Click here to switch to the map view.

The map label for this gene is aroC

Identifier: 13476203

GI number: 13476203

Start: 6163965

End: 6165080

Strand: Direct

Name: aroC

Synonym: mlr7461

Alternate gene names: 13476203

Gene position: 6163965-6165080 (Clockwise)

Preceding gene: 13476201

Following gene: 13476204

Centisome position: 87.61

GC content: 64.52

Gene sequence:

>1116_bases
ATGTCTCACAACACGTTCGGCCACCTTTTCCGCGTCACCACCTGGGGCGAAAGCCATGGCGCAGCGCTTGGCTGCGTGGT
CGACGGCTGCCCGCCCGGCATCCGCTTCACGCGTGATGAAATCCAGGCCGAACTCGACAAGCGCCGGCCGGGCCAGTCGC
GCTTCGTGACCCAGCGCCGCGAACCCGACGAGGTGAAGGTGCTGTCGGGTTTCGTCCTCGACGAGGACGGCGAGACGATG
ATCACCACCGGCACGCCGGTCTCGATGCTGATCGAGAATGTCGACCAGCGATCGAAGGACTATGGCGAGATCGCCCGCCA
GTACCGGCCGGGCCATGCCGACTACACCTATGATGTCAAATACGGCATCCGCGACTATCGCGGCGGCGGCCGCTCCTCCG
CCCGCGAGACCGCGGCCAGGGTCGCCGCCGGCGCGCTCGCCCGTAAGGTGGTGCCCGGCATGGTGGTGCGCGGAGCCCTG
GTCTCGATGGGCGAAAAATCGATCGACCGCGCCAATTGGAACTGGAATTTCATCGGCGACGCGGAGAATCCGTTCTTCAC
GCCCGATCCCGCTTCGGTTCCCGTTTTTACGCAGTATCTCGACGGTATCCGCAAGGCGGGATCTTCGGTCGGCGCTGTGA
TCGAGATCGTCGCCGATGGCGTTCCGCCAGGGCTCGGCGCGCCGATCTATGCCAAGCTCGACCAGGACATTGCGTCGGGC
CTGATGTCGATCAACGCCGTCAAGGGCGTCGAGATCGGCAATGGTTTCGAGGCCGCCCGCATCACCGGTGAGCAGAATGC
CGACGAAATGCGCATCGGCAATGACGGCAAACCGGTGTTCCTCTCCAACAATGCCGGCGGCATCCTCGGCGGCATCTCGA
CCGGTCAGGCGATCGTGGCCCGCTTCGCCGTCAAGCCGACCTCGTCGATCCTGACGCCGCGAAAGTCGATCGACAAGGAC
GGCAACGACGTCGAGGTGATGACCAAGGGCCGCCATGATCCCTGTGTCGGCATCCGCGCCGTGCCGATCGGCGAAGCGAT
GGTTGCCTGCGCGATTGCCGATCACTATCTGCGGCATAGGGGACAGACGGGGAAGGGAATAGGCAGTAGGGAATAG

Upstream 100 bases:

>100_bases
GTCAAAACTTAAACGGCAGGGATGACAGTTTGACCACCGCAAAAAACGCCAATAGAAGGCAGGCATCAACCGGCTCCGCT
GCCGGGCAGGGCACTTTTCC

Downstream 100 bases:

>100_bases
GCAGTAGGCCGCCCGAAACAGCCTTTTTCTTCCCTACTGCCTACTCCCTAATCCCTGCGAGCGAAGCGAGCATCCCATGC
CTTACGACCAGAAGAAGATT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSHNTFGHLFRVTTWGESHGAALGCVVDGCPPGIRFTRDEIQAELDKRRPGQSRFVTQRREPDEVKVLSGFVLDEDGETM
ITTGTPVSMLIENVDQRSKDYGEIARQYRPGHADYTYDVKYGIRDYRGGGRSSARETAARVAAGALARKVVPGMVVRGAL
VSMGEKSIDRANWNWNFIGDAENPFFTPDPASVPVFTQYLDGIRKAGSSVGAVIEIVADGVPPGLGAPIYAKLDQDIASG
LMSINAVKGVEIGNGFEAARITGEQNADEMRIGNDGKPVFLSNNAGGILGGISTGQAIVARFAVKPTSSILTPRKSIDKD
GNDVEVMTKGRHDPCVGIRAVPIGEAMVACAIADHYLRHRGQTGKGIGSRE

Sequences:

>Translated_371_residues
MSHNTFGHLFRVTTWGESHGAALGCVVDGCPPGIRFTRDEIQAELDKRRPGQSRFVTQRREPDEVKVLSGFVLDEDGETM
ITTGTPVSMLIENVDQRSKDYGEIARQYRPGHADYTYDVKYGIRDYRGGGRSSARETAARVAAGALARKVVPGMVVRGAL
VSMGEKSIDRANWNWNFIGDAENPFFTPDPASVPVFTQYLDGIRKAGSSVGAVIEIVADGVPPGLGAPIYAKLDQDIASG
LMSINAVKGVEIGNGFEAARITGEQNADEMRIGNDGKPVFLSNNAGGILGGISTGQAIVARFAVKPTSSILTPRKSIDKD
GNDVEVMTKGRHDPCVGIRAVPIGEAMVACAIADHYLRHRGQTGKGIGSRE
>Mature_370_residues
SHNTFGHLFRVTTWGESHGAALGCVVDGCPPGIRFTRDEIQAELDKRRPGQSRFVTQRREPDEVKVLSGFVLDEDGETMI
TTGTPVSMLIENVDQRSKDYGEIARQYRPGHADYTYDVKYGIRDYRGGGRSSARETAARVAAGALARKVVPGMVVRGALV
SMGEKSIDRANWNWNFIGDAENPFFTPDPASVPVFTQYLDGIRKAGSSVGAVIEIVADGVPPGLGAPIYAKLDQDIASGL
MSINAVKGVEIGNGFEAARITGEQNADEMRIGNDGKPVFLSNNAGGILGGISTGQAIVARFAVKPTSSILTPRKSIDKDG
NDVEVMTKGRHDPCVGIRAVPIGEAMVACAIADHYLRHRGQTGKGIGSRE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=365, Percent_Identity=57.2602739726027, Blast_Score=396, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6321290, Length=373, Percent_Identity=38.8739946380697, Blast_Score=259, Evalue=4e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_RHILO (Q985Z4)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_107773.1
- HSSP:   P28777
- ProteinModelPortal:   Q985Z4
- SMR:   Q985Z4
- GeneID:   1230428
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr7461
- NMPDR:   fig|266835.1.peg.5874
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- BRENDA:   4.2.3.5
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39730; Mature: 39599

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHNTFGHLFRVTTWGESHGAALGCVVDGCPPGIRFTRDEIQAELDKRRPGQSRFVTQRR
CCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCEECHHHHHHHHHHCCCCCHHHHHCCC
EPDEVKVLSGFVLDEDGETMITTGTPVSMLIENVDQRSKDYGEIARQYRPGHADYTYDVK
CCCCEEEEEEEEECCCCCEEEECCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEEEE
YGIRDYRGGGRSSARETAARVAAGALARKVVPGMVVRGALVSMGEKSIDRANWNWNFIGD
ECCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEECC
AENPFFTPDPASVPVFTQYLDGIRKAGSSVGAVIEIVADGVPPGLGAPIYAKLDQDIASG
CCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LMSINAVKGVEIGNGFEAARITGEQNADEMRIGNDGKPVFLSNNAGGILGGISTGQAIVA
HHHHHHCCCEECCCCCCEEEECCCCCCCCEEECCCCCEEEEECCCCCEEECCCCCHHHHH
RFAVKPTSSILTPRKSIDKDGNDVEVMTKGRHDPCVGIRAVPIGEAMVACAIADHYLRHR
HHHCCCCHHHCCCHHHCCCCCCCEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHC
GQTGKGIGSRE
CCCCCCCCCCC
>Mature Secondary Structure 
SHNTFGHLFRVTTWGESHGAALGCVVDGCPPGIRFTRDEIQAELDKRRPGQSRFVTQRR
CCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCEECHHHHHHHHHHCCCCCHHHHHCCC
EPDEVKVLSGFVLDEDGETMITTGTPVSMLIENVDQRSKDYGEIARQYRPGHADYTYDVK
CCCCEEEEEEEEECCCCCEEEECCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEEEE
YGIRDYRGGGRSSARETAARVAAGALARKVVPGMVVRGALVSMGEKSIDRANWNWNFIGD
ECCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEECC
AENPFFTPDPASVPVFTQYLDGIRKAGSSVGAVIEIVADGVPPGLGAPIYAKLDQDIASG
CCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LMSINAVKGVEIGNGFEAARITGEQNADEMRIGNDGKPVFLSNNAGGILGGISTGQAIVA
HHHHHHCCCEECCCCCCEEEECCCCCCCCEEECCCCCEEEEECCCCCEEECCCCCHHHHH
RFAVKPTSSILTPRKSIDKDGNDVEVMTKGRHDPCVGIRAVPIGEAMVACAIADHYLRHR
HHHCCCCHHHCCCHHHCCCCCCCEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHC
GQTGKGIGSRE
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968