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The map label for this gene is eutB [C]

Identifier: 13475944

GI number: 13475944

Start: 5893121

End: 5894179

Strand: Direct

Name: eutB [C]

Synonym: mlr7138

Alternate gene names: 13475944

Gene position: 5893121-5894179 (Clockwise)

Preceding gene: 13475943

Following gene: 13475945

Centisome position: 83.76

GC content: 65.63

Gene sequence:

>1059_bases
GTGTGGCGACGAGACGCCGCGCCCCGAATTTGGGCAGCTGATGACGCTTCCTCTGCCGCGCGATTGATGATCATGACGAC
CGTCTCCCTTAACGATATCCGCGCCGCGCGTGAGCGTATTGCCAGCAAGGTCGAGTACACGCCGACTGTTTTATCCTCGA
GCCTTTCGGAACGTCTCGGTGTCCCCGTCCATCTCAAGCTCGAGCATCGCCAGACTACCGGCAGCTTCAAGCTCCGCGGC
GCCACGAATGCCGTCTCTTCGCTGAGCGCGGAAGAAAAGGCAGGCGGTGTGGTCGCGGCCTCGACCGGCAACCATGGCCG
GGCGCTGGCACATGCTGCGAAGCTCGAAGGCATGCGCGCGGTGATCTGCATGTCGCGGCTGGTGCCCCAGAACAAGCTCG
ACGAAATCCGCCGGCTCGGCGCCGAGGTCCACATCGTCGGCAACAGCCAGGACGATGCCCAGCAGGAGGTTGAGCGGCTG
GTGGCGCAGCAGGGGCTGGTGATGCTGCCGCCTTTCGACAATCCCGCCATCATCGCCGGGCAAGGCACGCTCGGGCTGGA
GATGATCGAGCAGGTCCCGGATGCCGCTCTGGTGCTTGTGCAACTCTCCGGCGGTGGCCTGGCTTCCGGCGTCGCCACAG
CCGTCAAGGGCATCAGGCCCGGGACAGAAGTCATCGGCGTTTCGATGGCGCGGGGTGCTGCGATGAAGGCGAGCCTCGAT
GCCGGCCGGCCTGTCCTGGTGGAGGAACTGCCGACGTTGGCGGACTCGCTGGGTGGCGGCATCGGCCTCGACAACAGGCT
GACCTTCGCCATGTGCCGCGACCTGCTCGACGAAATCATCTTGCTCAGCGAGGACGAGATCGCCGCAGGTATCTGCCATG
CCTATGCGCAGGAGCGCGAGATCGTCGAGGGCGCCGGCGCGGTCGGCATCGCAGCGCTTCTCGCCGGCAAGGTCAAGGCG
AAAGGGCCGATGGTCGTACTTCTCTCCGGCCGCAACATCGACATGAATGCGCACCGCCGGATCATCTGCGGCGAGGCAAT
CGGGGAGCGCGCCGCATGA

Upstream 100 bases:

>100_bases
CGGCGCTGCGCGGCGCGCTTGCGGTCACCGGCATGGAACAGGCAATCGGCCGTCCTGTAGTGACCAGCAACCAAGCGACA
GCCTGGAACTGCTTGCGGCT

Downstream 100 bases:

>100_bases
GCCGTATGACGATTCTGACCGAAGCAGAACTGCGCAAGATCGTAACGCTCGATCTCGACGCCGTCGCCTGCGTCGAGAAC
GCTTTTCGCGCGCTCGCCAC

Product: threonine dehydratase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MWRRDAAPRIWAADDASSAARLMIMTTVSLNDIRAARERIASKVEYTPTVLSSSLSERLGVPVHLKLEHRQTTGSFKLRG
ATNAVSSLSAEEKAGGVVAASTGNHGRALAHAAKLEGMRAVICMSRLVPQNKLDEIRRLGAEVHIVGNSQDDAQQEVERL
VAQQGLVMLPPFDNPAIIAGQGTLGLEMIEQVPDAALVLVQLSGGGLASGVATAVKGIRPGTEVIGVSMARGAAMKASLD
AGRPVLVEELPTLADSLGGGIGLDNRLTFAMCRDLLDEIILLSEDEIAAGICHAYAQEREIVEGAGAVGIAALLAGKVKA
KGPMVVLLSGRNIDMNAHRRIICGEAIGERAA

Sequences:

>Translated_352_residues
MWRRDAAPRIWAADDASSAARLMIMTTVSLNDIRAARERIASKVEYTPTVLSSSLSERLGVPVHLKLEHRQTTGSFKLRG
ATNAVSSLSAEEKAGGVVAASTGNHGRALAHAAKLEGMRAVICMSRLVPQNKLDEIRRLGAEVHIVGNSQDDAQQEVERL
VAQQGLVMLPPFDNPAIIAGQGTLGLEMIEQVPDAALVLVQLSGGGLASGVATAVKGIRPGTEVIGVSMARGAAMKASLD
AGRPVLVEELPTLADSLGGGIGLDNRLTFAMCRDLLDEIILLSEDEIAAGICHAYAQEREIVEGAGAVGIAALLAGKVKA
KGPMVVLLSGRNIDMNAHRRIICGEAIGERAA
>Mature_352_residues
MWRRDAAPRIWAADDASSAARLMIMTTVSLNDIRAARERIASKVEYTPTVLSSSLSERLGVPVHLKLEHRQTTGSFKLRG
ATNAVSSLSAEEKAGGVVAASTGNHGRALAHAAKLEGMRAVICMSRLVPQNKLDEIRRLGAEVHIVGNSQDDAQQEVERL
VAQQGLVMLPPFDNPAIIAGQGTLGLEMIEQVPDAALVLVQLSGGGLASGVATAVKGIRPGTEVIGVSMARGAAMKASLD
AGRPVLVEELPTLADSLGGGIGLDNRLTFAMCRDLLDEIILLSEDEIAAGICHAYAQEREIVEGAGAVGIAALLAGKVKA
KGPMVVLLSGRNIDMNAHRRIICGEAIGERAA

Specific function: Acts On Both Serine And Threonine, And Properly Considered As A Hydroxy Amino Acid Deaminase. [C]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=319, Percent_Identity=34.1692789968652, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI19923959, Length=304, Percent_Identity=29.2763157894737, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI33469958, Length=306, Percent_Identity=27.4509803921569, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI1789505, Length=312, Percent_Identity=37.8205128205128, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1790207, Length=308, Percent_Identity=35.3896103896104, Blast_Score=156, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71991565, Length=313, Percent_Identity=37.3801916932907, Blast_Score=164, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17537387, Length=322, Percent_Identity=38.5093167701863, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17508781, Length=322, Percent_Identity=29.8136645962733, Blast_Score=131, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6322631, Length=327, Percent_Identity=35.474006116208, Blast_Score=163, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6320930, Length=323, Percent_Identity=33.1269349845201, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6319788, Length=260, Percent_Identity=25, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355833, Length=318, Percent_Identity=37.4213836477987, Blast_Score=148, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24645328, Length=222, Percent_Identity=36.9369369369369, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014333
- InterPro:   IPR001926
- InterPro:   IPR000634 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 36876; Mature: 36876

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWRRDAAPRIWAADDASSAARLMIMTTVSLNDIRAARERIASKVEYTPTVLSSSLSERLG
CCCCCCCCCEEECCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
VPVHLKLEHRQTTGSFKLRGATNAVSSLSAEEKAGGVVAASTGNHGRALAHAAKLEGMRA
CCEEEEEECCCCCCCEEECCCHHHHHHCCCHHHCCCEEEECCCCCCHHHHHHHHHCCHHH
VICMSRLVPQNKLDEIRRLGAEVHIVGNSQDDAQQEVERLVAQQGLVMLPPFDNPAIIAG
HHHHHHHCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCEEEECCCCCCEEEEC
QGTLGLEMIEQVPDAALVLVQLSGGGLASGVATAVKGIRPGTEVIGVSMARGAAMKASLD
CCCHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHCCCCCHHHEEEHHHCCCHHEECCC
AGRPVLVEELPTLADSLGGGIGLDNRLTFAMCRDLLDEIILLSEDEIAAGICHAYAQERE
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
IVEGAGAVGIAALLAGKVKAKGPMVVLLSGRNIDMNAHRRIICGEAIGERAA
HHHCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEECHHHCCCCC
>Mature Secondary Structure
MWRRDAAPRIWAADDASSAARLMIMTTVSLNDIRAARERIASKVEYTPTVLSSSLSERLG
CCCCCCCCCEEECCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
VPVHLKLEHRQTTGSFKLRGATNAVSSLSAEEKAGGVVAASTGNHGRALAHAAKLEGMRA
CCEEEEEECCCCCCCEEECCCHHHHHHCCCHHHCCCEEEECCCCCCHHHHHHHHHCCHHH
VICMSRLVPQNKLDEIRRLGAEVHIVGNSQDDAQQEVERLVAQQGLVMLPPFDNPAIIAG
HHHHHHHCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCEEEECCCCCCEEEEC
QGTLGLEMIEQVPDAALVLVQLSGGGLASGVATAVKGIRPGTEVIGVSMARGAAMKASLD
CCCHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHCCCCCHHHEEEHHHCCCHHEECCC
AGRPVLVEELPTLADSLGGGIGLDNRLTFAMCRDLLDEIILLSEDEIAAGICHAYAQERE
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
IVEGAGAVGIAALLAGKVKAKGPMVVLLSGRNIDMNAHRRIICGEAIGERAA
HHHCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEECHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]