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The map label for this gene is ribH

Identifier: 13476065

GI number: 13476065

Start: 6016656

End: 6017129

Strand: Reverse

Name: ribH

Synonym: mll7281

Alternate gene names: 13476065

Gene position: 6017129-6016656 (Counterclockwise)

Preceding gene: 13476066

Following gene: 13476064

Centisome position: 85.52

GC content: 61.81

Gene sequence:

>474_bases
ATGAATCAGCATTCCCACAAAGACTATGAAACTGTTCGCATCGCCGTCGTCCGCGCGCGCTGGCATGCGGATATCGTCGA
CCAATGCGTCAGCGCTTTCGAGGCGGAGATGGCCGACATCGGAGGCGACCGTTTCGCCGTCGATGTCTTCGACGTGCCCG
GCGCCTACGAAATCCCGCTGCATGCCAGGACCTTGGCTGAGACCGGCCGCTATGGCGCGGTCCTCGGCACGGCTTTCGTC
GTCAATGGCGGCATCTACCGGCATGAATTCGTCGCCAGCGCCGTCATCGACGGCATGATGAACGTGCAGCTGTCAACCGG
CGTTCCGGTGCTTTCGGCGGTGCTCACGCCGCACAATTATCACGACAGCGCCGAGCACCATCGCTTCTTCTTCGAGCACT
TCACCGTCAAGGGCAAGGAAGCGGCCAGGGCCTGCGTGGAAATTCTCGCCGCGCGGGAAAAGATCGCGGCATGA

Upstream 100 bases:

>100_bases
AGTCCGGATGAAAGAGGACGAAACGGAAAACGGACCGCTCCGGCGGGCCGGATTGCGTGTCGTGCGTCCTGATTCTGGTT
CGAAACGGAAGGATGGACCC

Downstream 100 bases:

>100_bases
AATCTTCCCGGCCGGGTGGAAATCGCGATAACACCCGGTAGTATTTGCGAAAACTCGGGAGGATGCCGGTGCAGACCAAG
AAGATCATCAATGACGGCAA

Product: riboflavin synthase subunit beta

Products: NA

Alternate protein names: DMRL synthase 1; Lumazine synthase 1; Riboflavin synthase 1 beta chain

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MNQHSHKDYETVRIAVVRARWHADIVDQCVSAFEAEMADIGGDRFAVDVFDVPGAYEIPLHARTLAETGRYGAVLGTAFV
VNGGIYRHEFVASAVIDGMMNVQLSTGVPVLSAVLTPHNYHDSAEHHRFFFEHFTVKGKEAARACVEILAAREKIAA

Sequences:

>Translated_157_residues
MNQHSHKDYETVRIAVVRARWHADIVDQCVSAFEAEMADIGGDRFAVDVFDVPGAYEIPLHARTLAETGRYGAVLGTAFV
VNGGIYRHEFVASAVIDGMMNVQLSTGVPVLSAVLTPHNYHDSAEHHRFFFEHFTVKGKEAARACVEILAAREKIAA
>Mature_157_residues
MNQHSHKDYETVRIAVVRARWHADIVDQCVSAFEAEMADIGGDRFAVDVFDVPGAYEIPLHARTLAETGRYGAVLGTAFV
VNGGIYRHEFVASAVIDGMMNVQLSTGVPVLSAVLTPHNYHDSAEHHRFFFEHFTVKGKEAARACVEILAAREKIAA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=146, Percent_Identity=32.1917808219178, Blast_Score=64, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB1_RHILO (Q986N2)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_107635.1
- PDB:   2OBX
- PDBsum:   2OBX
- ProteinModelPortal:   Q986N2
- SMR:   Q986N2
- GeneID:   1230290
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll7281
- NMPDR:   fig|266835.1.peg.5736
- HOGENOM:   HBG311126
- OMA:   RRYTAIV
- ProtClustDB:   PRK12419
- BRENDA:   2.5.1.9
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 17281; Mature: 17281

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQHSHKDYETVRIAVVRARWHADIVDQCVSAFEAEMADIGGDRFAVDVFDVPGAYEIPL
CCCCCCCCHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEECCC
HARTLAETGRYGAVLGTAFVVNGGIYRHEFVASAVIDGMMNVQLSTGVPVLSAVLTPHNY
HHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEECCCCHHHHHHHCCCCC
HDSAEHHRFFFEHFTVKGKEAARACVEILAAREKIAA
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNQHSHKDYETVRIAVVRARWHADIVDQCVSAFEAEMADIGGDRFAVDVFDVPGAYEIPL
CCCCCCCCHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEECCC
HARTLAETGRYGAVLGTAFVVNGGIYRHEFVASAVIDGMMNVQLSTGVPVLSAVLTPHNY
HHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEECCCCHHHHHHHCCCCC
HDSAEHHRFFFEHFTVKGKEAARACVEILAAREKIAA
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968