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The map label for this gene is cutL [H]

Identifier: 13476394

GI number: 13476394

Start: 6379735

End: 6382086

Strand: Direct

Name: cutL [H]

Synonym: mlr7702

Alternate gene names: 13476394

Gene position: 6379735-6382086 (Clockwise)

Preceding gene: 13476391

Following gene: 13476395

Centisome position: 90.67

GC content: 63.9

Gene sequence:

>2352_bases
ATGCCTATTTCAGGCGTTCGTTCTCCACATCCCCGCGAGGCAGCCATGACCGTCGTCACACCGAAATTCGGCATGGGCGC
TTCCGTGCTGCGGCGCGAGGATGCCGCCTTCATCCAGGGTCAGGGCCGCTATACCGACGATATCCAGCCCGCCGGCGTCC
TGCACGGCTATGTTCTGCGCTCGCCGATCGCCAAGGCGAGCTTTACCATCGGCTCGATCGAGGCGGCGAAGGCGGCACCC
GGCGTCCATCTGGTGCTGACCGGTGGGGATCTCACCCATCTGCGCGATCTCAAGTCCGGCGTCATGCAGCCACAGCCGGA
CGGCACCAAAGCGCCGACGCGCGACATTCCGATCCTGTGCCGGGACCGCGTCAACTATGTCGGCGATGCGGTTGCCTTTG
TCGTCGCCGACAGCCGTGCCTTGGCGCAGGATGCCGCCGAACTGATCGAGGTCGATTATGACGGCGAGGACGCCGCCTCA
GGCACGGCGACGGCGCTTGCCGAGGGCACGCCGCTGGTCTGGCCGGAACTCGGCTCCAACCGCGCCTTCACCTATCATAT
GGGCGACAAGAAAAAGACGGACGCGGCTTTCGCTGGGGCCGCTCACGTCACTCGCATCGAATTCGTCAACAATCGGCTGG
TCTGCAACTACATGGAGCCGCGCTCGGCGATCGGCGAATGGAATGTCGGGGAAAACCGCTTCGTGCTGACCACCGGGTCG
CAGGGCGTGCATTCCATGCAGTACATCCTGGCCAGTGTGTTCAAGATCAAGAAGGACCAACTGCGCGTCATCACGCCCGA
TGTCGGCGGCGGTTTCGGGCCGAAGAGCTTCGTCTACCGCGAATATCCGCTGGTGCTCGAGGCGGCGAAGCGGCTTGGCC
GTCCGGTGAAATGGGCCGGCGACCGCACCGAGCACTTCCTCACCGACGCCCAAGGCCGCGACAATGCGGTGACGGCCGAG
ATGGCGCTCGACAAGGATGGCCGCTTCCTCGGCATGAGGGTCGATCTGCTTGCCAATATCGGCGCCTATATCTCGCAATA
TGGCCCTTTCATTCCGTATATCGGCGTCACCATGTCGACCGGCGTCTATGATATCAGGGCGCTCGATGTCTCGGTGACCG
GCCTCTACACCAACACCTGCCCGGTCGACGCTTATCGCGGCGCCGGCCGTCCCGAGGCGGCGTTCCTGTTGGAAAAACTT
GTCGATGCCTGCGCGCATGATCTCGGCCTGCCTGTCGAAGAGATCCGCCGCCGCAACTTCATTCGGCCCGAGCAGTTTCC
CTATCGCACGCAGACCGGCCGGCTCTACGACAATGGCGAATTCGAAGGCCATATGGACCGCGCCATCGAACGGTCGCAGT
GGAAGGCGTTTCCGCAGCGGCTGGAGCAGTCCAAAGCCGATGGCAAGATCCGCGGCATCGGTATGGCCACCTATATCGAG
GCCTGCGCCTTTCCGGGCTCCGAACCGGCCTTTGTCGAGCTCAATGGCGACGGCACGGTGACGCTGAAGATCGGCACCCA
GACCAACGGCCAGGGGCATGCCACCGCCTATGCGCAGTTCCTGTCGGAAAAACTCAATCTCGACATCGACAAGATCCATG
TCCGCCAGGGCGACACCGACGAATTGAAGGCGGGCGGCGGCACAGGCGGCTCGCGCTCCATTCCGCTGGGGGGTGTCTCG
GCTTCCCGCGCCGGTGAGGACCTGGCCAACAAGATCAAGCGCATCGCCGCCGATGAGCTTGAGGCCTCGGCCGGCGATAT
CGAACTGTCCGATGGTGTTGCCCGCATCGTCGGCACCGACCGGAGCATCGATTTCTCGAGCATCGCCAAGGCTGCGAAGA
CGCCGGATGACCTTAAGGGATTCGGCGAGTTCGTACAGGACGAGTGCACCTATCCGAACGGCACCCACATCTGCGAGGTC
GAGATCGATCCCGACACCGGCGCGACCGAGATTGTCCGCTACACCATCGTCGACGATTTCGGCGTCACGGTGAATCCGAT
CCTGCTCGCAGGCCAGGTGCATGGCGGCGTCGTGCAAGGCATCGGCCAGGCGTTGACCGAGAACACCATCCATGGCGAGG
ATGGGCAGCTCTTGACGGCGAGCTTCATGGACTACGCCATGCCGCGCGCCGACAATTTCCCGTTCTTCCATTTCGAGACC
CGCAACGTGCCTTCAACCACCAATGCGCTGGGCATCAAGGGCGCGGGCGAGGCCGGCACGATCGGCTCGACACCGGCGGC
GCTCAACGCCGTCACCGATGCGCTGTGGCGCGCCTATGGCATCAGGCATATCGAGATGCCGGCGACGCCGGCGCGCATCT
GGGCCGCGATCAGGGGCGCATCGCCGACGTGA

Upstream 100 bases:

>100_bases
TTTTTCCTGTCGATTGCGTTGGACGCGGAGTTCCCGCTGGTCCAAGAAATTTGAAGTCCGCGCTCTTTACACGAAATGGT
CCCTCGACAAAACTCGGCCG

Downstream 100 bases:

>100_bases
CATCAGGGGCGGAACCAGGAACGACGGGCGGCCACGGCACGCTGAGGGGGATCGCGCTGAAGATCGTCTCGGTGGCGGTT
TTTGTCGGCATGCAAACCTG

Product: putative dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 783; Mature: 782

Protein sequence:

>783_residues
MPISGVRSPHPREAAMTVVTPKFGMGASVLRREDAAFIQGQGRYTDDIQPAGVLHGYVLRSPIAKASFTIGSIEAAKAAP
GVHLVLTGGDLTHLRDLKSGVMQPQPDGTKAPTRDIPILCRDRVNYVGDAVAFVVADSRALAQDAAELIEVDYDGEDAAS
GTATALAEGTPLVWPELGSNRAFTYHMGDKKKTDAAFAGAAHVTRIEFVNNRLVCNYMEPRSAIGEWNVGENRFVLTTGS
QGVHSMQYILASVFKIKKDQLRVITPDVGGGFGPKSFVYREYPLVLEAAKRLGRPVKWAGDRTEHFLTDAQGRDNAVTAE
MALDKDGRFLGMRVDLLANIGAYISQYGPFIPYIGVTMSTGVYDIRALDVSVTGLYTNTCPVDAYRGAGRPEAAFLLEKL
VDACAHDLGLPVEEIRRRNFIRPEQFPYRTQTGRLYDNGEFEGHMDRAIERSQWKAFPQRLEQSKADGKIRGIGMATYIE
ACAFPGSEPAFVELNGDGTVTLKIGTQTNGQGHATAYAQFLSEKLNLDIDKIHVRQGDTDELKAGGGTGGSRSIPLGGVS
ASRAGEDLANKIKRIAADELEASAGDIELSDGVARIVGTDRSIDFSSIAKAAKTPDDLKGFGEFVQDECTYPNGTHICEV
EIDPDTGATEIVRYTIVDDFGVTVNPILLAGQVHGGVVQGIGQALTENTIHGEDGQLLTASFMDYAMPRADNFPFFHFET
RNVPSTTNALGIKGAGEAGTIGSTPAALNAVTDALWRAYGIRHIEMPATPARIWAAIRGASPT

Sequences:

>Translated_783_residues
MPISGVRSPHPREAAMTVVTPKFGMGASVLRREDAAFIQGQGRYTDDIQPAGVLHGYVLRSPIAKASFTIGSIEAAKAAP
GVHLVLTGGDLTHLRDLKSGVMQPQPDGTKAPTRDIPILCRDRVNYVGDAVAFVVADSRALAQDAAELIEVDYDGEDAAS
GTATALAEGTPLVWPELGSNRAFTYHMGDKKKTDAAFAGAAHVTRIEFVNNRLVCNYMEPRSAIGEWNVGENRFVLTTGS
QGVHSMQYILASVFKIKKDQLRVITPDVGGGFGPKSFVYREYPLVLEAAKRLGRPVKWAGDRTEHFLTDAQGRDNAVTAE
MALDKDGRFLGMRVDLLANIGAYISQYGPFIPYIGVTMSTGVYDIRALDVSVTGLYTNTCPVDAYRGAGRPEAAFLLEKL
VDACAHDLGLPVEEIRRRNFIRPEQFPYRTQTGRLYDNGEFEGHMDRAIERSQWKAFPQRLEQSKADGKIRGIGMATYIE
ACAFPGSEPAFVELNGDGTVTLKIGTQTNGQGHATAYAQFLSEKLNLDIDKIHVRQGDTDELKAGGGTGGSRSIPLGGVS
ASRAGEDLANKIKRIAADELEASAGDIELSDGVARIVGTDRSIDFSSIAKAAKTPDDLKGFGEFVQDECTYPNGTHICEV
EIDPDTGATEIVRYTIVDDFGVTVNPILLAGQVHGGVVQGIGQALTENTIHGEDGQLLTASFMDYAMPRADNFPFFHFET
RNVPSTTNALGIKGAGEAGTIGSTPAALNAVTDALWRAYGIRHIEMPATPARIWAAIRGASPT
>Mature_782_residues
PISGVRSPHPREAAMTVVTPKFGMGASVLRREDAAFIQGQGRYTDDIQPAGVLHGYVLRSPIAKASFTIGSIEAAKAAPG
VHLVLTGGDLTHLRDLKSGVMQPQPDGTKAPTRDIPILCRDRVNYVGDAVAFVVADSRALAQDAAELIEVDYDGEDAASG
TATALAEGTPLVWPELGSNRAFTYHMGDKKKTDAAFAGAAHVTRIEFVNNRLVCNYMEPRSAIGEWNVGENRFVLTTGSQ
GVHSMQYILASVFKIKKDQLRVITPDVGGGFGPKSFVYREYPLVLEAAKRLGRPVKWAGDRTEHFLTDAQGRDNAVTAEM
ALDKDGRFLGMRVDLLANIGAYISQYGPFIPYIGVTMSTGVYDIRALDVSVTGLYTNTCPVDAYRGAGRPEAAFLLEKLV
DACAHDLGLPVEEIRRRNFIRPEQFPYRTQTGRLYDNGEFEGHMDRAIERSQWKAFPQRLEQSKADGKIRGIGMATYIEA
CAFPGSEPAFVELNGDGTVTLKIGTQTNGQGHATAYAQFLSEKLNLDIDKIHVRQGDTDELKAGGGTGGSRSIPLGGVSA
SRAGEDLANKIKRIAADELEASAGDIELSDGVARIVGTDRSIDFSSIAKAAKTPDDLKGFGEFVQDECTYPNGTHICEVE
IDPDTGATEIVRYTIVDDFGVTVNPILLAGQVHGGVVQGIGQALTENTIHGEDGQLLTASFMDYAMPRADNFPFFHFETR
NVPSTTNALGIKGAGEAGTIGSTPAALNAVTDALWRAYGIRHIEMPATPARIWAAIRGASPT

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=781, Percent_Identity=23.943661971831, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI91823271, Length=690, Percent_Identity=24.4927536231884, Blast_Score=124, Evalue=4e-28,
Organism=Escherichia coli, GI1789246, Length=814, Percent_Identity=26.044226044226, Blast_Score=209, Evalue=5e-55,
Organism=Escherichia coli, GI1789230, Length=773, Percent_Identity=28.4605433376455, Blast_Score=206, Evalue=6e-54,
Organism=Escherichia coli, GI1786478, Length=726, Percent_Identity=24.3801652892562, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17540638, Length=772, Percent_Identity=24.740932642487, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17539860, Length=764, Percent_Identity=25.261780104712, Blast_Score=139, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI32566215, Length=568, Percent_Identity=25.8802816901408, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17737937, Length=767, Percent_Identity=22.8161668839635, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24647199, Length=730, Percent_Identity=21.7808219178082, Blast_Score=91, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 84200; Mature: 84069

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPISGVRSPHPREAAMTVVTPKFGMGASVLRREDAAFIQGQGRYTDDIQPAGVLHGYVLR
CCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHH
SPIAKASFTIGSIEAAKAAPGVHLVLTGGDLTHLRDLKSGVMQPQPDGTKAPTRDIPILC
CCHHHHEEEECCCCHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
RDRVNYVGDAVAFVVADSRALAQDAAELIEVDYDGEDAASGTATALAEGTPLVWPELGSN
HHHHHHHHHEEEEEEECCHHHHHHHHHHEEECCCCCCCCCCCHHHHCCCCCEECCCCCCC
RAFTYHMGDKKKTDAAFAGAAHVTRIEFVNNRLVCNYMEPRSAIGEWNVGENRFVLTTGS
CEEEEECCCCCCCCHHHCCCHHEEEEEEECCEEEEEECCHHHHCCCCCCCCCEEEEECCC
QGVHSMQYILASVFKIKKDQLRVITPDVGGGFGPKSFVYREYPLVLEAAKRLGRPVKWAG
CCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEECCHHHHHHHHHHCCCEECCC
DRTEHFLTDAQGRDNAVTAEMALDKDGRFLGMRVDLLANIGAYISQYGPFIPYIGVTMST
CCHHHHHCCCCCCCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCEEECC
GVYDIRALDVSVTGLYTNTCPVDAYRGAGRPEAAFLLEKLVDACAHDLGLPVEEIRRRNF
CEEEEEEEEEEEEEEEECCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
IRPEQFPYRTQTGRLYDNGEFEGHMDRAIERSQWKAFPQRLEQSKADGKIRGIGMATYIE
CCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHH
ACAFPGSEPAFVELNGDGTVTLKIGTQTNGQGHATAYAQFLSEKLNLDIDKIHVRQGDTD
HHCCCCCCCEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHH
ELKAGGGTGGSRSIPLGGVSASRAGEDLANKIKRIAADELEASAGDIELSDGVARIVGTD
HHCCCCCCCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEEECC
RSIDFSSIAKAAKTPDDLKGFGEFVQDECTYPNGTHICEVEIDPDTGATEIVRYTIVDDF
CCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEEECC
GVTVNPILLAGQVHGGVVQGIGQALTENTIHGEDGQLLTASFMDYAMPRADNFPFFHFET
CCEECCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHCCCCCCCCEEEEEC
RNVPSTTNALGIKGAGEAGTIGSTPAALNAVTDALWRAYGIRHIEMPATPARIWAAIRGA
CCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHCCC
SPT
CCC
>Mature Secondary Structure 
PISGVRSPHPREAAMTVVTPKFGMGASVLRREDAAFIQGQGRYTDDIQPAGVLHGYVLR
CCCCCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHH
SPIAKASFTIGSIEAAKAAPGVHLVLTGGDLTHLRDLKSGVMQPQPDGTKAPTRDIPILC
CCHHHHEEEECCCCHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
RDRVNYVGDAVAFVVADSRALAQDAAELIEVDYDGEDAASGTATALAEGTPLVWPELGSN
HHHHHHHHHEEEEEEECCHHHHHHHHHHEEECCCCCCCCCCCHHHHCCCCCEECCCCCCC
RAFTYHMGDKKKTDAAFAGAAHVTRIEFVNNRLVCNYMEPRSAIGEWNVGENRFVLTTGS
CEEEEECCCCCCCCHHHCCCHHEEEEEEECCEEEEEECCHHHHCCCCCCCCCEEEEECCC
QGVHSMQYILASVFKIKKDQLRVITPDVGGGFGPKSFVYREYPLVLEAAKRLGRPVKWAG
CCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEECCHHHHHHHHHHCCCEECCC
DRTEHFLTDAQGRDNAVTAEMALDKDGRFLGMRVDLLANIGAYISQYGPFIPYIGVTMST
CCHHHHHCCCCCCCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCEEECC
GVYDIRALDVSVTGLYTNTCPVDAYRGAGRPEAAFLLEKLVDACAHDLGLPVEEIRRRNF
CEEEEEEEEEEEEEEEECCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
IRPEQFPYRTQTGRLYDNGEFEGHMDRAIERSQWKAFPQRLEQSKADGKIRGIGMATYIE
CCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHH
ACAFPGSEPAFVELNGDGTVTLKIGTQTNGQGHATAYAQFLSEKLNLDIDKIHVRQGDTD
HHCCCCCCCEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHH
ELKAGGGTGGSRSIPLGGVSASRAGEDLANKIKRIAADELEASAGDIELSDGVARIVGTD
HHCCCCCCCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEEECC
RSIDFSSIAKAAKTPDDLKGFGEFVQDECTYPNGTHICEVEIDPDTGATEIVRYTIVDDF
CCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEEECC
GVTVNPILLAGQVHGGVVQGIGQALTENTIHGEDGQLLTASFMDYAMPRADNFPFFHFET
CCEECCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHCCCCCCCCEEEEEC
RNVPSTTNALGIKGAGEAGTIGSTPAALNAVTDALWRAYGIRHIEMPATPARIWAAIRGA
CCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHCCC
SPT
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]