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The map label for this gene is 13476239

Identifier: 13476239

GI number: 13476239

Start: 6196249

End: 6196731

Strand: Reverse

Name: 13476239

Synonym: mll7508

Alternate gene names: NA

Gene position: 6196731-6196249 (Counterclockwise)

Preceding gene: 13476240

Following gene: 13476238

Centisome position: 88.07

GC content: 62.32

Gene sequence:

>483_bases
ATGACCATTTCCGTTGGCGACAAGCTGCCTGAAGCGACCTTCAAGACGATGACCGCCGACGGCGCCAAGGCGATCACCTC
GGCCGAGATTTTCCCGGGCAAGAAGGTGGTTCTGTTCGGTGTTCCCGGCGCCTTCACGCCGACCTGCAGCAACAACCATC
TGCCCGGCTATCTCGAAAACCATGACGCCATCCTGGCCCGCGGCGTCGACACCATCGCCGTCGTTTCGGTCAACGACGTT
CACGTCATGGGCGCCTGGGCACGTTTCACCGGCGGTGAGGACAAGATCCTGTTTCTCGCCGACGGCAGTGCTGATTTCGC
CAAGGCGGTCGGCCTCGACAACGACCTTTCCGCAGGCGGCATGGGGCTACGCTCGAAGCGGTTTTCGATGATCGTCGACG
ACGGCAAGGTCACCGCGCTCAATATCGAGACCAAGCCCGGCGTCGACGAGTCCGGCGCGGCCCATATTCTCGGGCAGCTC
TAA

Upstream 100 bases:

>100_bases
GCCTTTCCCTTGATCCAGCTTGCCCGAACGGTTGCAGGACGCCGCCGAGTTCGCTACGCAAGCATGCATTCTTCCTTCCC
ATTCCCCAAGCGAGGAACTC

Downstream 100 bases:

>100_bases
GCTTCAACGGTCGCGTCGGACGAGACCGCACGGCCGGCCTCGCCCGACGACCGCTTGCGCTTGAGAATGCCCGCTTTCGG
GGGGATTCCAACGATGTTTG

Product: peroxiredoxin-like protein

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MTISVGDKLPEATFKTMTADGAKAITSAEIFPGKKVVLFGVPGAFTPTCSNNHLPGYLENHDAILARGVDTIAVVSVNDV
HVMGAWARFTGGEDKILFLADGSADFAKAVGLDNDLSAGGMGLRSKRFSMIVDDGKVTALNIETKPGVDESGAAHILGQL

Sequences:

>Translated_160_residues
MTISVGDKLPEATFKTMTADGAKAITSAEIFPGKKVVLFGVPGAFTPTCSNNHLPGYLENHDAILARGVDTIAVVSVNDV
HVMGAWARFTGGEDKILFLADGSADFAKAVGLDNDLSAGGMGLRSKRFSMIVDDGKVTALNIETKPGVDESGAAHILGQL
>Mature_159_residues
TISVGDKLPEATFKTMTADGAKAITSAEIFPGKKVVLFGVPGAFTPTCSNNHLPGYLENHDAILARGVDTIAVVSVNDVH
VMGAWARFTGGEDKILFLADGSADFAKAVGLDNDLSAGGMGLRSKRFSMIVDDGKVTALNIETKPGVDESGAAHILGQL

Specific function: Unknown

COG id: COG0678

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI6912238, Length=161, Percent_Identity=44.7204968944099, Blast_Score=123, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6323138, Length=165, Percent_Identity=33.9393939393939, Blast_Score=84, Evalue=1e-17,
Organism=Drosophila melanogaster, GI78706776, Length=142, Percent_Identity=46.4788732394366, Blast_Score=123, Evalue=4e-29,
Organism=Drosophila melanogaster, GI78709078, Length=142, Percent_Identity=46.4788732394366, Blast_Score=123, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 16633; Mature: 16502

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISVGDKLPEATFKTMTADGAKAITSAEIFPGKKVVLFGVPGAFTPTCSNNHLPGYLEN
CEECCCCCCCCCHHEEECCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCEECC
HDAILARGVDTIAVVSVNDVHVMGAWARFTGGEDKILFLADGSADFAKAVGLDNDLSAGG
CCEEEECCCCEEEEEEECCEEEEEEEEEECCCCCEEEEEECCCCCHHHHCCCCCCCCCCC
MGLRSKRFSMIVDDGKVTALNIETKPGVDESGAAHILGQL
CCCCCCEEEEEEECCCEEEEEEECCCCCCCCCCEEEEECC
>Mature Secondary Structure 
TISVGDKLPEATFKTMTADGAKAITSAEIFPGKKVVLFGVPGAFTPTCSNNHLPGYLEN
EECCCCCCCCCHHEEECCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCEECC
HDAILARGVDTIAVVSVNDVHVMGAWARFTGGEDKILFLADGSADFAKAVGLDNDLSAGG
CCEEEECCCCEEEEEEECCEEEEEEEEEECCCCCEEEEEECCCCCHHHHCCCCCCCCCCC
MGLRSKRFSMIVDDGKVTALNIETKPGVDESGAAHILGQL
CCCCCCEEEEEEECCCEEEEEEECCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]