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The map label for this gene is fabG [H]

Identifier: 13475996

GI number: 13475996

Start: 5944310

End: 5945101

Strand: Reverse

Name: fabG [H]

Synonym: mll7199

Alternate gene names: 13475996

Gene position: 5945101-5944310 (Counterclockwise)

Preceding gene: 13475997

Following gene: 13475995

Centisome position: 84.49

GC content: 65.78

Gene sequence:

>792_bases
ATGACCATGCTTCTTGGCAAGACGATCCTCATCACCGGCGTCGCTTCCGGCATCGGCGCGCGCACGGCGGAACTCGCCGG
CCAGCTTGGCGCGGATGTGATCGGCGTGGATGTCCGTGAGCCGGCGGCAGCGGCGGGCAGTTTCGTCAAGGCCGATATTT
CGTCGAAGGCCGGCGTCGACGAGTTGGTCGCGCGCCTGCCGCAGCGCATCGATGCGCTGTGCAATGTCGCCGGCCTGTCC
GGCAACACCGGCGCGGCAGCGACGCTGGCCGTCAACTTCTTCGGGCTGCGGGCGCTTTCGGAAAGCCTCGCTCCCAGACT
TCGCGAAGGCGGTGCCATCGTCAATGTCGCGTCGATCGCCGGCTATGGCTGGCGCGCCAATCTCAACCGTGCGGCCTCGA
TGGTCGGCATCGAGGGTTTCCCGGATGTCGCCAAGGTGGTCGCCGACCACGCGGTCAAGAACGAGGAAGGCTATCCCGTC
TCGAAGGAACTGCTCCTGCTGTGGACCTTCCGCGCGGCGCATCAGGATCTGTTCAAGAGCCGTGGCATCCGCGTCAATGC
GGTGAGTCCCGGACCGGTCGAGACGCCTATCCTGAAACAATTCCGCACAGTGCTTGGCGATGCGCGCGTCGACAGCGACA
TTGCCAGGGTCGGACGAGCCGGCACATCGGGCGATATAGCGCCTGTCGTGCTGTTCCTATGCTCGGACGGCGCGCGCTGG
GTCAACGGCGCCAACGTGCCGGTCGACGGCGGCCTCGAAGCATCGATCAACGCCGAAGGGCTCGGCTTCTAA

Upstream 100 bases:

>100_bases
TGCTGCCGGTCGGCTACCGCGTCAGGCTTCCGGGGAATGCTCGGGCCGACAAAGGCACCGACCCTTCGCCGGAGCGAACC
ACTCTTGATCAGGAGAAGGC

Downstream 100 bases:

>100_bases
TTGCGAAGCTCCACCGGAGCGAGGGAGACAATCATGGATATCGGACTTCTGATCGACGGCGACAAAAGGGATGCGTCCGG
CGCGGCCGCCTACGAGCGTC

Product: 3-alpha-hydroxysteroid dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MTMLLGKTILITGVASGIGARTAELAGQLGADVIGVDVREPAAAAGSFVKADISSKAGVDELVARLPQRIDALCNVAGLS
GNTGAAATLAVNFFGLRALSESLAPRLREGGAIVNVASIAGYGWRANLNRAASMVGIEGFPDVAKVVADHAVKNEEGYPV
SKELLLLWTFRAAHQDLFKSRGIRVNAVSPGPVETPILKQFRTVLGDARVDSDIARVGRAGTSGDIAPVVLFLCSDGARW
VNGANVPVDGGLEASINAEGLGF

Sequences:

>Translated_263_residues
MTMLLGKTILITGVASGIGARTAELAGQLGADVIGVDVREPAAAAGSFVKADISSKAGVDELVARLPQRIDALCNVAGLS
GNTGAAATLAVNFFGLRALSESLAPRLREGGAIVNVASIAGYGWRANLNRAASMVGIEGFPDVAKVVADHAVKNEEGYPV
SKELLLLWTFRAAHQDLFKSRGIRVNAVSPGPVETPILKQFRTVLGDARVDSDIARVGRAGTSGDIAPVVLFLCSDGARW
VNGANVPVDGGLEASINAEGLGF
>Mature_262_residues
TMLLGKTILITGVASGIGARTAELAGQLGADVIGVDVREPAAAAGSFVKADISSKAGVDELVARLPQRIDALCNVAGLSG
NTGAAATLAVNFFGLRALSESLAPRLREGGAIVNVASIAGYGWRANLNRAASMVGIEGFPDVAKVVADHAVKNEEGYPVS
KELLLLWTFRAAHQDLFKSRGIRVNAVSPGPVETPILKQFRTVLGDARVDSDIARVGRAGTSGDIAPVVLFLCSDGARWV
NGANVPVDGGLEASINAEGLGF

Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17555706, Length=279, Percent_Identity=29.3906810035842, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24639444, Length=279, Percent_Identity=28.673835125448, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28571526, Length=285, Percent_Identity=29.4736842105263, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21357041, Length=285, Percent_Identity=29.8245614035088, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI23397609, Length=274, Percent_Identity=30.2919708029197, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27057; Mature: 26926

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMLLGKTILITGVASGIGARTAELAGQLGADVIGVDVREPAAAAGSFVKADISSKAGVD
CCEEECCCEEEEHHHHCCCHHHHHHHHHHCCCEEEECCCCCHHHHCCHHEECCCCCCCHH
ELVARLPQRIDALCNVAGLSGNTGAAATLAVNFFGLRALSESLAPRLREGGAIVNVASIA
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHC
GYGWRANLNRAASMVGIEGFPDVAKVVADHAVKNEEGYPVSKELLLLWTFRAAHQDLFKS
CCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RGIRVNAVSPGPVETPILKQFRTVLGDARVDSDIARVGRAGTSGDIAPVVLFLCSDGARW
CCCEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCCCC
VNGANVPVDGGLEASINAEGLGF
CCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TMLLGKTILITGVASGIGARTAELAGQLGADVIGVDVREPAAAAGSFVKADISSKAGVD
CEEECCCEEEEHHHHCCCHHHHHHHHHHCCCEEEECCCCCHHHHCCHHEECCCCCCCHH
ELVARLPQRIDALCNVAGLSGNTGAAATLAVNFFGLRALSESLAPRLREGGAIVNVASIA
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHC
GYGWRANLNRAASMVGIEGFPDVAKVVADHAVKNEEGYPVSKELLLLWTFRAAHQDLFKS
CCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RGIRVNAVSPGPVETPILKQFRTVLGDARVDSDIARVGRAGTSGDIAPVVLFLCSDGARW
CCCEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCCCC
VNGANVPVDGGLEASINAEGLGF
CCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]