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The map label for this gene is rfbC [C]

Identifier: 13476272

GI number: 13476272

Start: 6232935

End: 6233486

Strand: Direct

Name: rfbC [C]

Synonym: mlr7551

Alternate gene names: 13476272

Gene position: 6232935-6233486 (Clockwise)

Preceding gene: 13476271

Following gene: 13476273

Centisome position: 88.59

GC content: 59.06

Gene sequence:

>552_bases
TTGGAGATCAGGTCCCTCGGCATCGATGGCGTGCTGGAAATCGTTCCCAAGCGACATGGCGATGCACGCGGCTTCTTCAT
GGAAACCTACAATGCCGAGCGGTTTTCGCAGGCAGGCATCGACTTGGTTTTCGTGCAGGACAACCATTCCTATTCCGCTA
CGGCAGGCGTCTTGCGAGGGCTTCACTACCAGCTCGAGCCGCGGGCCCAGGACAAGCTGCTGCGCGTCATTCGCGGCAGT
ATCCTCGACGTTGCGGTCGATATCCGCCGTGGTTCGAAAACCTTTGGGAAATGGGTCGCCTGCGAGATTTCGGCCGAAAA
GGGCAATCAGATCCTGGTGCCAAAGGGTTTCGCGCATGGCTTTGTGACGCTCGTGCCCGACACCGAGGTTCTCTATAAGG
TTACCGACACTTATTCGCCCGAGCACGATCGGTCCGTCCGCTTCGACGATCCCGTCATCGGCATCGAATGGCCTTCAGTG
GCTGGCGGATTCCAGCTTTCGGACAAGGACCTCAAGGCGCCGGTGCTCGCCGAGGCCGAAGTGTTTGCCTGA

Upstream 100 bases:

>100_bases
GACGGCGGAGCAAGTGCTGCAACGCGCAACCCGGTTGGGCAAAAATGAATATGCCGCCTATCTGCGGCGGCGCGTCGCCG
ATCTGTTGGAGGGCTAAGCT

Downstream 100 bases:

>100_bases
TGGGCATGAGGATAGCGGCATGAATTTTCTGGTGACAGGCGGGGCTGGCTTCATCGGTTCGGCGGTGTGTCGGCATCTGT
GCGCCAATCCGGCCTATCGG

Product: dTDP-6-deoxy-D-glucose-3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MEIRSLGIDGVLEIVPKRHGDARGFFMETYNAERFSQAGIDLVFVQDNHSYSATAGVLRGLHYQLEPRAQDKLLRVIRGS
ILDVAVDIRRGSKTFGKWVACEISAEKGNQILVPKGFAHGFVTLVPDTEVLYKVTDTYSPEHDRSVRFDDPVIGIEWPSV
AGGFQLSDKDLKAPVLAEAEVFA

Sequences:

>Translated_183_residues
MEIRSLGIDGVLEIVPKRHGDARGFFMETYNAERFSQAGIDLVFVQDNHSYSATAGVLRGLHYQLEPRAQDKLLRVIRGS
ILDVAVDIRRGSKTFGKWVACEISAEKGNQILVPKGFAHGFVTLVPDTEVLYKVTDTYSPEHDRSVRFDDPVIGIEWPSV
AGGFQLSDKDLKAPVLAEAEVFA
>Mature_183_residues
MEIRSLGIDGVLEIVPKRHGDARGFFMETYNAERFSQAGIDLVFVQDNHSYSATAGVLRGLHYQLEPRAQDKLLRVIRGS
ILDVAVDIRRGSKTFGKWVACEISAEKGNQILVPKGFAHGFVTLVPDTEVLYKVTDTYSPEHDRSVRFDDPVIGIEWPSV
AGGFQLSDKDLKAPVLAEAEVFA

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=179, Percent_Identity=45.8100558659218, Blast_Score=149, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17550412, Length=154, Percent_Identity=39.6103896103896, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20276; Mature: 20276

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIRSLGIDGVLEIVPKRHGDARGFFMETYNAERFSQAGIDLVFVQDNHSYSATAGVLRG
CCCHHCCCCHHEEEECCCCCCCCEEEEEECCCHHHHHCCEEEEEEECCCCCHHHHHHHHC
LHYQLEPRAQDKLLRVIRGSILDVAVDIRRGSKTFGKWVACEISAEKGNQILVPKGFAHG
CCEEECCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEEEECCCCCEEEEECCCCCC
FVTLVPDTEVLYKVTDTYSPEHDRSVRFDDPVIGIEWPSVAGGFQLSDKDLKAPVLAEAE
EEEEECCCCEEEEEECCCCCCCCCCEECCCCEEEEECCCCCCCEEECCCCCCCCEECCCE
VFA
ECC
>Mature Secondary Structure
MEIRSLGIDGVLEIVPKRHGDARGFFMETYNAERFSQAGIDLVFVQDNHSYSATAGVLRG
CCCHHCCCCHHEEEECCCCCCCCEEEEEECCCHHHHHCCEEEEEEECCCCCHHHHHHHHC
LHYQLEPRAQDKLLRVIRGSILDVAVDIRRGSKTFGKWVACEISAEKGNQILVPKGFAHG
CCEEECCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEEEECCCCCEEEEECCCCCC
FVTLVPDTEVLYKVTDTYSPEHDRSVRFDDPVIGIEWPSVAGGFQLSDKDLKAPVLAEAE
EEEEECCCCEEEEEECCCCCCCCCCEECCCCEEEEECCCCCCCEEECCCCCCCCEECCCE
VFA
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]