGCCAGTTGACCAGCCCGGGCGAACTGGCGCTGCTTGCTGTCCTTGCCGAA
AAACAGGACAACCACTTCATGGCGCTGAAGGTCGGCAAGATCGCCGGCGCGCGCGGCATCGATGTCGGTGCGCTGTCGCA
CCCGCTCGGCGTCATCCCTGATTCGGCCAATATTTCCGGTTCGGGCAAGGCGTTGGCCTATGCGATTGCCCGTCAGGAGA
GCGAATTCAACGTCGGCGCCGTATCCAGCGCCGGCGCGCGCGGGCTGCTGCAGCTGATGCCGGGAACCGCCAAACAGCTG
GCGAAGAGGGCCGGATTGCAGTTTTCGCAGGCGCGGCTGACCACCGACGCCGGCTATAACGCGACACTCGGTTCGGCCTT
CCTCGGCGAGCAGCTCGATCGCTTCAACGGCTCCTACGTGCTGACCTTCGCCGGCTACAATGCCGGCCCCAACCGGGCCA
GCCAGTGGGTGGCGAAATACGGCGATCCGCGCGGCAAGGACATCGATGCGGTGGTGGACTGGATCGAACGGATTCCCTAC
ACGGAAACAAGAAGTTACGTGCAGCGCGTGATGGAGAATTACGAAGTCTACAAGATGCGTATTTCCGGCAAATACGATAT
CATCGGCGACCTCGTGAACGGGCGCAGTTGA

Upstream 100 bases:

>100_bases
TCGATAACTCTTTGTTTACGAGCCCTTCACGACCTAAGTTTAGGCTTCGAGGCATCTTCGCCTGCTGGTAGAATGCGGGA
CTAGGGAAAGACACGAGATC

Downstream 100 bases:

>100_bases
GAGGCTCGATAGCAGCTCCGCTGCCGATCTCACTGATGGCCGGCAGTCCAGGCGGAGTGGGATTTCCAACCTTTGCATGG
CTCATGTCACGTCACCGGCA

Product: soluble lytic murein transglycosylase precursor

Products: 1,6-Anhydrobond [C]

Alternate protein names: Peptidoglycan lytic exotransglycosylase [H]

Number of amino acids: Translated: 676; Mature: 675

Protein sequence:

>676_residues
MPTRRPHLFALLGAIAALMPGVAISGSVDARATSAIPMPSPQDSAQQAPSPSVALLKTGLDALAAGDIAGARGVRDALPA
QSLDQHILAWAIALYGGDKVPSGDIAAAAKMLPNWPGTIALRKNSERALYRENPAPDIVIAAFDGSQPQTFEGVMVLARA
YVATGNVKAARSVLSPFWRTTILEAKDETALIKEFGSLIPAADHRFRMDRMFYADRVNSALRIAGLAGAQQFAEAWAAAD
RGDKNALKLLKAVPASQRSAGYFFAQAEYLRKQEDFAGAAAIVMKAPTDREALVDPDAWWVERRVLSRELVDQGDMKTAY
KIVATHAAESAANAAEAEFHAGWYALRGLNDPKLAATHFSRIADLAQGPMTLSRAYYWLGRAAEVGGPGNAKDYFGRAAT
YGTTFYGQLAAERVGRQALNIVYPTPSAADRQNFAGREAVSAIKRLQEAGYDRYAETLYRDLAGQLTSPGELALLAVLAE
KQDNHFMALKVGKIAGARGIDVGALSHPLGVIPDSANISGSGKALAYAIARQESEFNVGAVSSAGARGLLQLMPGTAKQL
AKRAGLQFSQARLTTDAGYNATLGSAFLGEQLDRFNGSYVLTFAGYNAGPNRASQWVAKYGDPRGKDIDAVVDWIERIPY
TETRSYVQRVMENYEVYKMRISGKYDIIGDLVNGRS

Sequences:

>Translated_676_residues
MPTRRPHLFALLGAIAALMPGVAISGSVDARATSAIPMPSPQDSAQQAPSPSVALLKTGLDALAAGDIAGARGVRDALPA
QSLDQHILAWAIALYGGDKVPSGDIAAAAKMLPNWPGTIALRKNSERALYRENPAPDIVIAAFDGSQPQTFEGVMVLARA
YVATGNVKAARSVLSPFWRTTILEAKDETALIKEFGSLIPAADHRFRMDRMFYADRVNSALRIAGLAGAQQFAEAWAAAD
RGDKNALKLLKAVPASQRSAGYFFAQAEYLRKQEDFAGAAAIVMKAPTDREALVDPDAWWVERRVLSRELVDQGDMKTAY
KIVATHAAESAANAAEAEFHAGWYALRGLNDPKLAATHFSRIADLAQGPMTLSRAYYWLGRAAEVGGPGNAKDYFGRAAT
YGTTFYGQLAAERVGRQALNIVYPTPSAADRQNFAGREAVSAIKRLQEAGYDRYAETLYRDLAGQLTSPGELALLAVLAE
KQDNHFMALKVGKIAGARGIDVGALSHPLGVIPDSANISGSGKALAYAIARQESEFNVGAVSSAGARGLLQLMPGTAKQL
AKRAGLQFSQARLTTDAGYNATLGSAFLGEQLDRFNGSYVLTFAGYNAGPNRASQWVAKYGDPRGKDIDAVVDWIERIPY
TETRSYVQRVMENYEVYKMRISGKYDIIGDLVNGRS
>Mature_675_residues
PTRRPHLFALLGAIAALMPGVAISGSVDARATSAIPMPSPQDSAQQAPSPSVALLKTGLDALAAGDIAGARGVRDALPAQ
SLDQHILAWAIALYGGDKVPSGDIAAAAKMLPNWPGTIALRKNSERALYRENPAPDIVIAAFDGSQPQTFEGVMVLARAY
VATGNVKAARSVLSPFWRTTILEAKDETALIKEFGSLIPAADHRFRMDRMFYADRVNSALRIAGLAGAQQFAEAWAAADR
GDKNALKLLKAVPASQRSAGYFFAQAEYLRKQEDFAGAAAIVMKAPTDREALVDPDAWWVERRVLSRELVDQGDMKTAYK
IVATHAAESAANAAEAEFHAGWYALRGLNDPKLAATHFSRIADLAQGPMTLSRAYYWLGRAAEVGGPGNAKDYFGRAATY
GTTFYGQLAAERVGRQALNIVYPTPSAADRQNFAGREAVSAIKRLQEAGYDRYAETLYRDLAGQLTSPGELALLAVLAEK
QDNHFMALKVGKIAGARGIDVGALSHPLGVIPDSANISGSGKALAYAIARQESEFNVGAVSSAGARGLLQLMPGTAKQLA
KRAGLQFSQARLTTDAGYNATLGSAFLGEQLDRFNGSYVLTFAGYNAGPNRASQWVAKYGDPRGKDIDAVVDWIERIPYT
ETRSYVQRVMENYEVYKMRISGKYDIIGDLVNGRS

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI87082441, Length=258, Percent_Identity=31.7829457364341, Blast_Score=89, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011989
- InterPro:   IPR016026
- InterPro:   IPR008258
- InterPro:   IPR012289
- InterPro:   IPR008939
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 72484; Mature: 72353

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTRRPHLFALLGAIAALMPGVAISGSVDARATSAIPMPSPQDSAQQAPSPSVALLKTGL
CCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHCH
DALAAGDIAGARGVRDALPAQSLDQHILAWAIALYGGDKVPSGDIAAAAKMLPNWPGTIA
HHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEE
LRKNSERALYRENPAPDIVIAAFDGSQPQTFEGVMVLARAYVATGNVKAARSVLSPFWRT
EECCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
TILEAKDETALIKEFGSLIPAADHRFRMDRMFYADRVNSALRIAGLAGAQQFAEAWAAAD
HHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
RGDKNALKLLKAVPASQRSAGYFFAQAEYLRKQEDFAGAAAIVMKAPTDREALVDPDAWW
CCCHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCHHHH
VERRVLSRELVDQGDMKTAYKIVATHAAESAANAAEAEFHAGWYALRGLNDPKLAATHFS
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCHHEECCCCCCHHHHHHHH
RIADLAQGPMTLSRAYYWLGRAAEVGGPGNAKDYFGRAATYGTTFYGQLAAERVGRQALN
HHHHHHCCCHHHHHHHHHHCCHHCCCCCCCCHHHCCCHHHCCHHHHHHHHHHHHCHHHEE
IVYPTPSAADRQNFAGREAVSAIKRLQEAGYDRYAETLYRDLAGQLTSPGELALLAVLAE
EEECCCCCCCHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
KQDNHFMALKVGKIAGARGIDVGALSHPLGVIPDSANISGSGKALAYAIARQESEFNVGA
CCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHCCCCCCCCC
VSSAGARGLLQLMPGTAKQLAKRAGLQFSQARLTTDAGYNATLGSAFLGEQLDRFNGSYV
CCCCCHHHHHHHCCCHHHHHHHHHCCCCHHHEEECCCCCCCCHHHHHHHHHHHHCCCCEE
LTFAGYNAGPNRASQWVAKYGDPRGKDIDAVVDWIERIPYTETRSYVQRVMENYEVYKMR
EEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEE
ISGKYDIIGDLVNGRS
ECCCCHHHHHHCCCCC
>Mature Secondary Structure 
PTRRPHLFALLGAIAALMPGVAISGSVDARATSAIPMPSPQDSAQQAPSPSVALLKTGL
CCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHCH
DALAAGDIAGARGVRDALPAQSLDQHILAWAIALYGGDKVPSGDIAAAAKMLPNWPGTIA
HHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEE
LRKNSERALYRENPAPDIVIAAFDGSQPQTFEGVMVLARAYVATGNVKAARSVLSPFWRT
EECCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
TILEAKDETALIKEFGSLIPAADHRFRMDRMFYADRVNSALRIAGLAGAQQFAEAWAAAD
HHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
RGDKNALKLLKAVPASQRSAGYFFAQAEYLRKQEDFAGAAAIVMKAPTDREALVDPDAWW
CCCHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCHHHH
VERRVLSRELVDQGDMKTAYKIVATHAAESAANAAEAEFHAGWYALRGLNDPKLAATHFS
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCHHEECCCCCCHHHHHHHH
RIADLAQGPMTLSRAYYWLGRAAEVGGPGNAKDYFGRAATYGTTFYGQLAAERVGRQALN
HHHHHHCCCHHHHHHHHHHCCHHCCCCCCCCHHHCCCHHHCCHHHHHHHHHHHHCHHHEE
IVYPTPSAADRQNFAGREAVSAIKRLQEAGYDRYAETLYRDLAGQLTSPGELALLAVLAE
EEECCCCCCCHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
KQDNHFMALKVGKIAGARGIDVGALSHPLGVIPDSANISGSGKALAYAIARQESEFNVGA
CCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHCCCCCCCCC
VSSAGARGLLQLMPGTAKQLAKRAGLQFSQARLTTDAGYNATLGSAFLGEQLDRFNGSYV
CCCCCHHHHHHHCCCHHHHHHHHHCCCCHHHEEECCCCCCCCHHHHHHHHHHHHCCCCEE
LTFAGYNAGPNRASQWVAKYGDPRGKDIDAVVDWIERIPYTETRSYVQRVMENYEVYKMR
EEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEE
ISGKYDIIGDLVNGRS
ECCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]