Click here to switch to the map view.

The map label for this gene is kdgR [H]

Identifier: 13475958

GI number: 13475958

Start: 5907221

End: 5908006

Strand: Direct

Name: kdgR [H]

Synonym: mlr7155

Alternate gene names: 13475958

Gene position: 5907221-5908006 (Clockwise)

Preceding gene: 13475949

Following gene: 13475959

Centisome position: 83.96

GC content: 63.23

Gene sequence:

>786_bases
ATGGATGACAGCGAAGACGAGCGCTACCGCGCGCCGGCGCTCGACAAGGGGCTCGACATTCTTGAGCTGCTGGCCGGCGT
CGACGGCGGCCTGACCCAGGCCGAAATCGCCAAGAAACTCGACCGCAGCCCGAACGAATTCTACCGCATGCTCGACCGGC
TGGTGCGGCGCGGCTATGTCACAAGGCTGGATGGCGACCGCTATTCACTGACGTTGAAACTGTTCGGCTTGGCGCAATTG
CACGCTCCGGTGCGGCGGCTGGTCTCCTACGCCACGCCGCTGATGCGCGAGCTAGCCGAGACTTCGCAGCAGGCCAACCA
ACTCGTTGTTTTTGATCGTGGTTCCGCCGTCGTTATTGCCCAACAGGAGGCGCCGAACTACTGGGGCATCTCGATCCGGG
TGGGCTCCCACATCAGCCTGTTCGACACGGGTTCTGGCCATGTGCTGCTCGCATTCCGCTCGCAGGAAGAGCGGCAGATG
ATGATCTCCGAACATGTCCGCAGCACCGACAAGACGGCGCAGTCGGTCGAGTTCTTCACCCGGCTCGACCAGATCCGCGA
CCGTGGCTACGAGATGATGGCCTCGATGCAGACCGCCGGCGTCTTCAACCTGTCGGCGCCGGTGCGCAGTTCCGACGGCA
AGGCCATCGCCGCCCTGTCGATCCCCTACATCACCGTCATCAACACGCCTTCCGCGCCCGACATCACCCGGACCATCGAG
TTGTTGCTGGTCACGACCGAGAAGCTGTCGCATCTGGCCGGATCGGCTGTAGGGTCGGCAGCATAA

Upstream 100 bases:

>100_bases
ATACAAACAAAACATTCATACATACGTCAAGGCGAAATTTTGTTTCCGCCGGCCGCATTCCTGCGTATATGAAGGGCAGA
ATTCACTGGAGAAATGCCTC

Downstream 100 bases:

>100_bases
ATTCTTATTTGAATGAAGAATTCCTCCGTGAGATTATCTGACCAAAGCCAATTGGGAGGAGCTCCAGTGATCATCGACAC
CCATCTGCATCTCATCGATC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MDDSEDERYRAPALDKGLDILELLAGVDGGLTQAEIAKKLDRSPNEFYRMLDRLVRRGYVTRLDGDRYSLTLKLFGLAQL
HAPVRRLVSYATPLMRELAETSQQANQLVVFDRGSAVVIAQQEAPNYWGISIRVGSHISLFDTGSGHVLLAFRSQEERQM
MISEHVRSTDKTAQSVEFFTRLDQIRDRGYEMMASMQTAGVFNLSAPVRSSDGKAIAALSIPYITVINTPSAPDITRTIE
LLLVTTEKLSHLAGSAVGSAA

Sequences:

>Translated_261_residues
MDDSEDERYRAPALDKGLDILELLAGVDGGLTQAEIAKKLDRSPNEFYRMLDRLVRRGYVTRLDGDRYSLTLKLFGLAQL
HAPVRRLVSYATPLMRELAETSQQANQLVVFDRGSAVVIAQQEAPNYWGISIRVGSHISLFDTGSGHVLLAFRSQEERQM
MISEHVRSTDKTAQSVEFFTRLDQIRDRGYEMMASMQTAGVFNLSAPVRSSDGKAIAALSIPYITVINTPSAPDITRTIE
LLLVTTEKLSHLAGSAVGSAA
>Mature_261_residues
MDDSEDERYRAPALDKGLDILELLAGVDGGLTQAEIAKKLDRSPNEFYRMLDRLVRRGYVTRLDGDRYSLTLKLFGLAQL
HAPVRRLVSYATPLMRELAETSQQANQLVVFDRGSAVVIAQQEAPNYWGISIRVGSHISLFDTGSGHVLLAFRSQEERQM
MISEHVRSTDKTAQSVEFFTRLDQIRDRGYEMMASMQTAGVFNLSAPVRSSDGKAIAALSIPYITVINTPSAPDITRTIE
LLLVTTEKLSHLAGSAVGSAA

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=196, Percent_Identity=32.1428571428571, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788581, Length=218, Percent_Identity=26.1467889908257, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082359, Length=215, Percent_Identity=22.7906976744186, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28833; Mature: 28833

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDSEDERYRAPALDKGLDILELLAGVDGGLTQAEIAKKLDRSPNEFYRMLDRLVRRGYV
CCCCCCCCCCCCCHHCCHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCE
TRLDGDRYSLTLKLFGLAQLHAPVRRLVSYATPLMRELAETSQQANQLVVFDRGSAVVIA
EEECCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEE
QQEAPNYWGISIRVGSHISLFDTGSGHVLLAFRSQEERQMMISEHVRSTDKTAQSVEFFT
ECCCCCEEEEEEEECCEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
RLDQIRDRGYEMMASMQTAGVFNLSAPVRSSDGKAIAALSIPYITVINTPSAPDITRTIE
HHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCEEEEEECCEEEEEECCCCCCHHHHHH
LLLVTTEKLSHLAGSAVGSAA
HEEEEHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDDSEDERYRAPALDKGLDILELLAGVDGGLTQAEIAKKLDRSPNEFYRMLDRLVRRGYV
CCCCCCCCCCCCCHHCCHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCE
TRLDGDRYSLTLKLFGLAQLHAPVRRLVSYATPLMRELAETSQQANQLVVFDRGSAVVIA
EEECCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEE
QQEAPNYWGISIRVGSHISLFDTGSGHVLLAFRSQEERQMMISEHVRSTDKTAQSVEFFT
ECCCCCEEEEEEEECCEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
RLDQIRDRGYEMMASMQTAGVFNLSAPVRSSDGKAIAALSIPYITVINTPSAPDITRTIE
HHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCEEEEEECCEEEEEECCCCCCHHHHHH
LLLVTTEKLSHLAGSAVGSAA
HEEEEHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]